LOCUS       NM_001399451            1513 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus methyltransferase 21A, HSPA lysine (Mettl21a),
            mRNA.
ACCESSION   NM_001399451 XM_006245083
VERSION     NM_001399451.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1513)
  AUTHORS   Jakobsson,M.E., Moen,A., Bousset,L., Egge-Jacobsen,W.,
            Kernstock,S., Melki,R. and Falnes,P.O.
  TITLE     Identification and characterization of a novel human
            methyltransferase modulating Hsp70 protein function through lysine
            methylation
  JOURNAL   J Biol Chem 288 (39), 27752-27763 (2013)
   PUBMED   23921388
REFERENCE   2  (bases 1 to 1513)
  AUTHORS   Cloutier,P., Lavallee-Adam,M., Faubert,D., Blanchette,M. and
            Coulombe,B.
  TITLE     A newly uncovered group of distantly related lysine
            methyltransferases preferentially interact with molecular
            chaperones to regulate their activity
  JOURNAL   PLoS Genet 9 (1), e1003210 (2013)
   PUBMED   23349634
REFERENCE   3  (bases 1 to 1513)
  AUTHORS   Kernstock,S., Davydova,E., Jakobsson,M., Moen,A., Pettersen,S.,
            Maelandsmo,G.M., Egge-Jacobsen,W. and Falnes,P.O.
  TITLE     Lysine methylation of VCP by a member of a novel human protein
            methyltransferase family
  JOURNAL   Nat Commun 3, 1038 (2012)
   PUBMED   22948820
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Jan 7, 2022 this sequence version replaced XM_006245083.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360186.910878.1,
                                           SRR26360176.2171583.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676810 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-458               JAXUCZ010000009.1  73480882-73481339   c
            459-626             JAXUCZ010000009.1  73479971-73480138   c
            627-738             JAXUCZ010000009.1  73478761-73478872   c
            739-1513            JAXUCZ010000009.1  73471813-73472587   c
FEATURES             Location/Qualifiers
     source          1..1513
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q32"
     gene            1..1513
                     /gene="Mettl21a"
                     /gene_synonym="Fam119a; RGD1311824"
                     /note="methyltransferase 21A, HSPA lysine"
                     /db_xref="GeneID:102553119"
                     /db_xref="RGD:7651604"
     exon            1..458
                     /gene="Mettl21a"
                     /gene_synonym="Fam119a; RGD1311824"
                     /inference="alignment:Splign:2.1.0"
     exon            459..626
                     /gene="Mettl21a"
                     /gene_synonym="Fam119a; RGD1311824"
                     /inference="alignment:Splign:2.1.0"
     CDS             480..1136
                     /gene="Mettl21a"
                     /gene_synonym="Fam119a; RGD1311824"
                     /note="protein N-lysine methyltransferase METTL21A-like;
                     methyltransferase like 21A; family with sequence
                     similarity 119, member A"
                     /codon_start=1
                     /product="protein N-lysine methyltransferase METTL21A"
                     /protein_id="NP_001386380.1"
                     /db_xref="GeneID:102553119"
                     /db_xref="RGD:7651604"
                     /translation="MALVPYEESMSIGLQKLHKPLATFSFANHTIQIRQDWGRLGVAA
                     VVWDAAIVLSTYLEMGAVELRGCSAVELGAGTGLVGIVAALLGAHVTITDRKVALEFL
                     KSNVEANLPPHIQPKVVVKELTWGQNLDSFSPGEFDLILGADIIYLEDTFTDLLQTLG
                     HLCSNNSVILLACRIRYERDNNFLTMLERQFTVSKVHYDPEKDVHIYKAQKRKQREDL
                     "
     exon            627..738
                     /gene="Mettl21a"
                     /gene_synonym="Fam119a; RGD1311824"
                     /inference="alignment:Splign:2.1.0"
     exon            739..1513
                     /gene="Mettl21a"
                     /gene_synonym="Fam119a; RGD1311824"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctgggtgtg ggcgtggagc gacgcgagcg ccggagtcgg ctgcacgtgg ttcggttcaa
       61 aacccggcct gggcgccgca cgtctactcc ccacccgcgc cttggttaga gatgctcagt
      121 ggtgattttc ccacttcatg gccaccgaac gcggtgactc cgcttagtac tctactttgc
      181 tccgcatccg tgggagccaa cgttgccggc taaccgcaag atcgaaccaa gagctcagcc
      241 ggtgcaaggc ggtggcgttt ctccctcgca aggcacccac aactctgcgc actcgccctc
      301 cctggcgccc tacagctgtg gggccctacg tagacaggaa ccacctggcg tgggttaggg
      361 ggaagcagcg cttctggaaa agcggaccgg aaacccgcgt ctcccttccc ggaccagctt
      421 ccgcctgcct tctgccaatc tggcctttaa gcgacgaggt ctcagcagag ttagaagaaa
      481 tggccctggt accgtatgag gagagcatgt caatagggct ccagaaactc cataagcctc
      541 ttgccacctt ctcgtttgca aaccacacca tccagatccg tcaggactgg gggcgactgg
      601 gagtggctgc agtggtttgg gatgcggcca ttgttctttc cacgtatctg gagatgggtg
      661 ccgtggagct caggggctgc tctgccgtgg agctgggagc tggcacaggg ctggtgggca
      721 tcgtggctgc gctgctgggt gctcatgtga ctatcacgga ccgaaaagta gcgttagaat
      781 ttcttaagtc aaatgttgag gccaacttac ctccccatat ccaacctaag gtggttgtta
      841 aggagctgac ttggggacaa aatttggaca gtttttcacc tggagaattt gatctcatac
      901 ttggagctga tatcatatac ttagaagata ccttcacaga ccttcttcaa acactgggac
      961 atctctgtag caacaactct gtgattcttc tagcttgccg aatccgctat gaacgggata
     1021 ataacttctt aacaatgctg gagaggcagt tcactgtgag taaggttcac tacgatcctg
     1081 agaaggatgt acacatttac aaagcacaga agagaaagca gagggaggac ttgtagtggg
     1141 cagtattttc taagaatcga atgcatcagt taaggtctta cagctagaac tcttagcggt
     1201 gttaatgacg tagcagactg caagtcattc ctctcagagc tgctcaagga acaaagcacg
     1261 tgtgtacttt gtagacaatg ccttgcctca ttgccggaac tgtcagtcag attgactgta
     1321 gatggacatg tgaagtttgg ctggtgttct ttgctttgcc ctgtgtgctc acttggtaag
     1381 caatttccac tgataaagaa tgatatgaag gtgtccctaa actggtgagt cagtcatata
     1441 ttctgggatg tattttgtct tagtttcctt gtctgttgag tgtaaacaga cttattatat
     1501 gtcttccctg aaa
//
