LOCUS       NM_001109284            2571 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus mitotic spindle positioning (Misp), mRNA.
ACCESSION   NM_001109284 XM_001077148 XM_576186
VERSION     NM_001109284.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2571)
  AUTHORS   Maier,B., Kirsch,M., Anderhub,S., Zentgraf,H. and Kramer,A.
  TITLE     The novel actin/focal adhesion-associated protein MISP is involved
            in mitotic spindle positioning in human cells
  JOURNAL   Cell Cycle 12 (9), 1457-1471 (2013)
   PUBMED   23574715
REFERENCE   2  (bases 1 to 2571)
  AUTHORS   Zhu,M., Settele,F., Kotak,S., Sanchez-Pulido,L., Ehret,L.,
            Ponting,C.P., Gonczy,P. and Hoffmann,I.
  TITLE     MISP is a novel Plk1 substrate required for proper spindle
            orientation and mitotic progression
  JOURNAL   J Cell Biol 200 (6), 773-787 (2013)
   PUBMED   23509069
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474029.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_576186.2, XM_001077148.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN16676784
                              [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2571
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..2571
                     /gene="Misp"
                     /note="mitotic spindle positioning"
                     /db_xref="GeneID:500797"
                     /db_xref="RGD:1595680"
     exon            1..91
                     /gene="Misp"
                     /inference="alignment:Splign:2.1.0"
     exon            92..1838
                     /gene="Misp"
                     /inference="alignment:Splign:2.1.0"
     CDS             146..2101
                     /gene="Misp"
                     /codon_start=1
                     /product="mitotic interactor and substrate of PLK1"
                     /protein_id="NP_001102754.1"
                     /db_xref="GeneID:500797"
                     /db_xref="RGD:1595680"
                     /translation="MDRVTRYPIFSKPHSARVTGLALDEDTSYTVELVGVGPEAGWSQ
                     GDLQTWSAEDQTKPDVKRVSVSSTRRAFLGQQSPRSLYWEDEDEETKAYRVDAGSNAF
                     CRQPRDLEAERWAVIQSQAVRKGGTVATLQASSDHRDPRIASHPRSSFTEEILVDTEQ
                     IDFLAARQQFLSLEKANTNPVTWSPTARETFARTPPGVDQTPKASTGPHVANGYTTSV
                     TSPMKEMTLEKTFHFHTSPAGSIRTTDDPGHQTRAESPETPKETPIEREIRLAQEREA
                     ELREQRGLGRAAGHQELIQIPSRPLLNKMSLTETPPRRDRGRPSLYVQRDMVQETQRE
                     EDHRREGLQVGRASTPDWTSQDPQPGFQRSLSSDCILSPDARAADPAPEARKVNRIPP
                     DAYQPYLGPGTPKLEFSAFGVYSKPSGVHSTEDTKATAFRNTTESPRHVSESSRRSLS
                     SKQEWSKPPGKPANGGVVKLENFHLRPLRFKVPDVPQEAETPQTWGWEVAGGPVLRLQ
                     KSQSSDLLEREVESVLRREREVAEERRNAFFPEVFSPVLDQEESHEQDSRSSSRASGI
                     TGSYSVSESPLFTPIHLHSGLVWKVEAPEDSSPPGQKTRKESWYAGINPSDGVNSEVL
                     GATRVKRHKNLLAERWEAHIYASEDEN"
     exon            1839..1972
                     /gene="Misp"
                     /inference="alignment:Splign:2.1.0"
     exon            1973..2011
                     /gene="Misp"
                     /inference="alignment:Splign:2.1.0"
     exon            2012..2571
                     /gene="Misp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagaaggctt ctcttccccg tggccactgc tgccctcagg gtgagctcct cactgggcat
       61 ctcctccagg accctgctgg cacctggaca gtgagcctgg aggtctccaa cccacagaaa
      121 gaaggtcaca cacaaactct ttgagatgga ccgagtgacc agatacccca tcttcagcaa
      181 gccccactca gcacgtgtca ccggcttggc cttggatgaa gacaccagct acaccgttga
      241 gctagtgggc gtagggcctg aggctggttg gagccagggt gatctgcaaa cctggtccgc
      301 tgaggaccag accaagccag atgtgaagag agtaagcgtg tcttccacca gacgagcctt
      361 cctggggcag cagtccccga ggtcactgta ctgggaagat gaggacgagg agacaaaagc
      421 ttaccgcgtg gatgccggca gcaatgcctt ctgcaggcag ccgagggacc tggaggccga
      481 gcgctgggca gtcatccaga gccaggcggt caggaagggt ggcacagtgg ccacactcca
      541 ggcttcatca gaccataggg accccaggat cgccagccat ccccggtctt cattcacaga
      601 ggagatcttg gtggacacgg agcaaatcga tttcctggct gctcggcagc agttcctgag
      661 tttagagaag gcaaacacaa atccggtcac gtggagcccc acagccaggg agacctttgc
      721 acgtacccca cctggcgtcg accagacccc caaggcctcc actgggcccc atgtagccaa
      781 tggctacacc acttcagtca cgtcaccaat gaaggaaatg accttggaga agactttcca
      841 tttccacact tccccagccg ggtccatccg tacaacggat gaccctggcc accagacccg
      901 agcagagtcc cctgagaccc ccaaggagac gcccatcgag agagagatca gactggccca
      961 ggagcgagag gcggaactgc gggagcagag agggcttggg cgggctgccg ggcatcaaga
     1021 gctcatacag atccccagca ggcccctgct caacaagatg agcctgacag agacaccccc
     1081 acgaagagac aggggccgcc catccctcta cgtgcagagg gacatggtgc aagaaacgca
     1141 acgagaagaa gatcatcgcc gagagggtct gcaggtgggc agggcgtcca cacctgactg
     1201 gacttcccag gaccctcagc ctgggttcca gagaagcctg agctccgact gcatcctcag
     1261 cccagatgcc cgagctgcag acccagctcc agaggcaagg aaagtcaacc ggatcccacc
     1321 agatgcctac cagccatacc tgggccctgg gacccccaaa ttagaattct cagccttcgg
     1381 agtatacagc aagccaagtg gtgtccactc cacagaggac accaaagcca cagccttccg
     1441 gaacaccaca gagtctccaa ggcatgtttc agaatcctcc agaagatctc tgagctcaaa
     1501 acaagagtgg tccaagcctc ctgggaagcc tgccaacggg ggtgttgtga aattagagaa
     1561 tttccacctg cgtccactgc gattcaaggt cccagatgtc ccccaggaag ctgagacccc
     1621 ccaaacctgg ggctgggaag tggccggagg ccctgtgttg agactacaaa agtcacagtc
     1681 atctgacctg ctggagaggg aggtggagag cgtcctgcgg agggagcgag aggtagctga
     1741 agagcggagg aatgccttct tcccagaggt attctcccca gtgctggacc aggaagagag
     1801 ccatgagcaa gactcccgca gttcctctcg ggcatctggc atcaccggca gctattccgt
     1861 gtcagaatca ccattattca cgcccattca cctgcattcc ggcctggtgt ggaaggtgga
     1921 ggccccagag gacagttctc cgccagggca gaagactaga aaggagtcgt ggtatgcagg
     1981 tatcaacccc tcagacggtg tcaactcgga ggtcctggga gccacgaggg taaagcgaca
     2041 caagaacctc ttggcggaac gctgggaagc acatatctat gccagcgagg atgagaactg
     2101 aggctagaag cagggacgcc cattccccgt cccacccagt cctgtggaag ctgccaggcc
     2161 tgcccaagtc tccgccgtca ggtccctatt taaacaggcc caggccgatg tttgtggcct
     2221 gcagttggct tggttttcct gaggtgggcg agtgtttcct gcttaggggt gattctcaac
     2281 tgaggctgaa gatgatccgg ccaggcctct atgtagcgaa gacttcccca aatgttccag
     2341 ggtttgggga ggtagcaagg ctgccctccg tgggatggga ggccctggga ggtgtggctc
     2401 cagagccccc acttacatcc ctcagcccct gagcaaagtg cagagccttg gatctgtcac
     2461 aatgcggaaa gaaggctctg tttagggacc cgccagtcct gtcttgccga ccccaggcac
     2521 aacacgtacc ccttcatgtt tatttgtgaa ataaatctgt cctcagcagc c
//
