LOCUS       NM_019263               2383 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus multiple inositol-polyphosphate phosphatase 1
            (Minpp1), mRNA.
ACCESSION   NM_019263 XM_001079775 XM_342044
VERSION     NM_019263.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2383)
  AUTHORS   Cho,J., King,J.S., Qian,X., Harwood,A.J. and Shears,S.B.
  TITLE     Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the
            regulatory capacity of the Rapoport-Luebering glycolytic shunt
  JOURNAL   Proc Natl Acad Sci U S A 105 (16), 5998-6003 (2008)
   PUBMED   18413611
REFERENCE   2  (bases 1 to 2383)
  AUTHORS   Gimm,O., Chi,H., Dahia,P.L., Perren,A., Hinze,R., Komminoth,P.,
            Dralle,H., Reynolds,P.R. and Eng,C.
  TITLE     Somatic mutation and germline variants of MINPP1, a phosphatase
            gene located in proximity to PTEN on 10q23.3, in follicular thyroid
            carcinomas
  JOURNAL   J Clin Endocrinol Metab 86 (4), 1801-1805 (2001)
   PUBMED   11297621
REFERENCE   3  (bases 1 to 2383)
  AUTHORS   Caffrey,J.J., Hidaka,K., Matsuda,M., Hirata,M. and Shears,S.B.
  TITLE     The human and rat forms of multiple inositol polyphosphate
            phosphatase: functional homology with a histidine acid phosphatase
            up-regulated during endochondral ossification
  JOURNAL   FEBS Lett 442 (1), 99-104 (1999)
   PUBMED   9923613
REFERENCE   4  (bases 1 to 2383)
  AUTHORS   Craxton,A., Caffrey,J.J., Burkhart,W., Safrany,S.T. and Shears,S.B.
  TITLE     Molecular cloning and expression of a rat hepatic multiple inositol
            polyphosphate phosphatase
  JOURNAL   Biochem J 328 (Pt 1) (Pt 1), 75-81 (1997)
   PUBMED   9359836
REFERENCE   5  (bases 1 to 2383)
  AUTHORS   Ali,N., Craxton,A. and Shears,S.B.
  TITLE     Hepatic Ins(1,3,4,5)P4 3-phosphatase is compartmentalized inside
            endoplasmic reticulum
  JOURNAL   J Biol Chem 268 (9), 6161-6167 (1993)
   PUBMED   8384201
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF012714.2, CO388212.1 and CV120065.1.
            
            On or before Oct 28, 2007 this sequence version replaced
            XM_342044.3, XM_001079775.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF012714.2, SRR8487227.25398.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1068              AF012714.2         1-1068
            1069-1744           CO388212.1         46-721
            1745-2273           CV120065.1         154-682
            2274-2383           AF012714.2         2272-2381
FEATURES             Location/Qualifiers
     source          1..2383
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q52"
     gene            1..2383
                     /gene="Minpp1"
                     /note="multiple inositol-polyphosphate phosphatase 1"
                     /db_xref="GeneID:29688"
                     /db_xref="RGD:3089"
     CDS             1..1446
                     /gene="Minpp1"
                     /EC_number="3.1.3.62"
                     /EC_number="3.1.3.80"
                     /note="multiple inositol polyphosphate histidine
                     phosphatase 1; 2,3-BPG phosphatase;
                     2,3-bisphosphoglycerate 3-phosphatase; ins(1,3,4,5)P(4)
                     3-phosphatase; inositol (1,3,4,5)-tetrakisphosphate
                     3-phosphatase"
                     /codon_start=1
                     /product="multiple inositol polyphosphate phosphatase 1
                     precursor"
                     /protein_id="NP_062136.1"
                     /db_xref="GeneID:29688"
                     /db_xref="RGD:3089"
                     /translation="MLRGARSHLSASVALAAVLAAALLSSFARCSLPGRGDPVASVLS
                     PYFGTKTRYEDVNPWLLGDPVAPRRDPELLAGTCTPVQLVALIRHGTRYPTTKQIRKL
                     RQLQGLLQTRESVDGGSRVAAALDQWPLWYDDWMDGQLVEKGRQDMRQLALRLAALFP
                     DLFCRENYGRLRLITSSKHRCVDSSAAFLQGLWQHYHPGLPPPDVSDMECDPPRVNDK
                     LMRFFDHCEKFLTEVERNATALYHVEAFKTGPEMQTVLKKVAATLQVPVNNLNADLIQ
                     VAFFTCSFDLAIQGVHSPWCDVFDVDDAKVLEYLNDLKQYWKRSYGYAINSRSSCNLF
                     QDIFLHLDKAVEQKQRSQPVSSPVILQFGHAETLLPLLSLMGYFKDKEPLTAYNFEEQ
                     VHREFRSGHIVPYASNLIFVLYHCEDAQTPQEKFQIQMLLNEKVLPLAHSQKTVALYE
                     DLKNHYQDILQSCQTSKECNLPKVNITSDEL"
     exon            1..619
                     /gene="Minpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            620..817
                     /gene="Minpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            818..915
                     /gene="Minpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            916..1049
                     /gene="Minpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1050..2378
                     /gene="Minpp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgcttcgcg gcgcgcgcag ccacctctcg gcctcggtag ccctcgccgc ggtcctggct
       61 gcggcgctgc tctcgtcgtt cgcgcgctgc tctctcccgg ggcgcggcga cccggtggct
      121 tcggtgctta gcccctactt cggcacgaag acacgctacg aagatgtcaa cccctggctg
      181 ctgggcgacc cggtggcgcc gcgacgggac ccggagctgc tggcggggac ttgcaccccg
      241 gtgcagctgg tcgccctcat ccgtcacggc acccgctacc ctacgaccaa gcagatccgc
      301 aagctgaggc agctgcaggg gctgctgcag acccgcgagt ccgtggatgg cgggagccga
      361 gtggccgccg ctctggacca atggccgctg tggtacgatg actggatgga cgggcagctg
      421 gtggaaaagg ggcggcagga catgcgacag ctggccctgc gtctggccgc cctcttccct
      481 gacctcttct gccgggagaa ctacggccgc ctgcggctga tcaccagctc caagcaccgc
      541 tgtgtggaca gcagcgccgc cttcctccaa gggttgtggc aacattacca cccaggattg
      601 ccacctcccg acgtctcaga catggagtgt gaccctccga gagttaatga taagctaatg
      661 aggttcttcg atcactgtga gaagttttta accgaagtcg aaagaaacgc cacggctctt
      721 tatcatgtgg aagccttcaa aaccgggcca gaaatgcaga cagttttaaa gaaagttgca
      781 gccactttgc aagtgccagt gaacaattta aatgcagact taattcaggt agcctttttc
      841 acctgttcgt ttgacctggc aattcaaggt gtccattctc cctggtgcga tgtgtttgac
      901 gtagatgatg cgaaggttct ggaatactta aatgatctga aacagtactg gaaacgaagt
      961 tatggctatg ccattaacag ccggtccagc tgcaacctgt ttcaggacat ttttctacac
     1021 ctggacaaag cagttgagca gaagcaaagg tctcagccgg tctcttctcc agtcatcctc
     1081 cagtttggtc atgcggagac cctcctaccc ctgctctcgc tcatgggcta cttcaaggac
     1141 aaggagcccc tgacagcata caattttgag gagcaggtgc atcgcgagtt ccgaagtggt
     1201 cacatcgtac catatgcttc aaacctaata tttgtgcttt accattgtga agacgcacag
     1261 acccctcaag aaaaattcca gatacaaatg ctgctgaatg aaaaggtgtt acccttagct
     1321 cactcgcaga aaactgttgc cttgtatgag gatctgaaga accactacca ggacattctt
     1381 cagagctgtc aaactagtaa agaatgtaac ctacccaagg tgaacatcac gtccgacgag
     1441 ctctgaggac tcatcagtgc tctgctgagg gcgcttgttg ccaataggta gccactctaa
     1501 aggcagcaac aggaggatct ctgtgagctc aaggccaacc tgttctacat agtgagttcc
     1561 aggccagcca aggctgcgta gagaaataaa gtttggtcct tttgtctttt cacagaaaat
     1621 gatagtttct tttagaatct ggacatacgg gtaagacatg actctccctg gagcagctct
     1681 cttcagaaaa actaattcag caaaacagct gtccctccca gtgtttgcag agctgaaatt
     1741 ttcctaatga cctaagaaaa tgctgatgta gaatggtatt agaaaataac acttcaaaag
     1801 tgttggatac caaagcacag tggcagctgg gtgagccgca gtgagtgact gagatgggga
     1861 cttgagtgat catgttgggt tctttccttc tccttcacga aggacacaaa gaaggaagtc
     1921 taataacgta tccatccaga caggaaatca actcgatatt aagaaccagg ctgaagtaaa
     1981 actgaaagtg tgggctattt ttgttgatgt tatttacaaa aagatttaaa cactgtcagt
     2041 aattgccttt aacctccaag taggtcttgc agaaccacct ccatccctcg gacctgtttg
     2101 aggcgcgcag ttataatggg gcccagcctg gtacaggagc cgacttcctt gactgttgcc
     2161 tggttatctt tcgttccatc atggctcccc tttttatatc ttgatattac ataaagttta
     2221 tcttttggtg gcttggattt tttttttaaa taaagactta tctgcctaat ttaattgtag
     2281 agattcgaac ctgattcaaa gaaattttga gttctttcaa ataccataaa aatgtttgct
     2341 acaataaata aataaaattc ttgtggcttt actaccaaaa aaa
//
