LOCUS       NM_001135813             627 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus mediator complex subunit 31 (Med31), mRNA.
ACCESSION   NM_001135813 XM_001080168 XM_213393
VERSION     NM_001135813.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 627)
  AUTHORS   Poss ZC, Ebmeier CC and Taatjes DJ.
  TITLE     The Mediator complex and transcription regulation
  JOURNAL   Crit Rev Biochem Mol Biol 48 (6), 575-608 (2013)
   PUBMED   24088064
  REMARK    Review article
REFERENCE   2  (bases 1 to 627)
  AUTHORS   Krebs AR, Demmers J, Karmodiya K, Chang NC, Chang AC and Tora L.
  TITLE     ATAC and Mediator coactivators form a stable complex and regulate a
            set of non-coding RNA genes
  JOURNAL   EMBO Rep 11 (7), 541-547 (2010)
   PUBMED   20508642
REFERENCE   3  (bases 1 to 627)
  AUTHORS   Risley MD, Clowes C, Yu M, Mitchell K and Hentges KE.
  TITLE     The Mediator complex protein Med31 is required for embryonic growth
            and cell proliferation during mammalian development
  JOURNAL   Dev Biol 342 (2), 146-156 (2010)
   PUBMED   20347762
REFERENCE   4  (bases 1 to 627)
  AUTHORS   Sato S, Tomomori-Sato C, Banks CA, Sorokina I, Parmely TJ, Kong SE,
            Jin J, Cai Y, Lane WS, Brower CS, Conaway RC and Conaway JW.
  TITLE     Identification of mammalian Mediator subunits with similarities to
            yeast Mediator subunits Srb5, Srb6, Med11, and Rox3
  JOURNAL   J Biol Chem 278 (17), 15123-15127 (2003)
   PUBMED   12584197
REFERENCE   5  (bases 1 to 627)
  AUTHORS   Brower CS, Sato S, Tomomori-Sato C, Kamura T, Pause A, Stearman R,
            Klausner RD, Malik S, Lane WS, Sorokina I, Roeder RG, Conaway JW
            and Conaway RC.
  TITLE     Mammalian mediator subunit mMED8 is an Elongin BC-interacting
            protein that can assemble with Cul2 and Rbx1 to reconstitute a
            ubiquitin ligase
  JOURNAL   Proc Natl Acad Sci U S A 99 (16), 10353-10358 (2002)
   PUBMED   12149480
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 16, 2008 this sequence version replaced
            XM_001080168.1, XM_213393.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ211088.1, CB569479.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676811 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..627
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..627
                     /gene="Med31"
                     /gene_synonym="RGD1309457"
                     /note="mediator complex subunit 31"
                     /db_xref="GeneID:287475"
                     /db_xref="RGD:1309457"
     exon            1..84
                     /gene="Med31"
                     /gene_synonym="RGD1309457"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..452
                     /gene="Med31"
                     /gene_synonym="RGD1309457"
                     /note="mediator of RNA polymerase II transcription,
                     subunit 31 homolog"
                     /codon_start=1
                     /product="mediator of RNA polymerase II transcription
                     subunit 31"
                     /protein_id="NP_001129285.1"
                     /db_xref="GeneID:287475"
                     /db_xref="RGD:1309457"
                     /translation="MAAAVAMETDDAGNRLRFQLELEFVQCLANPNYLNFLAQRGYFK
                     DKAFVNYLKYLLYWKEPEYAKYLKYPQCLHMLELLQYEHFRKELVNAQCAKFIDEQQI
                     LHWQHYSRKRMRLQQALAEQQQQNTTAGK"
     exon            85..162
                     /gene="Med31"
                     /gene_synonym="RGD1309457"
                     /inference="alignment:Splign:2.1.0"
     exon            163..259
                     /gene="Med31"
                     /gene_synonym="RGD1309457"
                     /inference="alignment:Splign:2.1.0"
     exon            260..627
                     /gene="Med31"
                     /gene_synonym="RGD1309457"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 accaatccgg gctgcggttg ggtcgggttg gtagtgtttg cgcctttctg cttgctatgg
       61 ccgcggccgt cgctatggag acagatgatg ctggaaatcg acttcggttt cagttggagt
      121 tggaatttgt gcaatgttta gccaacccaa attaccttaa ttttctcgcc caaagaggtt
      181 acttcaaaga caaagctttt gttaattatc ttaagtactt gctttactgg aaagaaccag
      241 aatatgccaa atatctaaag taccctcagt gtttgcatat gttagaactg ctccaatatg
      301 aacactttcg aaaggagctg gtgaatgctc agtgtgcgaa gttcattgac gaacagcaga
      361 ttctgcactg gcagcactat tcgaggaagc ggatgcgtct tcagcaagcc ctagcagagc
      421 agcagcagca gaataccaca gcaggaaaat gaagagctgg caacagcagg ctctaggaca
      481 tgtatataat gcactgctat tgtacagtac agagagaaag actgctgccc cctttattgt
      541 agtactcaga actattagtg ttatttttgg ttggcaaaac tttttgttaa tagttgattt
      601 ctattaaacc aggattgctc tactttg
//
