LOCUS       NM_001008314            2234 bp    mRNA    linear   ROD 12-JUN-2023
DEFINITION  Rattus norvegicus makorin, ring finger protein, 2 (Mkrn2), mRNA.
ACCESSION   NM_001008314 XM_238369
VERSION     NM_001008314.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2234)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 2234)
  AUTHORS   Gray TA, Azama K, Whitmore K, Min A, Abe S and Nicholls RD.
  TITLE     Phylogenetic conservation of the makorin-2 gene, encoding a
            multiple zinc-finger protein, antisense to the RAF1 proto-oncogene
  JOURNAL   Genomics 77 (3), 119-126 (2001)
   PUBMED   11597136
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083870.1.
            
            On Dec 16, 2004 this sequence version replaced XM_238369.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083870.1, SRR8487227.106077.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132273
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2234
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..2234
                     /gene="Mkrn2"
                     /note="makorin, ring finger protein, 2"
                     /db_xref="GeneID:297525"
                     /db_xref="RGD:1310618"
     exon            1..31
                     /gene="Mkrn2"
                     /inference="alignment:Splign:2.1.0"
     CDS             6..1259
                     /gene="Mkrn2"
                     /EC_number="2.3.2.27"
                     /note="probable E3 ubiquitin-protein ligase makorin-2"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase makorin-2"
                     /protein_id="NP_001008315.1"
                     /db_xref="GeneID:297525"
                     /db_xref="RGD:1310618"
                     /translation="MSTKQVTCRYFMHGVCREGSQCLFSHDLANSKPSTICKYYQKGY
                     CAYGARCRYDHTKPPAAAGGAVGPAPHPSPSSGLHSPHPSSDIATSVMRTHSNEPRKR
                     EKKTLVLRDRNLTGLAEDKTPPPSTVNNPGGCNDPQTSPEMKPHSYLDAIRTGLDDLE
                     ASSSYSNEQQLCPYAAAGECRFGDACVYLHGDMCEICRLQVLHPFDPEQRKAHEKMCM
                     STFEHEMEKAFAFQASQDKVCSICMEVILEKASASERRFGILSNCSHTYCLSCIRQWR
                     CAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGMGKKACKYFEQG
                     KGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSEGTVRFFNSVRLWDFIENRETRQVP
                     STDDVDVTELGDLFMHLSGVESSEP"
     exon            32..160
                     /gene="Mkrn2"
                     /inference="alignment:Splign:2.1.0"
     exon            161..342
                     /gene="Mkrn2"
                     /inference="alignment:Splign:2.1.0"
     exon            343..650
                     /gene="Mkrn2"
                     /inference="alignment:Splign:2.1.0"
     exon            651..865
                     /gene="Mkrn2"
                     /inference="alignment:Splign:2.1.0"
     exon            866..976
                     /gene="Mkrn2"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1121
                     /gene="Mkrn2"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..2211
                     /gene="Mkrn2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgccatgag caccaagcag gtcacctgca ggtattttat gcatggtgta tgtcgagaag
       61 gcagccagtg cctgttttca catgacttgg caaacagcaa gccgtccacc atctgcaaat
      121 actaccagaa gggctactgt gcctacggtg cacgctgcag atatgatcat acaaagcccc
      181 cagctgcagc aggtggagct gtgggtcctg caccccaccc ttcgccctcc tcaggcctgc
      241 atagtcctca cccttcttcc gacattgcca cgtctgttat gaggacacat tcaaatgaac
      301 ctagaaagcg ggagaagaag acgctggtgc tcagagaccg caatctcact ggtctggctg
      361 aagacaagac tcctcctcca agcacagtga ataatccagg tggctgcaat gaccctcaga
      421 ccagcccaga gatgaagccc cattcctacc tagatgccat caggactggc ctggatgact
      481 tggaggccag cagctcctac agcaacgagc agcagttgtg cccctatgct gctgctgggg
      541 aatgccggtt tggagatgcc tgtgtctatc tgcatgggga catgtgtgaa atctgcaggc
      601 ttcaagtcct ccaccccttt gacccagaac agaggaaagc tcacgagaag atgtgtatgt
      661 cgacatttga acatgagatg gaaaaggctt ttgccttcca ggcgagccag gacaaagtgt
      721 gcagtatctg tatggaggtg atcctagaga aagcctctgc ttctgagagg aggtttggca
      781 ttctctccaa ctgcagccac acctactgcc tgtcctgcat ccgtcaatgg agatgtgcca
      841 agcagtttga aaaccccatc atcaagtctt gtccagagtg ccgtgtgata tcagagtttg
      901 taattccaag tgtgtattgg gtagaagatc agaataaaaa gaatgaatta attgaagctt
      961 ttaaacaggg aatggggaaa aaggcatgta aatactttga acaaggcaag gggacctgtc
     1021 cctttggaag caagtgcctt taccgccatg cttaccctga tgggcggctg gcagagccag
     1081 agaaacctcg gaagcagcta agttctgaag gcactgtgag gttctttaac tcagtgcggc
     1141 tttgggattt tatcgagaac cgagaaaccc ggcaagtccc cagcactgat gatgtggatg
     1201 tgacggagct aggagacctc ttcatgcacc tttctggagt agagtcatca gaaccctagt
     1261 cagtgccttc atttgggctc tgcagtcaac tttccaaggc gtggtgtgga cgcatctgtc
     1321 actgacccga ggtgatgtgg taccggggtg tgagtgcagt agtgagtccc cttggtctct
     1381 tcatgatgaa atttccctgc cctggtgaag ggaagggaga tcaccaagtc catggaatca
     1441 ctacatttag atttgagagc tctgagttgt acctccagcc cctttatcag ggaccagcta
     1501 tgtggtccag ctgttttaat tgattgcttc taaatgaaac ccgactacca tctttctttt
     1561 gtgactttct tctttaagca acagtaaact taacagctgc tcctaaagca gcaaatcttt
     1621 cttgccaaga catcgccaac cctatagagg actcccgtgc agtgaccatc tctaatatag
     1681 ttgttgatcc ttgaatttat gcagctgtat agtgagaaca catttggtca tattggtgct
     1741 gtaccataga gtacttttaa ggctgtgagg atggctattg cattccgtcc agtgtctcaa
     1801 gtcaacaggc gtgtgcagtt gtaaagatct ccagggagat tccaccttcc cttcccccta
     1861 gtagttagag cacaagacac aggactcaca ctcacattgc ttgttctcac ctaaaagcag
     1921 gctatactct acactggtag acaggagcag tgactcctct ctgtctaagg agaactgggg
     1981 ccaaggcaga gcaagtttgt tttaaacctg attttatttt tgtaaaaagc tgttattacc
     2041 tgtgtgcttt ttgcttggtt gttcatgtaa ctgcagagga agatccttga gttctgcaca
     2101 agaaactgaa caagtagggc ccacactgca aatttcatat tacttttgaa ggagtcagta
     2161 gccattaaac ctaaatttaa tttattttat taaaataaca taattgagga aaaaaaaaaa
     2221 aaaaaaaaaa aaaa
//
