LOCUS       NM_001377067            5648 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus membrane integral NOTCH2 associated receptor 1
            (Minar1), mRNA.
ACCESSION   NM_001377067 XM_001055454 XM_001066296
VERSION     NM_001377067.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5648)
  AUTHORS   Zhang,H., Zhang,Q., Gao,G., Wang,X., Wang,T., Kong,Z., Wang,G.,
            Zhang,C., Wang,Y. and Peng,G.
  TITLE     UBTOR/KIAA1024 regulates neurite outgrowth and neoplasia through
            mTOR signaling
  JOURNAL   PLoS Genet 14 (8), e1007583 (2018)
   PUBMED   30080879
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5648)
  AUTHORS   Ho,R.X., Meyer,R.D., Chandler,K.B., Ersoy,E., Park,M.,
            Bondzie,P.A., Rahimi,N., Xu,H., Costello,C.E. and Rahimi,N.
  TITLE     MINAR1 is a Notch2-binding protein that inhibits angiogenesis and
            breast cancer growth
  JOURNAL   J Mol Cell Biol 10 (3), 195-204 (2018)
   PUBMED   29329397
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JAXUCZ010000008.1.
            
            On or before Dec 12, 2019 this sequence version replaced
            XM_001055454.5, XM_001066296.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.1846956.1,
                                           SRR26360194.1165056.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMN12840105
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-874               JAXUCZ010000008.1  99048116-99048989   c
            875-3227            JAXUCZ010000008.1  99029510-99031862   c
            3228-3482           JAXUCZ010000008.1  99024174-99024428   c
            3483-5648           JAXUCZ010000008.1  99017228-99019393   c
FEATURES             Location/Qualifiers
     source          1..5648
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q31"
     gene            1..5648
                     /gene="Minar1"
                     /note="membrane integral NOTCH2 associated receptor 1"
                     /db_xref="GeneID:501033"
                     /db_xref="RGD:1591930"
     exon            1..874
                     /gene="Minar1"
                     /inference="alignment:Splign:2.1.0"
     exon            875..3227
                     /gene="Minar1"
                     /inference="alignment:Splign:2.1.0"
     CDS             927..3680
                     /gene="Minar1"
                     /note="ubiquitination and mTOR signaling protein"
                     /codon_start=1
                     /product="major intrinsically disordered Notch2-binding
                     receptor 1"
                     /protein_id="NP_001363996.1"
                     /db_xref="GeneID:501033"
                     /db_xref="RGD:1591930"
                     /translation="MEANQEASLFLVKILEELDSKQNTVSYQDLCKSLCAQFDLSQLA
                     KLRSVLFYTACLDPNFPATLFKDKMKCSVNNQQSKKIMVAADIVTIFNLIQMNGGTAK
                     EKLPTSCHKVRKEEASFESCRSDAEVCSPTVCEPLNCELSERPFSRGYPTRQSSKCRK
                     MDCKECPQFVPASEPNFLLGVSKEVKNRAASLDRLQALSPYSVASPQPCEMQRTYFPM
                     NIENESISDQDSLPIGQGIKETFISSEEPFMVQSCVQKRNIFKEDFHNLMTVSPSLVG
                     TTNKAEEDHGEPRSQKELHKPPFFNHSFEMPYHSQYLNPVYSPIPDKRRAKHESLDDL
                     QASTYFGPTPVMGTQDTRRCPGRPSKQTPWPAKSWSLNTEEVPDFERSFFNRNPSEEK
                     LRYPNSGNQTPNFSGPDRHPVYLVPKDQQKVLPAGYAVKPNGLKSKEIPSPVDLEKHE
                     AVKKFKDKSISCTSGQHSSDTSSVGTQTEQHVLDPPKCKDLCSAGQAKYSDRHAMKHS
                     DDDSEIVSDDISDIFRFLDDMSISGSTGVIQSSCYNSTGSLSQLHKSDCDSSPEHNLA
                     KITNGVSGSKGDKCNRPENVHHSEEELKSSVCKLVLRIGEIERKLESLAGVREEISQV
                     LGKLNKLDQKIQQPEKVNVQIDLNSLTSEAPSDDSASPRVFHAHSGSHGPKLENSPDW
                     CCSDVSGSNSESLRVKALKKSLFTRPSSRSLTEENSATESKIASISNSPRDWRTITYT
                     NRMSLNEEEIKDAGPANNKDWHRKSKEADRQYDIPPQHRLPKQPKDGFLVEQVFSPHP
                     YPSSLKAHMKSNPLYTDMRLTELAEVKRGQPSWNIEEYARNTGDKGKLTALDLQTQES
                     LNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALITAAACTVILVIVVPICT
                     MKS"
     exon            3228..3482
                     /gene="Minar1"
                     /inference="alignment:Splign:2.1.0"
     exon            3483..5648
                     /gene="Minar1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggccaaga gggaaaacat caatgagcca agtgaccagt ttgccctggc ctcctgaagc
       61 actgcagagt ctgaggcccc ggaagggcga gcatagtgcg ctgggagaaa aggagagcga
      121 ctgacaatgt tagcttctgc ttctccactg ggggccgcag tcaccttcac catcgggaaa
      181 tagggagaag caaaccccgg gggtggatct ggccctaggc tcgctccagc tccaacctct
      241 gcttgctttt gccccagcgc agcaggcgct actcaaaacg agacagaggc cttcttagga
      301 ctctgggggt gcgggcaccc actctctagg tggctgcagc ctctggcagg gcacgccctc
      361 ggcgctattg ccgcgcccct ctccagtccg cccctcccgc cccagggagc gcgtacccag
      421 tgctggagag tcctcccttc ctcagctccc caggcgggag atgatggaga ggctagactg
      481 gatctctgac catagggttc ctggcccgaa ctgcccacgg tatcaaagtc cgtgacgtgg
      541 cgacactggc tgagcctcag aaaccgatca gggctgcatc ctgaggccgc agaaagcccc
      601 aacattatgc aagtgggcac tggctgccga ctgcccagga aaacccgggt gagaccctag
      661 cttgcagatc cggatcttgc gctgcggggg ctgaagttgc cctatgccag ggacgttgcc
      721 ccaagtgcaa agcctgggct gccctgcagc ctaggactct tttgcctagg gaaccttcag
      781 gaagctctgc gttggaggcg gagtggacca ccacctcaga gcctctcaaa acctgcggag
      841 gaccggggac caagagctgg agcagccccc agaggataga actgactgat gttccagtgt
      901 agtcagtgag cttgcgaatc taaaccatgg aggccaatca ggaagcttct ctctttttgg
      961 tgaagatctt agaagaattg gacagtaaac aaaatactgt ttcttatcaa gacctgtgca
     1021 agtcactatg tgctcagttt gatctgtctc agcttgcaaa actgagaagt gtgcttttct
     1081 acacagcatg cctcgatccc aactttccag ccactttatt caaagacaag atgaaatgct
     1141 ctgtaaataa tcagcagtca aagaaaatca tggtggcggc agatattgtg acaatcttca
     1201 acctgatcca gatgaatggg ggcactgcca aggagaagct gcccacaagt tgccacaagg
     1261 tgcgcaagga ggaggcttcc tttgagtctt gccggtcgga cgccgaggtg tgcagcccca
     1321 cagtttgtga gcctctcaac tgcgagctga gtgagaggcc cttcagccga ggctatccca
     1381 ccaggcagtc atcgaaatgc cggaagatgg actgtaagga atgcccacag ttcgtccctg
     1441 cctctgagcc caacttcctt ttgggtgtta gcaaagaggt gaaaaatcgg gcagcctctc
     1501 tggacaggct gcaagccctc tctccgtatt ctgtagccag ccctcagcct tgtgaaatgc
     1561 agaggacata tttccctatg aatattgaga atgagtccat ttcagatcag gactctctgc
     1621 ctatcggcca aggcatcaaa gagaccttca tctcaagtga ggaaccattc atggttcagt
     1681 cctgtgttca gaaaaggaac atcttcaaag aagacttcca caatctgatg actgtgtctc
     1741 ccagtttggt tggtacaact aacaaagcag aggaggatca tggggagccc cggagtcaga
     1801 aggagctcca caagccaccc ttcttcaacc atagctttga gatgccttac cacagccagt
     1861 acctgaaccc agtgtattcc cccatccctg acaaaaggcg agcaaagcat gaaagcttag
     1921 atgaccttca agcctctacc tattttggac ccactccagt gatgggaaca caagatacca
     1981 ggcgctgtcc agggaggccc agtaaacaga cgccatggcc cgccaaaagc tggagcctaa
     2041 acacagagga agtgcctgat tttgaacgct cctttttcaa tagaaatccc tctgaagaga
     2101 agctacgcta tccaaattct ggcaaccaga cacccaactt ctcaggccca gacaggcatc
     2161 cagtttatct ggtgccaaag gatcaacaga aggttctccc tgctggctac gcagtgaaac
     2221 cgaatggact caaatctaaa gagattccat cccctgttga cctggagaag cacgaagcag
     2281 tcaagaagtt taaagacaaa agcatcagct gcaccagtgg gcagcacagc tcagatacca
     2341 gcagtgtggg tacccagaca gagcagcatg tcctggaccc cccaaaatgc aaagacttgt
     2401 gttctgcggg gcaggccaag tacagcgaca ggcatgccat gaagcactcg gatgatgact
     2461 cagaaattgt cagcgacgac atcagtgaca ttttccggtt tcttgatgac atgagcatca
     2521 gcggctccac gggagtgata cagtcatcct gctacaacag taccggctcc ttgtctcagc
     2581 ttcataagtc agactgtgat agttcaccag agcataacct tgccaaaatc accaatgggg
     2641 tctccgggag caagggagac aaatgtaacc ggcctgaaaa cgtccaccat tccgaggaag
     2701 agctgaagag cagcgtgtgc aaactggttc tcaggattgg tgagatcgag cgaaagctgg
     2761 aatcactagc aggggtccga gaggaaattt cccaggtcct tggaaaactc aataaactgg
     2821 atcagaaaat acagcagcca gagaaagtga atgtgcagat tgacctgaac tccttgacca
     2881 gcgaggcacc ttctgatgac agcgcctctc cgagggtctt ccatgcacac agtggctccc
     2941 atggaccaaa gctggagaat agtcctgact ggtgctgctc cgatgtcagt ggaagtaaca
     3001 gtgaaagcct gcgagtcaag gccttaaaga aaagcctctt taccaggcca tcttccaggt
     3061 ccctgactga ggagaacagt gccacagagt ccaaaattgc cagcatctcg aactctccca
     3121 gagactggcg aaccatcaca tataccaacc ggatgagcct caatgaggag gagataaaag
     3181 atgccggccc agccaataac aaagactggc atcggaaatc aaaggaggca gacaggcagt
     3241 atgacatccc cccacagcac cgactgccca agcaacccaa agatggcttc ctggtggaac
     3301 aggtgttcag ccctcatccc tacccctcct ccctcaaggc ccacatgaag agcaaccccc
     3361 tgtatacaga catgcgtctg accgagctag ctgaggtgaa gcggggccag ccttcttgga
     3421 acattgagga atatgctcgg aacactggtg acaaaggcaa gctgacagcc ctggacctgc
     3481 agacccaaga atctttaaac ccaaacaact tagagtactg gatggaagat atttatactc
     3541 caggctatga ttcattacta aaacggaaag aagctgaatt cagacgagcc aaggtttgca
     3601 agattgctgc tcttatcact gccgctgctt gcacagtcat tcttgtcatt gttgtaccta
     3661 tctgcacaat gaagtcctga acctgtggac tcagcgttac atgcagctca tgactcccaa
     3721 cgactttctc tctaatttca aaagctgatt ccactgtggc tacagtctgc tggaatagag
     3781 acaaaatcct ggatgctttt ctacagtgcc gaaggtcatc atcggagagt acgtactccg
     3841 gaacgacatc tgccttgctg ttaagcgcag gcatagctac cctccgatat attttcaaaa
     3901 gtacaatatc cttttccaca taaggaatgc catggattat cagtaaataa aaattggact
     3961 cttccattca gatgatgatt cttggtgggc attaagttat acagaacaga tccaaatagc
     4021 tgctctttga aggagctgac tgacttggac acaacaattg aataataata ataaaaaaag
     4081 caaaggtttc cttaacactc taagtttgtt gttggcgatg tgactggatg tgtgtccaca
     4141 agaatgtggc ttctctctgg acttttatca agggctattg acttccttct tgcccttctg
     4201 ccattgtctg tagaacatct gaattgctgc agctcttgat agcagctttc tgaattttct
     4261 tctttggccc aggtatgaag gagctgtact tccaagccaa gcatgatata cagcatccta
     4321 cttttgtaga atgggccaag atactcagga taggcaacct tcctgttgtt cccaaaatga
     4381 tgtggggaag cttgctggtt aggggacgtt caacatccga aggtcacagc caccctaaag
     4441 gatctttggt tctagctctg gcatgtggct ctgttccctg atttttctaa atcttggtgg
     4501 tacctgatgc tctattctga agagtttgga acttgtcctt gtgccttgaa gagcagagac
     4561 aatggtgaca ctttgacatt ctaattataa accatgattt ccatccacca atggcaccga
     4621 ccacttatgt ggctttaaac aagattttga atgcttattc aataatgtgg taaaggtacc
     4681 aagttctcct cagctacaat aacatttact ccagagtttt aaatatttgt ctgcagtgca
     4741 agaaaaaaaa gtatctattt aatcatttat ctacctatgt ctaaatacct gagtttcatt
     4801 tttgtcttca ctaagtaaat atcgagagca agattttttc caagtgtaca agaagctgtt
     4861 gtaattttat tagcgtttga tctctgttcc cacctgattg gtgctttgac aataattggg
     4921 cagaaagact ccttatcaac atctgtgtct aatgtcttac tataggttaa ataaaaaaaa
     4981 tggtcatcag aaaccttaaa tctatttaat aacaaactgg attgtacaca catttggtag
     5041 gaatcacttt gggaagtatg tactcttcct gcaagtggaa tctgaggagc cttttaattt
     5101 ctaaagcaat aggggtccag catccatcct aaatatttcc aaataatgct gagcttgctg
     5161 caccagattc tgttgtcact agtgaagagt ggtcagtgca ttttataatg ctaacaggtg
     5221 agggatagag tctctcacct gtagggggcc ttcgtcctta gaggtcttca tggcatctat
     5281 ttctattgat atgctatgtt tactaatggt cttcagttag acgactgaaa cttaagcctt
     5341 agaatggagg acttattgaa aatgattgaa tatgaatgca tacttacaca cacatacatg
     5401 catgcatgca aacatacata catacataca cacatacata catacatata tgtctgttgt
     5461 cagaagttta gtctcttggt gctctgtttt agattgggca cttcaaataa ggttgtttca
     5521 cttcaaaatg gatattaggt tacatccttt ggagtccctg ttccattcca gcccacctgc
     5581 aagcaatgac ttctgtgcca cactgtgatg taaccattct gccccacacc acagattaag
     5641 ctatcaaa
//
