LOCUS       NM_001002280             885 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus MAS related GPR family member X2 (Mrgprx2), mRNA.
ACCESSION   NM_001002280 XM_218596
VERSION     NM_001002280.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 885)
  AUTHORS   McNeil,B.D., Pundir,P., Meeker,S., Han,L., Undem,B.J., Kulka,M. and
            Dong,X.
  TITLE     Identification of a mast-cell-specific receptor crucial for
            pseudo-allergic drug reactions
  JOURNAL   Nature 519 (7542), 237-241 (2015)
   PUBMED   25517090
REFERENCE   2  (bases 1 to 885)
  AUTHORS   Premzl,M.
  TITLE     Comparative genomic analysis of eutherian Mas-related G
            protein-coupled receptor genes
  JOURNAL   Gene 540 (1), 16-19 (2014)
   PUBMED   24583173
REFERENCE   3  (bases 1 to 885)
  AUTHORS   Zhang,X., Bedigian,A.V., Wang,W. and Eggert,U.S.
  TITLE     G protein-coupled receptors participate in cytokinesis
  JOURNAL   Cytoskeleton (Hoboken) 69 (10), 810-818 (2012)
   PUBMED   22888021
REFERENCE   4  (bases 1 to 885)
  AUTHORS   Subramanian,H., Gupta,K., Guo,Q., Price,R. and Ali,H.
  TITLE     Mas-related gene X2 (MrgX2) is a novel G protein-coupled receptor
            for the antimicrobial peptide LL-37 in human mast cells: resistance
            to receptor phosphorylation, desensitization, and internalization
  JOURNAL   J Biol Chem 286 (52), 44739-44749 (2011)
   PUBMED   22069323
REFERENCE   5  (bases 1 to 885)
  AUTHORS   Robas,N., Mead,E. and Fidock,M.
  TITLE     MrgX2 is a high potency cortistatin receptor expressed in dorsal
            root ganglion
  JOURNAL   J Biol Chem 278 (45), 44400-44404 (2003)
   PUBMED   12915402
REFERENCE   6  (bases 1 to 885)
  AUTHORS   Zylka,M.J., Dong,X., Southwell,A.L. and Anderson,D.J.
  TITLE     Atypical expansion in mice of the sensory neuron-specific Mrg G
            protein-coupled receptor family
  JOURNAL   Proc Natl Acad Sci U S A 100 (17), 10043-10048 (2003)
   PUBMED   12909716
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF518239.1.
            
            On Apr 19, 2005 this sequence version replaced XM_218596.3.
FEATURES             Location/Qualifiers
     source          1..885
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..885
                     /gene="Mrgprx2"
                     /gene_synonym="Mgrg6; MrgB1; Mrgprb1"
                     /note="MAS related GPR family member X2"
                     /db_xref="GeneID:404640"
                     /db_xref="RGD:738048"
     CDS             1..885
                     /gene="Mrgprx2"
                     /gene_synonym="Mgrg6; MrgB1; Mrgprb1"
                     /note="MAS-related G protein-coupled receptor, member B1;
                     MAS-related gene B1; Mas-related G protein-coupled
                     receptor g6; MAS-related GPR, member X2"
                     /codon_start=1
                     /product="mas-related G-protein coupled receptor member
                     X2"
                     /protein_id="NP_001002280.1"
                     /db_xref="GeneID:404640"
                     /db_xref="RGD:738048"
                     /translation="MSFCEVVSCAIILLSLIIALVGLVGNGTVFWLLGFQMRRNAFSV
                     YILNLAGADFLFMCFQIVYCSHIMLDMYYIPIKFPLFSIVVLNIGYLCGMSILSAISI
                     ERCLSVMWPIWYRCQRPRHTSAVICTLLWVLALVWSLIEGKECGFLFDTNGPGWCETF
                     DLIATAWLIVLIVVLLGSSLALVINIFCGLYRIPVTRLYVTIVFTVLVFLLCGLPYGI
                     YWFLLEWTEKFNYNLPCGFHPVTVLLSCVNSCANPIIYFLVGSIRHHRFQRKTLKLLL
                     QKAMQDTPEEEECGEMGS"
     exon            1..885
                     /gene="Mrgprx2"
                     /gene_synonym="Mgrg6; MrgB1; Mrgprb1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtcatttt gtgaagttgt atcttgtgcc ataattttgc tttctctcat cattgcccta
       61 gttgggcttg ttggaaatgg aacagtgttt tggctcctgg gcttccagat gcgcagaaat
      121 gccttttcag tctacatcct caacctggct ggtgctgatt ttctcttcat gtgcttccaa
      181 attgtttatt gttctcatat catgttggac atgtactaca tccctatcaa atttcccctg
      241 ttttcaattg ttgtgttaaa cattggttat ctttgtggca tgagcatcct cagtgccatt
      301 agcattgaac gctgcctatc tgtcatgtgg cccatctggt atcgctgcca acgcccaagg
      361 cacacatcag ctgtcatatg taccttgctt tgggtcttgg ccctagtgtg gagcctcata
      421 gaaggaaagg aatgtggctt tctatttgat accaatggcc ctggttggtg tgagacattt
      481 gatttaattg ctactgcatg gctaattgtt ttaattgtgg ttctcctggg gtccagtcta
      541 gccttagtga ttaatatctt ctgtggctta tacaggattc ctgtgaccag gctgtatgtg
      601 accattgtgt tcacagtgct ggtcttcctg ctctgtggtc tgccctatgg gatctactgg
      661 ttcctcttag aatggaccga gaaatttaat tataacttac cttgtggttt tcatcccgtg
      721 acagtacttc tatcctgtgt taacagctgt gccaacccta tcatttactt ccttgttggc
      781 tctattaggc accacaggtt ccaacgcaag actctcaagc tacttttgca gaaagccatg
      841 caagacactc ctgaagaaga agaatgtgga gagatgggct cctga
//
