LOCUS       NM_001402078            3039 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus MPV17 mitochondrial inner membrane protein like
            (Mpv17l), transcript variant 1, mRNA.
ACCESSION   NM_001402078 XM_008767466
VERSION     NM_001402078.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3039)
  AUTHORS   Iida,R., Ueki,M. and Yasuda,T.
  TITLE     Identification of Rhit as a novel transcriptional repressor of
            human Mpv17-like protein with a mitigating effect on mitochondrial
            dysfunction, and its transcriptional regulation by FOXD3 and GABP
  JOURNAL   Free Radic Biol Med 52 (8), 1413-1422 (2012)
   PUBMED   22306510
REFERENCE   2  (bases 1 to 3039)
  AUTHORS   Ghosh,D. and Berg,J.M.
  TITLE     A proteome-wide perspective on peroxisome targeting signal
            1(PTS1)-Pex5p affinities
  JOURNAL   J Am Chem Soc 132 (11), 3973-3979 (2010)
   PUBMED   20178365
REFERENCE   3  (bases 1 to 3039)
  AUTHORS   Iida,R., Yasuda,T., Tsubota,E., Takatsuka,H., Matsuki,T. and
            Kishi,K.
  TITLE     Human Mpv17-like protein is localized in peroxisomes and regulates
            expression of antioxidant enzymes
  JOURNAL   Biochem Biophys Res Commun 344 (3), 948-954 (2006)
   PUBMED   16631601
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Mar 5, 2022 this sequence version replaced XM_008767466.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.1949012.1,
                                           SRR26360172.566090.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-329               JAXUCZ010000010.1  2514427-2514755     c
            330-400             JAXUCZ010000010.1  2510995-2511065     c
            401-430             JAXUCZ010000010.1  2498383-2498412     c
            431-3039            JAXUCZ010000010.1  2495607-2498215     c
FEATURES             Location/Qualifiers
     source          1..3039
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q11"
     gene            1..3039
                     /gene="Mpv17l"
                     /note="MPV17 mitochondrial inner membrane protein like"
                     /db_xref="GeneID:100362572"
                     /db_xref="RGD:2324483"
     exon            1..329
                     /gene="Mpv17l"
                     /inference="alignment:Splign:2.1.0"
     CDS             20..604
                     /gene="Mpv17l"
                     /note="isoform 1 is encoded by transcript variant 1; MPV17
                     mitochondrial membrane protein-like; Mpv17 transgene,
                     kidney disease mutant-like (predicted)-like"
                     /codon_start=1
                     /product="mpv17-like protein isoform 1"
                     /protein_id="NP_001389007.1"
                     /db_xref="GeneID:100362572"
                     /db_xref="RGD:2324483"
                     /translation="MANWWRAFPRAARRYPWPTNVLLYAGLFSAGDALQQRLRGGPAD
                     WRQTRRVATLALTFHGNFNYMWLRLLERALPGRAPRTVLAKVLCDQTVGGPVALSAFY
                     VGMSILQGKDDIFLDLRQKFWNTYKTGLMYWPFVQLTNFSLVPVNWRTAYTGLCGFLW
                     ATFLCFSQQSGDGTVESIFILLRRKEAGDRSPEK"
     exon            330..400
                     /gene="Mpv17l"
                     /inference="alignment:Splign:2.1.0"
     exon            401..430
                     /gene="Mpv17l"
                     /inference="alignment:Splign:2.1.0"
     exon            431..3039
                     /gene="Mpv17l"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagggtaccc gggacgggta tggcgaactg gtggcgcgcg tttccacggg cggcgcggcg
       61 ctatccgtgg cccactaacg tgctgctcta cgccgggctc ttctcagccg gtgatgctct
      121 gcagcagcga ctaaggggcg gcccagccga ttggcgccag acgcggcgag tggccactct
      181 ggccctgact ttccacggaa acttcaacta catgtggctg cgcctgttgg agcgcgcgct
      241 gccaggccgc gcgccgcgca cagtcctggc caaggtgcta tgcgatcaga ctgtcggagg
      301 gccagtagcc ctctctgcct tctacgtcgg tatgagcatt ctccagggaa aggatgacat
      361 atttttggac ctgaggcaga aattctggaa tacatataag actggtctga tgtactggcc
      421 ttttgtgcag ctgaccaact tcagccttgt ccctgtgaac tggaggacag catacacggg
      481 actttgtggt ttcctctggg ccaccttcct ctgcttttca cagcagagcg gtgatggtac
      541 agtggagtcc atattcatcc tccttcgaag gaaggaggca ggtgacaggt ccccagagaa
      601 gtgaggtgtc caggactccc ttcctaggac gcagttctat ctctccatcg ctctcaatca
      661 tctgcaacaa gctttcttca ttgaccaatt gtggactcca tcatgaagaa ttactattcc
      721 atagggccac ttgatttgaa attatcaatg attattttaa cttttatcca agcctttccc
      781 agtcaatcca gtctgaaaag tcttattctc tggtattttc acttctttaa tgctttggtt
      841 aaaaactaca acaatggcat gtaacatttg agaatcatta atagttctaa tagccaattg
      901 aatttaaaaa aaaaaaaaac ctccagtttt ggttgtattt ttaacccaaa ctctcaggct
      961 atttcctaca tactttggaa tcggattgcc ttttgttctt atagtaaatt tttatgtata
     1021 taaaattcag tcaagaaggt tgaataatca gtccccctat gtattattat gccaacacta
     1081 aaattctgta agtagatgtt tttaatcttc aaaagggaat agtattggat atattctgta
     1141 tagaatattt tattgatact gcctactttt ttaaaaagaa ggttctctct ttgtgtagct
     1201 caggctggaa ctcactgtga accccagtga agcctcatct ctccaagtgc cgagattaca
     1261 ggcatgaacc attatatctt cctcttttga ttttatattg cagcacccaa gcacaggttt
     1321 ttaaaatcga tgtcttttag ctttgagaag atacaattga ccaaataccc aatgggacat
     1381 ttgatttctg aatgaaattt ctagaaaact aatcatttct ttcctctcta atgaagaagt
     1441 ctaatctgta ctagactagt gtacacagtt tgtagcagcc ctcttgcctc cacattctaa
     1501 atattgagat tacagtcatg agtcaccatg cttaaccagg gtcttacaca gactagtgct
     1561 ctgccactga ctgaattctg ggatcctgat agtagtcttt tataattcag tgctttaaaa
     1621 ttctttatct ttatacttca aagtggacac agcaatcatc agccagtttc ccacatttgt
     1681 tcagttagtc taatctcagc cagccacctt caggtttcag aatcatgcaa ataaccaggc
     1741 ctggacatgt gtgcctgtct actcagaaag ctaatggagg gcgatcattt tcgccaagga
     1801 gttcaagact gggctggaaa aaatagcaag tttctgcctc aaaaccacaa aaataaaaga
     1861 ttcaaaagta tgagtgtctt aagaaatttc agggctggag agatagctca gcggttaaga
     1921 gcactgactg ctcttcctga ggtcctgagt tcaattccca gcaaccacat ggtggctcac
     1981 aaccatctgt aatgagatct ggtgccctct tctggcctgc aggcgtacat gcaggcagaa
     2041 cactacacgt aatgaataaa ttaatcttaa aataaatttc agccatctca cctaaaaatt
     2101 gtctccatgt ctctattcct tctactggca tatatgacaa atttcaagat gtgaaatact
     2161 gaatgtataa ggtcagtttt ataattcatg tttaaatttc taagcaatta attaattgtt
     2221 tgtaatatgt ataaattata agcatgcacc atctaaaagg gtataaatta tggaatgtaa
     2281 tagaaattat tggggtggta tgaaagtata tccctgtatt ttcacttgtt aattgctatt
     2341 ccctgttact tgctggcagg atttggatat tgtcattttt atggcccatc accagttttc
     2401 tatatgttaa ttgtttgtcc ttcccaccac cccagaaaga ttttctgaga ctatcatatt
     2461 aaaaggcaag ctgccatggt gaaggtcaag cagtcctcag tgccaaaggg caaccctaag
     2521 agattgattg ggcgctgtcc tgctactgat tggttcaagc tggaatgtgg ctttttgatt
     2581 gataaagagc tgaccgctgg agctggggca ggaagtatgg agcataactt cagagatgca
     2641 ggagacttgg gcagatccaa ggggacttgg aaggaggcag aagggaagaa ggcggcagaa
     2701 gagagctgga aggagctgga agcatgaagt gagaaccaca tggagagatg ctgtggtggt
     2761 ttgcccatgg gaagtggcac tattaggagg tatggcttgt tagaggaagt gagtcactgt
     2821 ggagatgggc tttgaggtcc tatgctcaag ctctgacctg tgaggagagt ccctcctcct
     2881 ggctgccttg ggagagagtc ccctcttgtc tgccttcaaa aaagatttag aactctcagc
     2941 tccttctcca gtaccatgtc tggatgctgc catgttcccc accttgatga taatggactg
     3001 aaactgtaag ccagcaaaca ttaaacgtcc tttataaaa
//
