LOCUS       NM_001131012            4586 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus MIER1 transcriptional regulator (Mier1), mRNA.
ACCESSION   NM_001131012 XM_001058293 XM_233245
VERSION     NM_001131012.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4586)
  AUTHORS   Derwish,R., Paterno,G.D. and Gillespie,L.L.
  TITLE     Differential HDAC1 and 2 Recruitment by Members of the MIER Family
  JOURNAL   PLoS One 12 (1), e0169338 (2017)
   PUBMED   28046085
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4586)
  AUTHORS   Matsuda,A., Suzuki,Y., Honda,G., Muramatsu,S., Matsuzaki,O.,
            Nagano,Y., Doi,T., Shimotohno,K., Harada,T., Nishida,E., Hayashi,H.
            and Sugano,S.
  TITLE     Large-scale identification and characterization of human genes that
            activate NF-kappaB and MAPK signaling pathways
  JOURNAL   Oncogene 22 (21), 3307-3318 (2003)
   PUBMED   12761501
REFERENCE   3  (bases 1 to 4586)
  AUTHORS   Ding,Z., Gillespie,L.L. and Paterno,G.D.
  TITLE     Human MI-ER1 alpha and beta function as transcriptional repressors
            by recruitment of histone deacetylase 1 to their conserved ELM2
            domain
  JOURNAL   Mol Cell Biol 23 (1), 250-258 (2003)
   PUBMED   12482978
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC168252.1.
            
            On or before Aug 15, 2008 this sequence version replaced
            XM_233245.4, XM_001058293.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168252.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132264
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..4586
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q33"
     gene            1..4586
                     /gene="Mier1"
                     /gene_synonym="RGD1562337"
                     /note="MIER1 transcriptional regulator"
                     /db_xref="GeneID:313418"
                     /db_xref="RGD:1562337"
     exon            1..115
                     /gene="Mier1"
                     /gene_synonym="RGD1562337"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..1645
                     /gene="Mier1"
                     /gene_synonym="RGD1562337"
                     /note="mesoderm induction early response 1 homolog;
                     mesoderm induction early response 1, transcriptional
                     regulator"
                     /codon_start=1
                     /product="mesoderm induction early response protein 1"
                     /protein_id="NP_001124484.1"
                     /db_xref="GeneID:313418"
                     /db_xref="RGD:1562337"
                     /translation="MAEPSVESSSPGGSAASEDHEFDPSADMLVHDFDDERTLEEEEM
                     MEGETNFSSEIEDLAREGDMPIDELLSLYGYGSTVQLPEEEEEEEEEEEEGEDDEDAD
                     NDDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVTSQDAQEIIRPRRCKYFDTNS
                     EIEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGVCRYKENEKVYENDDQLLWDPEY
                     LPEDKVIVFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCSFDTEEALRRLRF
                     NVKAAREELSVWTEEECRNFEQGLKAYGKDFHLIQANKVRTRSVGECVAFYYMWKKSE
                     RYDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSTSQSEK
                     EDGMLSNSNQNGVSSNGPGEILNKEEVKVEGLHVNGPTGGNKKPLLTDVDTNGYEENN
                     LATDPKLAHMTARNENDFDEKNERPAKRRRINSSGKESPGSSEFFQEAVSHGKFEEHE
                     NTND"
     exon            116..140
                     /gene="Mier1"
                     /gene_synonym="RGD1562337"
                     /inference="alignment:Splign:2.1.0"
     exon            141..286
                     /gene="Mier1"
                     /gene_synonym="RGD1562337"
                     /inference="alignment:Splign:2.1.0"
     exon            287..448
                     /gene="Mier1"
                     /gene_synonym="RGD1562337"
                     /inference="alignment:Splign:2.1.0"
     exon            449..581
                     /gene="Mier1"
                     /gene_synonym="RGD1562337"
                     /inference="alignment:Splign:2.1.0"
     exon            582..646
                     /gene="Mier1"
                     /gene_synonym="RGD1562337"
                     /inference="alignment:Splign:2.1.0"
     exon            647..719
                     /gene="Mier1"
                     /gene_synonym="RGD1562337"
                     /inference="alignment:Splign:2.1.0"
     exon            720..871
                     /gene="Mier1"
                     /gene_synonym="RGD1562337"
                     /inference="alignment:Splign:2.1.0"
     exon            872..953
                     /gene="Mier1"
                     /gene_synonym="RGD1562337"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1048
                     /gene="Mier1"
                     /gene_synonym="RGD1562337"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1176
                     /gene="Mier1"
                     /gene_synonym="RGD1562337"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1316
                     /gene="Mier1"
                     /gene_synonym="RGD1562337"
                     /inference="alignment:Splign:2.1.0"
     exon            1317..4565
                     /gene="Mier1"
                     /gene_synonym="RGD1562337"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgccgaagcg gcggcggaga cagcagcggg agccccgcgg cccaggcgca catccgggtt
       61 ctggccacga cccgccgcgg cgatgtgacc cggtggcgcg gccaacatgg cggagccatc
      121 tgttgagtct tcaagtccag ggggctcagc agcgtcagag gaccatgagt ttgatccgtc
      181 agctgacatg ctggttcatg attttgatga tgagcgaaca ttagaagaag aagaaatgat
      241 ggaaggagag acaaacttca gttctgaaat agaggatctt gcgagggaag gcgacatgcc
      301 aatcgacgag cttctcagcc tctatggtta tggcagcact gttcagttac ctgaagagga
      361 ggaggaggag gaagaagagg aggaagaagg tgaagatgat gaagatgcgg acaatgatga
      421 caacagtggc tgcagtgggg aaaataaaga agagaatata aaggattcat cgggtcagga
      481 ggatgaaact cagtcttcca atgatgatcc ctcacagtct gttacttccc aagatgctca
      541 ggaaataatc cgcccacgtc gatgtaaata ttttgataca aatagtgaaa tagaagaaga
      601 atctgaagaa gatgaagatt atattccctc agaagactgg aaaaaggaaa tcatggtagg
      661 ctccatgttt caagctgaga ttccagttgg cgtttgtaga tacaaagaaa atgaaaaagt
      721 gtatgaaaat gatgatcagc ttctgtggga tccagaatat ttaccagaag ataaagtgat
      781 tgtctttctt aaggatgcat ctagaagaac aggggatgag aaaggtgtag aagcaattcc
      841 tgaaggatct catataaaag acaatgaaca ggctttatat gaattggtta aatgcagttt
      901 tgatacagaa gaagccttga gaagactgag atttaatgtc aaagcagctc gagaggaatt
      961 atctgtgtgg acagaggaag aatgtagaaa ttttgaacaa gggctgaagg cctatgggaa
     1021 agattttcat ctgattcagg ctaataaagt ccgaacaaga tcagttggtg aatgtgtagc
     1081 attctattac atgtggaaaa agtctgagcg ttatgatttc tttgctcagc aaacaaggtt
     1141 tggaaaaaag aaatataatc ttcatcctgg tgtaacggat tacatggatc gtcttttgga
     1201 tgaaagtgaa agtgctgctt ctagccgagc accatcccct cctcccaccg cctcaaacag
     1261 tagtaccagc cagtcggaga aagaagacgg catgctcagc aatagcaatc agaatggtgt
     1321 gtcatctaat ggaccaggag aaatactaaa caaagaagaa gtaaaagttg aaggcttaca
     1381 tgttaatgga ccaacaggtg gaaataagaa accacttctt acagatgtgg acactaatgg
     1441 ttacgaagaa aataaccttg ccactgaccc aaaacttgcc catatgactg caagaaatga
     1501 aaatgatttt gatgaaaaaa atgagagacc tgccaaaagg cggcggataa acagcagtgg
     1561 gaaagaaagt ccgggttcgt ctgagttttt ccaggaagca gtctcacatg ggaagtttga
     1621 ggaacatgaa aacacaaatg actaactctt aggcctattt tactttcttt gcagtaaagt
     1681 ctggtttgac tacaattttc agggttgggg gggtgacctt tagaaagctg atttccttga
     1741 agcagttgtt aactcttgaa attggaatta ggtcctaact ttaagaaatg ggattcataa
     1801 ttctactttt tgcaagttct tttacttcaa attttgaagc cctctttaag gatataaaaa
     1861 cattggtaaa tttgaatgac ccaaagactt aactgcacct tctcctttga gaaacaagtc
     1921 atatttgact aaaaggtaat ctttccttat tctttatgag gaagaaaaaa gtttgtttct
     1981 gttcaacacc aatttttttt attatctaga aatgtcttta caacagacat ttttctctcc
     2041 atacaaattg aacatcgtca ttaaggaaac cctcatgaat cctgaaggtt atgctagcat
     2101 gatttttata tgtagaagtt taaaaataaa ccaagtcagg tttgtatttg taaaattgtt
     2161 gacatcaatg atgtctttcc atattcttat ctgggcttaa gaaatacatt ctgtattttt
     2221 ccagattctt tgtagccttt gaaagatttt tacagtacat atgtcttgac tgagctgtcc
     2281 tttcttaata caaaaaaagc ttgtataatt ttcttaactt gtacagttgg taaactttta
     2341 tgagaggaac tgatattctg agtctgtcag ctttcatttt attttgctaa gatttttcta
     2401 atgaattttt aagtgtgtgt gtagttaacc aagtcatgtt tcttatccag gtggtaaaag
     2461 cattcataaa gaattatgtt attttcaaac ttctacttac tgacataatt tgggacttct
     2521 aaatttcagc atgatactca gattacaagc ttgtttgcat ttgctataat tttataaatt
     2581 aattgtgaaa caaaacaaag acttactgtc agcttaagtg tgtagatgta tcgtgctgaa
     2641 tagaatcctg ttcagttact ctcatgtgcc ctacaagatt tctcattgtt tcagtcaaca
     2701 gaaagggaag gtcacgtgat gttgcaatat tgccacatcc aaggagtaac tgttgacagg
     2761 tagcaatatt catttttatg agaaaatagt ggttttaaga attttcagat ctttccagtt
     2821 gtaatccagt ttgtcacatt tgatactttt tccaaaatga aacacataca aaataaccat
     2881 tgttctgtgt gactttaaaa agggttattg cactagcctt gtaagaatgg atgccatttt
     2941 attgttagtg caaaattctt cttacaaaat gtagttttat acagctgata gaccaatcta
     3001 tctctggact gttttttagt gaatgatgat taactacctt ttctcacaca ggcacatccc
     3061 caaatgctgc cttcagtttg atctcagccg tcagttcaag agccactgct ttcaaagaca
     3121 gatctgtgtc cttttagtgg ctcagttgtc tgatgcaggg tgggttaagg tttgcactga
     3181 gaatgatcgc ccaggcctct ccctcatagt attcttacat ttgtccagac tgcttccctt
     3241 cacaatgggt acaaactttt ctttccccaa atcagtatta gaagccacct tgacagcaca
     3301 tcataataat acgcatttac tgttttctgc agaaatagtc cagtgagttg ccttcaggtg
     3361 gaagtgctga gaagcacgag agggtttagt ttgttttatt gaaaacatta atttatccag
     3421 aatggcagta ggtcaagtac ctttagcaga tggtcatagc ttgtctccct gcccaccccc
     3481 acagagtctc actgtgtagc ccaggctggc ctggaactta acaacccttc tacctcagcc
     3541 cgctaatgct gagattggag gtgtttccca ccacacccag caacagtcta ttttctaaag
     3601 caggttttat tatatgagtc caggccatcc cagctccttg tcacaggtga tctttaagtg
     3661 atgctatgct ttttaatcat tacactatgg aagatgtcag tccgcctttt aaaggatgcc
     3721 tctgctcgac acgttcttgg acttctcgaa actgttgtaa caggaacgtt ttaaggaaat
     3781 tctcaggcat gttggcaaat gtgccaggtg tataagtgtt cataaatctt ttctttttaa
     3841 agtatgcata atgaaacatt cctctaatac acaaggctca gcttttccca actatattct
     3901 gtgtttgtat aggtatttca ccctttgttc aaaaaatgca gccactgaaa cttaagtcat
     3961 tgcactttta aacagtttga caatatcatg agtaatctgc ttaagatttg gtgtatttcc
     4021 taactgttga acacttaagt aactgagatg agaaaataag cattcatgag tagggatgta
     4081 gctcagttgc tggaatgctt acccaacatg catgcaaaat gggttccatc cccagtacca
     4141 caggaactgg gtatagtggt gcatgcctgt catcctaagc acttgggagg tggaggcagg
     4201 agaatcagaa gttcaaggcc atcctcatta cctggtgagt tgaggccagc ctgatatgct
     4261 gactcagata gaaatggctc tgttggtagt tattaggtcc tagccaagca ctgtcatttt
     4321 catctggaac atacaatgat gatgtattta tgatgtattc tcactaaggt tcacaatctg
     4381 taactcagtt caacacagat ctcttgagct ttaaaaggta tttgaagtaa tttaagtagg
     4441 cattcaaaat tatgaattag atgtttttaa atttctgcat aataattttg cactgtaaaa
     4501 tatgtccttt ctcccatttc cttctgccat tctgatatgc tcattaaaat atttttgtaa
     4561 gcataaaaaa aaaaaaaaaa aaaaaa
//
