LOCUS       NM_001107989            1034 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus microfibril associated protein 2 (Mfap2), mRNA.
ACCESSION   NM_001107989 XM_001072310 XM_233602
VERSION     NM_001107989.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1034)
  AUTHORS   Collin GB, Hubmacher D, Charette JR, Hicks WL, Stone L, Yu M,
            Naggert JK, Krebs MP, Peachey NS, Apte SS and Nishina PM.
  TITLE     Disruption of murine Adamtsl4 results in zonular fiber detachment
            from the lens and in retinal pigment epithelium dedifferentiation
  JOURNAL   Hum Mol Genet 24 (24), 6958-6974 (2015)
   PUBMED   26405179
REFERENCE   2  (bases 1 to 1034)
  AUTHORS   Hubmacher D, Reinhardt DP, Plesec T, Schenke-Layland K and Apte SS.
  TITLE     Human eye development is characterized by coordinated expression of
            fibrillin isoforms
  JOURNAL   Invest Ophthalmol Vis Sci 55 (12), 7934-7944 (2014)
   PUBMED   25406291
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1034)
  AUTHORS   Craft CS, Pietka TA, Schappe T, Coleman T, Combs MD, Klein S,
            Abumrad NA and Mecham RP.
  TITLE     The extracellular matrix protein MAGP1 supports thermogenesis and
            protects against obesity and diabetes through regulation of
            TGF-beta
  JOURNAL   Diabetes 63 (6), 1920-1932 (2014)
   PUBMED   24458361
REFERENCE   4  (bases 1 to 1034)
  AUTHORS   Zheng Q, Chen S, Chen Y, Lyga J, Wyborski R and Santhanam U.
  TITLE     Investigation of age-related decline of microfibril-associated
            glycoprotein-1 in human skin through immunohistochemistry study
  JOURNAL   Clin Cosmet Investig Dermatol 6, 317-323 (2013)
   PUBMED   24353434
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1034)
  AUTHORS   Werneck CC, Vicente CP, Weinberg JS, Shifren A, Pierce RA,
            Broekelmann TJ, Tollefsen DM and Mecham RP.
  TITLE     Mice lacking the extracellular matrix protein MAGP1 display delayed
            thrombotic occlusion following vessel injury
  JOURNAL   Blood 111 (8), 4137-4144 (2008)
   PUBMED   18281502
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473968.1.
            
            [WARNING] On Jun 14, 2023 this sequence was replaced by
            NM_001107989.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_233602.4, XM_001072310.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5756307,
                              SAMEA5760384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1034
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..1034
                     /gene="Mfap2"
                     /note="microfibril associated protein 2"
                     /db_xref="GeneID:313662"
                     /db_xref="RGD:1306031"
     exon            1..41
                     /gene="Mfap2"
                     /inference="alignment:Splign:2.1.0"
     exon            42..116
                     /gene="Mfap2"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..631
                     /gene="Mfap2"
                     /note="microfibrillar-associated protein 2"
                     /codon_start=1
                     /product="microfibrillar-associated protein 2 precursor"
                     /protein_id="NP_001101459.1"
                     /db_xref="GeneID:313662"
                     /db_xref="RGD:1306031"
                     /translation="MAMRAACLFLLFLPGLLAQGQYDLDPLPPFPDHVQYNHYGDQIE
                     NADYYDYQEVSSRPPEEQFQSQQQVPQEVIPAPTPELPAAGDQDTEPTEPGPLDCREE
                     QYPCTRLYSIHKPCKQCLNEVCFYSLRRVYVVNKEICVRTVCAHEELLRADLCRDKFS
                     KCGVIANSGLCQSVAASCARSCGGC"
     exon            117..203
                     /gene="Mfap2"
                     /inference="alignment:Splign:2.1.0"
     exon            204..230
                     /gene="Mfap2"
                     /inference="alignment:Splign:2.1.0"
     exon            231..311
                     /gene="Mfap2"
                     /inference="alignment:Splign:2.1.0"
     exon            312..365
                     /gene="Mfap2"
                     /inference="alignment:Splign:2.1.0"
     exon            366..453
                     /gene="Mfap2"
                     /inference="alignment:Splign:2.1.0"
     exon            454..527
                     /gene="Mfap2"
                     /inference="alignment:Splign:2.1.0"
     exon            528..1034
                     /gene="Mfap2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actctcagct gcactagagc acagcgcaga ggccccaaca gctgccctca acgccccact
       61 gcctcctcac ctcatggcca tgagagctgc ctgcctcttc ctgctcttct tgcctggcct
      121 gctggctcag ggccaatacg acctggatcc tctcccgccg ttcccggacc atgtccagta
      181 caaccactat ggcgaccaga tagagaacgc agactactat gactaccaag aagtgagttc
      241 tcggccccct gaggaacagt tccagtccca gcagcaagta ccacaggaag ttatcccagc
      301 tcctacccca gaactgccag ctgcagggga ccaggacacc gagcccacgg agcctggccc
      361 tcttgactgc cgtgaagaac agtacccatg tacccgcctc tactccatcc acaagccttg
      421 taaacagtgt ctcaatgagg tctgcttcta cagcctccga agagtatatg tggtcaacaa
      481 ggaaatatgt gtccgcacag tctgtgccca tgaggaactt ctccgagctg acctgtgccg
      541 agacaagttc tccaagtgtg gtgtgatagc caacagtggc ctgtgccagt ctgtggctgc
      601 ctcctgtgcc aggagctgtg ggggctgcta gggtggagct ggtgcgagat tcgagccctg
      661 gacccagctc ggatccacct caggccctgc ctgacctggt gctttctctc ccatcttgcc
      721 ctccctttca tcccggacat cagtgggctg ctgccctggg gagtgtgggc atagctgcct
      781 tgggcccctt cccagcctgt ggccatccct aagtgggggc tcctgactgt ccagtctcca
      841 ccccttaatg gggttcatcc aaggcctctt tgtgaggcct ggggttctca ctgtgccttc
      901 tcagtgcctg ggggcagtcc tcctcagtct cctcaggtag gctgtgcccc ttacccagct
      961 ggtctgcttg gatttcccac gcccccaggc atggatcacc tgttttatac aaaataataa
     1021 agtttttaca aaag
//
