LOCUS       NM_001127523            1099 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus MIS18 kinetochore protein A (Mis18a), mRNA.
ACCESSION   NM_001127523 XM_001073196 XM_221670
VERSION     NM_001127523.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1099)
  AUTHORS   Hasson,S.A., Kane,L.A., Yamano,K., Huang,C.H., Sliter,D.A.,
            Buehler,E., Wang,C., Heman-Ackah,S.M., Hessa,T., Guha,R.,
            Martin,S.E. and Youle,R.J.
  TITLE     High-content genome-wide RNAi screens identify regulators of parkin
            upstream of mitophagy
  JOURNAL   Nature 504 (7479), 291-295 (2013)
   PUBMED   24270810
REFERENCE   2  (bases 1 to 1099)
  AUTHORS   Kim,I.S., Lee,M., Park,K.C., Jeon,Y., Park,J.H., Hwang,E.J.,
            Jeon,T.I., Ko,S., Lee,H., Baek,S.H. and Kim,K.I.
  TITLE     Roles of Mis18alpha in epigenetic regulation of centromeric
            chromatin and CENP-A loading
  JOURNAL   Mol Cell 46 (3), 260-273 (2012)
   PUBMED   22516971
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC167102.1.
            
            On Jun 1, 2008 this sequence version replaced NM_001127523.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC167102.1, DY316597.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1099
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q11"
     gene            1..1099
                     /gene="Mis18a"
                     /gene_synonym="RGD1310778"
                     /note="MIS18 kinetochore protein A"
                     /db_xref="GeneID:288272"
                     /db_xref="RGD:1310778"
     exon            1..330
                     /gene="Mis18a"
                     /gene_synonym="RGD1310778"
                     /inference="alignment:Splign:2.1.0"
     CDS             24..695
                     /gene="Mis18a"
                     /gene_synonym="RGD1310778"
                     /codon_start=1
                     /product="protein Mis18-alpha"
                     /protein_id="NP_001120995.2"
                     /db_xref="GeneID:288272"
                     /db_xref="RGD:1310778"
                     /translation="MAGTFSLEPCSTSSSCNHQGKRSESSLLEKRLSEDSSRHWRLQK
                     WASMSSADASRTLLERREEKAAAAENPLVFLCTRCRRPLGDSLTWVASQEDTNCILLR
                     SVSSNVSVDKEQKLSKCRDEDGCILETLYCSGCSLSLGYVYRCTPKNLDYKRNLFCLS
                     VEAVESYTLGSSEQQIVSEEEFFNLESRVEIEKSIKQMEDVLTVMQAKLWEVESKLSK
                     AGRYS"
     exon            331..397
                     /gene="Mis18a"
                     /gene_synonym="RGD1310778"
                     /inference="alignment:Splign:2.1.0"
     exon            398..520
                     /gene="Mis18a"
                     /gene_synonym="RGD1310778"
                     /inference="alignment:Splign:2.1.0"
     exon            521..614
                     /gene="Mis18a"
                     /gene_synonym="RGD1310778"
                     /inference="alignment:Splign:2.1.0"
     exon            615..1099
                     /gene="Mis18a"
                     /gene_synonym="RGD1310778"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctccggggcg cggcaaattc gtcatggctg gtacattttc tctggaaccc tgctctacct
       61 ctagttcgtg taaccaccag ggcaagcgga gcgagtcttc gctgctggag aagcggctgt
      121 cggaagattc gagccgccat tggcggctgc agaagtgggc gagcatgtcg agcgcagacg
      181 cgtcgaggac actgctggag aggcgtgagg agaaggctgc cgcggcggag aacccgctgg
      241 tgttcctgtg tacgcgctgt cgccggccgc tgggcgactc gctcacctgg gtggctagcc
      301 aggaggacac caactgcatc ctgttgcgca gtgtctcctc taacgtctct gtggataagg
      361 aacagaaact gtccaagtgc agagatgaag atggttgcat ccttgagacg ttgtactgtt
      421 caggctgctc cctcagcctt ggctatgtgt acagatgcac tcccaagaac ctggattaca
      481 agaggaactt gttctgcctc agcgttgaag ccgttgaaag ttatacctta gggtcctctg
      541 aacagcaaat cgtgtcagaa gaggaatttt tcaatcttga aagcagagtt gaaatagaga
      601 agtctataaa gcagatggag gacgtcctga cagtcatgca agcgaagctg tgggaggtgg
      661 aatcaaaact gtccaaggct ggccggtaca gctgagctgg ctccgtgccc gccatggcca
      721 ccctgttcct aacatgctgt tcctctgccc ttactgtagg agaagaggta actggtgtcc
      781 ttatgtgaac tttaaagcca gttcaggata catgctggaa tgggatttgg atgttttaat
      841 tttaatataa aaaactgagg tgatttcctg tcttcttttt ctattaaata tgtgtatgtg
      901 tgtgtgtatg tatgtatgta tgtgtgtatt ttttgatctt ttaaaaactt tgttacttta
      961 aatactttga atatttaaga atagagagaa gaggggttgg ggatttagct cagcggtaga
     1021 gcgcttgcct agcaagcgca aggccctggg ttcggtcccc agctccgaaa aaaagaaaaa
     1081 aaaaaaaaaa aaaaaaaaa
//
