LOCUS       NM_001414352            5089 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus misshapen-like kinase 1 (Mink1), transcript
            variant 1, mRNA.
ACCESSION   NM_001414352 XM_006246718
VERSION     NM_001414352.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5089)
  AUTHORS   Gloerich,M., ten Klooster,J.P., Vliem,M.J., Koorman,T.,
            Zwartkruis,F.J., Clevers,H. and Bos,J.L.
  TITLE     Rap2A links intestinal cell polarity to brush border formation
  JOURNAL   Nat Cell Biol 14 (8), 793-801 (2012)
   PUBMED   22797597
REFERENCE   2  (bases 1 to 5089)
  AUTHORS   Kaneko,S., Chen,X., Lu,P., Yao,X., Wright,T.G., Rajurkar,M.,
            Kariya,K., Mao,J., Ip,Y.T. and Xu,L.
  TITLE     Smad inhibition by the Ste20 kinase Misshapen
  JOURNAL   Proc Natl Acad Sci U S A 108 (27), 11127-11132 (2011)
   PUBMED   21690388
REFERENCE   3  (bases 1 to 5089)
  AUTHORS   Hussain,N.K., Hsin,H., Huganir,R.L. and Sheng,M.
  TITLE     MINK and TNIK differentially act on Rap2-mediated signal
            transduction to regulate neuronal structure and AMPA receptor
            function
  JOURNAL   J Neurosci 30 (44), 14786-14794 (2010)
   PUBMED   21048137
REFERENCE   4  (bases 1 to 5089)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   5  (bases 1 to 5089)
  AUTHORS   Nonaka,H., Takei,K., Umikawa,M., Oshiro,M., Kuninaka,K.,
            Bayarjargal,M., Asato,T., Yamashiro,Y., Uechi,Y., Endo,S.,
            Suzuki,T. and Kariya,K.I.
  TITLE     MINK is a Rap2 effector for phosphorylation of the postsynaptic
            scaffold protein TANC1
  JOURNAL   Biochem Biophys Res Commun 377 (2), 573-578 (2008)
   PUBMED   18930710
REFERENCE   6  (bases 1 to 5089)
  AUTHORS   McCarty,N., Paust,S., Ikizawa,K., Dan,I., Li,X. and Cantor,H.
  TITLE     Signaling by the kinase MINK is essential in the negative selection
            of autoreactive thymocytes
  JOURNAL   Nat Immunol 6 (1), 65-72 (2005)
   PUBMED   15608642
  REMARK    Erratum:[Nat Immunol. 2005 Feb;6(2):219]
REFERENCE   7  (bases 1 to 5089)
  AUTHORS   Hu,Y., Leo,C., Yu,S., Huang,B.C., Wang,H., Shen,M., Luo,Y.,
            Daniel-Issakani,S., Payan,D.G. and Xu,X.
  TITLE     Identification and functional characterization of a novel human
            misshapen/Nck interacting kinase-related kinase, hMINK beta
  JOURNAL   J Biol Chem 279 (52), 54387-54397 (2004)
   PUBMED   15469942
  REMARK    Erratum:[J Biol Chem. 2005 Feb 11;280(6):5128]
REFERENCE   8  (bases 1 to 5089)
  AUTHORS   Dan,I., Watanabe,N.M., Kobayashi,T., Yamashita-Suzuki,K.,
            Fukagaya,Y., Kajikawa,E., Kimura,W.K., Nakashima,T.M.,
            Matsumoto,K., Ninomiya-Tsuji,J. and Kusumi,A.
  TITLE     Molecular cloning of MINK, a novel member of mammalian GCK family
            kinases, which is up-regulated during postnatal mouse cerebral
            development
  JOURNAL   FEBS Lett 469 (1), 19-23 (2000)
   PUBMED   10708748
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Nov 18, 2022 this sequence version replaced XM_006246718.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760386 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-259               JAXUCZ010000010.1  55777003-55777261
            260-325             JAXUCZ010000010.1  55811117-55811182
            326-382             JAXUCZ010000010.1  55813120-55813176
            383-508             JAXUCZ010000010.1  55813260-55813385
            509-619             JAXUCZ010000010.1  55815762-55815872
            620-710             JAXUCZ010000010.1  55816107-55816197
            711-841             JAXUCZ010000010.1  55816637-55816767
            842-896             JAXUCZ010000010.1  55817165-55817219
            897-975             JAXUCZ010000010.1  55817380-55817458
            976-1151            JAXUCZ010000010.1  55817694-55817869
            1152-1221           JAXUCZ010000010.1  55818114-55818183
            1222-1432           JAXUCZ010000010.1  55818869-55819079
            1433-1549           JAXUCZ010000010.1  55821351-55821467
            1550-1636           JAXUCZ010000010.1  55821932-55822018
            1637-1891           JAXUCZ010000010.1  55822221-55822475
            1892-2065           JAXUCZ010000010.1  55822679-55822852
            2066-2329           JAXUCZ010000010.1  55823096-55823359
            2330-2415           JAXUCZ010000010.1  55823701-55823786
            2416-2526           JAXUCZ010000010.1  55823950-55824060
            2527-2645           JAXUCZ010000010.1  55824196-55824314
            2646-2734           JAXUCZ010000010.1  55824529-55824617
            2735-2898           JAXUCZ010000010.1  55824916-55825079
            2899-3004           JAXUCZ010000010.1  55825398-55825503
            3005-3142           JAXUCZ010000010.1  55825583-55825720
            3143-3251           JAXUCZ010000010.1  55825918-55826026
            3252-3419           JAXUCZ010000010.1  55826541-55826708
            3420-3563           JAXUCZ010000010.1  55826817-55826960
            3564-3698           JAXUCZ010000010.1  55827201-55827335
            3699-3799           JAXUCZ010000010.1  55827462-55827562
            3800-3949           JAXUCZ010000010.1  55827643-55827792
            3950-4109           JAXUCZ010000010.1  55827884-55828043
            4110-4249           JAXUCZ010000010.1  55828130-55828269
            4250-5089           JAXUCZ010000010.1  55828567-55829406
FEATURES             Location/Qualifiers
     source          1..5089
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..5089
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /note="misshapen-like kinase 1"
                     /db_xref="GeneID:303259"
                     /db_xref="RGD:1359135"
     exon            1..259
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     CDS             203..4333
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /EC_number="2.7.11.1"
                     /note="isoform 1 is encoded by transcript variant 1; MEK
                     kinase kinase 6; GCK family kinase MiNK;
                     misshapen/NIK-related kinase; MAPK/ERK kinase kinase
                     kinase 6; mitogen-activated protein kinase kinase kinase
                     kinase 6"
                     /codon_start=1
                     /product="misshapen-like kinase 1 isoform 1"
                     /protein_id="NP_001401281.1"
                     /db_xref="GeneID:303259"
                     /db_xref="RGD:1359135"
                     /translation="MGDPAPARSLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRH
                     VKTGQLAAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLW
                     LVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVL
                     LTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWS
                     LGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFTDFIDTCLIKTYLS
                     RPPTEQLLKFPFIRDQPTERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHG
                     EEGEPSSIMNVPGESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLH
                     QRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQE
                     YIRHRLEEEQRQLEILQQQLLQEQALLLEYKRKQLEEQRQSERLQRQLQQEHAYLKSL
                     QQQQQQQQQLQKQQQQQQQQQQQQQQQQILPGDRKPLYHYGRGINPADKPAWAREVEE
                     RARMNKQQNSPLAKTKPSSAGPEPPIPQASPSPPGPLSQTPPMQRPVEPQEGPHKSLV
                     AHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAAVPTPTATPSARGAVIRQN
                     SDPTSEGPGPSPNPPSWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRARPR
                     SNSAWQIYLQRRAERGTPKPPGPPAQPPGPPNTSSNPDLRRSDPGWERSDSVLPASHG
                     HLPQAGSLERNRNRVGASTKLDSSPVLSPGNKAKPEDHRSRPGRPADFVLLKERTLDE
                     APKPPKKAMDYSSSSEEVESSEDEEEEGDGEPSEGSRDTPGGRSDGDTDSVSTMVVHD
                     VEEVSGTQPSYGGGTMVVQRTPEEERSLLLADSNGYTNLPDVVQPSHSPTENSQGQSP
                     PTKDGGGDYQSRGLVKAPGKSSFTMFVDLGIYQPGGSGDTIPITALVGGEGGRLDQLQ
                     FDVRKGSVVNVNPTNTRAHSETPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLD
                     RSGQGKVYGLIGRRRFQQMDVLEGLNLLITISGKRNKLRVYYLSWLRNKILHNDPEVE
                     KKQGWTTVGDMEGCGHYRVVKYERIKFLVIALKNSVEVYAWAPKPYHKFMAFKSFADL
                     PHRPLLVDLTVEEGQRLKVIYGSSAGFHAVDVDSGNSYDIYIPVHIQSQITPHAIVFL
                     PNTDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPTSVAYICSNQIMGWGEKAIEI
                     RSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLNRNCIMNW"
     exon            260..325
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            326..382
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            383..508
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            509..619
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            620..710
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            711..841
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            842..896
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            897..975
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            976..1151
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            1152..1221
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            1222..1432
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            1433..1549
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            1550..1636
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            1637..1891
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            1892..2065
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            2066..2329
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            2330..2415
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            2416..2526
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            2527..2645
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            2646..2734
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            2735..2898
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            2899..3004
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            3005..3142
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            3143..3251
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            3252..3419
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            3420..3563
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            3564..3698
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            3699..3799
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            3800..3949
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            3950..4109
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            4110..4249
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
     exon            4250..5089
                     /gene="Mink1"
                     /gene_synonym="MEKKK 6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agggcagcgg gcggctcggg ttgcaggcgc gcgggtcaga gcgcctgtca gccgctgggt
       61 cggtcctccc gctggccctc cccctccccg gccttcgggg caggcgcggt ggagcccgcc
      121 cctcgggtcc cccgatgggg gagaagcggc aacggcggca gcggagtgag cgagccggag
      181 cgtgagtggc cccgcggcgg ccatgggcga cccagccccc gcccgaagct tggacgacat
      241 cgacctgtct gccctgaggg accctgcagg aatctttgag ctggtggagg tggttggcaa
      301 tggaacctat ggacaggtgt acaaggggcg gcacgtcaag actgggcagc tggctgccat
      361 taaggtcatg gatgtcacag aggatgagga ggaagaaatc aaacaggaaa tcaacatgtt
      421 aaagaagtac tctcaccatc gcaatattgc cacctactac ggggccttca tcaagaagag
      481 ccctcctggg aacgatgacc agctctggct ggtgatggag ttctgtggtg ctggctcagt
      541 gaccgacctg gtaaagaaca cgaaaggaaa cgcgctgaaa gaggattgca ttgcgtacat
      601 ctgcagggag attctcaggg gtcttgccca tctccatgcc cacaaggtga tccaccgaga
      661 tatcaaggga caaaatgtgc tgctgacaga gaatgctgaa gtcaagctag tggactttgg
      721 ggtgagtgct cagctggacc gcactgtggg gaggcggaac actttcattg ggaccccata
      781 ctggatggct ccagaagtca ttgcctgtga cgagaacccc gatgccacct atgactacag
      841 gagtgacatt tggtctctag gaatcacagc cattgaaatg gcagagggag ccccccctct
      901 gtgtgacatg caccctatgc gggctctctt cctcatccct cggaaccctc cccccaggct
      961 caagtcaaag aaatggtcta agaagttcac tgacttcatt gacacgtgtc tcatcaagac
     1021 ttacctgagc cgaccaccaa cagaacagtt actcaaattc cccttcatcc gagaccagcc
     1081 cacggagcgg caggtccgca tccagctcaa ggaccacatt gaccgctccc ggaagaagcg
     1141 gggggagaaa gaggagacag agtatgagta cagtggcagt gaagaggaag acgacagcca
     1201 tggagaggaa ggcgagccaa gttccatcat gaatgtgcct ggggagtcca cactccgccg
     1261 agaattcctc agactccaac aggagaataa gagcaactca gaggctttaa agcagcagca
     1321 gcagctgcag cagcagcagc agcgggaccc tgaggcacac atcaaacacc tgctgcacca
     1381 gcggcagcgt cgcatagagg agcagaagga ggagcggcga cgtgtagagg agcaacagcg
     1441 gcgagagcga gaacagcgca agctgcagga gaaggagcag cagcggcggt tggaagacat
     1501 gcaagccctt cgtcgagagg aagagaggcg gcaagcagag cgggaacagg aatatattcg
     1561 tcacaggcta gaggaggagc agcgacagct cgagatcctt cagcaacagc tgctccagga
     1621 acaggccttg ctgctggaat acaagcggaa gcagctggag gagcagcggc agtcggagcg
     1681 gctccagaga cagctgcagc aggagcatgc ctacctcaag tccctgcagc agcagcagca
     1741 acagcagcag cagctccaga aacaacagca gcagcagcag cagcagcagc agcagcagca
     1801 gcagcagcag atcctacctg gagacaggaa acccctgtat cattatggtc ggggcattaa
     1861 tcctgctgac aagccagcat gggcccgaga ggtggaagag agagctcgga tgaacaagca
     1921 gcagaactct cccttggcca agacaaagcc aagcagtgcg gggccagagc cccccattcc
     1981 ccaggcctct cctagccccc caggacctct ttcccaaact cctcctatgc agaggcctgt
     2041 ggagcctcag gaaggaccac acaagagcct ggtggcacac cgggtcccac tgaagccata
     2101 tgcagcacct gtaccccgat cccagtccct gcaggaccaa cccactcgaa acttggctgc
     2161 cttcccagcc tcccacgacc ctgaccctgc tgctgtcccc acacccactg ccacacccag
     2221 tgcccgagga gctgtcatcc gccagaattc agaccccacc tctgaagggc ctgggcctag
     2281 ccctaaccct ccatcctggg tccggcctga taatgaagct ccacccaagg ttcctcagag
     2341 gacctcgtct attgccactg cccttaacac cagtggggct ggagggtccc ggccagctca
     2401 ggctgtccgt gccagacctc gcagcaactc cgcctggcaa atctatctgc agaggcgggc
     2461 agagcgaggc acccccaagc ctcctgggcc cccagctcag ccccctggcc cgcccaacac
     2521 ctctagtaac cctgacctca ggaggagtga ccctggctgg gagcgttcag acagtgtcct
     2581 ccctgcctcc cacggccacc tccctcaggc cggctccttg gagcggaacc gaaaccgtgt
     2641 gggagcctcc acaaaactgg acagctcccc agtgctctcc cctgggaaca aggccaagcc
     2701 tgaagaccac cgctcaaggc caggccggcc cgcagatttc gtgttgctca aagagcggac
     2761 tctggatgag gcccctaagc ctcccaagaa ggccatggac tattcctcat ccagtgagga
     2821 ggtggagagc agtgaagatg aggaggagga aggcgatggg gagccatcag aggggagcag
     2881 agacactccc gggggccgca gtgatggtga cacagatagc gtcagcacca tggtggttca
     2941 tgatgttgaa gaggtatccg ggacccagcc ttcatatgga ggaggcacca tggtggtcca
     3001 gcgtactcct gaagaggagc gaagcctgct gcttgctgat agcaatggct acacaaacct
     3061 gccagatgtg gtccagccca gccactcacc tactgagaac agccaaggtc aaagccctcc
     3121 aacaaaggat ggaggcggtg attaccagtc tcgtgggctg gtaaaggccc caggaaagag
     3181 ttcattcacc atgtttgtgg atctagggat ctaccagcct ggaggcagtg gggataccat
     3241 ccccatcaca gccctagtgg gcggagaggg tggtcgcctt gatcaactgc agttcgatgt
     3301 gaggaagggc tctgtggtca acgtcaatcc caccaacact cgagctcata gtgaaactcc
     3361 cgagattcgc aagtacaaga agcgattcaa ttccgagatc ctctgtgcag ccctctgggg
     3421 ggtcaacctc ctagtgggca cagagaatgg gctgatgttg ctggaccgaa gtgggcaggg
     3481 caaagtgtat ggacttattg ggcgacgacg cttccagcaa atggatgttc tggaagggct
     3541 caacctgctc atcaccatct cagggaaaag gaacaaactg cgggtatatt acctgtcctg
     3601 gcttcggaat aagattctac acaatgaccc agaggtggaa aagaagcagg ggtggaccac
     3661 cgtgggggac atggagggct gcggccacta tcgtgttgtg aaatatgaac gaattaagtt
     3721 cctggtcatt gctctgaaga actctgtgga ggtgtatgcc tgggccccta aaccctacca
     3781 caaattcatg gccttcaagt cctttgctga cctccctcac cgccctctgc tggtggacct
     3841 gacagtagag gagggccagc ggctcaaggt catctatggc tccagtgctg gcttccatgc
     3901 tgtggatgtt gactctggga acagctatga catctacatc cctgtacata tccagagcca
     3961 aatcacaccc cacgccatcg tctttctccc caacactgac ggcatggaga tgctgctttg
     4021 ctatgaagat gagggtgtct acgtcaacac ttacgggcgg atcatcaagg acgtggtgct
     4081 gcagtgggga gagatgccca cctctgtcgc ctacatctgc tccaaccaga taatgggctg
     4141 gggtgagaag gccatagaga tccgctctgt ggagacaggc cacctagatg gggtcttcat
     4201 gcacaaacga gcccagaggc tcaagttcct gtgtgagcgg aatgataagg tgttttttgc
     4261 ctcagtccgc tctggaggaa gcagccaagt ttactttatg actctgaacc gtaactgcat
     4321 catgaactgg tgacgaggcc cctgggctgg ggctccccac atggacccag ctctgtcccc
     4381 acagccagac tacccaggcc gcccctgccc tcccaccccc cttgggcttt tgcttttaat
     4441 ggtttgattc actggagcct gctgggaacg tgacctcata ttcctgaagc ttttgtgatc
     4501 acgtgaccat cctttctccc gacattctca aaactgcctt tccttaactt ctgggggatg
     4561 acacagcttc cttcccctta ccaggaattg agtgggactt gctcctccct tttctctaca
     4621 gaagagagtg cttggggctt ggacccctta ccccattgct gctgactgag cagggccctg
     4681 accccttttt tgcacgccag gggagccggc tccccccttg aatgtaccag actctggggg
     4741 gggtattcac tgggccctgg gttggggggg gtcaccagcc actccagggg cagggaccat
     4801 ttcctcattt ctgaaagcac tttaatgatt tcccccctca gtccccaggg aatggaggag
     4861 ggaccccata gccaaaacat tccccccttt cctccccacc cccaccccat ctttcctctt
     4921 cccttcccta gagggagagg gctcagagct cccaccctct atcctccctt gcttgcatct
     4981 gtatatagtg tgagcagcaa gtagcccttc tccctcctgt atcctttctc aatgtagtgg
     5041 ccttggatat cccctttgtt aataaagaca attcaaccag cttccacca
//
