LOCUS       NM_001398557            1355 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus methyltransferase 22, Kin17 lysine (Mettl22),
            mRNA.
ACCESSION   NM_001398557
VERSION     NM_001398557.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Cloutier,P., Lavallee-Adam,M., Faubert,D., Blanchette,M. and
            Coulombe,B.
  TITLE     A newly uncovered group of distantly related lysine
            methyltransferases preferentially interact with molecular
            chaperones to regulate their activity
  JOURNAL   PLoS Genet 9 (1), e1003210 (2013)
   PUBMED   23349634
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360172.254637.1,
                                           SRR26360194.128334.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-91                JAXUCZ010000010.1  7637183-7637273     c
            92-227              JAXUCZ010000010.1  7633768-7633903     c
            228-590             JAXUCZ010000010.1  7630565-7630927     c
            591-631             JAXUCZ010000010.1  7629335-7629375     c
            632-776             JAXUCZ010000010.1  7629104-7629248     c
            777-848             JAXUCZ010000010.1  7627859-7627930     c
            849-902             JAXUCZ010000010.1  7627444-7627497     c
            903-983             JAXUCZ010000010.1  7626391-7626471     c
            984-1086            JAXUCZ010000010.1  7624154-7624256     c
            1087-1255           JAXUCZ010000010.1  7621992-7622160     c
            1256-1355           JAXUCZ010000010.1  7620279-7620378     c
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..1355
                     /gene="Mettl22"
                     /gene_synonym="RGD1311433"
                     /note="methyltransferase 22, Kin17 lysine"
                     /db_xref="GeneID:287054"
                     /db_xref="RGD:1311433"
     exon            1..91
                     /gene="Mettl22"
                     /gene_synonym="RGD1311433"
                     /inference="alignment:Splign:2.1.0"
     exon            92..227
                     /gene="Mettl22"
                     /gene_synonym="RGD1311433"
                     /inference="alignment:Splign:2.1.0"
     CDS             110..1291
                     /gene="Mettl22"
                     /gene_synonym="RGD1311433"
                     /note="methyltransferase like 22"
                     /codon_start=1
                     /product="methyltransferase-like protein 22"
                     /protein_id="NP_001385486.1"
                     /db_xref="GeneID:287054"
                     /db_xref="RGD:1311433"
                     /translation="MGPAMDEVTFKSDTVLSDVHLYTPNQRHLMVRLNGMGQPVFLSQ
                     FKLLWSQDSWTDSGAEDNGPRAVSTEETPPAGSGSGHSHEDLSLQAEDDNTIQEGLSV
                     PLDEDGDLDVVRRPRAASDPNPAEPARDKVHPMILEQEEDDLVGDQARESCPYSIIKI
                     EHTMATPLEDVGKQVWRGALLLADYILFRRDLFQGCTVLELGAGTGLASIVAATMAHT
                     VYCTDVGTDLLAMCQRNVALNRHLAATGGGVVKVKELDWMKDDLCTDPKVPFSWSEEE
                     IADLYDHTTVLLAAEVFYDDDLTNALFHTFSRLVHRLKNACTAILSVEKRFNFTLRHL
                     DVTCEAYDHFRASLDSLEKLADGRLRFLVEPVETSFPQLLGYERIQQLELWKIVVEPA
                     A"
     exon            228..590
                     /gene="Mettl22"
                     /gene_synonym="RGD1311433"
                     /inference="alignment:Splign:2.1.0"
     exon            591..631
                     /gene="Mettl22"
                     /gene_synonym="RGD1311433"
                     /inference="alignment:Splign:2.1.0"
     exon            632..776
                     /gene="Mettl22"
                     /gene_synonym="RGD1311433"
                     /inference="alignment:Splign:2.1.0"
     exon            777..848
                     /gene="Mettl22"
                     /gene_synonym="RGD1311433"
                     /inference="alignment:Splign:2.1.0"
     exon            849..902
                     /gene="Mettl22"
                     /gene_synonym="RGD1311433"
                     /inference="alignment:Splign:2.1.0"
     exon            903..983
                     /gene="Mettl22"
                     /gene_synonym="RGD1311433"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1086
                     /gene="Mettl22"
                     /gene_synonym="RGD1311433"
                     /inference="alignment:Splign:2.1.0"
     exon            1087..1255
                     /gene="Mettl22"
                     /gene_synonym="RGD1311433"
                     /inference="alignment:Splign:2.1.0"
     exon            1256..1355
                     /gene="Mettl22"
                     /gene_synonym="RGD1311433"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggccacgcc tgcgcagaca gtccgtcatg gcggcttcct gagccctacg gcgagggttc
       61 cgcgtgggac ttcagaccag ggtcatggct ggtgcatccc agaaataaca tgggcccagc
      121 catggatgag gtcaccttca aaagcgacac tgtgctgtca gatgtccacc tgtacacccc
      181 caaccagagg cacctcatgg tgcggctgaa tggcatgggg cagccagtct tcctgtccca
      241 gttcaagctc ctgtggagtc aggactcttg gacagactca ggggctgagg acaatggtcc
      301 cagagccgtc tccacagagg agacgcctcc tgctgggtcg ggaagtggcc acagtcatga
      361 ggatttgtcc ctccaggctg aggatgacaa caccatccag gaagggttga gtgttcccct
      421 ggacgaggat ggggacctgg atgtggtgcg gagaccacgg gctgcttcag atcccaaccc
      481 agcagagccc gcaagagaca aggtacaccc catgattcta gaacaggagg aagatgacct
      541 cgtgggagac caagcacgag agagctgccc ctacagcatc atcaaaatag agcacaccat
      601 ggccacgccc ctggaggatg taggcaagca ggtgtggcgg ggcgccctgc tcctggcaga
      661 ctatatcctg ttccgaaggg atctcttcca gggatgcacc gtgctagagc ttggggcagg
      721 cacaggcctc gccagcatcg tggcggccac catggcccac accgtttact gtacagatgt
      781 cggcacagac ctcttggcca tgtgccaacg aaatgttgcc ctcaacaggc acctggctgc
      841 cactggaggt ggcgtggtta aggtcaagga gctagactgg atgaaggacg acctctgcac
      901 ggatcccaaa gtccccttca gctggtcaga agaagaaatc gctgacctgt atgaccacac
      961 cactgtgctg cttgcagctg aagtgttcta tgatgatgac ttaaccaatg ctctgtttca
     1021 cacattctcc cgactcgtcc acagactgaa aaatgcctgc accgccatct tgtcagtgga
     1081 aaaaaggttc aacttcacac tgagacactt ggacgtcacg tgtgaagcct acgatcactt
     1141 ccgtgcctcc ctggactcac tggagaagct ggctgatggc cgactgcgct tcctggtgga
     1201 gcctgtagag acctccttcc cgcagctgct cggctatgag cgcatccagc agctggagct
     1261 ctggaagatt gtggtcgagc cagcagcatg agtcacctct gtgacctctt gactattatc
     1321 ttaatgtatt tcaaataaag acaaaccctc agcca
//
