LOCUS       NM_001399601            1931 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus Meis homeobox 3 (Meis3), transcript variant 1,
            mRNA.
ACCESSION   NM_001399601 XM_006228348
VERSION     NM_001399601.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1931)
  AUTHORS   Liu,J., Wang,Y., Birnbaum,M.J. and Stoffers,D.A.
  TITLE     Three-amino-acid-loop-extension homeodomain factor Meis3 regulates
            cell survival via PDK1
  JOURNAL   Proc Natl Acad Sci U S A 107 (47), 20494-20499 (2010)
   PUBMED   21059917
REFERENCE   2  (bases 1 to 1931)
  AUTHORS   Shim,S., Kim,Y., Shin,J., Kim,J. and Park,S.
  TITLE     Regulation of EphA8 gene expression by TALE homeobox transcription
            factors during development of the mesencephalon
  JOURNAL   Mol Cell Biol 27 (5), 1614-1630 (2007)
   PUBMED   17178831
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jan 12, 2022 this sequence version replaced XM_006228348.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC160854.1, SRR26643299.1291.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-182               JAXUCZ010000001.1  85990341-85990522
            183-364             JAXUCZ010000001.1  85992306-85992487
            365-524             JAXUCZ010000001.1  85992626-85992785
            525-575             JAXUCZ010000001.1  85992879-85992929
            576-929             JAXUCZ010000001.1  85993741-85994094
            930-1041            JAXUCZ010000001.1  85996638-85996749
            1042-1190           JAXUCZ010000001.1  85996884-85997032
            1191-1267           JAXUCZ010000001.1  85998370-85998446
            1268-1326           JAXUCZ010000001.1  85998617-85998675
            1327-1410           JAXUCZ010000001.1  85999242-85999325
            1411-1480           JAXUCZ010000001.1  85999845-85999914
            1481-1931           JAXUCZ010000001.1  86000423-86000873
FEATURES             Location/Qualifiers
     source          1..1931
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..1931
                     /gene="Meis3"
                     /gene_synonym="Mrg2"
                     /note="Meis homeobox 3"
                     /db_xref="GeneID:361514"
                     /db_xref="RGD:1308532"
     exon            1..182
                     /gene="Meis3"
                     /gene_synonym="Mrg2"
                     /inference="alignment:Splign:2.1.0"
     CDS             171..1460
                     /gene="Meis3"
                     /gene_synonym="Mrg2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     Meis1, myeloid ecotropic viral integration site 1 homolog
                     3; myeloid ecotropic viral integration site-related gene
                     2; homeobox protein Meis3"
                     /codon_start=1
                     /product="homeobox protein Meis3 isoform 1"
                     /protein_id="NP_001386530.1"
                     /db_xref="GeneID:361514"
                     /db_xref="RGD:1308532"
                     /translation="MARRYEEPRHYPGITEHTAALASFPEAAPSVPRAPGPYGPHRPP
                     QPQGPGLDSDSLKREKDDIYGHPLFPLLALVFEKCELATCSPRDGASAGLGSPPGGDV
                     CSSDSFNEDIAAFAKQIRSERPLFSSNPELDNLMVQAIQVLRFHLLELEKVRVSHLHL
                     PHPLPLTPLSLLPIGVEAEYSLTLSTPALAPPGGPPSTPLPSQVHDLCDNFCHRYITC
                     LKGKMPIDLVIEDRDGGCREDLEDYAASCPSLPDQNTTWIRDHEDSGSVHLGTPGPSS
                     GGLASQSGDNSSDQGDGLDTSVASPSSAGEDEDLDLERRRNKKRGIFPKVATNIMRAW
                     LFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRTGQGASFN
                     PEGQSMAGYTETQPHVTVRTPGSMGMNLNLEGEWHYL"
     exon            183..364
                     /gene="Meis3"
                     /gene_synonym="Mrg2"
                     /inference="alignment:Splign:2.1.0"
     exon            365..524
                     /gene="Meis3"
                     /gene_synonym="Mrg2"
                     /inference="alignment:Splign:2.1.0"
     exon            525..575
                     /gene="Meis3"
                     /gene_synonym="Mrg2"
                     /inference="alignment:Splign:2.1.0"
     exon            576..929
                     /gene="Meis3"
                     /gene_synonym="Mrg2"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1041
                     /gene="Meis3"
                     /gene_synonym="Mrg2"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1190
                     /gene="Meis3"
                     /gene_synonym="Mrg2"
                     /inference="alignment:Splign:2.1.0"
     exon            1191..1267
                     /gene="Meis3"
                     /gene_synonym="Mrg2"
                     /inference="alignment:Splign:2.1.0"
     exon            1268..1326
                     /gene="Meis3"
                     /gene_synonym="Mrg2"
                     /inference="alignment:Splign:2.1.0"
     exon            1327..1410
                     /gene="Meis3"
                     /gene_synonym="Mrg2"
                     /inference="alignment:Splign:2.1.0"
     exon            1411..1480
                     /gene="Meis3"
                     /gene_synonym="Mrg2"
                     /inference="alignment:Splign:2.1.0"
     exon            1481..1931
                     /gene="Meis3"
                     /gene_synonym="Mrg2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgacacagg ccgggcccgt gtgagcccag gagccgccgc caccctcggc cgcgatccgc
       61 gggtcttggc cactcggaga ccccggcacc cggcggggac ctcggggacc tccggccgcg
      121 atgagcccca ggccgtgacc tcccgagccc aggacgcgcg gcgccggctc atggcccgga
      181 ggtatgagga gccgcgccac taccccggca ttaccgagca cacggcagcc ctggccagtt
      241 ttccagaggc agcaccttca gtacctcgag ctcctgggcc ctatggccca caccggccgc
      301 cccaacccca aggtccaggc ttggacagcg atagcttgaa gagagagaag gatgacatct
      361 atggacaccc cctcttccca ctcttggccc tggtctttga gaagtgtgag ctggctacat
      421 gctcgccccg tgatggggcc tcggctgggc tgggttcacc cccaggtggt gacgtctgct
      481 cctctgactc cttcaatgag gatattgctg cctttgctaa gcagatccgc tccgagaggc
      541 cgctgttctc ttccaacccg gagctggaca acctgatggt ccaggccatc caggtactcc
      601 ggttccacct gctggagctg gagaaggtga gggtgtctca cttgcacctg ccccaccccc
      661 tccctctaac tcctctctcc ctactcccca ttggagtgga agcagaatac tccctcaccc
      721 tgtccacccc agccctggct cccccgggtg gcccccccag taccccactg ccctcccagg
      781 tccacgacct gtgcgacaac ttctgtcacc gctacatcac ctgcctcaag gggaagatgc
      841 ccatagacct ggtgatcgag gatcgggatg gtggttgcag ggaggacctt gaggactacg
      901 cagcctcctg ccccagcctc ccagaccaga atactacatg gatcagagac catgaggaca
      961 gtgggtctgt acatttgggg accccaggtc catccagcgg aggcctggcc tcccagagcg
     1021 gggacaactc aagtgaccaa ggagatgggc tggacaccag cgtggcctct cccagctccg
     1081 caggagagga tgaggacctg gacctggagc gcagacggaa caagaagagg gggatcttcc
     1141 ccaaagtggc caccaacatc atgagggcct ggttgttcca gcatctctcg cacccgtacc
     1201 cctcagaaga gcaaaagaaa cagctggccc aggacaccgg gctcaccatt ctgcaggtga
     1261 acaactggtt tattaatgcc cggagacgga tagtgcagcc catgattgac cagtctaatc
     1321 gtacagggca gggtgcatct ttcaaccctg agggccagtc catggcaggc tacacagaga
     1381 ctcaaccaca tgtgacagtc aggacgccag gatcaatggg gatgaatctg aacttagaag
     1441 gagaatggca ttacctatag aggttggggt caaaaggagg gccccagcct ctgactatga
     1501 ccaccagcct tgcacctaat tggtccctgc tggtccctgg gcttcaggac ttcacctcca
     1561 aagctcccac cccattcaac gcctacctcc ctggggcccc cagaggcttg aggacccaga
     1621 gcccacttga gggtttctca agggcaaaga caaagcctca aggtcctgca cccttcttct
     1681 gccctcccct ttgcccagga cctgagctga gaactgggcc aaggtctgaa gaagatggtg
     1741 gctggggccc caatccagga cagagaagag actggggttg ggcaaggatg ggcaaggaag
     1801 gagggtcagc tggatccaat gtttgggaga atccttcatc ttcctgctct ctgcctctct
     1861 cacctccctt ctctgacatt cttctacctt tccttttttt aatgataaag tcttaaaagt
     1921 gcaaatcaaa a
//
