LOCUS       XM_039082447            7214 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus multiple EGF-like-domains 11 (Megf11),
            transcript variant X2, mRNA.
ACCESSION   XM_039082447
VERSION     XM_039082447.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051343.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039082447.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7214
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..7214
                     /gene="Megf11"
                     /note="multiple EGF-like-domains 11; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 17
                     ESTs, 11 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 11 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:691517"
                     /db_xref="RGD:1582797"
     CDS             275..3694
                     /gene="Megf11"
                     /codon_start=1
                     /product="multiple epidermal growth factor-like domains
                     protein 11 isoform X1"
                     /protein_id="XP_038938375.1"
                     /db_xref="GeneID:691517"
                     /db_xref="RGD:1582797"
                     /translation="MAPSTVGLLVVFLLQAALALNPEDPNVCSHWESYAVTVQESYAH
                     PFDQIYYTRCADILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYENGDFCIPL
                     CTEECMHGRCVSPDTCHCEPGWGGPDCSSGCDSEHWGPHCSNRCQCQNGALCNPITGA
                     CVCAPGFRGWRCEEFCAPGTHGKGCQLLCQCHHGASCDPRTGECLCAPGYTGVYCEEL
                     CPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCP
                     CHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGTFGFRCSQRCDCHNGGQCSPATGACE
                     CEPGYKGPSCQERLCPEGLHGPGCTSPCPCDTENTISCHPVTGACTCQPGWSGHYCNE
                     SCPAGYYGNGCQLPCTCQNGADCHSITGSCTCAPGFMGEVCAVPCAAGTYGPNCSSVC
                     SCSNGGTCSPVDGSCTCREGWQGLDCSLPCPSGTWGLNCNESCVCANGAACSPFDGSC
                     ACTPGWLGDSCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTC
                     PPGRWGPNCSVSCSCENGGSCSPVDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPL
                     CVHSRGPCHHVSGICECLPGFSGALCNQVCAGGHFGQDCAQLCSCANNGTCSPIDGSC
                     QCFPGWTGKDCSQACPSGFWGSACFHTCSCHNGASCSAEDGACHCTPGWTGLFCTQRC
                     PAAFFGKDCGHICQCQNGASCDHITGKCTCRTGFSGRHCEQRCAPGTFGYGCQQLCEC
                     MNNATCDHVTGTCYCSPGFKGIRCDQAALMMDELNPYTKISPALGAERHSVGAVTGII
                     LLLFLVVVLLGLFAWRRRRQKEKGRDLAPRVSYTPAMRMTSTDYSLSDLSQSSSHAQC
                     FSNASYHTLACGGPATSQASTLDRNSPTKLSNKSLDRDTAGWTPYSYVNVLDSHFQIS
                     ALEARYPPEDFYIELRHLSRHAEPHSPGTCGMDRRQNTYIMDKGFKDYMKESVCSSST
                     CSLNSSENPYATIKDPPILTCKLPESSYVEMKSPVHMGSPYTDVPSLSTSNKNIYEVE
                     PTVSVVQEGRGHNSSYIQNPYDLPRNSHIPGHYDLLPVRQSHAHGPSQDKQ"
ORIGIN      
        1 cagggggtgg gggctgccgt ggcagcagtc gcagcggctc cagcctcctg cttgctcact
       61 cgttctcagt gcccggagcc ggcttcccgg ctcggggcgg ttcgcagctc ccgctcctgc
      121 ctggggacct gaaaccgctc cggctccggg ggataggatc gtgcgactgg ctggcccaag
      181 ccctgggcgc gccgtggaag caggtctcca tagagactgc tgccaggtga ctgtgtacct
      241 ctgaaactcc agcacccaca gctgcttggg cctgatggcg ccgtccacgg tgggcctcct
      301 tgttgtcttc cttctgcaag cggctctcgc tctgaaccct gaggacccca atgtgtgtag
      361 ccactgggag agctacgccg tgaccgtgca ggagtcttat gcacacccct ttgatcagat
      421 ctactacaca cgatgtgcag acatcctcaa ctggttcaag tgtacccggc accggatcag
      481 ctataagacg gcatataggc gcggcctccg gaccatgtac cggcggaggt cccaatgctg
      541 ccctggctac tatgagaatg gagacttctg cattcctctg tgcaccgagg agtgtatgca
      601 tggccgctgc gtctccccgg atacctgcca ctgtgagcct ggatggggag gccctgactg
      661 ttccagtggc tgtgacagcg agcactgggg tccccactgc agcaaccggt gtcagtgtca
      721 gaacggcgcc ttgtgcaacc ctatcaccgg cgcctgcgta tgcgcccccg gcttccgagg
      781 ctggcgctgt gaggaattct gcgcgcccgg tactcacggc aagggctgcc agctgctctg
      841 tcagtgccac cacggcgcta gctgcgaccc gcgcactggc gagtgcctct gcgcaccagg
      901 ctacaccggc gtttactgtg aggagctgtg cccccctggg agccatggag ctcactgtga
      961 gctacgctgc ccctgccaga acggaggcac ctgccaccac atcactggcg agtgtgcctg
     1021 tcctccaggc tggacgggag cagtgtgtgc ccagccctgc ccaccaggga cctttggcca
     1081 gaactgtagt caggactgtc cctgccacca tggaggccag tgtgaccatg tgactggaca
     1141 atgccactgt acagctggat acatggggga caggtgccaa gaagaatgtc cctttggaac
     1201 tttcggtttc cggtgctctc agcgctgtga ctgccacaat ggaggtcaat gttcaccagc
     1261 cacaggtgcc tgtgagtgtg aacctggcta caagggccct agctgccagg aacggctatg
     1321 ccccgagggc ctgcatggcc caggctgcac ctcgccctgt ccctgtgaca ctgagaacac
     1381 tatcagctgc catccagtca ctggagcttg tacctgccag ccaggctggt ctggccacta
     1441 ctgcaatgag tcctgccctg ccggctacta tggcaatggt tgccagctac cctgcacctg
     1501 ccagaacggc gctgactgcc acagcatcac tgggagctgc acttgtgctc caggattcat
     1561 gggagaggtg tgtgccgttc cctgtgcagc agggacctat ggtcccaact gttcatctgt
     1621 atgtagctgt agcaatggcg gcacctgctc ccctgtggat ggctcctgca cctgccgaga
     1681 ggggtggcag ggcctggact gctccctgcc ttgtcccagt gggacctggg gcctgaactg
     1741 caatgagagc tgtgtctgtg ctaatggggc tgcctgcagc ccctttgatg gctcctgtgc
     1801 atgtacccca ggctggctgg gggactcctg cgaactgccc tgcccggatg gcacgtttgg
     1861 gctgaactgc agtgagcact gtgactgcag ccatgctgat ggctgtgacc ctgtcacagg
     1921 ccactgctgc tgcctggcag gatggacagg catccgctgt gatagcacat gtcctccagg
     1981 tcgctggggc cccaactgtt cagtgtcctg cagctgtgaa aacggaggat cctgttcccc
     2041 agtggacggg agctgcgagt gtgcccctgg cttccgagga cccttgtgtc agagaatctg
     2101 cccaccagga ttctacggcc atggctgcgc ccagccttgt cctctctgcg tgcacagcag
     2161 ggggccctgc catcacgtca gtggcatttg tgagtgcctg ccaggattct ctggagcctt
     2221 gtgcaaccaa gtgtgtgctg gagggcactt tgggcaggac tgtgcccagc tctgttcctg
     2281 tgccaacaac gggacctgca gccccattga tggctcctgt caatgcttcc ctggatggac
     2341 tggcaaggac tgctcacagg cctgcccatc tgggttctgg ggctctgcct gcttccacac
     2401 atgcagctgc cacaacgggg cgagctgcag cgccgaggat ggggcctgcc actgcacccc
     2461 tggctggacc ggactcttct gcacgcagcg ttgccctgca gcattttttg ggaaggattg
     2521 tgggcacata tgccagtgtc agaatggagc cagctgtgac cacatcactg ggaaatgcac
     2581 ctgtcgaaca ggcttctctg ggcgccactg tgaacagaga tgtgcccctg gaacctttgg
     2641 atacgggtgt cagcagctat gtgagtgcat gaacaatgcc acttgtgacc atgtcactgg
     2701 tacctgttac tgcagcccgg gattcaaagg aatcaggtgt gaccaagctg ccctcatgat
     2761 ggatgagctg aatccataca ccaagatcag tccagctctg ggagcagagc ggcactcggt
     2821 gggtgctgtc acaggcatca tcctcctgtt gttcctggtt gtggtgttgc tgggcctgtt
     2881 tgcctggcga cggaggcggc agaaagagaa aggccgtgac ctggctcctc gagtctccta
     2941 caccccagcc atgaggatga ccagcacaga ctactctctc tcagatttgt ctcaaagtag
     3001 cagccatgcc cagtgctttt ccaatgccag ctaccacaca ctggcgtgcg gggggcctgc
     3061 caccagccag gcaagcactc tggacaggaa cagccccacc aagctcagta acaagtccct
     3121 tgacagagac acagcaggct ggacccccta cagctatgtg aacgtgttag actcccattt
     3181 ccagatcagt gccctggagg ccaggtaccc gcccgaggac ttctacattg aacttagaca
     3241 cctcagccgc catgctgagc cacactcacc aggcacttgt ggaatggaca gacgtcagaa
     3301 cacatacatt atggacaaag gcttcaaaga ttacatgaaa gaatctgtgt gcagttctag
     3361 tacttgctcc ttgaacagca gtgaaaaccc ttatgccaca attaaggatc cacccatcct
     3421 cacctgcaag cttccagaaa gcagttatgt agaaatgaag tcacctgtgc acatggggtc
     3481 tccgtacaca gatgtgccat ccttgtcaac atctaataaa aatatatatg aagttgagcc
     3541 cacagtcagt gtggtccaag aaggccgagg tcataactcc agctatatcc agaatccata
     3601 cgacctacct aggaacagcc atattcctgg tcactatgac ctcctcccag taagacagag
     3661 ccatgcccat gggccctccc aggacaagca gtaagaggga tacgcttctc tcttagtgtg
     3721 ctctgctgac tattttctga ctctgaaaga agacaatcca agacttgaaa tatcagtaca
     3781 gattgccttg agctgtgtgt tattagttcc ttcactggat tgaaagaagc acttccaaat
     3841 ggggttgggg taactgttca agaaagtctg ttgtgcacaa aggcaaatcc tatcaacctt
     3901 cagccctaaa tgccctggat atgattttta gaacatttaa gatgccactg ttcatcaaca
     3961 tcagctaaaa gatatgtatt taatattctg aaacaacact taagagcatg tagcttaggt
     4021 tctgcaaacc ttcctaggag gaaaaggaca ctggggacgg gaggggcact ttagaggacc
     4081 tgaaatgtat atgtgctgtt gattgctgtt atcctcagca tctgtttcag tatctaaggg
     4141 aattggtatg aggacatgaa ctgttctaat attaatcgcc aagtctgtgt tcatctaggt
     4201 atggcccatc gaattctaat agcaacggta agagttcaaa atatagccga attctttaat
     4261 aaagacagga tcactttctt ttgccctatc actgatatca ggcaaaacag aaaggggaag
     4321 ggggtgggga ggggggaagt aaaatgtttc aaaaaagcag tttcatctac tctagaatga
     4381 tttctatgtc agctgtacca aattttgcca agtcaaagtt caagaatgat gaatggcagt
     4441 cctggcctgg ctgcgctgct ttgattcacc caacacctga gtcaatgtgt gtgcaccaga
     4501 gaaccaagac gctattttaa gaaagtggtc acagggctgg gaatatagct cagttgggag
     4561 aggccttgcc tactgagatc accagcatcg taaaaaacaa aaaaagctta ggcttataag
     4621 aatgaagttt ccccaacaac actatttgga tcactcaagt tacttagagt tccttgactt
     4681 gtttatgagc agttcttcat agatggtgcc aatgtagtgt gggacctaaa ggtgtagaag
     4741 aaattacaca aatgtgggca aggcaagctt atgttgctta gcatatatta tgttttcgat
     4801 gcaactaaat gaagtaaata taaaacaaaa acaaaaagac gtaaaagtcc actgcctgag
     4861 atgggcaaat atgtattcca ctagttggtg ctttcaatct cctattcaga tgagtccata
     4921 acttccactg cacgggtaac agccggaaaa ctgaggcttg gacaattctg aacggctaat
     4981 ccccaagtcc tataggacct cttcacagga attaacaaca gaaagggcaa gctgcaagtt
     5041 aatggccact tttgtgccat cccatgttcg taagaggagt aagtctagag ccagtaaaaa
     5101 ctacttaaaa agggtttacg gaagagggac tagaagactg taaagctaga tactgctaca
     5161 ggaagtgggg atgataacct tagtttgtgt aataatcagc aaaagaaaga aaataaatat
     5221 atgagcaaat ctctttgctc acttcactca aggcctaagc cagtattagc attagaggaa
     5281 cacatacatg aatgctgcat gtgtgcatgg aagcaaatga tcagcaatag taaactttcc
     5341 caaaagcctt attaaaatag aacattagga aattactcgt agacctaagt taatacttct
     5401 catacatatg tataaagaaa tacagttaag aaactcacct cagtatttca gggccacaag
     5461 tgctctatta tctttgcaaa ggaagaatga agaagaatgg caaaatccaa gcagcaagga
     5521 gaaatggtgt ctcaatccca ggctttgtct tcttccctta tcctgcacgc acagtaactg
     5581 ctacctggca aactgcaacc atgcgaattc caagtctcac ttctctcttg ccaactacac
     5641 tctgcacgaa gtatccagca agaggtgaga tggctatagc atcaagtcaa gagaagttag
     5701 caccactctt gttaagtcac ttgccctctc cgggcgcctt tattacccac acatgaaaga
     5761 agagagacag agagtgggag cagagcgcta acaactctcc aagtgtagca ctacatttca
     5821 agtacatagt tcagtcaggc atacagagga gaaggggaac ggcaaagacg tgattaagta
     5881 tggtgacagc agcagccttc acatagctaa gagttagcac taggacattt cgatcatgca
     5941 gagcaactgt taggaacttc taacattcac aaacagattt gcggtcagcc tcaacacgtg
     6001 tgctgtgcat tctatagacg atttggaaag atctgctcac ttatttttca aaatgaaatt
     6061 ttcactccag taaattaata tgtatacaaa tcagacaaag aaaacacagt tactgtacaa
     6121 tagtgtgaga gactatgaaa tggcaatact tttttaaacc acagatttgt aatatatttg
     6181 ttcactgtgc agaggatgta ccttatacaa aataaaatgg attctcaaac taatgttaca
     6241 agaatgtcta ttgttgtgtt gcactgaaac attaatgttt aacattttat gtttaagaca
     6301 gtactaacct acattggtat ggtgacttta aacagctgga agaatgaaaa ttaccacaat
     6361 agatgtttga aaaatgaagc aaaatgttat tttcaaagta acaaacagaa tctccttaac
     6421 tcatgttctg tattttaaaa tcccattcac accagtatta ggtttgtttt tccaaggatg
     6481 tgtactcaaa ggcaactact acagcttatg ttatgctcca gtggcacaaa gtgcaagtgt
     6541 aaaaactatg caatttatat aaaatcccat gaatagcttt taactaatag attttagcat
     6601 atgcatcatt taggacattt taaaccaaat cttgagacac cgctgggttt aaaatataag
     6661 gggggggggg ttgtaggata gtcatcatga tcacaactat aatcccagca cttgggaggc
     6721 tggagcagga ggactgccaa gagttccagg ccagccaggg ctacaatgtg agaccctgtc
     6781 tcaaaacaag caaacaaaca aacagtgaag gccaggcatg tgccacagac tcttgcaatc
     6841 ccattattca ggaggctaag gcaggagagt ttcaagttga agcagcttgg gctacataat
     6901 gagatcaaga gtagcctagg ctaggagatt ttatttcaaa aaacataaaa ggcaggtttg
     6961 ttttgtttaa gaaaatacac acaaagctca gtcagtgaca taacatttgc ctagcatgaa
     7021 ggcttcagtt cccagcatca caaaaactta gaatatagat gccaaaagta gtttactggg
     7081 ctggcacaat gacgatggct caacacccag gacccttaag ggataaggta caggctgtcc
     7141 tctgatttac acacacacac actctcactc tctctctctc tctctctctc tctctctctc
     7201 tctctctctc tcaa
//
