LOCUS       NM_001191594             600 bp    mRNA    linear   ROD 22-SEP-2024
DEFINITION  Rattus norvegicus microsomal glutathione S-transferase 3 (Mgst3),
            mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001191594 XM_213943
VERSION     NM_001191594.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 600)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 600)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 600)
  AUTHORS   Yang,S.L., Chen,L.J., Kong,Y., Xu,D. and Lou,Y.J.
  TITLE     Sodium nitroprusside regulates mRNA expressions of LTC4 synthesis
            enzymes in hepatic ischemia/reperfusion injury rats via NF-kappaB
            signaling pathway
  JOURNAL   Pharmacology 80 (1), 11-20 (2007)
   PUBMED   17496435
REFERENCE   4  (bases 1 to 600)
  AUTHORS   Schroder,O., Sjostrom,M., Qiu,H., Stein,J., Jakobsson,P.J. and
            Haeggstrom,J.Z.
  TITLE     Molecular and catalytic properties of three rat leukotriene C(4)
            synthase homologs
  JOURNAL   Biochem Biophys Res Commun 312 (2), 271-276 (2003)
   PUBMED   14637132
REFERENCE   5  (bases 1 to 600)
  AUTHORS   Townsend,D.M. and Tew,K.D.
  TITLE     The role of glutathione-S-transferase in anti-cancer drug
            resistance
  JOURNAL   Oncogene 22 (47), 7369-7375 (2003)
   PUBMED   14576844
  REMARK    Review article
REFERENCE   6  (bases 1 to 600)
  AUTHORS   Jakobsson,P.J., Mancini,J.A., Riendeau,D. and Ford-Hutchinson,A.W.
  TITLE     Identification and characterization of a novel microsomal enzyme
            with glutathione-dependent transferase and peroxidase activities
  JOURNAL   J Biol Chem 272 (36), 22934-22939 (1997)
   PUBMED   9278457
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            [WARNING] On Oct 18, 2024 this sequence was replaced by
            NM_001191594.2.
            
            On Jul 17, 2010 this sequence version replaced XM_213943.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB580770.1, SRR22399492.592632.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760400 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-22                JAXUCZ010000013.1  82080274-82080295   c
            23-146              JAXUCZ010000013.1  82065362-82065485   c
            147-220             JAXUCZ010000013.1  82064326-82064399   c
            221-278             JAXUCZ010000013.1  82062563-82062620   c
            279-351             JAXUCZ010000013.1  82061001-82061073   c
            352-600             JAXUCZ010000013.1  82059480-82059728   c
FEATURES             Location/Qualifiers
     source          1..600
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q24"
     gene            1..600
                     /gene="Mgst3"
                     /note="microsomal glutathione S-transferase 3"
                     /db_xref="GeneID:289197"
                     /db_xref="RGD:1306373"
     exon            1..22
                     /gene="Mgst3"
                     /inference="alignment:Splign:2.1.0"
     exon            23..146
                     /gene="Mgst3"
                     /inference="alignment:Splign:2.1.0"
     CDS             30..488
                     /gene="Mgst3"
                     /EC_number="2.5.1.18"
                     /codon_start=1
                     /product="glutathione S-transferase 3, mitochondrial"
                     /protein_id="NP_001178523.1"
                     /db_xref="GeneID:289197"
                     /db_xref="RGD:1306373"
                     /translation="MAVLSKEYGFVLLTGAASFVMVLHLAINVGKARKKYKVEYPVMY
                     STDPENGHMFNCIQRAHQNTLEVYPPFLFFLTVGGVYHPRIASGLGVAWIIGRVLYAY
                     GYYTGDPSKRYRGAVSSLALFALMGTTVCSAFQHLGWIKPGLGSGSRSCH"
     exon            147..220
                     /gene="Mgst3"
                     /inference="alignment:Splign:2.1.0"
     exon            221..278
                     /gene="Mgst3"
                     /inference="alignment:Splign:2.1.0"
     exon            279..351
                     /gene="Mgst3"
                     /inference="alignment:Splign:2.1.0"
     exon            352..600
                     /gene="Mgst3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtctgcacc aggcgcgtca agagccaaga tggctgtcct ctctaaggaa tatggattcg
       61 tgcttctcac tggtgccgcc agctttgtga tggtgctcca cctagccatc aacgtgggca
      121 aagcccgcaa gaagtacaag gtagagtacc ctgtcatgta cagcacagat cctgagaatg
      181 ggcatatgtt caactgcatt cagcgcgccc accagaacac attggaggtg taccctccct
      241 tcctattctt cctaaccgtg ggaggtgttt accacccgcg catagcttct ggcctgggcg
      301 tggcgtggat tattgggcga gttctttacg catatggcta ctacacggga gaccctagca
      361 agcggtatcg aggagctgtg agctctcttg ccctctttgc cctgatgggc acaactgtgt
      421 gctctgcttt ccagcatctc ggctggatta aacccggcct aggcagtggg tccagatcct
      481 gccactgagg aacgggaggc ctttcacctc tcagtcgcct tcaacgaccc gcccttactt
      541 ccagctccac tgttttttaa atataataaa aacttatctg gcgtcagcct cgtacctaaa
//
