LOCUS       NM_001008283             930 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus methyltransferase 23, arginine (Mettl23), mRNA.
ACCESSION   NM_001008283 XM_213557
VERSION     NM_001008283.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 930)
  AUTHORS   Reiff,R.E., Ali,B.R., Baron,B., Yu,T.W., Ben-Salem,S.,
            Coulter,M.E., Schubert,C.R., Hill,R.S., Akawi,N.A., Al-Younes,B.,
            Kaya,N., Evrony,G.D., Al-Saffar,M., Felie,J.M., Partlow,J.N.,
            Sunu,C.M., Schembri-Wismayer,P., Alkuraya,F.S., Meyer,B.F.,
            Walsh,C.A., Al-Gazali,L. and Mochida,G.H.
  TITLE     METTL23, a transcriptional partner of GABPA, is essential for human
            cognition
  JOURNAL   Hum Mol Genet 23 (13), 3456-3466 (2014)
   PUBMED   24501276
REFERENCE   2  (bases 1 to 930)
  AUTHORS   Cloutier,P., Lavallee-Adam,M., Faubert,D., Blanchette,M. and
            Coulombe,B.
  TITLE     A newly uncovered group of distantly related lysine
            methyltransferases preferentially interact with molecular
            chaperones to regulate their activity
  JOURNAL   PLoS Genet 9 (1), e1003210 (2013)
   PUBMED   23349634
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC086594.1.
            
            On Dec 16, 2004 this sequence version replaced XM_213557.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086594.1, SRR8487226.52506.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132264
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..930
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.2"
     gene            1..930
                     /gene="Mettl23"
                     /gene_synonym="RGD1306284"
                     /note="methyltransferase 23, arginine"
                     /db_xref="GeneID:287918"
                     /db_xref="RGD:1306284"
     exon            1..155
                     /gene="Mettl23"
                     /gene_synonym="RGD1306284"
                     /inference="alignment:Splign:2.1.0"
     CDS             72..749
                     /gene="Mettl23"
                     /gene_synonym="RGD1306284"
                     /EC_number="2.1.1.319"
                     /note="methyltransferase-like protein 23; probable
                     methyltransferase-like protein 23; methyltransferase like
                     23"
                     /codon_start=1
                     /product="histone-arginine methyltransferase METTL23"
                     /protein_id="NP_001008284.1"
                     /db_xref="GeneID:287918"
                     /db_xref="RGD:1306284"
                     /translation="MAGARLFRFRDEPGPGADPTVLEVRVPQVLHVQYGMYVWPCAVV
                     LAQYLWFHRRVLPGKAVLEIGAGVSLPGILAAKCGAKVTLSDSPELPHCLDICWQSCQ
                     MNNLPQVQIVGLTWGHISKDTLSLPPQDIILGSDVFFEPEDFESILATVYFLMQKNPK
                     VQFWSTYQVRSADWSLEGLLYKWDMRCVHIPLESFDADKEDIAESTLPGRHTIEMLII
                     SFAKDSS"
     exon            156..260
                     /gene="Mettl23"
                     /gene_synonym="RGD1306284"
                     /inference="alignment:Splign:2.1.0"
     exon            261..498
                     /gene="Mettl23"
                     /gene_synonym="RGD1306284"
                     /inference="alignment:Splign:2.1.0"
     exon            499..583
                     /gene="Mettl23"
                     /gene_synonym="RGD1306284"
                     /inference="alignment:Splign:2.1.0"
     exon            584..904
                     /gene="Mettl23"
                     /gene_synonym="RGD1306284"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgccctggag cccctgagca ccgcccctta acccggcgtc cctggacacc cctccgtgtg
       61 agctcggcct catggccgga gcccggctct ttcggttccg ggacgagcca ggccccggag
      121 ccgacccgac cgtgctggag gtccgcgtcc cgcaggtcct gcatgtccag tatgggatgt
      181 atgtttggcc ctgtgctgta gtcctggccc aatacctgtg gtttcacaga agagttctgc
      241 caggcaaagc tgtcttagag attggagctg gagtgagcct tccaggaatt ttggctgcca
      301 aatgtggtgc taaagtaaca ctatctgaca gcccagagct tcctcattgt ctggatattt
      361 gttggcaaag ttgccagatg aataacctgc cacaggtgca aattgtagga ctgacgtggg
      421 gccacatatc aaaggacact ttgtcattgc caccacaaga catcattctt ggatctgatg
      481 ttttctttga accagaagac tttgaaagca ttttagccac agtatacttt ctgatgcaga
      541 agaatcccaa agttcaattc tggtctacat accaggtcag aagtgctgac tggtcactgg
      601 aaggcttgct ctacaagtgg gatatgaggt gtgtgcacat tcctctggag tcttttgatg
      661 cagacaagga agatatagca gagtctaccc ttccaggaag acatactatt gaaatgctga
      721 tcatctcctt tgcaaaggat agttcctgaa tgaattatac ctcaagctat tctgggacaa
      781 tgtctaaata acatggcata aagatgaatt atcttgagaa aactcagcgg gtgcaagtct
      841 taatgctgtg atgtcatgcc tacggccaac atttaacttc aacaaaatta aacattgaaa
      901 aggaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
