LOCUS       NM_001135780            4379 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus MMS22-like, DNA repair protein (Mms22l), mRNA.
ACCESSION   NM_001135780 XM_232837
VERSION     NM_001135780.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4379)
  AUTHORS   O'Connell,B.C., Adamson,B., Lydeard,J.R., Sowa,M.E., Ciccia,A.,
            Bredemeyer,A.L., Schlabach,M., Gygi,S.P., Elledge,S.J. and
            Harper,J.W.
  TITLE     A genome-wide camptothecin sensitivity screen identifies a
            mammalian MMS22L-NFKBIL2 complex required for genomic stability
  JOURNAL   Mol Cell 40 (4), 645-657 (2010)
   PUBMED   21055985
REFERENCE   2  (bases 1 to 4379)
  AUTHORS   Duro,E., Lundin,C., Ask,K., Sanchez-Pulido,L., MacArtney,T.J.,
            Toth,R., Ponting,C.P., Groth,A., Helleday,T. and Rouse,J.
  TITLE     Identification of the MMS22L-TONSL complex that promotes homologous
            recombination
  JOURNAL   Mol Cell 40 (4), 632-644 (2010)
   PUBMED   21055984
REFERENCE   3  (bases 1 to 4379)
  AUTHORS   O'Donnell,L., Panier,S., Wildenhain,J., Tkach,J.M., Al-Hakim,A.,
            Landry,M.C., Escribano-Diaz,C., Szilard,R.K., Young,J.T., Munro,M.,
            Canny,M.D., Kolas,N.K., Zhang,W., Harding,S.M., Ylanko,J.,
            Mendez,M., Mullin,M., Sun,T., Habermann,B., Datti,A., Bristow,R.G.,
            Gingras,A.C., Tyers,M.D., Brown,G.W. and Durocher,D.
  TITLE     The MMS22L-TONSL complex mediates recovery from replication stress
            and homologous recombination
  JOURNAL   Mol Cell 40 (4), 619-631 (2010)
   PUBMED   21055983
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Oct 11, 2008 this sequence version replaced XM_232837.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.26835.1,
                                           SRR26643294.20626.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-559               JAXUCZ010000005.1  42994414-42994972
            560-685             JAXUCZ010000005.1  42995772-42995897
            686-735             JAXUCZ010000005.1  42997326-42997375
            736-823             JAXUCZ010000005.1  42999725-42999812
            824-1004            JAXUCZ010000005.1  42999904-43000084
            1005-1095           JAXUCZ010000005.1  43002921-43003011
            1096-1226           JAXUCZ010000005.1  43005047-43005177
            1227-1340           JAXUCZ010000005.1  43005985-43006098
            1341-1514           JAXUCZ010000005.1  43021287-43021460
            1515-1577           JAXUCZ010000005.1  43027202-43027264
            1578-1697           JAXUCZ010000005.1  43032275-43032394
            1698-1924           JAXUCZ010000005.1  43035842-43036068
            1925-2434           JAXUCZ010000005.1  43037920-43038429
            2435-2628           JAXUCZ010000005.1  43077874-43078067
            2629-2779           JAXUCZ010000005.1  43082700-43082850
            2780-2928           JAXUCZ010000005.1  43086376-43086524
            2929-3071           JAXUCZ010000005.1  43087261-43087403
            3072-3231           JAXUCZ010000005.1  43093069-43093228
            3232-3401           JAXUCZ010000005.1  43095125-43095294
            3402-3613           JAXUCZ010000005.1  43098317-43098528
            3614-3777           JAXUCZ010000005.1  43103555-43103718
            3778-3874           JAXUCZ010000005.1  43106165-43106261
            3875-4042           JAXUCZ010000005.1  43107536-43107703
            4043-4379           JAXUCZ010000005.1  43110035-43110371
FEATURES             Location/Qualifiers
     source          1..4379
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q21"
     gene            1..4379
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /note="MMS22-like, DNA repair protein"
                     /db_xref="GeneID:313108"
                     /db_xref="RGD:1304693"
     exon            1..559
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     CDS             402..4124
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /codon_start=1
                     /product="protein MMS22-like"
                     /protein_id="NP_001129252.1"
                     /db_xref="GeneID:313108"
                     /db_xref="RGD:1304693"
                     /translation="MDGGSAASTFLTDSLELELGTEWCKPPCFSCAFDSRDGKFSGES
                     YLASGALKRLILNLDPLPTNFEEDTVELFGIQWVTETALVHSCRELFHLFRQQIFNLE
                     SLLQVNCDFGKIAALHAKADSIRQQCVVFLHYLKVFIFRWLKVQEAESHSLLVHPYEV
                     LEAQLPSMLVDELHGLLLYIGHLAELPSVTLGAFVNQNQIKLFPPSWHLLHLFLDTHW
                     LVLEILHMLGEKLKQVVYGRQFISQAGDSLTNVSLFEEHCEHLFCDLICLSLNRYDKV
                     MPSEALMISHYPCSCVKELWVLLIHLLDHRSKWSAAESFWNWLNKLLRTLFEKSSEQR
                     RPVSITHAKDPLGFSWWISVHVASLFQIDRHGVLDEMRQMESNWSFVEELLKQSVTVQ
                     DGILEEQLRMHLHCCLTLCDFWEPNLSVVTILWEYYCKNLNSSFSISWLPLKGLTNII
                     KSPLSMLTLVKNCYCDKQDPDLYKSSSSYIIFLCILAKVVKKAMKNSGSHPWKQVKGR
                     IYSKFHQRRMEELTEVGLQNFFCLFLLLAAVAEIEDVASHVLDLLRFLRPASMSSHGT
                     LVWKGQMAFLLMYAQKNLDIGVWAEKLSCEFQEKAKEFLVSKHDEMVQRHDLWTQLSI
                     YIDGVQEVFETSSCLCPSHEHLLNDGFSMLLRACRESELRTVLSFLQAVLARIRSIRQ
                     QLCQELQRENVDRILQSSLSAKERPLAAVAGALWRHFFSFLKSQRMTQVVPLSQLADA
                     AADFTLLAVDMPNTAPPDLQPQPVISIMQLFGWDDIIWPQVVARYLSHLLQNSTVCEA
                     LSQSSCVSFQSLTIRSWVRCVLQMYVKHLSEPDLLIDMNPDQVMEKEYMEQLTEMTRL
                     LFTLSEVKNIFSKAQIEYLPNPEDPKQALIQFLEAVGVTYRTLQTFSDKSAMVTKSLE
                     YLGEILKYIKPYLGKKVSSAGLQLTYGIMGILVKSWAQIFATSKAQKLLFRIIDCLLL
                     PHTVLQQDKELPVPMLTAIQKTLPLYLQGICAVCCQSQNPNAYLNQLLRNVIEQYIGR
                     FLPASPSVSDLGQHPVLLALRSPASVPWMMPLRKHIVHAIRKSYLEFKGSSPPPRLAS
                     VLAFILQLFKDTTLGVCDLELLLPGVLKCLVLVNEPQVKRLATENLQCMVKTCQVGSE
                     GGPATQLTSLFRQFIQDYGMQYSYQVYSILETVAALSQHIGIQLIPTLTQSLKDSELK
                     WGLGKNIAQREAYSKLLSRLGQAGQDEKQRLESDKL"
     exon            560..685
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            686..735
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            736..823
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            824..1004
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            1005..1095
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            1096..1226
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1340
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            1341..1514
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            1515..1577
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            1578..1697
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            1698..1924
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            1925..2434
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            2435..2628
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            2629..2779
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            2780..2928
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            2929..3071
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            3072..3231
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            3232..3401
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            3402..3613
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            3614..3777
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            3778..3874
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            3875..4042
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
     exon            4043..4379
                     /gene="Mms22l"
                     /gene_synonym="RGD1304693"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtatcggatc ccgcgatttt cctgagcgct ctcccgcccc gaacgccgcg ctgcggcgga
       61 gggaggcggc ggggctccgt gcaccatccc gacccgctcc aggaaaccag cttgaggtgc
      121 gtgagggcct ccaaacccac tgcagcccgg agggagcgag ggcggcgttg gaagtcctgg
      181 cggctccggt gtctggggcc ggcgccctag aggacgcccg gaggtttctg aacctgttgc
      241 cttctcagct tctctgtttt aactttgttt tccccatgtg ctgagggcac attttgggtc
      301 tccgaggtgg tcccttaacc tttcaacttc ttgcaacttg tctttggagc tttaccgata
      361 actacggagc cgcggtgtca tttccgagca tgatgtaaat aatggatggc ggttcagcag
      421 cgtccacctt cttgactgac agcttagagc tggagctggg gacagagtgg tgcaaacccc
      481 cctgcttttc ttgcgctttt gacagcagag acggaaaatt ttctggagag tcctaccttg
      541 ccagtggcgc ccttaagcgg ttaattttaa atcttgatcc attaccaact aactttgaag
      601 aggatacagt agaactattt ggcatccaat gggttactga aacagcacta gtacattcat
      661 gtcgagaact ctttcattta ttcaggcaac agatatttaa cttggagtct ttgttacaag
      721 tcaactgcga ttttgggaag atagccgcct tgcacgccaa agcagacagc attaggcagc
      781 aatgtgtagt atttcttcac taccttaaag tcttcatctt caggtggctg aaagtacaag
      841 aagcagagag ccacagtctc cttgtccatc cctatgaggt tttggaagct cagcttccct
      901 cgatgttggt tgatgagctt catggattac ttctatatat tggacatcta gctgaacttc
      961 ccagtgttac tctaggagca tttgtaaatc aaaaccagat taagctcttc cctccatcat
     1021 ggcatttatt acatctcttc ttagacaccc attggctggt gttggaaata ctgcacatgc
     1081 tgggagaaaa attaaaacaa gttgtttatg gtcgtcagtt cattagtcag gcgggcgaca
     1141 gtttaaccaa tgtcagcctc tttgaagaac attgtgaaca tcttttctgt gacttaatat
     1201 gcctgtcact caacagatat gacaaggtta tgccttcaga agcattaatg attagtcact
     1261 acccatgctc ctgtgttaaa gaattatggg ttctacttat tcatcttcta gaccacagaa
     1321 gtaaatggtc tgctgcagaa tcattttgga attggttgaa taaactactt agaacacttt
     1381 ttgaaaaatc aagtgagcaa agaagacctg tttctataac ccatgccaag gatccattag
     1441 gctttagttg gtggattagt gttcatgtag catcattgtt ccagattgat cgccatggtg
     1501 tattggatga aatgagacag atggaatcaa attggagctt tgtagaagaa cttttgaaac
     1561 agtctgtcac tgttcaggat ggtatattag aagagcagtt acgaatgcat cttcattgtt
     1621 gtttgacact ttgtgatttt tgggagccaa acctttcagt tgtcaccatt ttatgggagt
     1681 attattgtaa gaacctgaat agctccttca gtatttcttg gcttcctttg aaaggcctta
     1741 ctaatattat caagtcacca ctgtcgatgc ttacactggt gaagaactgc tattgtgata
     1801 aacaagaccc tgacctgtat aagtccagca gcagttacat catttttctt tgcattttgg
     1861 caaaagttgt taagaaagca atgaaaaaca gtggctctca tccttggaaa caagttaaag
     1921 gaagaatata ttctaaattt catcaaagaa ggatggaaga actaactgaa gttggcctac
     1981 agaacttttt ctgccttttt ctactgttag cagctgttgc agagatagaa gatgtagcaa
     2041 gccatgtctt agacctcctt cgtttcctca ggcccgcctc catgtcctct catggcaccc
     2101 ttgtttggaa gggtcagatg gcatttctcc tgatgtacgc ccagaaaaac ctggacattg
     2161 gtgtttgggc cgagaagctg tcctgtgagt tccaagagaa agcaaaggag ttcttggtgt
     2221 ctaagcatga tgaaatggta cagagacatg atctgtggac acagctttcc atctacattg
     2281 atggtgttca agaagtgttt gagaccagct cctgcttgtg tccttctcac gagcaccttc
     2341 tcaatgatgg attcagcatg ttactgcgag cctgtcggga gtctgaactt aggaccgtgc
     2401 tgagctttct gcaagctgtc ctggccagaa tcaggagtat ccgtcagcaa ttgtgtcagg
     2461 aacttcagag agagaatgtg gaccggatcc tgcagtcttc attatcggct aaagagcgcc
     2521 ccctggctgc cgtcgccggt gcactgtgga ggcatttctt ttcctttctc aagagtcaga
     2581 gaatgacaca agtggtgcct ctctcccagc ttgcagatgc tgctgcagat tttactctgc
     2641 tagcagtgga catgccaaac acagcaccac cagatcttca gcctcagcca gttatatcaa
     2701 taatgcagct ttttggttgg gatgatatca tctggcccca agttgtagca agatatttaa
     2761 gtcatttgtt acaaaatagc acagtatgtg aagcactttc tcagtcaagt tgtgtatctt
     2821 ttcaatcctt aactataaga tcgtgggtcc gttgtgtttt gcaaatgtac gtaaaacacc
     2881 tctctgaacc tgatttgctg attgatatga atcctgacca ggtcatggaa aaagagtaca
     2941 tggaacagct gactgaaatg acaagattac tatttactct ctctgaagta aagaatatct
     3001 tctcaaaggc tcaaattgaa tatttgccca acccagaaga ccccaaacaa gcacttatac
     3061 agttccttga ggctgttggt gtgacttaca gaactctcca gacattttct gataaatctg
     3121 ccatggtcac taagtcctta gaataccttg gtgaaatatt aaaatacata aaaccctatt
     3181 tggggaaaaa agtttccagt gcagggttgc agctgactta tgggataatg ggaattcttg
     3241 ttaaatcatg ggcacaaatc ttcgccacct ctaaagcaca gaaattactg tttcggataa
     3301 tagactgttt attgctgcca catacagtgt tacagcaaga caaggagttg cctgtaccca
     3361 tgttgactgc aattcagaag actcttcctc tgtatctaca gggcatatgt gctgtgtgct
     3421 gccagtctca aaatccaaac gcctacttga atcagttgct aaggaatgtc attgagcagt
     3481 atatagggcg gtttctccca gcctcaccca gtgtttcgga tcttggacag catcctgttc
     3541 tgttggcact gagaagccct gcctctgttc cgtggatgat gcctttaaga aagcacattg
     3601 tccatgccat caggaaatcc tatcttgagt ttaaagggtc ctcaccccct cctcgattag
     3661 catccgtatt ggccttcatc ctccagctct tcaaggatac cacattgggt gtttgtgacc
     3721 ttgaactgct ccttcctgga gtcttaaagt gtttggtgtt ggtaaatgaa ccccaagtta
     3781 aaaggctggc cacagagaac ctgcagtgca tggtaaaaac ctgccaagtg gggtcagaag
     3841 gaggacctgc cacccagctg acttctctgt ttaggcagtt catccaggac tacggtatgc
     3901 aatacagtta tcaagtatac agcatcctgg agacagtagc agcactgagt cagcacattg
     3961 gcatccagtt gattcctacc ctcactcagt ctctgaagga ttccgagctg aaatggggcc
     4021 tcggcaaaaa tattgcacag agggaagcat atagcaaact tttatctcgc ctaggacagg
     4081 cggggcagga tgagaagcag agactggaaa gtgataagct gtgatgctgc cgcgtggttc
     4141 ttcctgtctg cgatgtctct gtctaaagct gctctgtgcc actcgagctg gtactgtaat
     4201 taattgtgtg acgttgtatc acaaataacc tccttctttg cctgcatata tgaagtatat
     4261 ataaatatat aaggaggaag gctaattagt aactgtataa taggatacta ggaactctgt
     4321 aaaactgtgc tctattttga agagattttt aactaaatta aagacctttt gaaccagaa
//
