LOCUS       XM_039108641           14477 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus maltase-glucoamylase (Mgam),
            transcript variant X1, mRNA.
ACCESSION   XM_039108641
VERSION     XM_039108641.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Jan 25, 2024 this sequence was replaced by
            NM_001427451.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14477
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..14477
                     /gene="Mgam"
                     /note="maltase-glucoamylase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 23
                     ESTs, 29 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 2 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:103690059"
                     /db_xref="RGD:9369725"
     CDS             97..13632
                     /gene="Mgam"
                     /codon_start=1
                     /product="maltase-glucoamylase isoform X1"
                     /protein_id="XP_038964569.1"
                     /db_xref="GeneID:103690059"
                     /db_xref="RGD:9369725"
                     /translation="MARRRFKKFSTLELVLIVLLLILFIVAVVLIVLLANSTEPNAVD
                     AETTGTPDTTLTRTTLNFPECPVLSEAERINCIPDQSSNKDTCDQRGCCWDPQGSISV
                     PCYFSRNHGYKMESDLANTTAGFTAALKNLASAPVFGNGIENILLTAEYQTSNRFHFK
                     LTDQTKERYEVPHEHVKPFSGNAASSLNYNVEVFKEPFSIKVTRKSNNRVLFDSSIGP
                     LLFSDQFLQLSTHLPSANVYGLGEHVHQQYRHDMNWKTWPMFARDTTPNEDGNNLYGV
                     QTFFLCLEDNSGLSFGVFLMNSNAMEVTLQPTPAITYRITGGILDFYVFLGNTPEQVV
                     QEYLELIGRPTLPSYWTLGFQLSRYDYGSLDKMKIVVERNRAAQLPYDVQHADIDYMD
                     QRKDFTYDPVNFKGFPEFVKELHNNGQKLVIILDPAISNNSLSSNPYGPYDRGSAMKV
                     WVNSSDGNALIGKVWPGTTVFPDYTSPNCAVWWKKEIELFHNEVEFDGIWIDMNEVSN
                     FVDGSVSGCSQNNLNYPPFTPKVLDGNLFSKTLCMDAVQHWGKQYDVHNLYGYSMAIA
                     TEEAVKTVFPDKRSFILTRSTFAGSGKFAAHWLGDNTATWKDLQWSIPGMLEFNLFGI
                     PMVGADICGFAMNTYEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGEDSLLLNSS
                     RHYLNIRYTLLPYLYTLFYRAHSRGDTVARPLLHEFYEDSNTWDIDRQFLWGPGLLIT
                     PVLDQGAEKVKAYVPDATWYDYETGEQLAWRKQSVEMELPEDKIGLHLRGGYIFPTQQ
                     PATTTEASRKNPLGLIIALDKNKEAKGELFWDDGQTKDTVAKNLYLFTEFSATQNRLD
                     VTISSPNYKDPNNLEFQEIKIFGTQEFRNVKVKQNGVLLQMSPQVNYNSNLKVATITN
                     IHLMLGEAYTVEWDIFTRDEEKIDCYPDEHGVSEANCIARGCIWEVSNTPGVPHCYFA
                     NELYSVSNIQYNSHGATADIFLKASTYSNAFPSTPVNQLQLKVAYHKDQMLQFKIYDP
                     NRSRYEVPVPLNIPSAPSSTPEGRLYDVFIKENPFGIQIRRKSTGTVIWDSQLLGFTF
                     NDMFIRISTRLPSTYIYGFGETEHTTFKIDMNWQTWGMFSRDEPPGYKKNSYGVHPYY
                     MGLEEDGNAHGVLLMNSNAMDVTFQPMPALTYRTVGGILDFYVFLGPTPEIVTEQYTE
                     LIGRPVMVPYWSLGFQLCRYGYENDTEIANLYDEMVAKRIPYDVQYSDIDYMERQLDF
                     KLNPKFSGFPDLINRMKDNGMRVILILDPAISGNETEPYPAFTRGVENDVFISYPNNG
                     GIVWGKVWPDYPNITVDPSLDWDSQVQQYRAYVAFPDFFRDSTALWWKNEIKELHSNS
                     QDPAKSLKFDGLWIDMNEPSSFVNGAVPSGCTDTTLNRPPYMPHLEARDRGLSSKTLC
                     MESEHILPDGSRVRHYDVHSLYGWSQTRPTYEAMQEVTGERGIVITRSTFPSSGRWGG
                     HWLGDNTAAWDQLGKSIIGMMDFSLFGISYTGSDICGFFQDAEYEMCVRWMQLGAFYP
                     FSRNHNTIGTKRQDPVSWNETFEDISRSVLETRYTLLPYLYTLMYKAHKEGSTVVRPL
                     LHEFLADRETWNVDKQFLLGPAFLVSPVLELNARNVTAYFPKAQWYDYYTGADINSTG
                     EWRTLPAPLEHINLHVRGGYILPWQQPALNTNLSRKKPLGLLIALNENKEARGELFWD
                     DGQSKDTVAKNIYLFSEFSVTQNRLDVTISSPNYKDPNNLEFQEIKIFGTQEIRNVKV
                     KQNGVLLQMSPQVNYNSNLKVATITNIHLVLGEAYTVEWDIYSKDVERIDCYPDEHGV
                     SEANCTARGCIWEVSNTPGVPHCYFANELYSVSNIQYDSHGATADISLKASPYSNAFP
                     STPVNQLQLKVTYHKDQMLQFKIYDPNRSRYEVPVPLNIPSAPSSTPEGRLYDVFIKE
                     NPFGIQIRRNSTGTVIWDSQLLGFTFNDMFIRISTRLPSTYIYGFGETEHTTFKIDMN
                     WQTWGMFSRDEPPGYKKNSYGVHPYYMGLEEDGNAHGVLLMNSNAMDVTFQPMPALTY
                     RTTGGILDFYVFLGPTPEIVTQQYTELIGRPVMVPYWSLGFQLCRYGYENDTEIANLY
                     DEMVAKQIPYDVQYSDIDYMERQLDFKLSPKFSGFPDLINRMKDNGMRVILILDPAIS
                     GNETEPYPAFTRGVENDVFISYPNNGGIVWGKVWPDYPNITVDPSLDWDSQVQQYRAY
                     VAFPDFFRNSTALWWKNEIKELHSNSQDPAKSLKFDGLWIDMNEPSSFVNGAVPSGCT
                     DTTLNRPPYMPHLEARDRGLSSKTLCMESEHILPDGSRVRHYDVHSLYGWSQTRPTYE
                     AVQEVTGERGIVITRSTFPSSGRWGGHWLGDNTAAWDQLGKSIIGMMDFSLFGISYTG
                     SDICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTKRQDPVSWNKTFEDISRSVLET
                     RYTLLPYLYTLMYKAHKEGSTVVRPLLHEFLADRETWNVDKQFLLGPAFLVSPVLEPN
                     ARNVTAYFPKAQWYDYYTGADINSTGEWRTLPAPLEHINLHVRGGYILPWQQPALNTN
                     LSRKKPLGLLIALNENKEARGELFWDDGQSKDTVAKNIYLFSEFSVTQNRLDVTISSP
                     NYKDPNNLEFQEIKIFGTQEILNVKVKQNGVLLQMSPQVNYNSNQKVATITNIHLVLG
                     EAYTVEWDIYSKDMERIDCYPDEHGVSEANCTARGCIWEVSNIPGVPHCYFANELYSV
                     SNVQYDSHGATADISLKASPYSNAFPSTPVNQLQLKVTYHKDQMLQFKIYDPNHSRYE
                     VPVPLNIPRTPSSTVDGRLYDVLIKENPFGIQIRRKSTGTVIWDSQLLGFTFNDMFIR
                     ISTRLPSTYIYGFGETEHTTFKIDMNWHTWGMFSRDEPPGYKKNSYGVHPYYMGLEED
                     GNAHGILLLNSNAMDVTFQPMPALTYRTTGGILDFYVFLGPTPEIVTQQYTELIGRPV
                     MVPYWSLGFQLCRYGYENDAEIANLYDEMVAKQIPYDVQYSDIDYMERQLDFKLNPKF
                     SGFPDLINRMKDNGMRVILILDPAISGNETEPYPAFTRGVENDVFIRYPNNGDIVWGK
                     VWPDYPNIVVNSSLDWDSQVEQYRAYVAFPDFFRNSTALWWKKEIEELYRNTQEPAKS
                     LKFDGLWIDMNEPSSFVNGAVPSGCSDTTLNRPPYMPYLEARDRGLSSKTLCMESEHI
                     LPDGSRVRHYDVHSLYGWSQTRPTYEAVQEVTGERGIVITRSSFPSSGRWGGHWLGDN
                     TAAWDQLGKSIIGMMDFSLFGISYTGSDICGFFQDAEYEMCVRWMQLGAFYPFSRNHN
                     TIGTRRQDPVSWNKTFEDISRSVLETRYTLLPYLYTLMYKAHTEGSTVVRPLLHEFVS
                     DRETWSIDKQFLLGPAFLVSPVLEPDARNIRSYFPRALWYDYYTGENINSTGEWRTLS
                     APLEHINLHVRGGYILPWQRPALNTHLSRKNPLGLIIALDENKEARGELFWDDGQSKD
                     LTTNNILCKFSVTQNRLDVSTSKSTYTDPDNLTFQEIKIFGTQALYNVTVKHNGMVNQ
                     MSPQVSYDPNMKVALITGIQLLLNESYTVEWDGSIRDGEKMDCYPDQHGASEANCTAR
                     GCVWEVSNSPGVPFCYFVNELYSVSNVQYDSHGASANISLKASPYSNAFPSTPVNELQ
                     LKVTYHKDEMLQFKIYDPNHSRYEVPVPLNIPSSPSSTPDNRSYDVFIKENPFGIEIR
                     RKGTGSVIWDSRLLGFTFNDMFIRISTRLPSTYIYGFGETEHTTFKIDMNWHTWGMFS
                     RDEPPGYKKNSYGVHPYYMGLEEDGNAHGILLMNSNAMDVTLQPMPALTYRTTGGVLD
                     FFVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYENDTEIANLYDDMVAKKI
                     PYDVQYSDIDYMERQLDFKLNPKFSGFPDLINRMKHDGMRVILILDPAISGNETEPYP
                     AFTKGVENDVFIRYPNNGDIVWGKVWPDYPNITVDPSLDWDSQVEQYRAYVAFPDFFR
                     NSTALWWKDEIKELHSNTQDPAKSLKFDGLWIDMNEPSSFVNGAVPSGCSDATLNRPP
                     YMPHLEARDRGLSSKTLCMESEHILPDGSRVRHYDVHSLYGWSQTRPTYEAVQEVTGE
                     RGIVITRSTFPSSGRWGGHWLGDNTAAWDQLGKSIIGMMDFSLFGISYTGSDICGFFQ
                     DAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWNKTFEDISRSVLETRYTLLPYL
                     YTLMYKAHTEGSTVVRPLLHEFVSDRETWNIDKQFLLGPAFLVSPVLEPNARTVAAYF
                     PKARWYDYYTGVDINARGEWKTLQAPLEYINLHVRGGYILPWQEPAMNTQLSRKKSMG
                     LKAALNDEGLAEGWLFWDDGKSINITNQYYLARFSVSQNTLQTHEMFNNYITGTVPLY
                     LGYIEIWGLSSPSITSVRISGKNLNEEVLADYNTTTQILRVNVTDKNISLHAFQSLTW
                     S"
ORIGIN      
        1 tttctgggca gagaagactg cttctcactt taattccttt tctccttgtc taggtggtgt
       61 gtgatgtgac tggctcggct cccatgtgga acaaagatgg caagacgaag gtttaagaag
      121 ttcagcaccc tggagcttgt gctcattgtt ctgctgctta tactgttcat cgtcgcggtg
      181 gttctaattg tgctcttagc caactccacg gaaccaaatg ctgtggacgc tgaaacaact
      241 ggcactccag acactacact caccaggacc actcttaact ttcccgaatg cccagtgcta
      301 agtgaggcgg aacggataaa ttgcatccct gaccagtcat ctaataagga tacatgtgac
      361 cagcgtggct gctgctggga tcctcaggga tccatcagtg ttccttgcta cttttccaga
      421 aatcatggct acaaaatgga gagtgacctt gcaaacacaa ctgcaggatt cacagctgca
      481 ctgaaaaact tagcttctgc acctgtgttt ggaaatggca tcgaaaacat cctgcttaca
      541 gcagagtacc agacatcaaa tcgcttccat tttaagttga ctgaccaaac caaggagagg
      601 tatgaggtgc cccacgagca tgtgaaaccc ttcagtggaa atgctgcttc ttccttgaac
      661 tacaatgttg aggtcttcaa ggagccattt agcatcaaag tcaccagaaa aagcaataac
      721 cgtgtgctgt ttgactcaag tattgggccc ctcctcttct ctgaccagtt cctgcagctc
      781 tccacccacc tgccaagtgc taatgtgtat ggtctgggtg agcatgtgca ccagcagtac
      841 cggcatgata tgaattggaa gacctggcct atgtttgcca gagatacaac cccgaatgag
      901 gacggaaata acttgtatgg tgtgcaaaca ttcttcctgt gccttgaaga taatagtgga
      961 ttgtcctttg gggtgttcct gatgaacagc aatgccatgg aggttaccct tcagcctacc
     1021 ccagcaatca cataccgcat cactggggga attctggact tctatgtgtt tttggggaac
     1081 acacctgagc aagttgttca agaataccta gagctcattg ggcggccaac tctgccttca
     1141 tactggacac ttgggtttca gctcagccgg tatgattatg gaagcctaga taaaatgaaa
     1201 atagttgtgg agagaaaccg tgcagcacaa ctcccttatg atgttcagca tgctgacatt
     1261 gattatatgg atcagagaaa ggacttcact tatgacccag tgaactttaa aggcttccca
     1321 gagtttgtca aggagctaca caataatgga cagaagcttg ttatcatttt ggatccagcc
     1381 atttccaaca actctctctc aagtaatccc tatggcccat atgatagggg ttcagcaatg
     1441 aaagtctggg tgaatagttc tgatggcaat gcactcattg gaaaggtctg gcctggaaca
     1501 actgtgtttc ctgattacac cagtcccaac tgtgctgttt ggtggaaaaa agaaattgag
     1561 cttttccaca atgaagtgga gtttgatgga atttggattg atatgaatga agtctccaac
     1621 tttgttgatg gttcagtttc tggatgttcc caaaacaact tgaattatcc cccattcacc
     1681 ccaaaggtcc tggatgggaa cttgttctct aagactctct gcatggatgc agttcagcac
     1741 tggggaaagc agtatgatgt ccacaatctg tacggctatt ccatggccat tgccactgaa
     1801 gaagccgtga agaccgtgtt cccagacaag agaagcttca ttctaacacg ttctaccttt
     1861 gccggttctg gcaaatttgc agcccactgg ttaggagata acactgccac ctggaaggac
     1921 cttcagtggt ccatcccagg catgcttgag ttcaaccttt tcggtatccc aatggtaggg
     1981 gccgatatat gtggctttgc catgaacaca tatgaggagt tgtgcaggcg ctggatgcag
     2041 ctgggggcat tttatccatt ttcccggaat cacaatgggc aaggttacaa ggaccaggat
     2101 cctgcttctt tcggagaaga ctccttgctg ttgaattcat ctaggcacta ccttaacatc
     2161 cgctacacgt tgctgcctta cctctacact cttttctaca gagcacacag ccggggagac
     2221 actgtagcta ggcctcttct gcatgagttc tatgaagaca gcaatacttg ggacatagac
     2281 agacaatttc tgtggggacc aggtctcctc atcactcctg ttctggatca gggtgcagag
     2341 aaagtgaaag cgtatgtgcc ggatgccacc tggtatgact atgagaccgg agagcaattg
     2401 gcatggagaa agcaaagcgt tgagatggaa cttcctgaag acaagattgg acttcacctt
     2461 cgagggggct acatcttccc cacacagcag ccagccacaa ccacagaagc cagtcggaag
     2521 aatcctcttg gtcttatcat tgccctggat aagaacaagg aagcaaaagg agagctgttc
     2581 tgggatgatg ggcagacaaa ggacactgtg gccaaaaacc tttacctttt caccgaattc
     2641 tccgccactc aaaaccgttt ggatgtgaca atttcaagtc caaactacaa ggatcccaat
     2701 aacctggaat tccaggaaat taaaatcttt gggacacagg aatttcgcaa tgttaaagtg
     2761 aaacagaatg gggttctcct tcaaatgtct cctcaagtca attacaattc aaacctgaag
     2821 gttgctacca tcacaaatat ccatctcatg ctgggagaag catatacagt cgagtgggac
     2881 atcttcacga gggatgagga aaagatagat tgttatccag atgaacatgg tgtttctgag
     2941 gcaaactgca ttgcccgtgg ctgcatctgg gaggtttcca acactcctgg cgtccctcat
     3001 tgctactttg ctaatgaact gtactcagtc agcaatattc agtacaactc ccatggggcc
     3061 acagctgaca ttttcttgaa ggcttctact tatagcaatg ccttcccctc tacacccgtg
     3121 aatcaactgc aactgaaggt ggcctaccac aaggaccaaa tgctgcagtt taagatctat
     3181 gatcccaacc gcagtcgtta tgaagttcca gtccctctga acatccccag tgctccgtcg
     3241 agcacccctg aaggccgtct gtatgatgtc ttcatcaagg agaatccatt tgggattcaa
     3301 attcgccgaa agagcacagg cactgtaatc tgggactctc agctccttgg cttcaccttc
     3361 aatgacatgt tcatccgcat ctccacccgc ctgccctcca catacatcta tggctttggg
     3421 gaaactgagc acacaacctt caagatagac atgaactggc aaacatgggg catgttttcc
     3481 agggatgagc ccccagggta caaaaagaat tcctatggtg tccaccctta ctacatgggg
     3541 ctggaggagg atggcaatgc ccatggagtc ctcttgatga acagcaatgc catggatgta
     3601 accttccagc ccatgcctgc cctgacatac cgaaccgtag ggggcattct ggacttttat
     3661 gtgttcttgg gcccaactcc agagattgtt actgaacaat acacagagtt gattggtcgg
     3721 cctgtgatgg taccttattg gtccctggga ttccagctgt gtcgctatgg atatgagaat
     3781 gatacggaga ttgccaacct atatgatgaa atggtggcta agcggatccc atatgatgtg
     3841 cagtactcag acattgacta catggagagg cagctggact tcaagctcaa ccctaagttc
     3901 tctgggtttc cagacctgat caatcgcatg aaggacaatg ggatgcgggt catcctcatt
     3961 ctggatccag ctatttctgg caatgagaca gagccctatc ctgccttcac caggggagtg
     4021 gagaatgacg tcttcatcag ctatcccaat aatggaggca ttgtttgggg aaaggtctgg
     4081 cctgattacc ctaatatcac tgtggaccca tctctagact gggacagtca agtgcagcaa
     4141 taccgagctt atgtggcctt cccagacttt ttccgtgatt caactgccct ctggtggaag
     4201 aatgagatta aagaactcca cagcaactca caggatcctg caaagagctt gaagtttgat
     4261 ggcctgtgga ttgacatgaa tgaaccttcc agctttgtga atggggcagt tccttccggc
     4321 tgcactgaca ctactctgaa ccgtcctccc tacatgccac atttggaagc cagggacagg
     4381 ggcctgagca gcaagaccct gtgcatggag agcgagcaca tccttccaga tggctcccgg
     4441 gtgcggcact atgatgtaca cagcctgtat gggtggtccc agaccagacc cacctacgaa
     4501 gctatgcagg aggtgacagg agagagaggg attgtcatca cccgctccac attcccctct
     4561 tctggacgct ggggaggaca ctggctggga gacaacacag ctgcctggga ccagctgggg
     4621 aaatccatca ttggcatgat ggatttcagc ctctttggca tatcctatac tgggtcagac
     4681 atctgtgggt tctttcaaga tgccgaatat gagatgtgtg ttcgctggat gcagctgggc
     4741 gccttttacc ccttctccag gaaccacaac accatcggga ccaagaggca agaccctgta
     4801 tcctggaatg aaacctttga ggacatttcc agaagtgtgc tggagaccag atacaccctg
     4861 ttgccatatc tctacacctt gatgtacaaa gcccataagg agggcagcac agttgtgcgg
     4921 cctcttctgc atgagtttct ggcagaccgg gagacctgga acgtagacaa acagttcctg
     4981 ctgggtccag ccttcctagt cagccctgtc cttgaactta atgccagaaa tgtcactgca
     5041 tatttcccta aagcccagtg gtatgattat tacacgggtg cagatattaa ttcaacagga
     5101 gagtggagga ccttgccagc ccctcttgag cacattaatc ttcatgtccg agggggttac
     5161 atcttgccat ggcaacaacc tgccctgaac accaacttaa gtcggaagaa acctcttggt
     5221 ctcctcattg ctctgaacga gaataaagaa gcaagaggag agctgttctg ggatgatggg
     5281 cagtcaaagg acactgtggc caaaaacatt taccttttca gtgaattttc tgttacccaa
     5341 aaccgtttgg atgtaacaat ttcaagtcca aactacaagg atcccaataa cctggaattc
     5401 caggaaatta aaatctttgg gacacaggaa atccgcaatg ttaaagtgaa acagaatggg
     5461 gttctccttc aaatgtctcc tcaagtcaat tacaattcaa acctgaaggt tgctaccatc
     5521 acaaatatcc atcttgtgct gggagaagca tatacagttg agtgggacat ctactcaaag
     5581 gacgtggaaa ggatagattg ctatccagat gagcatggtg tttctgaggc aaactgcact
     5641 gctcgtggct gcatctggga ggtttccaac actcctgggg tccctcattg ctactttgct
     5701 aatgagctgt actcagtcag caatattcag tatgactccc atggggccac agctgacatt
     5761 tccttgaagg cttcacctta tagcaatgcc ttcccctcta cacccgtgaa tcaactgcaa
     5821 ctgaaagtga cctaccacaa ggaccaaatg ctgcagttta agatctatga tcccaaccgc
     5881 agtcgttatg aagttccagt ccctctgaac atccccagtg ctccatcgag cacccctgaa
     5941 ggccgtctgt atgatgtctt catcaaggag aatccatttg ggattcaaat tcgccgaaat
     6001 agcacaggca ctgtaatctg ggactctcag ctccttggct tcacctttaa tgacatgttc
     6061 atccgcatct ccacccgcct gccatccaca tacatctatg gctttgggga aactgagcac
     6121 acaaccttca agatagacat gaactggcaa acatggggca tgttttccag ggatgagccc
     6181 ccagggtaca agaagaattc ctatggtgtc cacccttact acatggggct ggaggaggat
     6241 ggcaatgccc atggagtcct cttgatgaac agcaatgcca tggatgtaac cttccagccc
     6301 atgcctgccc tgacataccg aaccacaggg ggcattctgg acttttatgt gttcttgggc
     6361 ccaactccag agattgttac tcaacaatac acagagttga ttggtcggcc tgtgatggta
     6421 ccttattggt ccctgggatt ccagctgtgt cgctatggat atgagaatga tactgagatt
     6481 gccaacctgt atgatgagat ggtggctaag cagatcccct atgatgtgca gtactcagac
     6541 attgactaca tggagaggca gctggacttc aagctcagcc ctaagttctc tgggtttcca
     6601 gacctgatca atcgcatgaa ggacaatggg atgcgggtca tcctcattct ggatccagct
     6661 atttctggca atgagacaga gccctatcct gccttcacca ggggagtgga gaatgacgtc
     6721 ttcatcagct atcccaataa tggaggcatt gtctggggaa aggtctggcc tgattaccct
     6781 aatatcactg tggacccgtc tctagactgg gacagtcaag tgcagcaata ccgagcttat
     6841 gtggccttcc cagacttttt ccgtaattca actgccctct ggtggaagaa tgagattaaa
     6901 gaactccaca gcaactcaca ggatcctgca aagagcttga agtttgatgg cctgtggatt
     6961 gacatgaatg aaccttccag ctttgtgaat ggggcagttc cttccggctg cactgacact
     7021 actctgaacc gtcctcccta catgccacat ttggaagcca gggacagggg cctgagcagc
     7081 aagaccctgt gcatggagag tgagcacatc cttccagatg gctcccgggt gcggcactat
     7141 gatgtacaca gcctgtatgg gtggtcccag accagaccca cctatgaagc agtgcaggag
     7201 gtgacaggag agagagggat cgtcatcacc cgctccacat tcccctcttc tggacgctgg
     7261 ggaggacact ggctgggaga caacacagct gcctgggacc agctggggaa atccatcatt
     7321 ggcatgatgg atttcagcct ctttggcata tcctatactg ggtcagacat ctgtgggttc
     7381 tttcaagatg ccgaatatga gatgtgtgtt cgctggatgc agctgggcgc cttttacccc
     7441 ttctccagga accacaacac catcgggacc aagagacaag accctgtatc ctggaataaa
     7501 acctttgagg acatttccag aagtgtgctg gagaccagat acaccctgtt gccatatctc
     7561 tacaccttga tgtacaaagc ccacaaggag ggcagcacag ttgtgcggcc tcttctgcat
     7621 gagtttctgg cagaccggga gacctggaac gtagacaaac agttcctgct gggtccagcc
     7681 ttcctagtca gtcctgtgtt ggaacctaat gccagaaatg tcactgcata tttccctaaa
     7741 gcccagtggt atgattatta cacgggtgca gatattaatt caacaggaga gtggaggacc
     7801 ttgccagccc ctcttgagca cattaatctt catgtccgag ggggttacat cttgccatgg
     7861 caacaacctg ccctgaacac caacttaagt cggaagaaac ctcttggtct cctcattgct
     7921 ctgaacgaga ataaagaagc aagaggagag ctgttctggg atgatgggca gtcaaaggac
     7981 actgtggcca aaaacattta ccttttcagt gaattttctg ttacccaaaa ccgtttggat
     8041 gtgacaattt caagtccaaa ctacaaggat cccaataact tggaattcca ggaaattaaa
     8101 atctttggga cacaggaaat ccttaatgtt aaagtgaaac agaatggggt tctccttcaa
     8161 atgtctcctc aagtcaatta taattcaaac cagaaggttg ctaccatcac aaatatccat
     8221 ctcgtgctgg gagaagcata tacagttgag tgggacatct actcaaagga catggaaagg
     8281 atagattgct atccagatga gcatggtgtt tctgaggcaa actgcactgc tcgtggctgc
     8341 atctgggagg tttccaacat ccctggggtc cctcattgct actttgctaa tgagctgtac
     8401 tcagttagca atgttcaata tgactcccat ggggccacag ccgacatctc cttgaaggct
     8461 tcaccttata gcaatgcctt cccctctaca cccgtgaatc aactgcaact gaaagtgacc
     8521 taccacaagg accaaatgct gcagtttaag atctatgatc ccaaccacag tcggtatgaa
     8581 gtcccagtcc ctttgaacat ccctaggact ccatccagta ctgttgacgg ccgtctgtat
     8641 gatgtcctca tcaaggagaa tccatttggg attcaaattc gccgaaagag tacaggcact
     8701 gtaatctggg actctcagct ccttggcttc accttcaatg acatgttcat ccgcatctcc
     8761 acccgcctgc cctccacata catctatgga tttggggaaa ctgagcacac aaccttcaag
     8821 atagacatga attggcatac atggggcatg ttttccaggg atgaacctcc agggtacaag
     8881 aagaattcct atggtgtcca cccttactac atggggctgg aggaggacgg caatgcccat
     8941 ggaatcctcc tgttgaacag caatgccatg gatgtaacct tccagcctat gcctgccctg
     9001 acataccgaa ccacaggggg cattctagac ttctatgtgt tcttgggccc aactccagag
     9061 attgttactc agcagtatac agagttgatt ggtcggcctg tgatggtacc ttactggtcc
     9121 ctgggattcc agctgtgtcg ctatggatat gagaatgatg ctgagatcgc caacttgtat
     9181 gatgagatgg tggctaagca gatcccctat gatgtgcagt actcagacat tgactacatg
     9241 gagaggcagc tggacttcaa gctcaaccct aagttctctg ggtttccaga cctgatcaat
     9301 cgcatgaagg acaatgggat gcgggtcatc ctcattctgg acccagccat ttctggcaat
     9361 gagacagagc cctatcctgc cttcaccagg ggagtggaga atgacgtctt catcagatat
     9421 cccaataatg gagacattgt ctggggaaag gtctggcctg attaccctaa tattgttgtg
     9481 aactcctctc tggactggga cagtcaagtg gagcaatatc gagcttatgt ggccttccca
     9541 gactttttcc ggaattcaac tgccctctgg tggaagaagg agattgaaga actctacagg
     9601 aacacacagg aaccggcaaa aagcttgaag tttgatggcc tgtggattga tatgaatgaa
     9661 ccttccagct ttgtgaatgg ggcagttcct tccggctgca gtgacactac tctgaaccgt
     9721 cctccctaca tgccatattt ggaagccagg gacaggggcc tgagcagcaa gaccctgtgc
     9781 atggagagcg agcacatcct tccagatggc tcccgggtgc ggcactatga tgtacacagc
     9841 ctgtatgggt ggtcccagac cagacccacc tacgaagcag tgcaggaggt gacaggagag
     9901 agagggattg tcatcacccg ctcctcattc ccctcttctg gacgctgggg aggacactgg
     9961 ctgggagaca acacagctgc ctgggaccag ctggggaaat ccatcattgg catgatggat
    10021 ttcagcctct ttggcatatc ctatactggg tcagacatct gtgggttctt tcaagatgcc
    10081 gaatatgaga tgtgtgttcg ctggatgcag ctgggcgcct tttacccctt ctccaggaac
    10141 cacaatacca tcggaaccag gagacaagac ccagtatcct ggaataaaac ctttgaggat
    10201 atttccagaa gtgtgctgga gaccagatac accctgttgc catatctcta caccttgatg
    10261 tacaaggccc acacagaggg cagcacagtc gtgcggcctc ttctccatga atttgtgtca
    10321 gaccgggaga cctggagtat agacaaacag ttcctgctgg gcccagcttt cctagtcagc
    10381 cctgtgctag aacctgatgc ccgaaacatc agatcatatt tccccagagc cctctggtat
    10441 gactactaca cgggtgaaaa tatcaattca acaggagagt ggaggacttt atcagcccct
    10501 cttgagcata tcaatcttca tgtccgtggg ggctacatcc tgccctggca acgacctgcc
    10561 ctgaacactc acttaagtcg gaagaatcct cttggtctta tcattgctct ggatgagaac
    10621 aaagaagcaa ggggagagct attctgggat gatgggcagt cgaaggatct cacaaccaat
    10681 aacattctgt gtaaattttc agtcactcaa aaccgcttgg atgtgagcac ttcaaaatca
    10741 acctacacgg atcctgataa cttaacattt caggagatta aaatttttgg aacacaggca
    10801 ctttacaatg ttacagtgaa acacaatggt atggtaaatc agatgtctcc tcaagtcagt
    10861 tatgatccaa acatgaaggt tgcacttatt acaggcatcc aacttctcct gaatgaatcc
    10921 tacacagtgg agtgggatgg cagcatcagg gatggagaaa agatggattg ttatccggat
    10981 caacatgggg cttctgaagc aaactgcact gcccgaggct gtgtctggga ggtttccaac
    11041 tctcctgggg tccccttttg ctactttgtc aatgagctgt actcagtcag caatgttcaa
    11101 tatgactccc atggggcttc agccaacatc tccttgaagg cttcacctta tagcaatgcc
    11161 ttcccctcta cacccgtgaa tgaactgcag ctgaaagtga cctatcacaa ggacgaaatg
    11221 cttcagttta agatctatga tccaaaccac agtcggtatg aagtcccagt ccctctgaac
    11281 atccccagct ctccatccag tacccctgac aaccgctcgt atgatgtgtt catcaaggag
    11341 aacccatttg ggattgaaat tcgtcggaag ggtacaggct ctgtcatctg ggactctcgg
    11401 ctccttggct tcaccttcaa tgacatgttc attcgcatct ccacccgcct gccctccaca
    11461 tacatctatg gctttgggga aactgagcac acaaccttca agatagacat gaactggcat
    11521 acatggggca tgttttccag ggatgagccc ccagggtaca agaagaattc ctatggtgtc
    11581 cacccttact acatggggct ggaggaggac ggcaatgccc atggaatcct cctgatgaac
    11641 agcaatgcca tggacgtgac attgcagccc atgcctgctc tgacgtaccg caccacaggg
    11701 ggagttctgg atttttttgt atttttgggg ccaactcctg agcttgtcac tcagcaatac
    11761 acagagttga ttggtcggcc tgtgatggta ccatactggt ccctgggatt ccagctgtgt
    11821 cgctatggat atgagaatga tactgagatc gccaacctgt atgatgacat ggtggctaag
    11881 aagatcccct atgatgtgca gtactcagac attgactaca tggagaggca gctggacttc
    11941 aagctcaacc ctaagttctc tgggtttcca gacctgatca atcgtatgaa gcatgatggg
    12001 atgcgggtca tcctcattct ggatccagct atttctggca atgagacaga gccctaccct
    12061 gccttcacca agggagtgga gaatgacgtc ttcatcagat atcccaataa tggagacatt
    12121 gtctggggaa aggtctggcc tgattaccct aatatcactg tggacccatc tctagactgg
    12181 gacagtcaag tggagcaata ccgagcttat gtggccttcc cagacttttt ccggaattca
    12241 actgccctct ggtggaagga tgagattaaa gaactccaca gcaacacaca ggatcctgca
    12301 aagagcttga agtttgatgg cctgtggatt gacatgaatg aaccttccag ctttgtgaat
    12361 ggggcagttc cctctggctg cagtgatgct actctgaacc gccctcccta catgccacat
    12421 ttggaagcca gggacagggg cctgagcagc aagaccctgt gcatggagag cgagcacatc
    12481 cttccagatg gctcccgggt gcggcactat gatgtacaca gcctgtatgg gtggtcccag
    12541 accagaccca cctacgaagc agtgcaggag gtgacaggag agagagggat cgtcatcacc
    12601 cgctccacat tcccctcttc tggacgctgg ggaggacact ggttgggaga caacacagct
    12661 gcctgggacc agctggggaa atccatcatt ggcatgatgg atttcagcct ctttggcata
    12721 tcctatactg ggtcagacat ctgtgggttc tttcaagatg ccgaatatga gatgtgtgtt
    12781 cgctggatgc agctgggcgc cttttacccc ttctccagga accacaacac catcgggacc
    12841 aggagacaag accctgtatc ctggaataaa acctttgagg atatttccag aagcgtgctg
    12901 gagaccagat acaccctgtt gccatatctc tacaccttga tgtacaaggc ccacacagag
    12961 ggcagcacag tcgtgcggcc tcttctccat gagtttgtgt cagaccggga gacctggaat
    13021 atagacaaac agttcctgct gggtccagcc tttctagtca gccctgtgct agaacctaat
    13081 gccagaacag ttgcagcata ttttcccaaa gcccgctggt atgactacta cacgggcgta
    13141 gatatcaatg caaggggaga gtggaagacc ttgcaagccc ctcttgagta cattaatctt
    13201 catgttcgtg ggggctacat tctgccatgg caggagcctg ccatgaacac ccagttaagc
    13261 cggaagaagt caatgggcct caaggctgcg ttgaatgatg agggacttgc agaaggctgg
    13321 ctcttctggg atgatggaaa aagcatcaat atcaccaatc agtactactt ggccaggttt
    13381 tctgtcagcc agaatacatt gcagacacat gaaatgttta acaactacat cactggcaca
    13441 gtacccttgt atctaggcta cattgaaatc tggggattat ccagtccttc cattaccagt
    13501 gtgaggatct ctgggaaaaa tcttaatgaa gaagtcttag ctgactacaa caccacaacc
    13561 cagatattac gtgtcaatgt gacagacaaa aatatcagcc tgcatgcttt ccagtcactg
    13621 acgtggagct agctcttcat aatgttttaa agcaagatac tatgaacaga ttttaaacta
    13681 cttcataatg atataattgt tgtatatcat caattgtttc attcccagta tgactaggat
    13741 attttatggg ttttattttg ttattttttt tgtgtgtata tgactcccaa agataatatc
    13801 tctaatgtac ctgtgtaatt agtgtggtat atatggttca ttatatgaca ttcattgaaa
    13861 catgaagatg gaagtgattc atgttgaagt gtgtatgtgt gtgtatgaag gagtatgtgt
    13921 gtgtgtgtgt gtgtgtgtgt gtgtgtgtct gtgtctgtgt gtctgtgtgt aggggattca
    13981 aatgttttcc taaagataca acagatatct tgtcatggca gctcccattt gaagctaagt
    14041 aaaaccttaa gaagtatgca gaagaaactt ccgcaagttg gtatgggaga ggagactaat
    14101 atgctgagag tttaatggag gaagaaggca aaggacagaa aaggaaggaa gcagtaaaaa
    14161 tgtgaagcaa aggtaggcaa cagtaagaga cggtcatcct caagagggag cattgcgagg
    14221 aggggaaaag aggagtcagt gcactgtaag gagaatcgtg ggttggagaa agtattaaca
    14281 ttcaggaggg ctatgaggag attaaatagg gagaactgaa agaaggagtt agatatacaa
    14341 aacaagttgt ttttatagaa gcatgctttg aagtgtataa attttatttg ttgacatctc
    14401 atgtacataa caacagttca cacaaacatc tctgatttaa atgccacaga aaaataaagc
    14461 agtgaaattg aaagaca
//
