LOCUS       NM_031749               2695 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus mannosyl-oligosaccharide glucosidase (Mogs),
            mRNA.
ACCESSION   NM_031749 XM_346707
VERSION     NM_031749.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2695)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   2  (bases 1 to 2695)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   3  (bases 1 to 2695)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   4  (bases 1 to 2695)
  AUTHORS   Ushijima,T., Yamamoto,M., Suzui,M., Kuramoto,T., Yoshida,Y.,
            Nomoto,T., Tatematsu,M., Sugimura,T. and Nagao,M.
  TITLE     Chromosomal mapping of genes controlling development, histological
            grade, depth of invasion, and size of rat stomach carcinomas
  JOURNAL   Cancer Res 60 (4), 1092-1096 (2000)
   PUBMED   10706129
REFERENCE   5  (bases 1 to 2695)
  AUTHORS   Shailubhai,K., Pukazhenthi,B.S., Saxena,E.S., Varma,G.M. and
            Vijay,I.K.
  TITLE     Glucosidase I, a transmembrane endoplasmic reticular glycoprotein
            with a luminal catalytic domain
  JOURNAL   J Biol Chem 266 (25), 16587-16593 (1991)
   PUBMED   1885588
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Nov 27, 2020 this sequence version replaced NM_031749.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF087431.1, SRR26643292.18564.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-352               JAXUCZ010000004.1  117179335-117179686
            353-582             JAXUCZ010000004.1  117179779-117180008
            583-779             JAXUCZ010000004.1  117180480-117180676
            780-2695            JAXUCZ010000004.1  117180823-117182738
FEATURES             Location/Qualifiers
     source          1..2695
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..2695
                     /gene="Mogs"
                     /gene_synonym="Gcs1"
                     /note="mannosyl-oligosaccharide glucosidase"
                     /db_xref="GeneID:78947"
                     /db_xref="RGD:69240"
     exon            1..352
                     /gene="Mogs"
                     /gene_synonym="Gcs1"
                     /inference="alignment:Splign:2.1.0"
     CDS             7..2511
                     /gene="Mogs"
                     /gene_synonym="Gcs1"
                     /EC_number="3.2.1.106"
                     /note="glycoprotein-processing glucosidase I; glucosidase
                     1"
                     /codon_start=1
                     /product="mannosyl-oligosaccharide glucosidase"
                     /protein_id="NP_113937.2"
                     /db_xref="GeneID:78947"
                     /db_xref="RGD:69240"
                     /translation="MARGERRRRAAAAEGARPLERARGAGRRDGRAGGARGSAGGAAL
                     AVVVLALAFGLSGRWVLAWLRVRRALTLHPAPSALPPDSSSPAVAPELFWGTYRPHVY
                     FGMKTRSPKPLLTGLMWAQQGATPGTPPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHI
                     YDGALRLTTEFVKRSGGHHGGDWSWRVTVEPQASGTPSFPLVSLFFYVVTDGQEVLLP
                     EVGAKGQLKFISGHTSELGDFRLTLLPPTTPGDTVPKHGSYNVFWSSNPGLPLLTDMV
                     KSHLNSWFHHRPPGASPERYLGLPGSLKWEERGPSGQGQFLVQQVTLKAPFSVEFVFE
                     SGSARTGRDQASEQLVGGQLTRALESHAAAFKERFERTFQLKEKGLSPEEQALGQVAL
                     SGLLGGIGYFYGQGLVLPDTGMEGSEQKMDPSLFPPVPLFSGVPSRSFFPRGFLWDEG
                     FHQLVVQRWDPHLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAAHAN
                     PPTLLLPVIHMLEGRAPEDLAFLRRAFPRLHAWFSWLHQSQAGPVPLSYRWRGRDLAL
                     PTLLNPKTLPSGLDDYPRASHPSAAERHLDLRCWVTLGARVLSQLAEELGETEAAAEL
                     GPLAASLEAAGSLDELHWAPELGVFADFGNHTKAVQLKSRPPQGLVRVVGRPPPRLQY
                     VDALGYVSLFPLLLQLLEPSSPRLGPLLDVLADSRHLWSPFGLRSLSASSLFYKQRNT
                     EHDPPYWRGAVWLNINYLALGALHHYGRVEGPHKVQAAKLYRELRANVVSNVRQQYQA
                     TGFLWEQYSDQDGRGMGCRPFQGWTSLVLLIMAEEY"
     exon            353..582
                     /gene="Mogs"
                     /gene_synonym="Gcs1"
                     /inference="alignment:Splign:2.1.0"
     exon            583..779
                     /gene="Mogs"
                     /gene_synonym="Gcs1"
                     /inference="alignment:Splign:2.1.0"
     exon            780..2695
                     /gene="Mogs"
                     /gene_synonym="Gcs1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcccgcatgg cccggggcga gaggcgacgg cgcgctgcgg ccgcagaggg ggcgcggccg
       61 ctggagaggg cgcggggtgc gggccggcgg gatggcagag ccggcggggc gcgcggctcg
      121 gcgggcggcg cggccctggc cgtggtggtt ttggcgctgg ccttcggcct gtcggggcgc
      181 tgggtgctgg cgtggctccg tgtgcgccgc gcgctcacac tgcaccccgc tccgtcagcg
      241 ctaccgccgg actcctccag tcctgccgtg gccccggaac tcttctgggg tacctatcgc
      301 ccacacgtct atttcggcat gaagactcgc agccccaaac cactgctcac gggactgatg
      361 tgggcgcagc aaggcgccac cccggggacc cctcctaagc tcaggcacac atgcgaacaa
      421 ggagacggcg tgggtcccta tggctgggag ttccatgatg gactctcctt tggtcggcaa
      481 catatctatg atggggcctt aaggctcacc actgagttcg tcaagagatc tgggggtcat
      541 cacggagggg attggagctg gagagtgacc gtagagcctc aggcctcagg tacaccttcc
      601 ttccctttgg tgtccctgtt cttctacgtg gtaacagatg ggcaagaggt cctactacca
      661 gaggttggag ccaaaggaca gttgaagttc atcagtgggc acaccagtga acttggtgac
      721 ttccgcctca cacttctgcc accaaccact ccaggagaca ctgtccctaa gcatggcagc
      781 tacaatgtct tctggtcctc caacccaggg ctgcctctgc tcacagacat ggtaaagagc
      841 cacctaaaca gctggtttca tcaccggccc ccaggagcct ctccggaacg ataccttggc
      901 ttgcctggat ctcttaagtg ggaagagaga ggccctagtg ggcaagggca gttcttggtc
      961 cagcaggtga cactgaaagc ccctttctct gtggagtttg tgtttgaatc tggcagtgcc
     1021 aggacaggaa gagaccaagc ctctgagcag ctggtaggtg gccaactgac ccgggccctg
     1081 gagagccatg ctgcagcatt caaggagcgt tttgagagga ccttccagct aaaggagaag
     1141 ggcctgagcc ctgaggagca ggctctgggt caggttgccc tcagtggcct acttggtggg
     1201 attggttact tctatggaca gggtttggtg ttgccagaca ctggcatgga agggtctgaa
     1261 cagaaaatgg acccttccct atttccgcct gtcccccttt tctctggggt cccttcccgg
     1321 tcattcttcc cacgaggctt cctctgggat gaaggctttc accagctagt ggtccagcga
     1381 tgggatcccc acctcacccg ggaggcccta ggacactggc tggggctgct caatgctgac
     1441 ggttggattg ggcgagagca gattctgggg gatgaggcca gagcccgagt gcccccggaa
     1501 ttcctagtgc aacgtgcagc ccatgccaac cctccaaccc tgctcctgcc agtcatacac
     1561 atgctagaag gccgggcccc tgaggacttg gccttcctgc gcagggcttt cccccgcttg
     1621 catgcctggt tctcttggct ccatcaaagt caggcagggc cagtgccact ttcctaccgc
     1681 tggcggggca gggatctagc tttgcctacc ctacttaacc ccaagacact gccctcgggc
     1741 ctggatgact accccagggc ctcacatcct tctgcagcag agcggcacct ggacctgcgg
     1801 tgctgggtga cattgggtgc ccgggtgctg tcacagcttg cagaagagct tggggagact
     1861 gaagctgctg cagagttggg cccattggct gcctctctag aagcagctgg aagtctcgat
     1921 gagctgcact gggctcctga gctgggtgtc tttgccgact ttgggaacca cacaaaagca
     1981 gtacagctca agtctaggcc cccacagggg ctggttaggg tggtaggcag gcctccacct
     2041 cgactgcagt atgtggatgc cctgggctat gtctctcttt ttcctttgct gctacaactg
     2101 ctggagccca gctcaccccg cttgggaccc ctgctggacg ttctagctga tagccgccat
     2161 ctctggagcc cctttgggtt gcgctccctt tcagcctcca gtctctttta taaacagcga
     2221 aatacggaac acgatccacc ttactggcga ggtgcggtgt ggctgaatat caactacctg
     2281 gctttggggg cactacacca ctatgggcgt gtggagggtc ctcacaaggt tcaggctgcc
     2341 aaactctacc gtgaacttcg ggccaatgta gtaagcaacg tacggcagca ataccaggct
     2401 acagggtttc tgtgggaaca gtacagtgac caggatgggc ggggcatggg ctgccgcccc
     2461 ttccaaggat ggaccagtct tgttttactg atcatggctg aagagtacta gtgggacaga
     2521 aggaaagcta ggcctttgtg tcacttggaa tatgcagaca agggcttggg tttctggtct
     2581 cagtgtttca gatcctgtaa gctcatctca ggtgtctcct tattgtcatc ccatacagct
     2641 ctggggtgaa cgtgaactca aagagtctat ttttctaaat aaactggaaa acaac
//
