LOCUS       XM_039110229            2205 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus maternal embryonic leucine zipper
            kinase (Melk), transcript variant X2, mRNA.
ACCESSION   XM_039110229
VERSION     XM_039110229.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051340.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2205
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2205
                     /gene="Melk"
                     /note="maternal embryonic leucine zipper kinase; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 6 ESTs, 4 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 16 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:362510"
                     /db_xref="RGD:1308974"
     CDS             274..2205
                     /gene="Melk"
                     /codon_start=1
                     /product="maternal embryonic leucine zipper kinase isoform
                     X1"
                     /protein_id="XP_038966157.1"
                     /db_xref="GeneID:362510"
                     /db_xref="RGD:1308974"
                     /translation="MKDYDELLKYYELYETIGTGGFAKVKLACHILTGEMVAIKIMDK
                     NALGSDLPRVKTEIDALKNLRHQHICQLYHVLETKNKIFMVLEYCPGGELFDYIISQD
                     RLSEEETRVIFRQILSAVAYVHSQGYAHRDLKPENLLFDENHKLKLIDFGLCAKPKGN
                     KDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALY
                     KKIMRGKYEVPKWLSPSSILLLQQMLQVDPKRRISMKNLLNHPWILQDYSCPIEWQSK
                     ASLTHLDEDCITELSVHHRNSRQTMEDLISSWQYDHLTATYLLLLAKKARGKPARLQL
                     LSFSGGTTSTTPKSKNLSLEDMSTSGDSCVAGLIDYELCEDNLLAPQTPQFTKHWAES
                     NHVECESPTPVVCRALANKLKDKENVCTPKSSVKNQEQFVFSEPKIPVSRNQYKREIL
                     TSPTQFTAPAKARTQCLRETQVRTPVNSAGADTLTTNVISPERRCRSMEVDLNQAHME
                     DTPKRKGTNVFGSLERGLDKVLTALTRNKKKGSAKDGPRRRKLHYNVTTTRLVNPDQL
                     LNEIMAILPKKNVDFVQKGYTLKCQTQSDFGKVTMQFELEVCQLQRPDVVGIRRQRLK
                     GDAWVYKRLVEDILSGCKM"
ORIGIN      
        1 gttttgattc ccttggcggg cggaaactgc tggaacttga atcctgcaga gattcccacc
       61 gactgttccg gctttgctag gctctgctgc cggctgcttc accctctgtc ctgttcggtc
      121 ctgccaggcc cgctgccctt tagccaaagt ggtccttgag ttctggatac ttctgccata
      181 gcttcctgag acctggggat acaggcgtga gtgctcccca ctcctggctc acgaggttct
      241 tgttgtgatt ttgaataagc ttccagctgg actatgaaag attatgacga gctccttaaa
      301 tactatgaat tatatgaaac tattgggaca ggtggctttg caaaggtcaa acttgcctgt
      361 catatcctca ctggagaaat ggtagctata aaaatcatgg ataagaatgc actagggagc
      421 gatttgcccc gagtcaaaac tgaaattgat gccctgaaga atctgagaca tcagcatata
      481 tgtcagctct accatgtgct agagacaaag aacaaaatat tcatggtgct tgagtactgt
      541 ccaggaggag agctgtttga ctacatcatc tcccaggatc gcctgtcgga agaggagacc
      601 cgagtcatct tccgccagat cctgtctgca gttgcatatg tgcacagcca gggctatgcc
      661 cacagggacc tcaagccaga aaatttattg tttgacgaaa atcataagct aaagctgatt
      721 gactttggtc tctgtgcaaa acccaagggc aacaaggact accatctaca gacatgctgt
      781 gggagtctgg cgtatgcagc acctgaacta atacaaggga aatcgtatct tggatcagag
      841 gcagatgttt ggagcatggg catcctccta tatgtgctta tgtgtggatt cctcccgttt
      901 gatgatgata atgtcatggc tttgtacaag aagataatga gagggaagta tgaagttccc
      961 aagtggctgt ctcccagcag catcctgctt ctccagcaga tgcttcaggt ggacccaaag
     1021 agacggattt ctatgaaaaa tctcttgaac catccctgga tcctgcaaga ttacagctgt
     1081 cccattgagt ggcaaagcaa ggcttctttg actcaccttg atgaggattg cataacagag
     1141 ctttctgtac atcaccgcaa cagcaggcaa acaatggagg atttaatttc gtcgtggcag
     1201 tatgatcacc tcacagccac ctaccttctg cttctagcca agaaggctcg agggaagcca
     1261 gctcgtctgc agcttctgtc cttctctggt gggaccacca gcaccactcc aaagtcaaag
     1321 aacctgagcc tggaagatat gtccacaagt ggcgatagct gtgtggctgg attaatagac
     1381 tatgaattgt gtgaagataa tttactagct ccccagacac cacagtttac caaacactgg
     1441 gcagaatcaa atcatgttga atgtgaatca ccaactccag tggtatgcag agcactggcc
     1501 aataagttaa aggacaaaga gaatgtgtgc actcccaagt cttctgtgaa gaatcaagag
     1561 caattcgtgt tttctgagcc gaagattcca gttagtcgga accagtataa gagagaaata
     1621 ctcacctcac caacccagtt cacagcacct gcaaaagcta gaacgcagtg cctgagagaa
     1681 acccaggtta gaacgccggt gaattccgca ggagcagaca cgctaacgac aaatgtcatt
     1741 agccctgaga ggaggtgccg ttcaatggaa gtggatctca accaggcaca catggaggat
     1801 acccctaaaa ggaaaggaac caatgtgttt gggagccttg agagaggact ggataaggtt
     1861 ctcactgcac ttacaaggaa caagaagaag ggctctgcca aagatgggcc aagaaggcga
     1921 aagctgcact acaatgtgac tacaactaga ctggtgaatc ccgaccagct cctgaacgaa
     1981 atcatggcta ttcttccaaa gaagaacgtg gacttcgtgc agaaaggtta cacactgaag
     2041 tgtcagacac agtctgattt tggcaaagtg acaatgcagt ttgaactgga agtgtgccag
     2101 ctgcagagac ctgacgtggt gggtatccgg agacagcggc tgaagggtga tgcctgggtt
     2161 tacaagagat tagtggaaga tatcttgtct ggctgcaaga tgtaa
//
