LOCUS       NM_001108282            1472 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus mitochondrial rRNA methyltransferase 3 (Mrm3),
            mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001108282 XM_001080751 XM_340845
VERSION     NM_001108282.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1472)
  AUTHORS   Lee KW and Bogenhagen DF.
  TITLE     Assignment of 2'-O-methyltransferases to modification sites on the
            mammalian mitochondrial large subunit 16 S ribosomal RNA (rRNA)
  JOURNAL   J Biol Chem 289 (36), 24936-24942 (2014)
   PUBMED   25074936
REFERENCE   2  (bases 1 to 1472)
  AUTHORS   Lee KW, Okot-Kotber C, LaComb JF and Bogenhagen DF.
  TITLE     Mitochondrial ribosomal RNA (rRNA) methyltransferase family members
            are positioned to modify nascent rRNA in foci near the
            mitochondrial DNA nucleoid
  JOURNAL   J Biol Chem 288 (43), 31386-31399 (2013)
   PUBMED   24036117
REFERENCE   3  (bases 1 to 1472)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 1472)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001080751.1, XM_340845.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ232324.1, FQ233133.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1472
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..1472
                     /gene="Mrm3"
                     /gene_synonym="RGD1309077; Rnmtl1"
                     /note="mitochondrial rRNA methyltransferase 3"
                     /db_xref="GeneID:360569"
                     /db_xref="RGD:1309077"
     exon            1..325
                     /gene="Mrm3"
                     /gene_synonym="RGD1309077; Rnmtl1"
                     /inference="alignment:Splign:2.1.0"
     CDS             12..1268
                     /gene="Mrm3"
                     /gene_synonym="RGD1309077; Rnmtl1"
                     /note="RNA methyltransferase-like protein 1; RNA
                     methyltransferase like 1"
                     /codon_start=1
                     /product="rRNA methyltransferase 3, mitochondrial"
                     /protein_id="NP_001101752.1"
                     /db_xref="GeneID:360569"
                     /db_xref="RGD:1309077"
                     /translation="MAAPAKGMWYSLGPLLRVVQTRDLDARRWVRALRRSPVRVLFPS
                     GQVEERKRAPDKQPRKAVPEASSQGQQQKQPLETSPSQTPHTWEEAGLRYDKACPGDR
                     RLSSVMTIVKSRPFREKQGKILLEGRRLIADALKAGAVPKMFFFSRLEYIKELPVDKL
                     KGVSLIKVKFEDIKDWSDLVTPQGIMGIFAKPDPVKMTYPETQLHHSLPLLLICDNLR
                     DPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVNNVEWETVPN
                     HLPPDTRVYVADNCGLYAQVQMSNKTGDRDWACDRRFLKFHKNEVDLDTKARKDWLPK
                     LEVQSYDLDWTEAPAALVIGGETHGVSLESLQLAESTGGKRLLIPVVPGVDSLNSAMA
                     ASILLFEGKRQLRIKMGDLSRDSCCH"
     exon            326..570
                     /gene="Mrm3"
                     /gene_synonym="RGD1309077; Rnmtl1"
                     /inference="alignment:Splign:2.1.0"
     exon            571..738
                     /gene="Mrm3"
                     /gene_synonym="RGD1309077; Rnmtl1"
                     /inference="alignment:Splign:2.1.0"
     exon            739..1472
                     /gene="Mrm3"
                     /gene_synonym="RGD1309077; Rnmtl1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccagagcaaa gatggcagcg ccggcgaagg gcatgtggta ttccctggga ccattgctgc
       61 gggtggtcca gactcgggac ctcgacgctc ggcgctgggt ccgggcgctg cggcgaagcc
      121 cggtgagagt gttgtttccc tcgggacagg tggaggaacg gaagcgtgct cctgataagc
      181 agccccgcaa ggcggtccct gaggccagtt cccagggaca gcaacagaaa caacctcttg
      241 agacatcccc atcccagacc cctcacacct gggaagaggc agggcttcgc tacgataagg
      301 cctgtcccgg ggacaggagg ctaagcagtg tgatgacaat agttaagtcc aggccttttc
      361 gggaaaagca agggaagatc ctactggaag gtcgcaggct gattgcagat gctctcaagg
      421 ctggagctgt gccaaaaatg ttctttttta gccgactgga gtacatcaag gagttgccag
      481 tagataagct gaaaggtgtc agcctcatta aggtgaaatt tgaggatatc aaggattggt
      541 cggacctggt aacgccacaa ggaataatgg ggatttttgc caaacctgac cctgttaaga
      601 tgacgtatcc agagactcag cttcaccatt cactgccctt actgttgatt tgtgacaatc
      661 tccgtgaccc tgggaacctg gggacaatcc tgagatctgc agctggagca ggctgcagta
      721 aagtcttact caccaaaggc tgtgtggatg cctgggaacc taaagtgctc cgggcaggca
      781 tgggggcaca tttccaggtg cccattgtga acaatgtgga atgggagaca gtgcccaatc
      841 acttgccccc tgacacccga gtctatgtgg cagacaactg tggcctctat gcccaggttc
      901 agatgtctaa taaaaccggt gaccgtgact gggcatgtga tcgccgattc ttaaagttcc
      961 ataagaatga agtggaccta gacactaaag ccagaaaaga ctggcttccc aaacttgagg
     1021 tccagagtta tgatctggac tggactgaag caccagcagc tctggtgata ggcggagaga
     1081 cgcatggggt aagcctggag tccctgcaat tggccgagag tactggtggc aagagactgc
     1141 tgatccctgt tgtacctggt gtggacagtc tgaattcagc catggctgcg agcatcctgc
     1201 tctttgaagg gaaaaggcag ctgaggataa agatgggaga cttgagcagg gacagttgtt
     1261 gccattgaag gattgctgca ggaatcctca gtgggagggc aagggtgcct ccaacccctg
     1321 ctctactgga ctgctgctag gaggctggcc aaggtgacaa ctcaggagcc aggaggtagg
     1381 cattgccatc attttgtgat gctgtgaaaa atagaggagt ttctgttgtt ccttattaaa
     1441 caacaaaggt gaagattctt ttttgtttta ct
//
