LOCUS       NM_001108832            2418 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus mitochondrial rRNA methyltransferase 1 (Mrm1),
            mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001108832 XM_001081102 XM_017597426 XM_343950
VERSION     NM_001108832.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2418)
  AUTHORS   Lee,K.W. and Bogenhagen,D.F.
  TITLE     Assignment of 2'-O-methyltransferases to modification sites on the
            mammalian mitochondrial large subunit 16 S ribosomal RNA (rRNA)
  JOURNAL   J Biol Chem 289 (36), 24936-24942 (2014)
   PUBMED   25074936
REFERENCE   2  (bases 1 to 2418)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 2418)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On or before Apr 13, 2021 this sequence version replaced
            XM_017597426.2, NM_001108832.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643289.28854.1,
                                           SRR26643429.38112.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-678               JAXUCZ010000010.1  70193454-70194131   c
            679-772             JAXUCZ010000010.1  70193203-70193296   c
            773-905             JAXUCZ010000010.1  70190483-70190615   c
            906-1025            JAXUCZ010000010.1  70190282-70190401   c
            1026-2418           JAXUCZ010000010.1  70188748-70190140   c
FEATURES             Location/Qualifiers
     source          1..2418
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..2418
                     /gene="Mrm1"
                     /gene_synonym="RGD1566232"
                     /note="mitochondrial rRNA methyltransferase 1"
                     /db_xref="GeneID:363661"
                     /db_xref="RGD:1566232"
     exon            1..678
                     /gene="Mrm1"
                     /gene_synonym="RGD1566232"
                     /inference="alignment:Splign:2.1.0"
     CDS             143..1105
                     /gene="Mrm1"
                     /gene_synonym="RGD1566232"
                     /note="mitochondrial rRNA methyltransferase 1 homolog"
                     /codon_start=1
                     /product="rRNA methyltransferase 1, mitochondrial"
                     /protein_id="NP_001102302.1"
                     /db_xref="GeneID:363661"
                     /db_xref="RGD:1566232"
                     /translation="MLLLWTVGCFNRLVARHFSSVARPGERPGGEELSRLLLDDLAPA
                     QRLERLFGVSPCLLALRAARRHVARLLLQAGKAGLQGERAELLRVAEARGIPVLRPRR
                     QKLDALCGYQVHQGVCMEVSRLRPRPCDEAADTSSGDDPQQLWLVLEGIQDPRNLGAV
                     MRSAYFLGVDRVITSRRNSCPLTPVVSKASAGAMEVMDVFASPDLASFLQAKAQQGWL
                     VVGTVGCPGPEISQSSKVPVTSCLEFIWDRPTLLVLGNEGSGLSQGVFATCQLLLTIL
                     PGRHLPPGLESLNVSVATGILLHSICSQKKGFPVQERGQRLQDS"
     exon            679..772
                     /gene="Mrm1"
                     /gene_synonym="RGD1566232"
                     /inference="alignment:Splign:2.1.0"
     exon            773..905
                     /gene="Mrm1"
                     /gene_synonym="RGD1566232"
                     /inference="alignment:Splign:2.1.0"
     exon            906..1025
                     /gene="Mrm1"
                     /gene_synonym="RGD1566232"
                     /inference="alignment:Splign:2.1.0"
     exon            1026..2418
                     /gene="Mrm1"
                     /gene_synonym="RGD1566232"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggacccac gtgggagtct gggaggcgac tgtctaggct cgagtgtcag gtcgtgggca
       61 gtctttgagc ggggacgagg tgtgggaggc taacgtgttc tccccagcag tctgttacag
      121 agttccgggc gctgctggag caatgctact cctctggacg gtcggatgct tcaatcgcct
      181 cgttgcccgc catttctcct ccgtggctcg gcccggggag cggcctggcg gggaggagct
      241 gagtcgcttg cttcttgatg acctggcgcc agcccagagg ctggaacgtc tgtttggcgt
      301 gtccccatgc ctcctggcct tgcgggccgc ccgccggcac gtggcccggc tcctgctcca
      361 ggccggtaag gctggactgc agggggagcg ggccgagctg ctccgggtgg ccgaggctcg
      421 gggcatccct gtcttgaggc ccaggcggca gaaactggat gccttgtgtg gctaccaggt
      481 gcaccagggc gtgtgcatgg aggtcagccg gctgcgacct cggccttgcg atgaggcggc
      541 agacacgagc tcaggcgacg accctcagca actgtggctc gtccttgagg ggatccagga
      601 tccccgcaat cttggggctg tgatgcgctc cgcttacttc ctcggagtag acagggtcat
      661 caccagccgg agaaacagct gtccgcttac tccagtagtc agcaaggcca gcgctggggc
      721 catggaagtg atggacgtgt tcgcctctcc tgacctggcg agttttttgc aggccaaggc
      781 ccagcagggg tggctcgtgg tgggcacggt gggctgccca ggtcctgaga tctcccagtc
      841 ctccaaggtc cccgtcacta gctgcttaga gttcatctgg gaccggccca ctctcctggt
      901 gctgggcaat gagggctctg gtctgtccca gggggttttc gccacctgcc agctgctcct
      961 taccattctg cccggacgcc acctgcctcc cggccttgag tccttgaatg tgtctgtggc
     1021 tacaggaatt cttctacact ccatttgcag ccagaagaag ggtttccctg tacaggagag
     1081 aggacaacgt ctccaagact cctgagaacc cttagctacg tttgaaggac tcagagaggc
     1141 ccagtaccca ggactaccat cgtggtcaga aaaacagggc aaatgtgggc tgacatagac
     1201 tgtctgagat gagtcacaca ttcatcctca ggcttggatg taatggaccc tcgacttgtg
     1261 agatcctatt tgttggctac agtcaggaga ctttaaagac caaaagaagt ttcatttcca
     1321 gttggaaatg gtagtttgct aattcccagg acggattagg acagacagta tctgtcttgg
     1381 ctcctgctag aagtcaggag gctgccgtgg caggcggagg aaccacgcag tccagtgcag
     1441 ggtgtgtgga atgtgagggt gagtttgttg agggaagctg agtgaacagg tacataatag
     1501 ccctatctct cagagtgatg gggataagac tccagattcc atccactgag cccttagcag
     1561 ctgagtggtc atgcccaatc tctccagtag gtggcagtct tgctctttgc accatagttt
     1621 tgcagcccct tgcagggaga cccctctctg cagggaccca ttagagacag ggaaaatagc
     1681 caacagcttc cagacactgg ccagtgcagc ccagtggagg gaacctatga tcccaggcct
     1741 ttgttgcttt tgagtctgag aggctgtgaa gtcagggtca cttttgtgca acccactagg
     1801 cttggacccc tcctccagcg tcccacaagt ggagcagaag tgatattacc gagcagtggt
     1861 ctcactctgg gctacacatt ggaacaccta ataagcttta aagaaactag gccaaaacag
     1921 cagctgctgt gtgctgctgg gaagggagac cgggtctaat gttctgtgta cctttggtgt
     1981 cctcaaactt gttatttaac tgaggatttc cttgaacttt tgatcttctt acaccacgat
     2041 ggccaatgta tacgttgctg gggatagacc ccagagcttc atgcaagcac agcattcacc
     2101 ccacccagcg agctgtatct gagccctggg ctggacagtt ctttgctgta ggtaccgtcc
     2161 tgggcgttgt gagatgccat cctcccgatg acagggagtc tataccatct cttgtcacaa
     2221 aaccaaaact gtctccacac agggccagat catctctgac cgacagccct gagtgtgggg
     2281 tgggaggaca tcgacccttg aattgtaacc ctggaggctg tgagagcggg gatgagttgc
     2341 ctccaggcct tctctgtatc ctcgaaggat gtatgtagta ggtgctcgat aaacaaacaa
     2401 acagcccctt cccctgta
//
