LOCUS       NM_001395671            3100 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus molybdenum cofactor sulfurase (Mocos), mRNA.
ACCESSION   NM_001395671 XM_006254466
VERSION     NM_001395671.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3100)
  AUTHORS   Ichida,K., Matsumura,T., Sakuma,R., Hosoya,T. and Nishino,T.
  TITLE     Mutation of human molybdenum cofactor sulfurase gene is responsible
            for classical xanthinuria type II
  JOURNAL   Biochem Biophys Res Commun 282 (5), 1194-1200 (2001)
   PUBMED   11302742
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000018.1.
            
            On Jul 30, 2021 this sequence version replaced XM_006254466.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360172.1380013.1,
                                           SRR26360186.462870.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-578               JAXUCZ010000018.1  16206402-16206979
            579-668             JAXUCZ010000018.1  16213015-16213104
            669-735             JAXUCZ010000018.1  16217597-16217663
            736-1377            JAXUCZ010000018.1  16219376-16220017
            1378-1454           JAXUCZ010000018.1  16223636-16223712
            1455-1654           JAXUCZ010000018.1  16225620-16225819
            1655-1771           JAXUCZ010000018.1  16227247-16227363
            1772-2197           JAXUCZ010000018.1  16230019-16230444
            2198-2360           JAXUCZ010000018.1  16233042-16233204
            2361-2439           JAXUCZ010000018.1  16235748-16235826
            2440-2564           JAXUCZ010000018.1  16239417-16239541
            2565-2670           JAXUCZ010000018.1  16242959-16243064
            2671-2809           JAXUCZ010000018.1  16246116-16246254
            2810-2914           JAXUCZ010000018.1  16250334-16250438
            2915-3100           JAXUCZ010000018.1  16251743-16251928
FEATURES             Location/Qualifiers
     source          1..3100
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p12"
     gene            1..3100
                     /gene="Mocos"
                     /note="molybdenum cofactor sulfurase"
                     /db_xref="GeneID:361300"
                     /db_xref="RGD:1308496"
     exon            1..578
                     /gene="Mocos"
                     /inference="alignment:Splign:2.1.0"
     CDS             437..3025
                     /gene="Mocos"
                     /EC_number="2.8.1.9"
                     /codon_start=1
                     /product="molybdenum cofactor sulfurase"
                     /protein_id="NP_001382600.1"
                     /db_xref="GeneID:361300"
                     /db_xref="RGD:1308496"
                     /translation="MACGATERGPEPPAFQRHPEASAPRLAHGYGLRSMSELRDQEFG
                     RLAGTVYLDHAGATLFPQSQLTNFTKDLMENVYGNPHSQNITSKLTHDTVEQVRYRVL
                     THFHTTPEDYSVIFTAGSTAALRLVAETFPWVSRSPENSGSHFCYLTDNHTSVVGMRT
                     VAATMNVTSTPVKPEDMWSAEGKGAGACDPDCQLPHLFCYPAQSNFSGTRYPLSWIDE
                     VKSGQRSPVRAPGKWFVLLDAASYVSTSPLDLSAHQADFIPISFYKIFGLPTGLGALL
                     VNKRVAPLLRKGYFGGGTAAVYLAGEDFYIPRSSVAERFEDGTISFLDVIALKHGFDV
                     LERLTGGMVNIQQHTFALLHFTHSALSSLRYPNGAPVVRIYGDSGFSSPDVQGPIINF
                     NVLDDAGKIIGYSQVDKMASLYNIHLRTGCFCNLGACQRHLGLSEEMVKKHFQAGHVC
                     GDDVDIIDGRPTGSVRISFGYMSTLEDAQAFLRFISTIYLRSPGGQPVPQASTSDTGV
                     LSSKSDCQSPQEGPCADPAVSSGSYPDINTVDLDLSQSKASSIQPIPQEKVAGILNGD
                     LGSHIVTNIYLYPIKSCAAFEVTKWPVGSQGLLYDRSWMVVNHNGVCLSQKQEPRLCL
                     IQPCIDLQQKVMVIKAEGMEPIQVPLEEDGERTQICQSRVCADRVNTYDCGENVSRWL
                     SKFCGRPCHLIKQSPHFQRNAKKTPKQGHPPGTAVALSLVNEAQYLLVNTSSVLELQQ
                     QLNASDERGKEESFSVKDLISRFRANIITKGARAFEEEQWDEISIGSLHFQVLGPCHR
                     CQMICIDQKTGQRNQDVFQKLSESRGRKVNFGVYLMHSSLDLSSPCFLSVGSEVLPVL
                     KDCGVS"
     exon            579..668
                     /gene="Mocos"
                     /inference="alignment:Splign:2.1.0"
     exon            669..735
                     /gene="Mocos"
                     /inference="alignment:Splign:2.1.0"
     exon            736..1377
                     /gene="Mocos"
                     /inference="alignment:Splign:2.1.0"
     exon            1378..1454
                     /gene="Mocos"
                     /inference="alignment:Splign:2.1.0"
     exon            1455..1654
                     /gene="Mocos"
                     /inference="alignment:Splign:2.1.0"
     exon            1655..1771
                     /gene="Mocos"
                     /inference="alignment:Splign:2.1.0"
     exon            1772..2197
                     /gene="Mocos"
                     /inference="alignment:Splign:2.1.0"
     exon            2198..2360
                     /gene="Mocos"
                     /inference="alignment:Splign:2.1.0"
     exon            2361..2439
                     /gene="Mocos"
                     /inference="alignment:Splign:2.1.0"
     exon            2440..2564
                     /gene="Mocos"
                     /inference="alignment:Splign:2.1.0"
     exon            2565..2670
                     /gene="Mocos"
                     /inference="alignment:Splign:2.1.0"
     exon            2671..2809
                     /gene="Mocos"
                     /inference="alignment:Splign:2.1.0"
     exon            2810..2914
                     /gene="Mocos"
                     /inference="alignment:Splign:2.1.0"
     exon            2915..3100
                     /gene="Mocos"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgcagtcga ccacagcagt ccaagtggac ttgctggtct ggagcgcagg gggcaaggat
       61 cccaggttct gggccagtag gactcggagt cacatatgcc caggggaaaa gacacgcact
      121 ccgttgttcc tgccacctgc cttactggca cctagacatc ccaggactcg cacccaggtg
      181 tctagagtgt ctcttggtca gcgttaggct gtggcggtca ccgcagagtg cgcgaccgag
      241 ttctgtccca ggtgggcaaa ggccgcaccg aagtgaaagc tttcagtgag tctgcgagct
      301 gcaaggaggc cggcccgcga ggcaccgccc atgggtgggg acccgagtca cccagggctc
      361 agcactggcg aaatcgcctc ccttgctcac ttcccgggct gggcggtcta gatcccgtag
      421 acttcagacg cgatccatgg cctgcggggc gacagagcgg ggccctgagc ccccggcctt
      481 ccagcgccat ccagaagcca gcgcaccgcg cctggcccac ggctacgggt tgcgcagcat
      541 gagcgagctg cgggaccagg agtttggccg cctagcagga actgtctatc ttgaccatgc
      601 aggagccacc ttgttccccc agagccagct cacaaacttc actaaggatc tcatggaaaa
      661 tgtctatggt aatcctcaca gccagaacat caccagcaaa ctcacccatg acacggtgga
      721 gcaggtccga tacagggtcc tgactcactt tcacaccacc ccagaggact acagcgtgat
      781 cttcacagcc gggagcacgg ctgctctcag gctggtggca gagacctttc cgtgggtgtc
      841 ccggtcccca gagaacagtg ggagtcactt ctgttacctc actgacaacc acacctctgt
      901 ggtgggaatg aggacggtgg ctgccaccat gaatgtcaca tctaccccag tcaagcccga
      961 ggacatgtgg tcggccgagg ggaagggtgc tggagcctgt gaccccgact gtcagcttcc
     1021 acacctcttc tgttacccag ctcagagtaa cttttcaggc accagatacc cactgtcatg
     1081 gatagatgag gtcaagtctg ggcagaggag tcctgtgaga gcgcctggga agtggtttgt
     1141 gctgcttgat gcggcctcct atgtcagcac ttcccccttg gatctgtcag ctcaccaggc
     1201 tgacttcatc cccatctcct tctataagat ctttgggctt cccacaggcc tgggtgctct
     1261 gctagtcaat aagcgcgtgg ctcctctgct gaggaaaggc tacttcggag gagggactgc
     1321 agccgtctac cttgccgggg aagactttta catcccaagg tcatcggtgg cagaaaggtt
     1381 cgaagacggc accatctcat tccttgatgt aatagcgttg aagcatggat ttgatgtgct
     1441 ggagcgcctc acaggtggca tggtgaacat acaacagcac acctttgctc tgctgcactt
     1501 tacccactct gccctgtcct ccctccgcta tcccaacggg gccccagtgg tgcgcattta
     1561 cggtgactct gggttcagca gccctgacgt ccagggtcca atcatcaatt ttaatgtact
     1621 ggatgatgct gggaagatca tcggctactc ccaggtggac aaaatggcaa gcctgtacaa
     1681 catccacctg aggactggct gcttctgtaa cttgggggcc tgccagaggc acctggggct
     1741 aagtgaagag atggttaaga aacattttca ggctggtcat gtctgtggag atgatgttga
     1801 cattatagac ggacgaccca ccggctctgt gaggatttcc tttggataca tgtccacact
     1861 agaagatgcc caggcctttc tcaggtttat cagcactatc taccttcgct cacccggtgg
     1921 ccagcctgtt cctcaagcca gcaccagtga cactggagtc ttatcctcaa agagtgactg
     1981 tcagtcacct caggaaggtc cctgcgcaga ccctgcagtt tccagtggct cctatcctga
     2041 catcaatacc gtggacttgg acctgtctca gagcaaagcc agtagcatcc agccgatccc
     2101 tcaagagaaa gttgcaggta tcctgaatgg ggaccttggg tcccacattg tcaccaacat
     2161 ttacctctac cccatcaaat cctgtgctgc gtttgaggtg actaagtggc ccgtggggag
     2221 ccaagggctg ctgtatgacc ggagctggat ggttgtgaat cacaacggcg tttgcctgag
     2281 tcagaagcag gagccacggc tctgcctgat ccagccctgc atcgacctgc agcagaaggt
     2341 catggtcatc aaagcagaag ggatggagcc gatacaggtg cctcttgagg aagacggtga
     2401 acggacccag atttgccaaa gcagagtgtg tgcagacagg gtaaatactt acgattgtgg
     2461 agaaaatgtt tcaagatggc tgtccaagtt ttgtggccgt ccatgccatt taatcaagca
     2521 aagtccacac ttccagcgaa atgcaaagaa gacgcctaaa caaggtcatc ctcccggcac
     2581 tgctgttgcc ctgtccctgg tgaatgaggc tcagtatctg ttggtgaaca catcaagtgt
     2641 tctggagctt cagcagcagc taaacgccag tgacgaacgt ggaaaggagg aatcattctc
     2701 tgtgaaagat ctcatctccc gcttccgtgc caatattatt accaagggag ccagggcttt
     2761 tgaagaagag cagtgggatg agatttcgat tggctccttg catttccagg ttctggggcc
     2821 ttgtcacagg tgccagatga tttgtatcga ccagaaaact ggccagcgga accaggatgt
     2881 cttccagaag ctttctgaga gccgggggag aaaggtgaac tttggcgtgt acctgatgca
     2941 ctcgtccttg gatttatcgt ctccgtgttt cctgtcagtg ggatctgagg tactccctgt
     3001 gttgaaagac tgtggagtgt cttgattcac cctcttccca gccataccca cgtgctatct
     3061 cctgacattt ctcccaagag cattaaagtt tttctttaaa
//
