LOCUS       NM_145787               1313 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus MAS related GPR family member X3 (Mrgprx3), mRNA.
ACCESSION   NM_145787 NM_001002282
VERSION     NM_145787.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Chen,Y.F., Tian,E.Q., Wang,G.P., Zhou,F. and Zhang,L.C.
  TITLE     [The distribution of Mas-related G protein-coupled receptor A in
            cerebrospinal fluid-contacting nucleus of normal rats and its
            up-regulation in neuropathic pain]
  JOURNAL   Sheng Li Xue Bao 74 (3), 353-358 (2022)
   PUBMED   35770633
  REMARK    GeneRIF: [The distribution of Mas-related G protein-coupled
            receptor A in cerebrospinal fluid-contacting nucleus of normal rats
            and its up-regulation in neuropathic pain].
REFERENCE   2  (bases 1 to 1313)
  AUTHORS   Premzl,M.
  TITLE     Comparative genomic analysis of eutherian Mas-related G
            protein-coupled receptor genes
  JOURNAL   Gene 540 (1), 16-19 (2014)
   PUBMED   24583173
REFERENCE   3  (bases 1 to 1313)
  AUTHORS   Heo,J., Vaidehi,N., Wendel,J. and Goddard,W.A. 3rd.
  TITLE     Prediction of the 3-D structure of rat MrgA G protein-coupled
            receptor and identification of its binding site
  JOURNAL   J Mol Graph Model 26 (4), 800-812 (2007)
   PUBMED   17728165
  REMARK    GeneRIF: Results validate the predicted structure for MrgA and
            should be useful for seeking other small molecule agonists and
            antagonists.
REFERENCE   4  (bases 1 to 1313)
  AUTHORS   Gorzalka,S., Vittori,S., Volpini,R., Cristalli,G., von Kugelgen,I.
            and Muller,C.E.
  TITLE     Evidence for the functional expression and pharmacological
            characterization of adenine receptors in native cells and tissues
  JOURNAL   Mol Pharmacol 67 (3), 955-964 (2005)
   PUBMED   15604413
  REMARK    GeneRIF: Kinetics of adenine binding to the adenine receptor of the
            rat brain cortex.
REFERENCE   5  (bases 1 to 1313)
  AUTHORS   Zylka,M.J., Dong,X., Southwell,A.L. and Anderson,D.J.
  TITLE     Atypical expansion in mice of the sensory neuron-specific Mrg G
            protein-coupled receptor family
  JOURNAL   Proc Natl Acad Sci U S A 100 (17), 10043-10048 (2003)
   PUBMED   12909716
REFERENCE   6  (bases 1 to 1313)
  AUTHORS   Bender,E., Buist,A., Jurzak,M., Langlois,X., Baggerman,G.,
            Verhasselt,P., Ercken,M., Guo,H.Q., Wintmolders,C., Van den
            Wyngaert,I., Van Oers,I., Schoofs,L. and Luyten,W.
  TITLE     Characterization of an orphan G protein-coupled receptor localized
            in the dorsal root ganglia reveals adenine as a signaling molecule
  JOURNAL   Proc Natl Acad Sci U S A 99 (13), 8573-8578 (2002)
   PUBMED   12084918
REFERENCE   7  (bases 1 to 1313)
  AUTHORS   Dong,X., Han,S., Zylka,M.J., Simon,M.I. and Anderson,D.J.
  TITLE     A diverse family of GPCRs expressed in specific subsets of
            nociceptive sensory neurons
  JOURNAL   Cell 106 (5), 619-632 (2001)
   PUBMED   11551509
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC089774.1.
            
            On or before Nov 4, 2005 this sequence version replaced
            NM_001002282.1, NM_145787.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089774.1, CO565764.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN13663605, SAMN14984024
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..1313
                     /gene="Mrgprx3"
                     /gene_synonym="Mgrg1; MrgA; Mrga10; Mrgpra"
                     /note="MAS related GPR family member X3"
                     /db_xref="GeneID:252960"
                     /db_xref="RGD:632282"
     exon            1..65
                     /gene="Mrgprx3"
                     /gene_synonym="Mgrg1; MrgA; Mrga10; Mrgpra"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..1050
                     /gene="Mrgprx3"
                     /gene_synonym="Mgrg1; MrgA; Mrga10; Mrgpra"
                     /note="adenine receptor; Mas-related gene A; Mas-related G
                     protein-coupled receptor g1; MAS-related G-protein coupled
                     receptor, member A; G-protein coupled receptor; rc 56.1.3;
                     nuclear receptor MrgA10 RF-amide G protein-coupled
                     receptor; MAS-related GPR, member X3"
                     /codon_start=1
                     /product="mas-related G-protein coupled receptor member A"
                     /protein_id="NP_665730.2"
                     /db_xref="GeneID:252960"
                     /db_xref="RGD:632282"
                     /translation="MGESFTGTGFINLNTSASTIAVTTTNPMDKTIPGSFNSRTLIPN
                     LLIIISGLVGLIGNAMVFWLLGFRLARNAFSVYILNLALADFLFLLCHIIDSTLLLLK
                     FSYPNIIFLPCFNTVMMVPYIAGLSMLSAISTERCLSVVCPIWYRCRRPKHTSTVMCS
                     AIWVLSLLICILNRYFCGFLDTKYEKDNRCLASNFFTAACLIFLFVVLCLSSLALLVR
                     LFCGAGRMKLTRLYATIMLTVLVFLLCGLPFGIHWFLLIWIKIDYGKFAYGLYLAALV
                     LTAVNSCANPIIYFFVGSFRHQKHQTLKMVLQRALQDTPETAENTVEMSSSKVEP"
     exon            66..1287
                     /gene="Mrgprx3"
                     /gene_synonym="Mgrg1; MrgA; Mrga10; Mrgpra"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgtgactgta tctttccttc tacgcaagcc agcttgctac atccagcaag aagaatgggg
       61 gaaagcttca ccggtacagg gtttataaac ctaaacacct cagcctcgac aatagcagtc
      121 acaacaacaa atccaatgga caaaaccata cctggaagtt tcaacagcag gaccctgatc
      181 ccaaatttgt tgatcatcat ctcgggactg gtcgggctga taggaaacgc catggtgttc
      241 tggctcctgg gcttccgctt agccaggaat gccttctcag tctacatcct aaacttggcc
      301 ctggctgact tcctcttcct cctctgtcac atcatagatt ccacgctgct ccttctcaag
      361 ttttcctacc ccaacattat ctttctccca tgctttaaca ccgtcatgat ggtcccctac
      421 atcgcaggcc tgagcatgct cagtgccatc agcaccgagc gctgcctgtc tgttgtgtgc
      481 cccatctggt atcgctgccg ccgcccaaaa cacacttcaa ctgtcatgtg ctctgcgatc
      541 tgggtcctgt cactgttgat ctgcattctg aataggtatt tctgtggctt cttagatacc
      601 aaatacgaaa aggacaaccg gtgtctggca tcgaacttct ttactgccgc gtgcctgata
      661 tttttgtttg tagtcctctg tctgtccagt ctggctctgc tggtcagatt gttctgtggc
      721 gctgggcgga tgaagctcac cagattgtac gcgaccatca tgctgaccgt tttggttttt
      781 ctcctctgcg ggttgccctt tggcatccac tggttcctgt taatctggat taagattgat
      841 tatggtaaat ttgcttacgg tctttacctg gcggcactcg tcctgactgc tgttaacagc
      901 tgtgccaacc ccatcattta cttcttcgtg ggctccttca ggcatcagaa gcaccagacc
      961 ctcaaaatgg ttctccagag ggcgctgcag gacacccctg agacagcgga aaacacggtg
     1021 gagatgtcaa gcagcaaggt ggagccgtga tgaagggcct ctgcctggac ctcagaggtg
     1081 gctttggcgt gagcactgcc ctgctgcact tgaccactgt ccactctcct ctcagtcttg
     1141 ggcctcgaca tgcctcagtg atccaccatc cgcagctctc cattgacttg gttttccaac
     1201 ctctcctgag taaaagcatt aatcagaaag tatggagtct ccatccttct tgacgtaaat
     1261 aaaagtctca tgctaacttc ctctgaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//
