LOCUS       NM_001017450            1640 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Rattus norvegicus migration and invasion inhibitory protein (Miip),
            mRNA.
ACCESSION   NM_001017450 XM_216589
VERSION     NM_001017450.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1640)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Mar 11, 2021 this sequence version replaced NM_001017450.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FJ618907.1, BC079047.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-167               JAXUCZ010000005.1  163582546-163582712 c
            168-364             JAXUCZ010000005.1  163580851-163581047 c
            365-727             JAXUCZ010000005.1  163580230-163580592 c
            728-812             JAXUCZ010000005.1  163579781-163579865 c
            813-921             JAXUCZ010000005.1  163577933-163578041 c
            922-974             JAXUCZ010000005.1  163577799-163577851 c
            975-1104            JAXUCZ010000005.1  163577346-163577475 c
            1105-1201           JAXUCZ010000005.1  163577134-163577230 c
            1202-1339           JAXUCZ010000005.1  163576260-163576397 c
            1340-1640           JAXUCZ010000005.1  163575689-163575989 c
FEATURES             Location/Qualifiers
     source          1..1640
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..1640
                     /gene="Miip"
                     /gene_synonym="Iip45"
                     /note="migration and invasion inhibitory protein"
                     /db_xref="GeneID:298643"
                     /db_xref="RGD:1587376"
     exon            1..167
                     /gene="Miip"
                     /gene_synonym="Iip45"
                     /inference="alignment:Splign:2.1.0"
     exon            168..364
                     /gene="Miip"
                     /gene_synonym="Iip45"
                     /inference="alignment:Splign:2.1.0"
     CDS             251..1411
                     /gene="Miip"
                     /gene_synonym="Iip45"
                     /note="invasion-inhibitory protein 45; IGFBP-2-Binding
                     Protein, IIp45; migration and invasion-inhibitory
                     protein-like"
                     /codon_start=1
                     /product="migration and invasion-inhibitory protein"
                     /protein_id="NP_001017450.1"
                     /db_xref="GeneID:298643"
                     /db_xref="RGD:1587376"
                     /translation="MAETKDTVQLRLLSLELLKQLWAGHEAMCQSVTRAASESNLDYS
                     SSSNNLEMPLSQETSASSVAPNSQDKRHVWDPLDSHRGDTYDVAWYGKVNSRVDSLPP
                     ATCQHQEPQEGLRPSSVPLLATEGLKRPVSLGGPKGLGPDKAQVPRSLPLRLGKLSKP
                     KVTFSQESSVPESSWYSRPCLDYDWTAGSLDSSSPVSSESEAYFSMLQRFREDNREDC
                     VCNSPEAVFPELQESSGVEEDHECVYCYRINRRLFPEPLDPGAPCCLCGIPRDEQGPQ
                     TLVEPVQVRVSIPLSIMDPPHQYRIHRRKSFDASDTFALPRHCLLGWDILPPKSEKTS
                     VPKSLDLWSSVSHGAAQRRNLSATNPSYQALRSRVPPPFWSEPQVARLCPSH"
     exon            365..727
                     /gene="Miip"
                     /gene_synonym="Iip45"
                     /inference="alignment:Splign:2.1.0"
     exon            728..812
                     /gene="Miip"
                     /gene_synonym="Iip45"
                     /inference="alignment:Splign:2.1.0"
     exon            813..921
                     /gene="Miip"
                     /gene_synonym="Iip45"
                     /inference="alignment:Splign:2.1.0"
     exon            922..974
                     /gene="Miip"
                     /gene_synonym="Iip45"
                     /inference="alignment:Splign:2.1.0"
     exon            975..1104
                     /gene="Miip"
                     /gene_synonym="Iip45"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1201
                     /gene="Miip"
                     /gene_synonym="Iip45"
                     /inference="alignment:Splign:2.1.0"
     exon            1202..1339
                     /gene="Miip"
                     /gene_synonym="Iip45"
                     /inference="alignment:Splign:2.1.0"
     exon            1340..1640
                     /gene="Miip"
                     /gene_synonym="Iip45"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgaaaccgc cgcttccgga tgcgaagaaa caagtcctgg taccgccaat tggccgactg
       61 ggacagcggc ggaggccccg cctcggcact agccaattag gacaaccact ggaggttccg
      121 cccctgctag gtgcggatcc ctggctgctg gaaacctggg cttccgggtg gaacccaggc
      181 tgagtacctc ctgtgagtgc accgcagccc agagatggtg acattgctgt gagaagccta
      241 catgaccaac atggcggaga ctaaagatac tgtccagctt cgactgctca gcctggagct
      301 cctgaagcag ctttgggctg ggcacgaggc catgtgtcag tcagtgacca gagcagcatc
      361 agagtcaaac ctggactata gcagcagcag caacaactta gagatgccac tgtcccaaga
      421 gacttctgct tcctcagtgg cccccaactc acaggacaaa agacacgtgt gggacccatt
      481 ggacagtcat cgaggtgaca cttatgatgt ggcctggtat ggcaaagtca actccagggt
      541 ggactctctc ccacctgcca catgccaaca ccaggagccc caggaaggac tacggccctc
      601 ctcagtaccc ttgctagcca ctgaaggtct gaagcggcca gtgtctttgg gaggcccaaa
      661 aggtctgggg cctgacaagg cacaggtccc aaggtccctc ccgttacgac taggcaagct
      721 gtctaagccc aaagtgacct tctcccagga gtcttcagtg cctgagagca gctggtactc
      781 taggccatgc ctagactatg attggaccgc agggtccctg gacagtagct ctcccgtcag
      841 tagtgaatcc gaagcctact tctctatgct gcagaggttt cgagaggaca acagagagga
      901 ttgtgtttgc aattcccctg aagctgtatt cccagagctg caagagagca gtggtgtgga
      961 agaggaccat gagtgtgtgt actgttaccg catcaaccgc cgcctgtttc ctgagcctct
     1021 ggatccgggt gccccttgct gtctgtgtgg gataccccgg gatgagcagg gccctcaaac
     1081 tctggtagag ccagtacaag tcagggtgag catccccctg tccatcatgg accctccaca
     1141 ccagtaccga attcacagaa ggaagagctt tgatgcatct gacacttttg ctctgcctcg
     1201 gcactgtctg ctgggctggg acatcctgcc tccaaagtca gagaaaacct ctgtccccaa
     1261 gagcctggac ctctggtcct ctgtgtccca tggagcagca cagcgccgga atctgtcagc
     1321 cacaaaccca tcctatcagg ccttgcgatc acgggtccca ccacctttct ggtcagagcc
     1381 tcaggttgcc cggctctgtc cctcccacta gaagccatga ggactgacta tacagaaggc
     1441 aacagtattc taccagtgcc atcagcttcc cctgaggaga agcaccggag agctggaagt
     1501 ggacaagatg gcggtggctg agctgtctct cctcggttgt ccccttcgtc tcctgagagc
     1561 tagaaagtgg aaaatccagg gcagagggga gggagtgctc tgagtagtgt actaataaag
     1621 ctcagggccg tacacttcca
//
