LOCUS       NM_001107125            1535 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Rattus norvegicus mitochondrial rRNA methyltransferase 2 (Mrm2),
            mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001107125 XM_001073997 XM_221949
VERSION     NM_001107125.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1535)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 1535)
  AUTHORS   Lee,K.W. and Bogenhagen,D.F.
  TITLE     Assignment of 2'-O-methyltransferases to modification sites on the
            mammalian mitochondrial large subunit 16 S ribosomal RNA (rRNA)
  JOURNAL   J Biol Chem 289 (36), 24936-24942 (2014)
   PUBMED   25074936
REFERENCE   3  (bases 1 to 1535)
  AUTHORS   Ching,Y.P., Zhou,H.J., Yuan,J.G., Qiang,B.Q., Kung Hf,H.F. and
            Jin,D.Y.
  TITLE     Identification and characterization of FTSJ2, a novel human
            nucleolar protein homologous to bacterial ribosomal RNA
            methyltransferase
  JOURNAL   Genomics 79 (1), 2-6 (2002)
   PUBMED   11827451
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474012.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_221949.4, XM_001073997.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB790613.1, EV768778.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1535
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q11"
     gene            1..1535
                     /gene="Mrm2"
                     /gene_synonym="Ftsj2"
                     /note="mitochondrial rRNA methyltransferase 2"
                     /db_xref="GeneID:304323"
                     /db_xref="RGD:1305944"
     exon            1..50
                     /gene="Mrm2"
                     /gene_synonym="Ftsj2"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..783
                     /gene="Mrm2"
                     /gene_synonym="Ftsj2"
                     /EC_number="2.1.1.-"
                     /note="putative ribosomal RNA methyltransferase 2; FtsJ
                     homolog 2; FtsJ RNA methyltransferase homolog 2"
                     /codon_start=1
                     /product="rRNA methyltransferase 2, mitochondrial"
                     /protein_id="NP_001100595.1"
                     /db_xref="GeneID:304323"
                     /db_xref="RGD:1305944"
                     /translation="MTGYPKLVGVPLKVRRLHTAVCHYKGRTGAEHLWLMRHLKDPFV
                     KAAKAESYRCRSAFKLLEMNEKHHILRPGLRVLDCGAAPGAWSQVAVQSVNATGADSS
                     SPMGFVLGVDLLHMFPLAGATFLCPADVTDPRTFQRILELLPRRRADVILSDMAPNAT
                     GIRDLDHDRLISLCLTLVDMAVDILHPGGTLLCKTWAGSKSHLLQKRLAQEFRSTRVV
                     KPEASRKESAEVYLLATQYHGRKGSTKQ"
     exon            51..340
                     /gene="Mrm2"
                     /gene_synonym="Ftsj2"
                     /inference="alignment:Splign:2.1.0"
     exon            341..1535
                     /gene="Mrm2"
                     /gene_synonym="Ftsj2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgggacttc cggcggcggg aggaaaccgc cagcaatctg caatgactgg gtatccgaag
       61 ctggtaggcg ttccccttaa ggttcggagg ttacacacag cagtgtgtca ctacaagggc
      121 cggacaggcg ccgagcacct gtggttgatg cgccatctaa aggacccgtt tgtgaaggcc
      181 gcaaaggcgg agagttaccg ctgccgcagc gccttcaagc tcctggagat gaatgagaag
      241 catcacatcc tgaggcctgg gctccgggtg ctggactgcg gggcagctcc cggggcctgg
      301 agtcaggtgg cagtgcagag cgtcaacgcc acaggagcag attccagctc tcccatgggc
      361 ttcgtgctcg gggtcgatct tcttcacatg ttccctttgg caggagcaac ttttctgtgc
      421 cctgctgatg tgactgaccc cagaactttc cagagaattt tagaactgct tcccagaagg
      481 agagcggatg tgattctgag tgacatggca ccgaatgcca ctgggatccg agaccttgat
      541 catgacaggc tcataagctt gtgccttacc cttgtggaca tggctgtgga catcctgcac
      601 cccgggggga cactgctgtg taaaacctgg gccggaagta aaagccacct gctgcagaag
      661 agactagccc aggaattccg aagcacaagg gtcgtgaaac cggaggctag caggaaagag
      721 tccgcagagg tctatctgtt agccacacag taccatggga ggaagggctc caccaagcag
      781 tgattctgcc ccgcccttcc gggagcgcgt ctgtctggag cgtggatcca agctgagttg
      841 tggatatgaa cagcaccccg aggcactggg gtttaagaga ttaaaaaaaa ccgtattcaa
      901 ggactgtgaa cgagtgctaa gaatggggcg cacaatggct cagtgagaaa acggggcttg
      961 ctgacgccag tgcagtctct gggacccctg tagcagcaag agagaaccaa cccctgaaag
     1021 ttggtcctga ccccccacat gcgggggcgc gcacacacac acacacacac acacacacac
     1081 acacacacac acacacacac cgcacacaat ataaacaagt atattggcca tttgacacaa
     1141 acctacctat gtctgggaag aaagaatccg actgagggat tgcctctatc agctcggcct
     1201 gtgggtgagc atgtgagtct tgattactga ctgatggggg cggggcagcc ctgtgggggg
     1261 aggggtgcat tcctaggcag gtgagcctga gttgtatgag aaagcggggt gagcaagact
     1321 gaggaacaag ccagtaagca gcacccacac cccgcggtgg cggtctggtc tcccgttgaa
     1381 ttacagcctc caggttcccg ccctgagagc ccactttgat ctccttcggt gatggactgt
     1441 ggttgggatg agtgagccaa aggaaccctt tcctcccaag gcttttaagt gctggaagca
     1501 aaccacgatc tctattgtga ctttattttt ctggc
//
