LOCUS       NM_001127533            2395 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus alpha-1,3-mannosyl-glycoprotein
            4-beta-N-acetylglucosaminyltransferase B (Mgat4b), mRNA.
ACCESSION   NM_001127533 XM_001070870 XM_220372
VERSION     NM_001127533.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2395)
  AUTHORS   Kurimoto A, Kitazume S, Kizuka Y, Nakajima K, Oka R, Fujinawa R,
            Korekane H, Yamaguchi Y, Wada Y and Taniguchi N.
  TITLE     The absence of core fucose up-regulates GnT-III and Wnt target
            genes: a possible mechanism for an adaptive response in terms of
            glycan function
  JOURNAL   J Biol Chem 289 (17), 11704-11714 (2014)
   PUBMED   24619415
REFERENCE   2  (bases 1 to 2395)
  AUTHORS   Takamatsu S, Antonopoulos A, Ohtsubo K, Ditto D, Chiba Y, Le DT,
            Morris HR, Haslam SM, Dell A, Marth JD and Taniguchi N.
  TITLE     Physiological and glycomic characterization of
            N-acetylglucosaminyltransferase-IVa and -IVb double deficient mice
  JOURNAL   Glycobiology 20 (4), 485-497 (2010)
   PUBMED   20015870
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before May 23, 2008 this sequence version replaced
            XM_220372.4, XM_001070870.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166514.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2395
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q22"
     gene            1..2395
                     /gene="Mgat4b"
                     /gene_synonym="RGD1562836"
                     /note="alpha-1,3-mannosyl-glycoprotein
                     4-beta-N-acetylglucosaminyltransferase B"
                     /db_xref="GeneID:303100"
                     /db_xref="RGD:1562836"
     exon            1..358
                     /gene="Mgat4b"
                     /gene_synonym="RGD1562836"
                     /inference="alignment:Splign:2.1.0"
     CDS             262..1908
                     /gene="Mgat4b"
                     /gene_synonym="RGD1562836"
                     /EC_number="2.4.1.145"
                     /note="mannoside acetylglucosaminyltransferase 4,
                     isoenzyme B; mannosyl (alpha-1,3-)-glycoprotein
                     beta-1,4-N-acetylglucosaminyltransferase, isozyme B"
                     /codon_start=1
                     /product="alpha-1,3-mannosyl-glycoprotein
                     4-beta-N-acetylglucosaminyltransferase B precursor"
                     /protein_id="NP_001121005.1"
                     /db_xref="GeneID:303100"
                     /db_xref="RGD:1562836"
                     /translation="MRLRNGTFLTLLLFCLCAFLSLSWYAALSGQKGDVVDIYQREFL
                     ALRDRLHAAEQESLKRSKELNLVLEEIKRAVSERQALRDGEGNRTWGRLTEDPRLKPW
                     NVSHRHVLHLPTVFHHLPHLLAKESSLQPAVRVGQGRTGVSVVMGIPSVRREVHSYLT
                     DTLHSLISELSPQEKEDSVIVVLIAETDTQYTSAVTENIKALFPTEIHSGLLEVISPS
                     PHFYPDFSRLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLEDDIVAKPNY
                     LSTMKNFALQQPSEDWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYRDKPIDWLLDH
                     ILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFGKHAL
                     RKEHVNPPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPAAGDFIRFRFFQPLRLERFF
                     FRSGNIEHPEDKLFNTSVEVLPFDNPQSEKEALQEGRSATLRYPRSPDGYLQIGSFYK
                     GVAEGEVDPAFGPLEALRLSIQTDSPVWVILSEIFLKKAD"
     exon            359..544
                     /gene="Mgat4b"
                     /gene_synonym="RGD1562836"
                     /inference="alignment:Splign:2.1.0"
     exon            545..685
                     /gene="Mgat4b"
                     /gene_synonym="RGD1562836"
                     /inference="alignment:Splign:2.1.0"
     exon            686..819
                     /gene="Mgat4b"
                     /gene_synonym="RGD1562836"
                     /inference="alignment:Splign:2.1.0"
     exon            820..866
                     /gene="Mgat4b"
                     /gene_synonym="RGD1562836"
                     /inference="alignment:Splign:2.1.0"
     exon            867..980
                     /gene="Mgat4b"
                     /gene_synonym="RGD1562836"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1056
                     /gene="Mgat4b"
                     /gene_synonym="RGD1562836"
                     /inference="alignment:Splign:2.1.0"
     exon            1057..1171
                     /gene="Mgat4b"
                     /gene_synonym="RGD1562836"
                     /inference="alignment:Splign:2.1.0"
     exon            1172..1302
                     /gene="Mgat4b"
                     /gene_synonym="RGD1562836"
                     /inference="alignment:Splign:2.1.0"
     exon            1303..1410
                     /gene="Mgat4b"
                     /gene_synonym="RGD1562836"
                     /inference="alignment:Splign:2.1.0"
     exon            1411..1604
                     /gene="Mgat4b"
                     /gene_synonym="RGD1562836"
                     /inference="alignment:Splign:2.1.0"
     exon            1605..1683
                     /gene="Mgat4b"
                     /gene_synonym="RGD1562836"
                     /inference="alignment:Splign:2.1.0"
     exon            1684..1771
                     /gene="Mgat4b"
                     /gene_synonym="RGD1562836"
                     /inference="alignment:Splign:2.1.0"
     exon            1772..1884
                     /gene="Mgat4b"
                     /gene_synonym="RGD1562836"
                     /inference="alignment:Splign:2.1.0"
     exon            1885..2395
                     /gene="Mgat4b"
                     /gene_synonym="RGD1562836"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctcttgccg ccttgcccca accctgctct gcccgggccc agcctcagat cgaggccgcc
       61 agcgccgtgc accgcggagg agcagcccgc acgcatcccc cacctccacc ccggttcccg
      121 ccctgcccgt agcggtctct cccgggcccg cagttcctcc ggggccgggg cccccgccgc
      181 ctccgggccc ccgtgcccgg gccccggtcc cccgggccat gcggcctcgg ccccgccggc
      241 gcccgccgcg cactggggga gatgaggctc cgcaatggca ccttcctgac gctgctgctc
      301 ttctgcttgt gcgccttcct ctctctctcc tggtacgcag cgctcagcgg ccagaaaggt
      361 gacgtggtgg acatttacca gcgcgagttc ctggcactga gagaccgttt gcacgcggct
      421 gagcaagaga gcctgaagcg ctccaaggag ctaaacctgg tgctggaaga aatcaagagg
      481 gcagtgtccg agaggcaggc gctgcgggac ggagaaggca atcgcacttg gggccgccta
      541 acagaggatc cgcgactgaa gccgtggaac gtctcgcaca ggcacgtact tcatctgccc
      601 accgtcttcc accatctgcc gcacctgctg gctaaggaaa gcagtctgca gcccgcagtg
      661 cgagtgggcc agggccgcac cggagtgtcc gtggtgatgg gcattccgag cgtgcggcgc
      721 gaggtgcact cgtacttgac tgacacattg cactcgctca tctcggagct gagcccgcag
      781 gagaaggaag actcggtcat cgtggtgctg atcgccgaga ctgatacaca gtacacgtcg
      841 gcagtgacag agaacatcaa agccttgttc cccacagaga tccattctgg gctcctggaa
      901 gtcatctccc cttcccctca cttctatcct gacttctccc gccttcgaga gtcctttggg
      961 gatcccaagg agagagtcag gtggaggacc aaacagaacc tcgattactg cttcctcatg
     1021 atgtatgcac agtccaaagg catctactac gtgcagctgg aggatgacat tgtagccaag
     1081 cccaactact tgagcactat gaagaacttt gccctccagc agccctctga ggactggatg
     1141 atcctggagt tctcgcagct gggcttcatt gggaagatgt tcaagtcact ggatctgagc
     1201 ctgattgtgg aattcatcct tatgttctac cgagacaagc ccatcgactg gctcctggac
     1261 cacatcctgt gggtgaaagt ctgcaaccct gagaaggatg cgaaacattg tgatcggcag
     1321 aaggccaacc ttcggatccg cttcaagccg tccctcttcc agcacgtggg cactcactca
     1381 tccctggcgg gcaaaatcca gaaactgaag gataaagact ttggaaagca tgctctacgg
     1441 aaggagcacg tgaacccacc ggcggaggtg agcacaagcc tgaagacgta ccagcatttc
     1501 accctggaga aggcctactt gcgagaggat ttcttctggg ccttcacacc tgctgccgga
     1561 gacttcatcc ggttccgctt cttccagcca ctgcgcctcg agcggttctt tttccgaagc
     1621 gggaacattg agcacccaga agataagctc ttcaacactt ctgtggaggt gctgcccttc
     1681 gataaccccc agtcagagaa ggaggccctt caggagggcc gctcagccac tctccggtac
     1741 cctcggagcc ctgatggcta cctccagatt ggctccttct acaagggtgt agctgaagga
     1801 gaagtggatc ctgcctttgg ccccctggaa gcactgcgtc tctccattca gactgactcc
     1861 ccggtgtggg tcattttgag tgagatcttt ctgaaaaagg ccgactaagt agaaggcttc
     1921 caagggtgct ctgtggccgg ctctggagcc cacggttctg agggtgtcgc tgctactgct
     1981 gctgctgccc cagaggacca ggcatatcca ccccacctgg agggttctgc ctggcaggcg
     2041 gctcgggctg gcctggggtt caccgctggc ccggaggccc cagaagctgg tgctgctcct
     2101 gcccgccggg ccgcgggaga ggcaggcggc ccccacactg tgcctgaggg ccggcctgct
     2161 gccgcccaaa aagaactgaa ccgaaccgtt tgccccggcc agtggtcatg agccaggcca
     2221 ttagaagagc tttttcttgg gtgcccgctg tgtgcggcgc ggaacactgg aatgcataca
     2281 ctactttatg tgctgtgttt tttattcttg gatacatttg attttttcac gtaagttcgc
     2341 atatacttct ataagagcgt gacttgtaat aaagggttaa tgaagtatct ctctc
//
