LOCUS       NM_001399009             991 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus mitochondrial ribosomal protein L15 (Mrpl15),
            transcript variant 5, mRNA.
ACCESSION   NM_001399009 XM_039109397
VERSION     NM_001399009.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Brown,A., Rathore,S., Kimanius,D., Aibara,S., Bai,X.C., Rorbach,J.,
            Amunts,A. and Ramakrishnan,V.
  TITLE     Structures of the human mitochondrial ribosome in native states of
            assembly
  JOURNAL   Nat Struct Mol Biol 24 (10), 866-869 (2017)
   PUBMED   28892042
REFERENCE   2  (bases 1 to 991)
  AUTHORS   Brown,A., Amunts,A., Bai,X.C., Sugimoto,Y., Edwards,P.C.,
            Murshudov,G., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Structure of the large ribosomal subunit from human mitochondria
  JOURNAL   Science 346 (6210), 718-722 (2014)
   PUBMED   25278503
REFERENCE   3  (bases 1 to 991)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 991)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 991)
  AUTHORS   Tarantino,C., Paolella,G., Cozzuto,L., Minopoli,G., Pastore,L.,
            Parisi,S. and Russo,T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
REFERENCE   6  (bases 1 to 991)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Dec 29, 2021 this sequence version replaced XM_039109397.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22399492.186148.1,
                                           SRR26360186.1475709.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760434
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-173               JAXUCZ010000005.1  19527746-19527918
            174-328             JAXUCZ010000005.1  19529227-19529381
            329-494             JAXUCZ010000005.1  19530084-19530249
            495-991             JAXUCZ010000005.1  19535668-19536164
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q12"
     gene            1..991
                     /gene="Mrpl15"
                     /note="mitochondrial ribosomal protein L15"
                     /db_xref="GeneID:297799"
                     /db_xref="RGD:1304796"
     exon            1..173
                     /gene="Mrpl15"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..656
                     /gene="Mrpl15"
                     /EC_number="3.6.5.3"
                     /note="isoform 5 is encoded by transcript variant 5; 39S
                     ribosomal protein L15, mitochondrial; large ribosomal
                     subunit protein uL15m"
                     /codon_start=1
                     /product="large ribosomal subunit protein uL15m isoform 5"
                     /protein_id="NP_001385938.1"
                     /db_xref="GeneID:297799"
                     /db_xref="RGD:1304796"
                     /translation="MAGMAFGRGTSLDLLRSLPRVSLANLKPSLNSRKRERRPRDRRR
                     GRKCGRGHKGERQRGTRPRLGFEGGQTPFYIRIPKYGFNEGHSFRHQYQPLSLRRLQY
                     LIDLGRVDPTQPIDLTQLVNGRGVTIQPLKRDYGVQLVEEKFCASLFHSFCADNPFQR
                     ECFHPRRWCPIIPMRKTGGTWPTLPSFLKQDWNLP"
     exon            174..328
                     /gene="Mrpl15"
                     /inference="alignment:Splign:2.1.0"
     exon            329..494
                     /gene="Mrpl15"
                     /inference="alignment:Splign:2.1.0"
     exon            495..991
                     /gene="Mrpl15"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggcgtggc cgtaaagcaa tgcggagcct tcgccgcctt ctgggcgccc ttgaaaggac
       61 cgtgggccat ggctggcatg gcgtttggcc gcgggaccag tctggacctt ctgcggtcct
      121 tgccgagagt gagcctggcc aatctgaagc ccagtcttaa ctccagaaaa cgggaaagac
      181 gtccaagaga tcggagaaga ggtaggaagt gtggcagagg ccataaagga gaaagacaga
      241 gaggaacccg gcccaggctg ggctttgagg gagggcagac tccattttac atccgaatcc
      301 caaaatatgg atttaatgaa ggacatagtt tcaggcacca gtatcagcct ctgagtctca
      361 ggagactaca gtatctcatt gatttaggtc gagttgatcc aactcaacct attgacttaa
      421 cgcagcttgt gaatgggaga ggtgtgacca tccagccact taaaagggat tatggggtcc
      481 agctggttga agagaaattc tgtgcaagcc tgttccattc tttctgcgcg gacaacccat
      541 tccaaagaga atgcttccac ccgaggcgct ggtgccctat tataccgatg cgaaaaaccg
      601 ggggtacctg gccgaccctg ccaagtttcc tgaagcaaga ctggaacttg ccatgaagta
      661 tggctatgtc cttcctgatg tcacgaaaga cgaactcttc agaatgctca gcacccgcaa
      721 ggatccaagg cagattttct ttggtcttgc tcctggctgg atagtgaata tggcagataa
      781 gaaaattcta aaacctacag atgagaatct tctcaagtat tacagctcct gaactgcctt
      841 cagtaaatca gacatgtgag ccaggggggc tgaacacggg ctcgtgtggg ccttaaagcc
      901 gaggggctgg taccgcctgc actggtcagg tttcttgttc tttttccatc tgaaattaaa
      961 taacaggcag caaaagctgc atcggaactg a
//
