LOCUS       NM_001108644             881 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus microfibril associated protein 5 (Mfap5), mRNA.
ACCESSION   NM_001108644 XM_001060323 XM_342750
VERSION     NM_001108644.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 881)
  AUTHORS   Hofling,C., Rossner,S., Flachmeyer,B., Krueger,M., Hartig,W. and
            Michalski,D.
  TITLE     Tricellulin, alpha-Catenin and Microfibrillar-Associated Protein 5
            Exhibit Concomitantly Altered Immunosignals along with Vascular,
            Extracellular and Cytoskeletal Elements after Experimental Focal
            Cerebral Ischemia
  JOURNAL   Int J Mol Sci 24 (15), 11893 (2023)
   PUBMED   37569268
  REMARK    GeneRIF: Tricellulin, alpha-Catenin and Microfibrillar-Associated
            Protein 5 Exhibit Concomitantly Altered Immunosignals along with
            Vascular, Extracellular and Cytoskeletal Elements after
            Experimental Focal Cerebral Ischemia.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 881)
  AUTHORS   Barallobre-Barreiro,J., Oklu,R., Lynch,M., Fava,M., Baig,F.,
            Yin,X., Barwari,T., Potier,D.N., Albadawi,H., Jahangiri,M.,
            Porter,K.E., Watkins,M.T., Misra,S., Stoughton,J. and Mayr,M.
  TITLE     Extracellular matrix remodelling in response to venous
            hypertension: proteomics of human varicose veins
  JOURNAL   Cardiovasc Res 110 (3), 419-430 (2016)
   PUBMED   27068509
REFERENCE   3  (bases 1 to 881)
  AUTHORS   Abonnenc,M., Nabeebaccus,A.A., Mayr,U., Barallobre-Barreiro,J.,
            Dong,X., Cuello,F., Sur,S., Drozdov,I., Langley,S.R., Lu,R.,
            Stathopoulou,K., Didangelos,A., Yin,X., Zimmermann,W.H., Shah,A.M.,
            Zampetaki,A. and Mayr,M.
  TITLE     Extracellular matrix secretion by cardiac fibroblasts: role of
            microRNA-29b and microRNA-30c
  JOURNAL   Circ Res 113 (10), 1138-1147 (2013)
   PUBMED   24006456
REFERENCE   4  (bases 1 to 881)
  AUTHORS   Combs,M.D., Knutsen,R.H., Broekelmann,T.J., Toennies,H.M.,
            Brett,T.J., Miller,C.A., Kober,D.L., Craft,C.S., Atkinson,J.J.,
            Shipley,J.M., Trask,B.C. and Mecham,R.P.
  TITLE     Microfibril-associated glycoprotein 2 (MAGP2) loss of function has
            pleiotropic effects in vivo
  JOURNAL   J Biol Chem 288 (40), 28869-28880 (2013)
   PUBMED   23963447
REFERENCE   5  (bases 1 to 881)
  AUTHORS   Lemaire,R., Bayle,J., Mecham,R.P. and Lafyatis,R.
  TITLE     Microfibril-associated MAGP-2 stimulates elastic fiber assembly
  JOURNAL   J Biol Chem 282 (1), 800-808 (2007)
   PUBMED   17099216
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473964.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_342750.3, XM_001060323.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: FQ229611.1, FM103833.1 [ECO:0000331]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..881
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..881
                     /gene="Mfap5"
                     /note="microfibril associated protein 5"
                     /db_xref="GeneID:362429"
                     /db_xref="RGD:1307919"
     exon            1..89
                     /gene="Mfap5"
                     /inference="alignment:Splign:2.1.0"
     exon            90..145
                     /gene="Mfap5"
                     /inference="alignment:Splign:2.1.0"
     exon            146..205
                     /gene="Mfap5"
                     /inference="alignment:Splign:2.1.0"
     CDS             148..648
                     /gene="Mfap5"
                     /note="microfibrillar associated protein 5"
                     /codon_start=1
                     /product="microfibrillar-associated protein 5 precursor"
                     /protein_id="NP_001102114.1"
                     /db_xref="GeneID:362429"
                     /db_xref="RGD:1307919"
                     /translation="MLVFGQKALLLVVALSIPSDWLPLGVSGQRGDDVPETFTDDPNL
                     VNDPSTDDTVLADITPSTDDLASAGDKNTTAECRDEKFACTRLYSVHRPVRQCVHQAC
                     FTSLRRMYIINNEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPPCENMNL
                     QRPDGP"
     exon            206..241
                     /gene="Mfap5"
                     /inference="alignment:Splign:2.1.0"
     exon            242..274
                     /gene="Mfap5"
                     /inference="alignment:Splign:2.1.0"
     exon            275..307
                     /gene="Mfap5"
                     /inference="alignment:Splign:2.1.0"
     exon            308..343
                     /gene="Mfap5"
                     /inference="alignment:Splign:2.1.0"
     exon            344..373
                     /gene="Mfap5"
                     /inference="alignment:Splign:2.1.0"
     exon            374..461
                     /gene="Mfap5"
                     /inference="alignment:Splign:2.1.0"
     exon            462..535
                     /gene="Mfap5"
                     /inference="alignment:Splign:2.1.0"
     exon            536..881
                     /gene="Mfap5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agatttccag gtgcaagaag acaaggttgc cccagagaag cagtcgcatc aaggtgagcc
       61 agccccctaa gtcactaaga cagactgcag acagacacac tcggcagcca gaggccacgg
      121 cggacagagc acagcgctgt agacaatatg ctggtctttg ggcagaaggc cttgctgctt
      181 gtcgtggcac tcagcatccc ctccgactgg ctacccctag gggtcagtgg ccaacgagga
      241 gatgacgtac ccgagacatt cacagatgac cctaatctgg tgaatgatcc ttctacagac
      301 gatacagttc tggcggatat cacaccttcc acggatgacc tggcctcagc tggtgacaaa
      361 aatactactg cagagtgccg ggatgagaag tttgcttgta caagactgta ctctgtccat
      421 cggcccgtca gacagtgtgt gcaccaggcc tgcttcacca gtttacgtcg catgtacatc
      481 atcaataatg agatctgttc ccggcttgtc tgtaaagaac acgaggccat gaaagatgag
      541 ctttgccggc agatggcagg cctgcctcca aggcgactcc gccgctccaa ctacttccga
      601 cttcctccct gtgaaaatat gaacttacag agacccgatg gtccgtgatc accaaggaag
      661 aacgaagaaa gtgtggatga gggaatccga aattccttct actccaaccg ctgccatctg
      721 tcccgtagac gtgtattttt aaactaagcc ctttgcaatg tcccggcttc ctaccctact
      781 ctgtaatttt cactggaact ggtaacgttt gtctcgtttc gcaatacagt gtctccattg
      841 ttgtacgggc tcgctgatat ctggtatggg agacaaggtg g
//
