LOCUS       NM_001106876            3721 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus MLLT1, super elongation complex subunit (Mllt1),
            mRNA.
ACCESSION   NM_001106876 XM_001056032 XM_001056088 XM_001056158 XM_001056216
            XM_238569
VERSION     NM_001106876.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3721)
  AUTHORS   Luo,Z., Lin,C. and Shilatifard,A.
  TITLE     The super elongation complex (SEC) family in transcriptional
            control
  JOURNAL   Nat Rev Mol Cell Biol 13 (9), 543-547 (2012)
   PUBMED   22895430
  REMARK    Review article
REFERENCE   2  (bases 1 to 3721)
  AUTHORS   Smith,E.R., Lin,C., Garrett,A.S., Thornton,J., Mohaghegh,N., Hu,D.,
            Jackson,J., Saraf,A., Swanson,S.K., Seidel,C., Florens,L.,
            Washburn,M.P., Eissenberg,J.C. and Shilatifard,A.
  TITLE     The little elongation complex regulates small nuclear RNA
            transcription
  JOURNAL   Mol Cell 44 (6), 954-965 (2011)
   PUBMED   22195968
REFERENCE   3  (bases 1 to 3721)
  AUTHORS   Kikuchi,Y., Hirano,M., Seto,M. and Takatsu,K.
  TITLE     Identification and characterization of a molecule, BAM11, that
            associates with the pleckstrin homology domain of mouse Btk
  JOURNAL   Int Immunol 12 (10), 1397-1408 (2000)
   PUBMED   11007757
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001106876.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643290.31646.1,
                                           SRR26643288.36485.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-214               JAXUCZ010000009.1  1862876-1863089     c
            215-395             JAXUCZ010000009.1  1854236-1854416     c
            396-478             JAXUCZ010000009.1  1847324-1847406     c
            479-622             JAXUCZ010000009.1  1831584-1831727     c
            623-748             JAXUCZ010000009.1  1828506-1828631     c
            749-1276            JAXUCZ010000009.1  1825676-1826203     c
            1277-1364           JAXUCZ010000009.1  1823338-1823425     c
            1365-1473           JAXUCZ010000009.1  1822185-1822293     c
            1474-1573           JAXUCZ010000009.1  1820613-1820712     c
            1574-1645           JAXUCZ010000009.1  1820449-1820520     c
            1646-1717           JAXUCZ010000009.1  1820285-1820356     c
            1718-3721           JAXUCZ010000009.1  1818204-1820207     c
FEATURES             Location/Qualifiers
     source          1..3721
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q11"
     gene            1..3721
                     /gene="Mllt1"
                     /note="MLLT1, super elongation complex subunit"
                     /db_xref="GeneID:301119"
                     /db_xref="RGD:1588581"
     exon            1..214
                     /gene="Mllt1"
                     /inference="alignment:Splign:2.1.0"
     CDS             203..1846
                     /gene="Mllt1"
                     /note="myeloid/lymphoid or mixed lineage-leukemia
                     translocation to 1 homolog; myeloid/lymphoid or
                     mixed-lineage leukemia (trithorax homolog, Drosophila);
                     translocated to, 1; myeloid/lymphoid or mixed-lineage
                     leukemia; translocated to, 1"
                     /codon_start=1
                     /product="protein ENL"
                     /protein_id="NP_001100346.1"
                     /db_xref="GeneID:301119"
                     /db_xref="RGD:1588581"
                     /translation="MDNQCTVQVKLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDI
                     QHFVEKVIFRLHDSFPKPKRVCKEPPYKVEESGYAGFIMLIEVYFKNKEEPRKVCFTY
                     DLFLNLEGNPPVNHLRCEKLTFNNPTTEFRCKLLMAGGVMVMPEGADTVSRPSPDYPM
                     LPTIPLSAFSDPKKNKPSHGSKDANKESGKASKPHKVAREHRERPRKDSESRSCSKEP
                     EREPKSAKDAARKLPKEEKAPVPKAAFKEPKMALKETKLESLSPKGVSQPPTLPKASS
                     KRPAATDSPKPSAKKPKKSGSKGARRAPGTSPRASSFPDKKVARDKSSKGDKGKMESE
                     PREAKRTLQAEDSNSEDEASFRSESAQSSPAHASSSSDSSSDSDFEPSQNHSQGPLRS
                     MVEDLQSEGSDEDDSSSGEESTVKTNPGRESRLSFSDSESDNSADSCLPGREPLPPQK
                     PPPPSSKVTGRRSPEPCSKPEKILKKATYDKAYTDELVELHRRLMALRERNVLQQIVN
                     LIEETGHFNVTNTTFDFDLFSLDESTVRKLQSCLEAVAT"
     exon            215..395
                     /gene="Mllt1"
                     /inference="alignment:Splign:2.1.0"
     exon            396..478
                     /gene="Mllt1"
                     /inference="alignment:Splign:2.1.0"
     exon            479..622
                     /gene="Mllt1"
                     /inference="alignment:Splign:2.1.0"
     exon            623..748
                     /gene="Mllt1"
                     /inference="alignment:Splign:2.1.0"
     exon            749..1276
                     /gene="Mllt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1277..1364
                     /gene="Mllt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1365..1473
                     /gene="Mllt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1474..1573
                     /gene="Mllt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1574..1645
                     /gene="Mllt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1646..1717
                     /gene="Mllt1"
                     /inference="alignment:Splign:2.1.0"
     exon            1718..3721
                     /gene="Mllt1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgaggccgg gcccgagtcg gtggctgggg gcccgcggtc gctgagcggt ccgggctggc
       61 ggcggtttcc ggttcagcgc ggctggcggg cgggaggccc ggagcggcgg cggcggcccc
      121 tgacagacaa tgagagcggc ggggcgttgc tgagcggcgg gggcaagagc gacgcggccc
      181 gggggcgggg cgggcgccag tcatggacaa tcagtgcacc gtccaggtga agttagagct
      241 ggggcatcgt gcccagctgc ggaagaaacc caccactgag ggcttcaccc atgactggat
      301 ggtttttgtg cgtggccctg aacagtgtga catccagcac tttgtggaga aggtcatctt
      361 ccgactgcat gacagcttcc ccaagcccaa gcgtgtgtgc aaggagcctc cctacaaagt
      421 ggaggagtca ggctacgcag gcttcatcat gctcatcgaa gtgtacttca aaaacaagga
      481 ggagccgagg aaggtctgct tcacctacga cctgttcctc aacctggagg gcaaccctcc
      541 tgtcaaccac ctgcgctgtg agaagctcac cttcaacaac cccaccactg agtttcgctg
      601 caagctactc atggccggcg gggtgatggt aatgcccgaa ggagcggaca cggtgtccag
      661 gcccagccct gactacccca tgttacccac aattccactc tctgccttct ctgaccccaa
      721 gaagaacaaa ccatcccacg gttccaagga cgccaacaag gagagtggca aggcttccaa
      781 accacacaag gtggccaggg agcaccgtga gcggccgcgt aaggactcag agagcaggag
      841 ttgctccaag gagccagagc gcgagcccaa gagtgccaag gatgctgcac gcaagctgcc
      901 caaggaggag aaggccccag tgcccaaggc tgccttcaag gagcccaaga tggccctaaa
      961 ggaaaccaag ctggagagcc tgtcccctaa gggtgtgtcc cagcctccta ccctgcccaa
     1021 ggcctccagc aagaggccag ctgccacaga ctcaccgaag cccagcgcca aaaagcctaa
     1081 gaagagtggg tcaaaggggg cacggcgtgc gccaggcacc tcaccccgtg cctcctcctt
     1141 ccctgacaag aaggtggcca gggacaagag cagcaaaggt gacaagggga agatggagag
     1201 tgagccaagg gaggccaagc ggactctgca ggctgaggac tcaaactctg aggatgaggc
     1261 ctccttccgg tcagagtcgg cccagtcaag cccagctcac gccagctcca gctctgactc
     1321 cagctctgac tccgactttg agccgtctca gaaccacagc caaggacccc tgcgctccat
     1381 ggtggaggac ctacagtctg aggggtcaga tgaggatgac tcatcatcag gagaggagag
     1441 caccgtcaag accaacccag gccgggagtc caggctaagc ttcagtgaca gcgagagtga
     1501 caacagtgct gactcctgcc tgcctggccg tgagcccctg cctccccaga agccaccccc
     1561 tccgagcagc aaggtgactg gtcggaggag ccccgagccc tgcagcaagc ctgaaaagat
     1621 tctgaagaag gctacctacg acaaggctta cacggacgag ctggtggagc tacaccggag
     1681 gctgatggct ctgcgtgagc gcaatgtgct gcagcagatc gtcaacctga tcgaggagac
     1741 tggtcacttc aatgtcacca acaccacctt cgactttgac cttttttcct tggatgaaag
     1801 cactgttcgc aagctgcaga gctgcctgga ggccgtggcc acatgaccct ggctgccact
     1861 gtggagccac ggtgggcatg gtgggcatgg tgggcatggg aggggctagg catgagggct
     1921 ggcccaccat ggcttccact cccctggtac cacccccaga taaccatggt gccccagtgc
     1981 ccctcagtgg ttggtgttga aggggtgctg caggccacac ttccacaggg tggggtgaca
     2041 taggacacat gtggcctgca gcccctcact tagtctctgc cagttgtcca ctgtaggtgg
     2101 aactgaatgg caggtcactg cctgggcctc tcttgagtgg ccaggatgac catagtcttc
     2161 cacacagttc acaggcctcc ttcagctggc ctgcctccta gacttgaggg tctgttagca
     2221 tggccaggac caactggaca cacctgcctc tgccatgcag ccttgtgtat tgtgtgtgct
     2281 ccaggtgagt ccagcactgg ggaggctcct gctacccctc tgctggaggc acagaggagc
     2341 tcccctctag atcccaggat gccactgcct cttgaggccc caggccagtg aacactacga
     2401 taggcaccaa tcttgggacc ccaagggcca ccactgcagc catgtgccag ccaagcaccc
     2461 acagttccaa ggctagctgg actggtactc ctgggccagc attccccatg ggccacctcc
     2521 tctgctctct cactgatcaa gtctttgaac tttgaaaaca cgagcttttg ccaaatatga
     2581 taggatggtg tgtgtgaggc gggcccagcc ccagactgct tctgttcctg gccacatggc
     2641 tctgcctcta cagtgcacct ggagaggctt tggacctgtg ccctgcaaac tgccaagggt
     2701 caagccagcc cccttcccat gtctgagcct ggagtaccac cccttcccca actccagttg
     2761 ttgtcagtgt ttgtgcccca accaagttgt ttgaaagcgg cctgagccga aactagctcg
     2821 cagttgcctc gttggtgttg cttcctcccc agtgtgggtt catccctgga ggcctggcct
     2881 cccagctccc tctccttgtc tctgtcccac tcccagaata tctgtcagga agatcctgaa
     2941 cactcccggg gaaccccagc ctctaaggct tcctttaccc ccagggaagg agaaggcctc
     3001 tgcctgcagc ccctgttccc actccctcca actgggggag acagggctca ggccccacac
     3061 ctcttcccac acaggccgac aatactctcc atcaggtgtt ctgcagcctc taagcctttg
     3121 cattgtggca gctgttggcc tccacatgga gtgcgccagg gtcccaaaca gcctcagccc
     3181 agggcactat tcttcctttc acggttgcca gcggcccagc tcttctgctg ccctgggcct
     3241 tggtgtctag tccttccaga tgcttccagg accctcctga gagcaccacc cgtctcttca
     3301 gttacctcct ctggccggaa ggtcatacca ctgtccccca gagccactct ggggcccata
     3361 ctgactgtct ggaagcctaa agaagcagcc tgcagccaga gccccgaggg ctttagggac
     3421 ttgtccatag gaaggggtgg caccatgtct gcccacggtc agtccctgtg ctgcagcctc
     3481 ctgaaccagt tcatgacact gagtgcaaaa ggtattggat acctatccct ccccagggct
     3541 tcacaagaca tgtcttcatg aatagacatg tcactggccc agatgagccc tggccagagg
     3601 gaccaggaga gctgtgtttg taatgagctg cagggccatt tgtcccgcat tttaaacttt
     3661 ttttttgtta aattgtgaaa tgatggagga attttataga aaataaagtg agatgggagc
     3721 a
//
