LOCUS       NM_001107011            1277 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus mannose-P-dolichol utilization defect 1 (Mpdu1),
            mRNA.
ACCESSION   NM_001107011 XM_001078776 XM_220606
VERSION     NM_001107011.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1277)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   2  (bases 1 to 1277)
  AUTHORS   Schenk B, Imbach T, Frank CG, Grubenmann CE, Raymond GV, Hurvitz H,
            Korn-Lubetzki I, Revel-Vik S, Raas-Rotschild A, Luder AS, Jaeken J,
            Berger EG, Matthijs G, Hennet T and Aebi M.
  TITLE     MPDU1 mutations underlie a novel human congenital disorder of
            glycosylation, designated type If
  JOURNAL   J Clin Invest 108 (11), 1687-1695 (2001)
   PUBMED   11733564
  REMARK    Erratum:[J Clin Invest. 2003 Mar;111(6):925]
REFERENCE   3  (bases 1 to 1277)
  AUTHORS   Anand M, Rush JS, Ray S, Doucey MA, Weik J, Ware FE, Hofsteenge J,
            Waechter CJ and Lehrman MA.
  TITLE     Requirement of the Lec35 gene for all known classes of
            monosaccharide-P-dolichol-dependent glycosyltransferase reactions
            in mammals
  JOURNAL   Mol Biol Cell 12 (2), 487-501 (2001)
   PUBMED   11179430
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_220606.4, XM_001078776.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ213141.1, FQ220130.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1277
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..1277
                     /gene="Mpdu1"
                     /note="mannose-P-dolichol utilization defect 1"
                     /db_xref="GeneID:303244"
                     /db_xref="RGD:1307699"
     exon            1..142
                     /gene="Mpdu1"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..783
                     /gene="Mpdu1"
                     /codon_start=1
                     /product="mannose-P-dolichol utilization defect 1 protein"
                     /protein_id="NP_001100481.1"
                     /db_xref="GeneID:303244"
                     /db_xref="RGD:1307699"
                     /translation="MAGETDGPFKGVLVPILLPEKCYDQFFVHWDLLHVPCLKILLSK
                     GLGLGIVAGSLLVKLPQIFKLLGAKSAEGLSLQSVMLELVALTGTMVYSITNNFPFSS
                     WGEALFLTLQTVTICFLVMHYRGETVKGVAFLVCFAVVLLALLSPVMPLAVPTLLQAS
                     NVPAVVVGKLLQAATNYHNGHTGQLSAITVFMLFGGSLARIFTSVQETGDPLMAGVFV
                     VSSLCNGLIAAQVLFYWNAKAPHKQKKQQ"
     exon            143..208
                     /gene="Mpdu1"
                     /inference="alignment:Splign:2.1.0"
     exon            209..341
                     /gene="Mpdu1"
                     /inference="alignment:Splign:2.1.0"
     exon            342..427
                     /gene="Mpdu1"
                     /inference="alignment:Splign:2.1.0"
     exon            428..546
                     /gene="Mpdu1"
                     /inference="alignment:Splign:2.1.0"
     exon            547..657
                     /gene="Mpdu1"
                     /inference="alignment:Splign:2.1.0"
     exon            658..1277
                     /gene="Mpdu1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcggggtta tccggactgg cggaagctac ctttccaaca tggcgggcga gactgacgga
       61 ccgttcaaag gggtgctggt accaattctt ttacctgaga aatgctatga tcaattcttc
      121 gtccactggg acttgcttca tgttccctgc ctcaagattc tcctcagcaa aggccttggg
      181 ctgggcatcg tggctgggtc acttcttgta aagctccccc agatatttaa actcttggga
      241 gccaagagtg cagaaggact gagtctccag tcagtaatgc tggagctagt ggcactgact
      301 ggaactatgg tctacagcat caccaacaac ttccccttca gctcttgggg tgaagcactg
      361 ttcctgacac tacagacggt taccatctgc ttcctggtca tgcactacag aggagagacc
      421 gtgaaaggag ttgctttcct tgtctgcttt gccgtggtcc tgttggcgct gctttcccca
      481 gtcatgcctc tggctgtgcc caccctgctc caggcctcca atgtacctgc tgtggtggtg
      541 gggaagttgc tccaggcagc cactaactac cacaacggac acacaggcca gctttcagcc
      601 attacagtgt ttatgctgtt tgggggctcc ttggcccgga tcttcacttc tgttcaggaa
      661 actggagatc ccctcatggc tggagtcttt gtggtctctt ctctctgcaa tggccttatt
      721 gctgcccagg tcctcttcta ctggaatgcg aaggctcccc acaagcagaa aaagcagcag
      781 tagagctagc ttctagaata attccacctc catccatcta ctcaactccc acatgacccg
      841 atctgctggt gcaacttaat caccctccat cccgatgtat ttgccacctc ctgagcctgg
      901 gcggtaggaa tagtaaagcc ctgccctcac tcacttcacc agttgcctgg gatccctcct
      961 tttaagcagc tgttttctca cgggagcagg tgattttgcc ctgtccacct tccttttgga
     1021 ccaaggacag agttgggaaa tgtggttgga agctagtgac tgcttccctc tgctgcccga
     1081 gtgggacgat ctattggacc ccagttctgg aggtggggga gggggagaat gactcagata
     1141 aggcctcaag gctgggcgag gagggtcctg ctgtggcagg tcctggcgga agggtgtgtg
     1201 gagaaggcgg cactggttgc cactgtagga agagaataca gataggacaa taaaagactc
     1261 aaacatgctt taattat
//
