LOCUS       NM_001106122            2321 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus MINDY lysine 48 deubiquitinase 3 (Mindy3), mRNA.
ACCESSION   NM_001106122 XM_001072337 XM_214513
VERSION     NM_001106122.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2321)
  AUTHORS   Abdul Rehman SA, Kristariyanto YA, Choi SY, Nkosi PJ, Weidlich S,
            Labib K, Hofmann K and Kulathu Y.
  TITLE     MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally
            Distinct New Family of Deubiquitinating Enzymes
  JOURNAL   Mol Cell 63 (1), 146-155 (2016)
   PUBMED   27292798
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473990.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001072337.1, XM_214513.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2321
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17q12.3"
     gene            1..2321
                     /gene="Mindy3"
                     /gene_synonym="Fam188a; RGD1309605"
                     /note="MINDY lysine 48 deubiquitinase 3"
                     /db_xref="GeneID:291320"
                     /db_xref="RGD:1309605"
     exon            1..281
                     /gene="Mindy3"
                     /gene_synonym="Fam188a; RGD1309605"
                     /inference="alignment:Splign:2.1.0"
     CDS             188..1522
                     /gene="Mindy3"
                     /gene_synonym="Fam188a; RGD1309605"
                     /EC_number="3.4.19.12"
                     /note="protein FAM188A; family with sequence similarity
                     188, member A"
                     /codon_start=1
                     /product="ubiquitin carboxyl-terminal hydrolase MINDY-3"
                     /protein_id="NP_001099592.1"
                     /db_xref="GeneID:291320"
                     /db_xref="RGD:1309605"
                     /translation="MSEVTKELLELVWGTKSSPGLSDTIFCRWTQGFVFSDSEGSALE
                     QFEGGPCAVIAPVQAFLLKKLLFSSEKSSWRDCSEDEQKELLCHTLCDILESACDSSG
                     SYCMVSWLRGRTTEDAARISGSPAQSSCQVGHSSALAVEELGFERFHALIQKRSFRTV
                     SELKDAVLDQYSMWGNKFGVLLFLYSVLLTKGIENIKNSIEDANEPLIDPVYGHGSQS
                     LINLLLTGHAVSNVWDGDRECSGMQLLGIHEQATVGFLTLMEALRYCKVGSYLKSPKF
                     PIWIVGSETHLTVFFAKDMALVAPEAPSEQARRVFQTYDPEDNGFIADTLLEDVMKAL
                     DLVSDPEYINLMKNKLDPEGLGIILLGPFLQEFFPDQGSSGPESFTVYHYNGLKQSNY
                     NEKVMYVEGTAVVMGFEDPMLQTDDTPIKRCLQTKWPYIELLWTTDRSPSLN"
     exon            282..361
                     /gene="Mindy3"
                     /gene_synonym="Fam188a; RGD1309605"
                     /inference="alignment:Splign:2.1.0"
     exon            362..422
                     /gene="Mindy3"
                     /gene_synonym="Fam188a; RGD1309605"
                     /inference="alignment:Splign:2.1.0"
     exon            423..593
                     /gene="Mindy3"
                     /gene_synonym="Fam188a; RGD1309605"
                     /inference="alignment:Splign:2.1.0"
     exon            594..645
                     /gene="Mindy3"
                     /gene_synonym="Fam188a; RGD1309605"
                     /inference="alignment:Splign:2.1.0"
     exon            646..760
                     /gene="Mindy3"
                     /gene_synonym="Fam188a; RGD1309605"
                     /inference="alignment:Splign:2.1.0"
     exon            761..834
                     /gene="Mindy3"
                     /gene_synonym="Fam188a; RGD1309605"
                     /inference="alignment:Splign:2.1.0"
     exon            835..914
                     /gene="Mindy3"
                     /gene_synonym="Fam188a; RGD1309605"
                     /inference="alignment:Splign:2.1.0"
     exon            915..985
                     /gene="Mindy3"
                     /gene_synonym="Fam188a; RGD1309605"
                     /inference="alignment:Splign:2.1.0"
     exon            986..1066
                     /gene="Mindy3"
                     /gene_synonym="Fam188a; RGD1309605"
                     /inference="alignment:Splign:2.1.0"
     exon            1067..1139
                     /gene="Mindy3"
                     /gene_synonym="Fam188a; RGD1309605"
                     /inference="alignment:Splign:2.1.0"
     exon            1140..1212
                     /gene="Mindy3"
                     /gene_synonym="Fam188a; RGD1309605"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..1300
                     /gene="Mindy3"
                     /gene_synonym="Fam188a; RGD1309605"
                     /inference="alignment:Splign:2.1.0"
     exon            1301..1372
                     /gene="Mindy3"
                     /gene_synonym="Fam188a; RGD1309605"
                     /inference="alignment:Splign:2.1.0"
     exon            1373..2321
                     /gene="Mindy3"
                     /gene_synonym="Fam188a; RGD1309605"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcctagttgc ggcttcgccc ggcttgacag gcgctgtctc tgcgggcacc gagctacact
       61 catcccgctc ggcctcccaa tcgcgcctcg gccgccgccg tcccgctgcc cttttctcaa
      121 gccttccctt ccctatgttc cgggaccgga gtacgggaag caaagaccct cttgtccagt
      181 ccccatcatg tccgaagtga ccaaagagct gctggagctg gtgtggggca ccaagagcag
      241 tcccggactg tcggacacca tcttctgccg ctggacgcaa gggtttgtgt ttagtgactc
      301 agagggatct gcattagagc agtttgaagg tggcccctgt gctgttattg cacctgttca
      361 ggcatttctt ttgaagaagc ttctgttttc ctccgagaag tcgtcctggc gggattgctc
      421 agaggacgag cagaaggagc tcctttgtca taccttgtgt gatattttag aaagtgcttg
      481 tgacagctct ggatcatact gcatggtttc atggttgaga ggaaggacga ctgaggacgc
      541 cgctaggatt tctgggagtc ctgcacagtc tagttgccaa gtgggacatt cttctgcctt
      601 ggctgtcgaa gagcttggct ttgagcgatt tcatgcatta attcaaaaaa gatcattcag
      661 aactgtatca gaattaaaag atgctgtctt ggaccagtat tcaatgtggg gaaacaaatt
      721 tggagtcttg ctttttctct attctgtatt actgacaaag ggcattgaaa acataaagaa
      781 ttcaattgaa gatgcaaacg agcctttgat agaccctgtg tacgggcatg gcagccaaag
      841 cttaataaac ctcctcctga cggggcacgc ggtctctaac gtgtgggatg gcgatagaga
      901 gtgctcagga atgcaacttc tcggtatcca tgaacaagca actgtaggat tcttaacact
      961 aatggaagct ttacgctatt gtaaggttgg ttcttacttg aaatctccaa aattccctat
     1021 ttggattgtt ggcagcgaaa ctcacctcac cgtatttttt gccaaggata tggctttagt
     1081 tgcccctgaa gcgccttcgg aacaagccag aagagttttt cagacctatg acccagaaga
     1141 taatggattc atagccgaca cacttctaga ggatgtcatg aaagccttgg accttgtttc
     1201 agatcccgag tatataaatc tcatgaagaa caaattggat ccagaaggat taggaatcat
     1261 attgttgggt ccatttcttc aagaattttt tcctgaccag ggctccagtg gtccagaatc
     1321 ttttactgtc taccactaca atggattgaa gcagtcaaat tataatgaaa aggtaatgta
     1381 tgtggaaggg actgcagtgg ttatgggttt tgaagacccc atgctacaga cagacgacac
     1441 tcctattaaa cgctgtctgc aaaccaaatg gccgtacatt gagttactgt ggaccacaga
     1501 ccgctctcct tcactcaact gagttgcccg agtattagta aggaagattg tcaaacccgg
     1561 tgttgaaagg gggattcatg actggctaca tgaagctaaa cgctggtatt gttgattaac
     1621 tgtaaataac aattaaaaac acattttcag tgtttaagat atgtttaaat tatttgttct
     1681 aaagctttat gttaaaggtt atcctatttt aatcctttct gtgaaattta ctaacaaaat
     1741 taagctttaa ttaaagttca tctcttctgc agtcaggtaa ttggtcgtta ccagattata
     1801 aacacaatat tatagcattt ttataatgac atcagtcaca aaaacctgcc tggagtatca
     1861 ttccattcat ttcattttac tgtagtattt ttagcagcct ccataccaaa atgcaaaggt
     1921 taatttttgt taattttttt tttcattgct taaatctgtt tttccatcac aaatactaat
     1981 aaatcacaaa ttattggccc tgatcctttg gtaacaaatt tgacactagc atgtttacaa
     2041 acaaataaga aaggataata tgtgggagct tctttgtgtt cacaggtgca cagggatgtg
     2101 gttttacagt gatgggggaa gaatgtgttg gctgggtggt cttacactgt cgctgtgact
     2161 gtaccgctca atacacttct ccaccttcat tcctacaagc cagctctctt gtatgtttat
     2221 aagcgtggta atgcatgaaa acatctgctg ttacattagc atattgcatt atttattatg
     2281 gccccagtta ataccataaa taaagacttt tctttaacta c
//
