LOCUS       XM_343420               7798 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus MINDY lysine 48 deubiquitinase 2
            (Mindy2), transcript variant X1, mRNA.
ACCESSION   XM_343420
VERSION     XM_343420.10
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051343.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_343420.11.
            
            On Jan 21, 2021 this sequence version replaced XM_343420.9.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7798
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..7798
                     /gene="Mindy2"
                     /note="MINDY lysine 48 deubiquitinase 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 50 ESTs, 1 long SRA read, 12 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 231 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:363089"
                     /db_xref="RGD:1311456"
     CDS             1..1800
                     /gene="Mindy2"
                     /codon_start=1
                     /product="ubiquitin carboxyl-terminal hydrolase MINDY-2
                     isoform X1"
                     /protein_id="XP_343421.3"
                     /db_xref="GeneID:363089"
                     /db_xref="RGD:1311456"
                     /translation="MENGPDSPQPLELGVPAGRVSTPEGRRRDGREAEDGPAGRAVDS
                     GGQGAAAARSSLGDPTSPSQHGCSAGSDLKNSASSSPVASEAPSRGQHKVTASPELAE
                     AAAGRGSGPVGDTGTCRVEQAAEEPSSAGALSSSCSEPSPPGDSPSLDSLESFSNLHS
                     FPSSSEFNSEEGAETRVPEDVEEGAAEPPRVAPLCKEEEEDPAQVLAASKERFPGQSV
                     YHIKWIQWKEENTPIITQNENGPCPLLAILNVLLLAWKVKLPPMMEIITAEQLMEYLG
                     DYMLEAKPKEISEIQRVNYEQNMSDAMAILHKLQTGLDVNVRFTGVRVFEYTPECIVF
                     DLLDIPLYHGWLVDPQIDDIVRAVGNCSYNQLVEKIISCKQSDNSQLVSEGFVAEQFL
                     NNTATQLTYHGLCELTSTVQEGELCVFFRNNHFSTMTKYKGQLYLLVTDQGFLTEEKI
                     VWESLHNVDGDGNFCDSEFRLRPPSDPETVYKGQQDQIDQDYLMALSLQQEQQSQDIN
                     WEQIPEGISDLELAKKLQEEEDRRASQYYQEQEQAQAAVATTTPSTQAQQGQPAQASP
                     SSIKQPGNSERKRKEPREKDKEKEKEKNSCVIL"
ORIGIN      
        1 atggagaacg gccctgacag cccacagcct ttggaactcg gggtgccagc ggggcgagtg
       61 tcaacgccgg aagggcgacg gcgcgacggg cgcgaggctg aggatggtcc cgctggacga
      121 gcggtggaca gcggcgggca gggggcggcg gcagcgcgta gcagtctcgg ggacccgacg
      181 tctccctcgc agcacggatg cagcgcgggc tcggacttga agaacagcgc gtcgtcgagc
      241 ccggtcgcct cggaggcgcc ttcaagaggg cagcacaagg tgaccgcctc cccggagctg
      301 gccgaggccg cggcgggccg agggtccggg ccagtgggtg acacaggcac ctgcagggtg
      361 gagcaggcgg cggaggagcc cagcagcgct ggcgccctga gcagcagctg cagcgagccg
      421 agcccccctg gggactcgcc tagcttggac tccctggagt ctttctccaa cctgcattct
      481 ttccccagta gctctgagtt caatagcgag gagggagcgg agaccagggt ccccgaggac
      541 gtggaggagg gcgcggcgga gccgcccagg gttgcacctc tgtgcaaaga ggaggaggag
      601 gacccggctc aggtgctggc agcctccaaa gaacgctttc cgggacagtc agtgtatcac
      661 atcaaatgga tccagtggaa agaggagaac acgcccatca tcacccagaa tgagaatgga
      721 ccctgcccat tgctggctat cctcaatgtt ttgcttctcg cctggaaggt gaaactccca
      781 ccgatgatgg agatcataac cgcggagcag ctgatggagt atctcggcga ttacatgctt
      841 gaggcaaagc caaaagaaat ctcagaaatt caacgtgtaa attatgaaca gaatatgagc
      901 gatgctatgg caatcttgca caaactgcag acaggcctgg atgtgaatgt caggttcact
      961 ggggtacgag ttttcgagta cacaccagag tgcatagtct ttgatcttct agatattcct
     1021 ttgtatcatg ggtggttagt ggaccctcag atcgatgaca ttgtaagagc tgttggcaac
     1081 tgcagctaca accagctggt ggagaagatc atctcctgta agcagtcgga caacagccag
     1141 ttggttagtg aaggctttgt agctgagcag tttctaaaca atacagccac tcaactgacg
     1201 taccatggat tatgtgaact gacttcaacg gttcaggaag gagaactctg tgtgttcttt
     1261 cggaataatc attttagcac catgacaaaa tacaagggtc aactgtattt gttggtaaca
     1321 gaccagggct ttcttactga agaaaaaatt gtctgggaaa gcctccacaa tgtagatggc
     1381 gatggaaatt tctgtgactc agaattccgt cttcggcctc cttcagatcc tgagactgta
     1441 tacaaaggtc aacaagacca aatagatcaa gactacctta tggcactgtc actgcaacaa
     1501 gaacagcaga gccaagacat caactgggag caaatcccag aaggaatcag tgacttggag
     1561 ttggcaaaga aactccagga agaggaggac cgacgggcct ctcagtacta ccaggagcag
     1621 gagcaggctc aggctgctgt ggccaccacc accccttcca cgcaggccca gcagggccag
     1681 ccagcgcaag cctctccatc aagtataaaa cagcctggga atagtgaacg gaaacgcaag
     1741 gaacctcggg aaaaagacaa agagaaagaa aaggaaaaaa atagctgcgt gattttgtag
     1801 ggattgctgg catctgtggg aaccacctat gcagatgacg gaaaggaaga cccagtacct
     1861 accgtctgtg cctgatctcc caatggattt tgctcatgtt ttccagggga aagttgttac
     1921 tttgttacaa tcaacttttt caagttacac aatacattct ttatgagctg gagttttatg
     1981 ttacaagttg gaactgttgt gtgttgtcac tgtagccaaa tgagtatatc actcctattt
     2041 tgtgtctagt gacattgcaa ctcaatcagt tagtaagcta ctgtgttcta tgtgacaatg
     2101 gatggaggtc actgaatgag tttgatcctt ctcaagatgt aattattagc acaactatgt
     2161 ctgaacttta cattgttaaa ttatgttcta atccatgagg aaaaaggagt ttaatactgg
     2221 ggaggggcag caggaataat gacccttcat tgtgcattga actggttcag cccttgaaca
     2281 gctttacctg tctttagtaa tgcacatctt agctattatc ttgggaactg ataatggagc
     2341 ttggatccaa tttagataga aaaatatttt ttattttcca atagcaaaaa aataaaatac
     2401 acgacactaa tacttataac ctattcagat gagatgctga ctttgtagtg ctatgaggtg
     2461 ttgagaaatt tcagcacctt cagagcctga aaggtggctt ctgtttgatg aggatgtaat
     2521 acgtgagtga ggagaagacc acactcatgt tcagccttgt aaatataagg acagagaaga
     2581 gcagagttca ctgtctacct ttttctagaa ttaccttgaa ccttaaattt taaatcatgt
     2641 ttattgctag aaatttaaac caataaaaag cacatttctg aaggagagtt aatctcttga
     2701 ctctaatgaa aagatattaa taaaattcta aacataggta ggagtctgaa ggaatttatg
     2761 taaaagcaat cagatttttt aacttatgag aaccaaatga acctaagaca ccttacatca
     2821 tttctaggat tcggggatat ttactcagcc tggcgatgag gcagcacata ctgtatttct
     2881 agatacaatt tggaaaactg tccttcacat gctttatata ctttgtattt agactttgtt
     2941 tcagttattt ttaaagatta ttgccagtgc acaaagctgc gtgatttatc ctaaacctca
     3001 gtaaatttta ttcaggagca tcacagattg aaaatccagt tagagaatat ttcttgtggt
     3061 ctggaagcaa cgaaagacta ccaaaagaaa gaagtctaga gttgaagact actgtcattg
     3121 atgttttcca tgatcccaag ccggctgtag gctgagtaca tatgtaaaaa gtagagtttt
     3181 atttatgaaa agtcttgttc taagaggaaa agaacttcag ggccacgctg tacctttctg
     3241 tccttctata gtacctatct atttatgccc tttgttgttt ctttagactt tctatactag
     3301 catggggacg aatcagagga cctgcctggg gtataacatt tgtgtgtaaa atacctgata
     3361 agtctcttaa gtgcaaccta gagtgagtac gaactgtcag agaccagacc ccttcagatg
     3421 gactgacctc agcataaaca cccatgacag cattctgctg attggaggag aaaacgcaaa
     3481 cctcagagtt tgcctttccc agatcagtct aatgttttag tttaggaaac agttaaccta
     3541 agagatcaag gcatattttt ccacaattat attacaatat ctacttattg cccttgaaga
     3601 tctatatata aaagttgtgt tattttttac tctcatattt ttccaaagat aataactgcc
     3661 aatactatgt tccctttaga agaaggaaga aatagaacag aaggaacaca caccactcac
     3721 tgaaaaccat cagcgctgct gtcagaggag tggatgtgtg cttaaaatca gcagtgtact
     3781 gttcgtcaat ccaaactgtt cttacatgag gttcccgagt tgggcttggc tacattcctg
     3841 gaatttagtt tgatatgaca agagtcatat caaacttatt ataagatgtt tgttttgatt
     3901 actgtgggag aggttaaatg tttgactcta ttaaaacaaa tctctaagat atgattcctg
     3961 tccttgaagg cttgtcaagg ttccaaactg ccacgtattt atttcctgtg tttgctcaag
     4021 gcagcaagtg atcaatattc aggcatatta ctgcttgttt gggcaaagag gactttgaaa
     4081 atggtgtttt gagggatttt cccccttaca atactttgtg atattgacat tgttatacat
     4141 atattgctaa cacacgttac agtttaaaca ttttggagct taatgattct aaattctggg
     4201 cacacttgac tcatgtgcca gtacagcggg agagctagca gaaggcaggc agggagcaga
     4261 tatggtccct ggcacttttc tcatacattc agagcacact agtaaggtta gtgaccagtc
     4321 tgtattaatg tgcacttctt cattagtaag tctgttgcgt caacaatgct gtgacctgta
     4381 ctagtttatc agtacctaga atcgtgtgta tgtctccatg acttctgttt aggcctcaaa
     4441 gcaatctgaa aactaacaga tttaaaagtt gtgaatattt aaaaatattc acacacacct
     4501 aggagtatca ccaagtggta cagcatttgc ctgcagcaca caaaaccctg ggttcaattc
     4561 ctagcataag tatgtagact cactggcagc taatcagggc actggcctta tgcccagtca
     4621 gtgtggatgg gaagaataac atcctccatg tctcaaggtc aggctaggat tgagcaagtc
     4681 agaagcttaa gttcagaatt aggttctaga agatgtaata atatatatac tataatgtca
     4741 gatgttagtt gactaaactc aatgttaggc actctgtact tgcacaaaaa cttcatagca
     4801 tttgctttcc ctaaatcata aactcatttc agacctggag gaccagagag catacgtgag
     4861 ggaaaggcat gactgtgatc acaaatgtct gtaaaatcct agcaaattag gcaagaattt
     4921 ctagaactgt cctcaatctt acttaaattt tagacatagt cttgctatat ctagccagac
     4981 tggcttggaa tcgactgttg tagcccaggc taccttcaaa cccacaatcc tcctgcccca
     5041 gcttctcact gccactacta caggtggata tcaccatacc cagcttgttg aaacttcctt
     5101 tagaaaagca aacagcaaac tgattacatg ttgctttgtg attcattgta ctggttattt
     5161 attttttgac agaaagctta cagccttgta cctaacactg tcttagacat ataaattgaa
     5221 aaattaatgt ttgacaaaat aaggcagaga cattaaagat agccacttat ttatatttta
     5281 aggaattaga cacgtgaaat tctggctcat ttggtgttcg aaacctgact ttatcagggc
     5341 atggtaatac atacctgtca tagcgttttg tagggctaaa gcaggaggat tctaagttca
     5401 aggccactct gtgcaaataa taagaccctg attctaaaac caaacctgac tttgtcttgt
     5461 tttggcaatc attgtgtgcc tctgtttact ctgtgcaggg tgctcctctt cccatgtatg
     5521 cccacagtgc ttggttctcc tgagaaaagg ccatacttta gcactgagaa ttaccgagat
     5581 catcacagac actgcacatt ctccattctc gagtgtgaag actttttata atgacttaaa
     5641 tcagtttttt atgctgttag aatgtgtagg attcctttga atgtggcatc ctggctttca
     5701 aaaatatttt ttgcagctgc ttttctattc agcaggctag tgttgagacc aggagtgttt
     5761 gggcttacaa aatgcacttc acagacctgt ctttccagta tcctccacag atctagcttt
     5821 tagagcccct tgctcagtcc ctccagggta gagcaatatc aggaactgac tttgctctcc
     5881 ccactgttgt cagtgtatac agcttatttg tggctttaaa tgaactctga tcttgtgcaa
     5941 gtcaaatcct ttagacagca agtgaaaaaa ccctaaagga ccatgtgtga accttagcgt
     6001 ccgtggttct tgataagtta gcatcttttg ttactgatgc ttgacatttt tgaaactgtt
     6061 aaagggaaaa aaattatgaa gaattgagtt tacttttctt aggtaacagt ttaaaataac
     6121 tttaaattaa aagctcccta aagggaataa attacagaga agacaaatca ggaggaaacc
     6181 ttgcaggatg ctggaacagt tactttgaaa atctatctaa aatttaattc atgcatgtct
     6241 ttacttaatc ctggtgtttc tatccttagg aaatagagct taacattaat atatgcatat
     6301 atttttttac atgtaggatt ctagtttcta tcttctgagc tcaagaaagc taaactcaac
     6361 aaacagggta aaaatcttca actctcgcct caaattcaat ggtcctttgt cctgacaaaa
     6421 gttagacttg tctaataagc tggtattttt agggcatgat accctcccat taagtactta
     6481 aactaccacg gcagagatag gaaacctaag ctttgcccca tggtgaagta aagaacaaaa
     6541 gcccccttgc cccagatctc tagcatgact tgtaaagtct tcctcggctc acagcttcac
     6601 tgttactggt cacctcctaa ctgctctgtc cacctgtact gtcacacacc tggagaggca
     6661 gggcagccct gcaagtaaag gacgcccaga gtggagcccc tgggcaggca gcactcactc
     6721 ctgtggctct agtgattgtc catctgtatg tggaaagtca ggaagctgaa gtgcccaaga
     6781 gaaatcatga atcgctgatg acactgtaac agaaatgccc tttgaagcag ctataactca
     6841 tgcaatgagt tttaaaaaca gagactggtt ttaatctttg aaaacaatgt ctggttcgtc
     6901 agaatgtttg ttgctgttct tccccaccca ttatttgtat gacataacca ctgtgacagg
     6961 gtgcagtgtc tcttcgcccc cccaggattt tcctagtagt ttctgttagg acagctgcca
     7021 cggcagatcc tcctaagaca gcagcagagc ggtggacgtg tgcctgcaga gcggtggaaa
     7081 gggtgatcgg tgggcagctc atctaatgcc agcacatttg actcttgtcc ttgactcggg
     7141 ctgaataacg aggttgaaat atggatttgg gagagcaaca ggctatggaa tgatgacgaa
     7201 gactgtcatt tcaaacaaag caaaagaaac aggttttcta cccccacctt gctatgacac
     7261 atggagctgt gtgctagctg aaatgggctg tcagaagtga ctgtggggac tgagcacctc
     7321 tactaacatt tcttgtctgt cctagcatcc tttctacttc taacgagtca ttcttttgct
     7381 ttaaatgaag tgaagaatga tgagtaacag agggacgaca tagcagtagg aaaaagacct
     7441 aaagtgcacc aaccccttgc agggctcagc tgatttctgt gaaataaact attttaaatg
     7501 ttaattatgc taagagcacc tctaaaaatt atgtcttaaa tttcaagttt cacttttgga
     7561 aactactcct gaaaagacat tgaatatagg tgggaaagta taaaatgttt ctgacacaat
     7621 gactcagtat tattcagtgt ttaatctcaa attcgttata acacaagtgt catcagtggg
     7681 ttaaaacgtt ggatgttttt gttaatatac ttaaaactgt aaccagtgaa taacaccgta
     7741 gtatttttta ttatagatta tattttattt caataaactt tgatatttag actgaaaa
//
