LOCUS       NM_001037642             801 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus mucosal pentraxin 1 (Mptx1), mRNA.
ACCESSION   NM_001037642
VERSION     NM_001037642.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 801)
  AUTHORS   Drew,J.E., Farquharson,A.J., Keijer,J. and Barrera,L.N.
  TITLE     Complex regulation of mucosal pentraxin (Mptx) revealed by discrete
            micro-anatomical locations in colon
  JOURNAL   Biochim Biophys Acta 1762 (9), 844-848 (2006)
   PUBMED   16978845
  REMARK    GeneRIF: This study demonstrates that consideration of regional
            differences in Mptx gene expression and micro-anatomical location
            is necessary in the interpretation and deciphering of its
            regulation in colon.
REFERENCE   2  (bases 1 to 801)
  AUTHORS   van der Meer-van Kraaij,C., Kramer,E., Jonker-Termont,D.,
            Katan,M.B., van der Meer,R. and Keijer,J.
  TITLE     Differential gene expression in rat colon by dietary heme and
            calcium
  JOURNAL   Carcinogenesis 26 (1), 73-79 (2005)
   PUBMED   15539406
  REMARK    GeneRIF: Mptx expression is restricted to the intestine, related to
            colonic cell turnover, and that Mptx might be a marker for
            diet-modulated mucosal integrity
REFERENCE   3  (bases 1 to 801)
  AUTHORS   Van Der Meer-Van Kraaij,C., Van Lieshout,E.M., Kramer,E., Van Der
            Meer,R. and Keijer,J.
  TITLE     Mucosal pentraxin (Mptx), a novel rat gene 10-fold down-regulated
            in colon by dietary heme
  JOURNAL   FASEB J 17 (10), 1277-1285 (2003)
   PUBMED   12832292
  REMARK    GeneRIF: Mucosal pentraxin (Mptx) is down-regulated in colon by
            dietary heme (Mptx).
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Oct 17, 2022 this sequence version replaced NM_001037642.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY426671.1, SRR26643291.34453.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMN06680423
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-118               JAXUCZ010000013.1  88263752-88263869   c
            119-801             JAXUCZ010000013.1  88260335-88261017   c
FEATURES             Location/Qualifiers
     source          1..801
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q24"
     gene            1..801
                     /gene="Mptx1"
                     /gene_synonym="Mptx"
                     /note="mucosal pentraxin 1"
                     /db_xref="GeneID:289243"
                     /db_xref="RGD:1590926"
     exon            1..118
                     /gene="Mptx1"
                     /gene_synonym="Mptx"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..714
                     /gene="Mptx1"
                     /gene_synonym="Mptx"
                     /codon_start=1
                     /product="mucosal pentraxin precursor"
                     /protein_id="NP_001032731.1"
                     /db_xref="GeneID:289243"
                     /db_xref="RGD:1590926"
                     /translation="MEKLIVGTLLLTVLSGGISQSDMDGKAFIFPQESSTAYVSLIPR
                     VKKSLQNFTLCLKAFTDLTRPYSIFSYNTKTQDNEILLFVQNSGEYMFYVGNSAAIFK
                     APTSLYDPVHICVNWESASGIAEFWLNGKPLGRKGLKKGYTVGGEAKIIIGQEQDSFG
                     GNFDAKQSFVGEIWDVSLWDHVIPLEEAHDSCDGGNLINFRALTYEENGYVVTKPKLW
                     T"
     exon            119..801
                     /gene="Mptx1"
                     /gene_synonym="Mptx"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acagaagcaa gtgttgctga tctcccacta ctgaaggtgt ccaagaagaa cacaatggag
       61 aagcttattg tcggcaccct gcttctcact gttctttcag gaggtatatc acaatcagac
      121 atggatggca aggcattcat tttccctcaa gaatcgtcca ctgcctatgt gtccctgata
      181 cctcgggtga agaagtcact gcaaaacttc accctgtgtc tgaaggcctt cacagacctg
      241 acccgccctt acagcatctt ctcctacaac acaaaaactc aggacaatga gattcttctc
      301 tttgtgcaaa atagtggaga atacatgttc tatgttggga attcggctgc cattttcaag
      361 gcacccacaa gtctttatga tccagtccat atctgtgtga actgggagtc tgcctctggg
      421 attgcagaat tctggctaaa tggaaagccg ttggggagga aaggcttgaa gaaggggtac
      481 actgtgggag gtgaggcaaa gatcattata ggacaagagc aggattcctt tgggggaaat
      541 tttgatgcaa agcaatcttt cgttggggag atatgggatg tttccttatg ggaccatgtg
      601 atccccctag aagaggcaca tgacagctgt gatggtggca accttataaa cttccgagct
      661 cttacttacg aagaaaatgg ctatgtggtg actaagccca aactgtggac ttaacctaat
      721 ttctctatga aattgaagtc tgcttttggt cctgttacaa tgataatgtg caatgcatta
      781 aaaagcaaag acatgcgaat c
//
