LOCUS       NM_022955               5523 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus multiple EGF-like-domains 6 (Megf6), mRNA.
ACCESSION   NM_022955 XM_346755
VERSION     NM_022955.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5523)
  AUTHORS   Nakayama,M., Nakajima,D., Nagase,T., Nomura,N., Seki,N. and
            Ohara,O.
  TITLE     Identification of high-molecular-weight proteins with multiple
            EGF-like motifs by motif-trap screening
  JOURNAL   Genomics 51 (1), 27-34 (1998)
   PUBMED   9693030
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB011532.1.
            
            On Dec 17, 2003 this sequence version replaced XM_346755.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB011532.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760476, SAMN11044071
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..5523
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..5523
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /note="multiple EGF-like-domains 6"
                     /db_xref="GeneID:65049"
                     /db_xref="RGD:621188"
     exon            1..353
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     CDS             235..4959
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /note="multiple epidermal growth factor-like domains
                     protein 6; EGF-like domain-containing protein 3; multiple
                     EGF-like domains protein 6; multiple epidermal growth
                     factor-like domains protein 6-like; EGF-like-domain,
                     multiple 3; multiple EGF-like domain protein 3; multiple
                     epidermal growth factor-like domains 6; epidermal growth
                     factor-like protein 3"
                     /codon_start=1
                     /product="multiple epidermal growth factor-like domains
                     protein 6 precursor"
                     /protein_id="NP_075244.1"
                     /db_xref="GeneID:65049"
                     /db_xref="RGD:621188"
                     /translation="MPVRAEARAAWRVVALALLLLPAMPAASPPLTPRPLQPSMPHVC
                     AEQKLTLVGHRQPCVQAFSRIVPVWRRTGCAQQAWCIGQERRTVYYMSYRQVYATEAR
                     TVFRCCPGWSQKPGQEGCLSDVDECASANGGCEGPCCNTVGGFYCRCPPGYQLQGDGK
                     TCQDVDECRAHNGGCQHRCVNTPGSYLCECKPGFRLHTDGRTCLAISSCTLGNGGCQH
                     QCVQLTVTQHRCQCRPQYQLQEDGRRCVRRSPCAEGNGGCMHICQELRGLAHCGCHPG
                     YQLAADRKTCEDVDECALGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEI
                     VNSCEAGNGGCSHGCSHTSTGPLCTCPRGYELDEDQKTCIDIDDCANSPCCQQACANT
                     PGGYECSCFAGYRLNTDGCGCEDVDECASGHGGCEHHCSNLAGSFQCFCEAGYRLDED
                     RRGCTSLEESVVDLDGRLPFVRPLPHIAVLRDELPRLFQDDYGAEEEAAAAELRGEHT
                     LTEKFVCLDHSFGHDCSLTCDDCRNGGTCFPGQDGCDCPEGWTGIICNETCPPDTFGK
                     NCSSPCTCQNGGTCDPVLGACRCPPGVSGAHCEDGCPKGFYGKHCRKKCHCANRGRCH
                     RLYGACLCDPGLYGRFCHLACPPWAFGPGCSEDCLCEQSHTRSCNPKDGSCSCKAGFQ
                     GERCQAECESGFFGPGCRHRCTCQPGVACDPVSGECRTQCPPGYQGEDCGQECPVGTF
                     GVNCSGSCSCVGAPCHRVTGECLCPPGKTGEDCGADCPEGRWGLGCQEICPACEHGAS
                     CNPETGTCLCLPGFVGSRCQDTCSAGWYGTGCQIRCACANDGHCDPTTGRCSCAPGWT
                     GLSCQRACDSGHWGPDCIHPCNCSAGHGNCDAVSGLCLCEAGYEGPRCEQSCRQGYYG
                     PSCEQKCRCEHGAACDHVSGACTCPAGWRGSFCEHACPAGFFGLDCDSACNCSAGAPC
                     DAVTGSCICPAGRWGPRCAQSCPPLTFGLNCSQICTCFNGASCDSVTGQCHCAPGWMG
                     PTCLQACPPGLYGKNCQHSCLCRNGGRCDPILGQCTCPEGWTGLACENECLPGHYAAG
                     CQLNCSCLHGGICDRLTGHCLCPAGWTGDKCQSSCVSGTFGVHCEEHCACRKGASCHH
                     VTGACFCPPGWRGPHCEQACPRGWFGEACAQRCLCPTNASCHHVTGECRCPPGFTGLS
                     CEQACQPGTFGKDCEHLCQCPGETWACDPASGVCTCAAGYHGTGCLQRCPSGRYGPGC
                     EHICKCLNGGTCDPATGACYCPAGFLGADCSLACPQGRFGPSCAHVCACRQGAACDPV
                     SGACICSPGKTGVRCEHGCPQDRFGKGCELKCACRNGGLCHATNGSCSCPLGWMGPHC
                     EHACPAGRYGAACLLECFCQNNGSCEPTTGACLCGPGFYGQACEHSCPSGFHGPGCQR
                     VCECQQGAPCDPVSGQCLCPAGFHGQFCEKGCESGSFGDGCLQQCNCHTGVPCDPISG
                     LCLCPPGRTGAACDLDCRRGRFGPGCALRCDCGGGADCDPISGQCHCVDSYMGPTCRE
                     VPTQISSSRPAPQHPSSRAMKH"
     exon            354..491
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            492..601
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            602..724
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            725..847
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            848..973
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1096
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1097..1219
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1220..1357
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1358..1477
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1478..1600
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1601..1774
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1775..1906
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1907..2035
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            2036..2164
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            2165..2299
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            2300..2434
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            2435..2560
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            2561..2692
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            2693..2821
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            2822..2953
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            2954..3082
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            3083..3211
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            3212..3340
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            3341..3469
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            3470..3598
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            3599..3727
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            3728..3856
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            3857..3988
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            3989..4117
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            4118..4246
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            4247..4375
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            4376..4504
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            4505..4633
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            4634..4762
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            4763..4891
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     exon            4892..5523
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      5523
                     /gene="Megf6"
                     /gene_synonym="Egfl3"
                     /note="31 a nucleotides"
ORIGIN      
        1 atcactccag gcaagtgtct ggccgcgcca agcagagcgc gaaagtctcg gagctccggg
       61 caactgctcc atccgcacct gtgggaacct cgcgtcccgc acctggcacg gctgggttgc
      121 ggtgctccgc tgtcctccgg ggtatggcgc gcgtgaagac agggtctccc ggccacaagg
      181 gccgcctgtg agtccaagag ccgaagattg agtgggagcg cgaccgcgcg cactatgcct
      241 gtccgggcgg aggcgagggc ggcttggcgc gtggtggccc tggcgctgct gctgctcccc
      301 gcaatgcctg cagcctcccc gccgctaacc ccgcgcccgc tgcagccgag catgccccac
      361 gtgtgtgcag aacagaagct gaccctggtg ggccaccgcc agccttgtgt gcaagccttc
      421 agtcgcatag tgcctgtgtg gaggaggaca ggctgcgcac agcaggcgtg gtgtattggc
      481 caagagcgca ggactgtgta ctatatgagc tacaggcagg tatatgccac agaggcccga
      541 acggtgttca ggtgctgccc tggctggagc cagaagcctg gccaggaagg ctgcctctca
      601 gatgtggacg aatgcgccag tgccaacggg ggttgcgagg gcccatgctg taacactgtg
      661 ggtggctttt actgccgctg cccacccggc taccagctgc agggtgacgg caaaacctgc
      721 caagatgtgg atgaatgtcg agcacacaat ggtggttgtc aacacaggtg tgtgaacacc
      781 cccggttctt acctctgtga atgcaaacct ggcttccggc tccacacaga tggcaggacc
      841 tgcctggcca tcagctcctg cactctggga aacggtggct gccagcacca gtgtgtacag
      901 ctcacagtga cacagcaccg ctgccagtgc cggccccagt accagctgca agaggatggc
      961 aggcgctgtg tgcggagaag cccgtgtgca gaaggcaatg gtggctgtat gcatatatgc
     1021 caggaactcc ggggccttgc ccactgtggc tgccaccccg gttaccagct tgctgcagac
     1081 cgcaaaacct gtgaagatgt ggatgaatgt gctttggggc tggcccagtg tgctcatggc
     1141 tgcctcaaca ctcagggatc ctttaagtgt gtgtgccacg caggctatga actgggcgcc
     1201 gatggccggc agtgttaccg gatcgagatg gagattgtga acagctgtga ggctggcaac
     1261 ggtgggtgct cccacggctg tagccacacc agcactgggc ccctgtgcac ctgccctcgt
     1321 ggttacgagt tggatgaaga ccagaagacc tgtatcgaca tcgacgactg cgccaactct
     1381 ccgtgctgcc agcaggcatg tgccaacacc cctggtgggt atgagtgcag ctgtttcgct
     1441 ggctaccggc tcaacacgga cggctgtggc tgtgaggatg ttgacgagtg cgcctctggt
     1501 cacggtggct gcgaacacca ctgttctaat ctggcgggct ccttccagtg cttctgtgag
     1561 gccggttacc ggttggatga ggaccgcagg ggctgcactt ccctagaaga atctgtggtg
     1621 gacctggatg gccggctgcc ctttgtgcgg cccctgcccc acattgcggt gctgagggat
     1681 gagctgcccc gactcttcca ggatgattat ggggctgagg aggaggcggc ggcagcggag
     1741 ttgcgtggag aacacacgct cactgagaag tttgtctgct tggatcactc cttcgggcat
     1801 gactgcagcc taacctgcga tgactgcagg aatgggggga cttgcttccc gggccaggac
     1861 ggctgtgact gcccagaggg ctggactgga atcatctgca atgagacttg tcctccagac
     1921 acctttggga agaattgtag ctctccctgc acctgtcaga atggtgggac ctgtgacccg
     1981 gtgttgggag cctgccgctg tcctccaggc gtcagtggag cccactgtga ggatggctgc
     2041 cccaagggct tctacggcaa acattgccgt aagaaatgcc actgtgctaa ccggggccgg
     2101 tgccaccgcc tctatggggc ctgcctctgt gacccagggc tctatggtcg tttctgccac
     2161 cttgcctgtc ctccctgggc cttcgggcca ggctgttctg aggactgcct ttgcgagcag
     2221 tcacacacaa ggtcttgcaa cccgaaggac ggtagctgct cctgcaaggc cggcttccag
     2281 ggtgagcgct gccaggcaga gtgtgagtca ggcttctttg gaccaggctg cagacaccgt
     2341 tgcacctgcc agccaggtgt ggcctgtgac cctgtgagtg gcgagtgtcg gactcagtgt
     2401 cctcctggct accaggggga agactgtggc caagagtgcc cggtgggaac atttggtgtg
     2461 aactgctcag gttcctgttc ctgcgttgga gcgccttgtc accgagtcac aggggagtgt
     2521 ctgtgcccac cagggaagac tggggaggac tgtggagctg attgtcccga gggccgttgg
     2581 gggctcggct gtcaagagat ctgccccgca tgtgagcacg gagccagctg caaccctgag
     2641 actggaacct gcctgtgtct ccctggcttt gttggtagcc gctgccagga cacttgctca
     2701 gcaggctggt acgggactgg ctgccagata aggtgtgctt gtgccaacga tgggcattgt
     2761 gacccaacca ccggacgctg tagctgtgcc cccgggtgga ctggcctcag ctgccagaga
     2821 gcctgtgaca gtggacactg ggggcccgac tgcatccacc cttgcaactg cagtgcgggc
     2881 catgggaatt gtgacgccgt cagtggcctc tgcctgtgtg aggccggcta tgaaggtcca
     2941 cggtgtgagc agtcgtgtcg ccagggatac tatgggccca gctgtgagca gaagtgcaga
     3001 tgtgagcatg gggctgcctg tgaccatgtc agtggggcct gtacctgccc agccggctgg
     3061 aggggaagct tctgtgaaca tgcctgtcct gctggcttct ttgggttaga ctgtgacagt
     3121 gcctgcaact gctctgccgg ggcaccctgt gatgctgtca ccggctcatg catctgccca
     3181 gctggccgct ggggcccacg ctgtgcccag agttgcccac ccctcacctt cgggcttaac
     3241 tgcagccaga tttgtacctg tttcaatggg gcctcctgtg actctgtcac agggcaatgc
     3301 cactgtgccc ctggctggat gggacccacc tgcctgcagg cctgccctcc tggcctgtat
     3361 ggcaagaact gtcagcattc ctgtctttgc cgcaacggag ggagatgtga ccccatcttg
     3421 ggccagtgca cgtgcccaga gggttggacc ggcttggcct gtgagaacga gtgccttcct
     3481 ggacactatg cagccggttg tcagctcaac tgcagttgcc ttcacggggg catatgtgac
     3541 cggcttaccg gccactgcct ctgcccagct ggctggactg gggacaagtg tcagagctcc
     3601 tgcgtcagtg gcacgtttgg ggttcactgt gaggaacact gtgcttgccg gaaaggtgcc
     3661 tcctgccacc atgtcacagg ggcctgcttc tgtcctccag gatggagggg cccacactgt
     3721 gagcaggcct gtccacgcgg atggtttgga gaggcctgtg ctcagcgttg cctctgccca
     3781 accaatgcct cctgccacca tgtcactggg gagtgccgct gtccacccgg ctttactggg
     3841 cttagctgtg agcaggcttg tcagcctggc acctttggaa aggactgtga gcacctgtgc
     3901 cagtgtcctg gtgagacctg ggcctgcgac cctgcttcag gggtctgcac gtgtgccgct
     3961 ggttaccatg gcaccggctg tctgcaaaga tgcccatctg ggcgctatgg gccgggctgt
     4021 gaacacattt gtaagtgtct caatggtggg acctgcgacc cagccacggg agcctgctac
     4081 tgtcctgctg ggttccttgg ggccgactgc agccttgcct gtccacaggg tcgctttggc
     4141 cccagctgtg cccacgtgtg tgcatgcagg caaggggcgg catgcgaccc ggtgtcgggg
     4201 gcttgcatct gttctcccgg gaagacgggg gtccgctgtg agcatggctg tccccaggac
     4261 cggtttggca agggctgtga actcaagtgt gcctgcagga atgggggcct gtgtcatgct
     4321 accaacggca gctgttcctg ccccctgggc tggatggggc ctcactgtga gcacgcctgc
     4381 cctgctgggc gctatggtgc tgcctgcctc ctggagtgtt tctgtcagaa caatggcagc
     4441 tgtgagccta ccacgggcgc ttgcctctgt ggccctggct tctacggtca agcttgtgaa
     4501 cactcttgcc cctccggctt ccatggacct ggttgccaga gagtttgtga gtgtcaacag
     4561 ggagccccct gtgaccctgt cagtggccag tgcctctgcc ctgctggctt ccatggccag
     4621 ttctgtgaga aggggtgtga gtcaggctct tttggagatg gctgcctgca gcagtgtaac
     4681 tgccacacgg gtgtgccctg tgatcccatc agcggcctct gcctttgccc gcctgggcgg
     4741 acaggagccg catgtgacct ggattgcaga aggggccgct ttgggccggg ctgcgccctg
     4801 cgctgtgatt gcgggggtgg ggccgactgc gaccccatca gtgggcagtg ccactgtgtg
     4861 gacagctaca tgggacccac ttgccgggaa gtgcccacac agatatcctc tagcagacca
     4921 gcaccccagc accccagcag cagggccatg aagcactaaa tcagaggaac acccacagat
     4981 gtccactact gtgttccagc ccaagggacc caggcctctg ctggagactg agaagacgca
     5041 ggtgggacat ctgagtccat gcctctcctg gaaagccatg gatctctgtg gacgcagcca
     5101 cacatcaggg ctctgtggtc atggggaaga aggcctcctt tgaacataag gaatccaggg
     5161 aagtggactg ggcctcaggc cgctgtttac atggggaccc tgcaggctgc gctgtggaat
     5221 cctggctctc ttcagggatc tggggtgggg ataagcaagg ccccacctgc ctgctaggtc
     5281 cttctggtgc taagccatgg actgctgcgg ccagccaact gtttacctgg aaatgtagtc
     5341 cagtctgtat ttatgtaagg tatttatggg caattccaca tgccgttatg accctggtca
     5401 gctggaagct gcctgatctc agaactcagg cagaaggctt tggggtgggg tggggggctt
     5461 tgccagcaag tgggattaag ggttttgtaa aacccagtga gttaaaggca cagtggtgtc
     5521 ctc
//
