LOCUS       NM_001399003            1115 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus mitochondrial ribosomal protein L15 (Mrpl15),
            transcript variant 1, mRNA.
ACCESSION   NM_001399003 XM_006237805
VERSION     NM_001399003.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1115)
  AUTHORS   Brown,A., Rathore,S., Kimanius,D., Aibara,S., Bai,X.C., Rorbach,J.,
            Amunts,A. and Ramakrishnan,V.
  TITLE     Structures of the human mitochondrial ribosome in native states of
            assembly
  JOURNAL   Nat Struct Mol Biol 24 (10), 866-869 (2017)
   PUBMED   28892042
REFERENCE   2  (bases 1 to 1115)
  AUTHORS   Brown,A., Amunts,A., Bai,X.C., Sugimoto,Y., Edwards,P.C.,
            Murshudov,G., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Structure of the large ribosomal subunit from human mitochondria
  JOURNAL   Science 346 (6210), 718-722 (2014)
   PUBMED   25278503
REFERENCE   3  (bases 1 to 1115)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 1115)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 1115)
  AUTHORS   Tarantino,C., Paolella,G., Cozzuto,L., Minopoli,G., Pastore,L.,
            Parisi,S. and Russo,T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
REFERENCE   6  (bases 1 to 1115)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Dec 29, 2021 this sequence version replaced XM_006237805.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ214529.1, FQ221067.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-173               JAXUCZ010000005.1  19527746-19527918
            174-328             JAXUCZ010000005.1  19529227-19529381
            329-494             JAXUCZ010000005.1  19530084-19530249
            495-618             JAXUCZ010000005.1  19534929-19535052
            619-1115            JAXUCZ010000005.1  19535668-19536164
FEATURES             Location/Qualifiers
     source          1..1115
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q12"
     gene            1..1115
                     /gene="Mrpl15"
                     /note="mitochondrial ribosomal protein L15"
                     /db_xref="GeneID:297799"
                     /db_xref="RGD:1304796"
     exon            1..173
                     /gene="Mrpl15"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..956
                     /gene="Mrpl15"
                     /EC_number="3.6.5.3"
                     /note="isoform 1 is encoded by transcript variant 1; 39S
                     ribosomal protein L15, mitochondrial; large ribosomal
                     subunit protein uL15m"
                     /codon_start=1
                     /product="large ribosomal subunit protein uL15m isoform 1"
                     /protein_id="NP_001385932.1"
                     /db_xref="GeneID:297799"
                     /db_xref="RGD:1304796"
                     /translation="MAGMAFGRGTSLDLLRSLPRVSLANLKPSLNSRKRERRPRDRRR
                     GRKCGRGHKGERQRGTRPRLGFEGGQTPFYIRIPKYGFNEGHSFRHQYQPLSLRRLQY
                     LIDLGRVDPTQPIDLTQLVNGRGVTIQPLKRDYGVQLVEEGADTFQAKVNIEVQMASE
                     LAIAAIEKNGGVVTTAFYDPRSLEILCKPVPFFLRGQPIPKRMLPPEALVPYYTDAKN
                     RGYLADPAKFPEARLELAMKYGYVLPDVTKDELFRMLSTRKDPRQIFFGLAPGWIVNM
                     ADKKILKPTDENLLKYYSS"
     exon            174..328
                     /gene="Mrpl15"
                     /inference="alignment:Splign:2.1.0"
     exon            329..494
                     /gene="Mrpl15"
                     /inference="alignment:Splign:2.1.0"
     exon            495..618
                     /gene="Mrpl15"
                     /inference="alignment:Splign:2.1.0"
     exon            619..1115
                     /gene="Mrpl15"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggcgtggc cgtaaagcaa tgcggagcct tcgccgcctt ctgggcgccc ttgaaaggac
       61 cgtgggccat ggctggcatg gcgtttggcc gcgggaccag tctggacctt ctgcggtcct
      121 tgccgagagt gagcctggcc aatctgaagc ccagtcttaa ctccagaaaa cgggaaagac
      181 gtccaagaga tcggagaaga ggtaggaagt gtggcagagg ccataaagga gaaagacaga
      241 gaggaacccg gcccaggctg ggctttgagg gagggcagac tccattttac atccgaatcc
      301 caaaatatgg atttaatgaa ggacatagtt tcaggcacca gtatcagcct ctgagtctca
      361 ggagactaca gtatctcatt gatttaggtc gagttgatcc aactcaacct attgacttaa
      421 cgcagcttgt gaatgggaga ggtgtgacca tccagccact taaaagggat tatggggtcc
      481 agctggttga agagggtgct gatacttttc aagcaaaagt taatattgag gtgcagatgg
      541 cttcagaatt agccattgct gcaattgaaa aaaatggtgg tgttgttact acagccttct
      601 atgacccaag aagtctagaa attctgtgca agcctgttcc attctttctg cgcggacaac
      661 ccattccaaa gagaatgctt ccacccgagg cgctggtgcc ctattatacc gatgcgaaaa
      721 accgggggta cctggccgac cctgccaagt ttcctgaagc aagactggaa cttgccatga
      781 agtatggcta tgtccttcct gatgtcacga aagacgaact cttcagaatg ctcagcaccc
      841 gcaaggatcc aaggcagatt ttctttggtc ttgctcctgg ctggatagtg aatatggcag
      901 ataagaaaat tctaaaacct acagatgaga atcttctcaa gtattacagc tcctgaactg
      961 ccttcagtaa atcagacatg tgagccaggg gggctgaaca cgggctcgtg tgggccttaa
     1021 agccgagggg ctggtaccgc ctgcactggt caggtttctt gttctttttc catctgaaat
     1081 taaataacag gcagcaaaag ctgcatcgga actga
//
