LOCUS       NM_001408774            2023 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus MAS-related GPR, member B2 (Mrgprb2), mRNA.
ACCESSION   NM_001408774 XM_039096228
VERSION     NM_001408774.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2023)
  AUTHORS   Heller,D., Doyle,J.R., Raman,V.S., Beinborn,M., Kumar,K. and
            Kopin,A.S.
  TITLE     Novel Probes Establish Mas-Related G Protein-Coupled Receptor X1
            Variants as Receptors with Loss or Gain of Function
  JOURNAL   J Pharmacol Exp Ther 356 (2), 276-283 (2016)
   PUBMED   26582731
REFERENCE   2  (bases 1 to 2023)
  AUTHORS   Premzl,M.
  TITLE     Comparative genomic analysis of eutherian Mas-related G
            protein-coupled receptor genes
  JOURNAL   Gene 540 (1), 16-19 (2014)
   PUBMED   24583173
REFERENCE   3  (bases 1 to 2023)
  AUTHORS   Liu,Q., Tang,Z., Surdenikova,L., Kim,S., Patel,K.N., Kim,A., Ru,F.,
            Guan,Y., Weng,H.J., Geng,Y., Undem,B.J., Kollarik,M., Chen,Z.F.,
            Anderson,D.J. and Dong,X.
  TITLE     Sensory neuron-specific GPCR Mrgprs are itch receptors mediating
            chloroquine-induced pruritus
  JOURNAL   Cell 139 (7), 1353-1365 (2009)
   PUBMED   20004959
REFERENCE   4  (bases 1 to 2023)
  AUTHORS   Zylka,M.J., Dong,X., Southwell,A.L. and Anderson,D.J.
  TITLE     Atypical expansion in mice of the sensory neuron-specific Mrg G
            protein-coupled receptor family
  JOURNAL   Proc Natl Acad Sci U S A 100 (17), 10043-10048 (2003)
   PUBMED   12909716
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jun 24, 2022 this sequence version replaced XM_039096228.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2023              JAXUCZ010000001.1  107537410-107539432 c
FEATURES             Location/Qualifiers
     source          1..2023
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..2023
                     /gene="Mrgprb2"
                     /gene_synonym="Mgrg10; MrgB6; Mrgprb6; Mrgprx1"
                     /note="MAS-related GPR, member B2"
                     /db_xref="GeneID:502338"
                     /db_xref="RGD:1591915"
     exon            1..2023
                     /gene="Mrgprb2"
                     /gene_synonym="Mgrg10; MrgB6; Mrgprb6; Mrgprx1"
                     /inference="alignment:Splign:2.1.0"
     CDS             1..939
                     /gene="Mrgprb2"
                     /gene_synonym="Mgrg10; MrgB6; Mrgprb6; Mrgprx1"
                     /note="MAS-related G protein-coupled receptor, member B6;
                     Mas-related G protein-coupled receptor g10; MAS related
                     GPR family member X1; MAS-related GPR, member X1;
                     MAS-related gene B6; mas-related G-protein coupled
                     receptor member B2"
                     /codon_start=1
                     /product="MAS-related GPR, member B2"
                     /protein_id="NP_001395703.1"
                     /db_xref="GeneID:502338"
                     /db_xref="RGD:1591915"
                     /translation="MDINISTLDIDIIELNGSNYTNTEICFVKIQVMSLLSLIICPVG
                     MVLNAIVLWFLGFQMTRNAFSVYILNLAGADFFFLYSQFLFYILAIISYKYSISFRIP
                     FLFEVLAKVAYLSGLSILSTISIERCLCIMWPIWYRCQRPRHTSSVTCFLLWTLSLLF
                     ALLEGAECGLLFNSFDQSRCLRFDLIFCAWSIVLFVVLCGSSLILLIRIFCGSQRIPV
                     TRLYVTIVLTVLFFLICCLPFGISWLIQWSRTLEYVGVCDYFHEGLFLSSINSCANPI
                     VYFLVGFIRQRKFQQKTLKLLLQRAMEEECEDRGPS"
ORIGIN      
        1 atggatataa acatctcaac tctggatatt gacatcatag aactgaacgg aagcaactac
       61 actaatactg agatatgttt tgtcaagatc caagtcatga gtttactttc cctcatcatt
      121 tgccctgttg ggatggtgct aaatgccata gtgctgtggt tcctgggctt ccagatgacc
      181 aggaatgcct tctctgtcta tatcctcaac ctggctgggg ctgacttttt cttcctgtac
      241 tctcagtttt tattttacat tcttgctatc atttcctaca agtactccat ttctttccgg
      301 atccctttcc tttttgaagt gttggcaaaa gttgcttatc tttctggcct gagcattctt
      361 agcaccatca gcattgaacg ctgcctgtgt atcatgtggc ccatctggta tcgctgccaa
      421 cgaccaagac acacatcatc ggtcacctgt ttcttgcttt ggactttgtc cttgttgttt
      481 gctcttctgg agggggcaga atgtggcttg ctgtttaaca gttttgacca gtctcggtgt
      541 ttgagatttg atttaatctt ttgcgcatgg tcaattgttt tatttgtggt tctctgtggg
      601 tccagcctca tcctacttat caggatcttc tgtggctccc agcggatacc tgtgaccaga
      661 ctgtatgtga ccattgtact cacagtgcta ttcttcctga tctgctgtct tccctttgga
      721 atctcctggc tcatccaatg gagtagaact ttggaatatg ttggggtttg tgattatttt
      781 cacgagggac tatttttatc ctcgattaac agctgcgcca accctatcgt ttacttcctg
      841 gttggcttta ttcgtcagcg caagttccaa cagaagactc tgaagctgct tcttcagaga
      901 gcaatggaag aagagtgtga agacaggggt ccttcctgaa atccagaaga actgggaaca
      961 gcctagcatg gcatctgcga gctgctttga tcagacagaa acggagtttt agagaaaaat
     1021 gtttttctct gtgagccatt ttcacaattt tattcagctt gttacctgat cttcagtcag
     1081 ttaaaaaaat aatcactttt tttgtgaaag ttgatagata taagacttgt catacaaata
     1141 ctgactgcag tattttttgg agctgtgttg ctcaggcttc atcaactcct cttgatggga
     1201 ctccatgtaa gtgttctggg gttgaggaga tctgttgatt actatgaaca aatcccacat
     1261 tcacctaaag gctaaaggtc ctgcagagaa gagctgcatt tctttagtta ctgaaattta
     1321 tagtgtaaaa caaataatag attctgtaaa aattctctgt ccatttggaa tgactccatt
     1381 gttgtatttt ttttgtttca agagttaaat agatgtactc tataatccta atgtttatta
     1441 atttctccag attataaaga atatatagag tgatggtctt ccttatataa attgcttggt
     1501 aaacaaatat atgctcttaa gagaagtcta ttaaatctct attaccacag tagtaccctc
     1561 accttcaagt tcattgtgtc tttcattttt ggcattggaa gagtgcagta aggttttgta
     1621 atgagatctg tcaacatcta tgcacatatg aagatgttct ctgtggcttg ctttacaata
     1681 tcctgcttat tggcctatgg tccagccttt tttctttctt cttgcattgc cttgattgcc
     1741 tttctctctg tcaattactc atgataaatt atatatatat atgtatatgt gtatgtatgt
     1801 atatatatat gatattttct ttatttacat ttcaaatgtt atcccctttc ccagtttccc
     1861 ctccagaaaa tcgccatccc atcactctac cccctgcctc catgagggtg ttcctccact
     1921 caccctccta ctcactccct cccacctacc ctccctggca ttcgccctac atgggcatag
     1981 agccttcaca ggaccaaggg cctctcctcc cattgatacc caa
//
