LOCUS       NM_001107300            3618 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus mediator complex subunit 26 (Med26), mRNA.
ACCESSION   NM_001107300 XM_001067877 XM_224707
VERSION     NM_001107300.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3618)
  AUTHORS   Poss ZC, Ebmeier CC and Taatjes DJ.
  TITLE     The Mediator complex and transcription regulation
  JOURNAL   Crit Rev Biochem Mol Biol 48 (6), 575-608 (2013)
   PUBMED   24088064
  REMARK    Review article
REFERENCE   2  (bases 1 to 3618)
  AUTHORS   Krebs AR, Demmers J, Karmodiya K, Chang NC, Chang AC and Tora L.
  TITLE     ATAC and Mediator coactivators form a stable complex and regulate a
            set of non-coding RNA genes
  JOURNAL   EMBO Rep 11 (7), 541-547 (2010)
   PUBMED   20508642
REFERENCE   3  (bases 1 to 3618)
  AUTHORS   Zhang X, Krutchinsky A, Fukuda A, Chen W, Yamamura S, Chait BT and
            Roeder RG.
  TITLE     MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation
            enriched in RNA polymerase II and is required for ER-mediated
            transcription
  JOURNAL   Mol Cell 19 (1), 89-100 (2005)
   PUBMED   15989967
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000275.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001107300.4.
            
            On Feb 10, 2021 this sequence version replaced NM_001107300.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB783501.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-340               JACYVU010000275.1  649055-649394
            341-415             JACYVU010000275.1  695164-695238
            416-3618            JACYVU010000275.1  695674-698876
FEATURES             Location/Qualifiers
     source          1..3618
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p14"
     gene            1..3618
                     /gene="Med26"
                     /gene_synonym="Slc35e1"
                     /note="mediator complex subunit 26"
                     /db_xref="GeneID:306328"
                     /db_xref="RGD:1309524"
     exon            1..340
                     /gene="Med26"
                     /gene_synonym="Slc35e1"
                     /inference="alignment:Splign:2.1.0"
     CDS             269..2035
                     /gene="Med26"
                     /gene_synonym="Slc35e1"
                     /note="solute carrier family 35, member E1"
                     /codon_start=1
                     /product="mediator of RNA polymerase II transcription
                     subunit 26"
                     /protein_id="NP_001100770.2"
                     /db_xref="GeneID:306328"
                     /db_xref="RGD:1309524"
                     /translation="MTAAPASPQQMRDRLLQAIDSQSNIRNMVAVLEVISSLERYPIT
                     KEALEETRLGKLINDVRKKTKNEELAKRAKRLLRSWQKLIEPVHQNEVALRALAGAAG
                     SANGGAHNCRPELGVAGAPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPG
                     PPHKVSKGSPDPLVPNASPLPTNGISGSPESLPSPLDGSGHLGPDGSRLELSENEKHS
                     TKIPVNAVRPRPSSPGLGKPPVPCLQTKAAQLQPLDRADEPPGPPYPRGSPRCSISPR
                     NSRHEGSFARHRSSYIPKGPVSSPSPRPQPLDTTQVPSPLPLAQPPTPPVRRLDLLPN
                     AESPVHWPEQPEGHPRLTGPACRAGLSPDSSKADSDAASSGGSDSKKKKRYRPRDYTV
                     NLDGQVAEAGVKPVRLKERKLTFDPMTRQIRPLTQKEPVRADSPVPTEQLPRTELEQQ
                     EAKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMAEYLKQEES
                     SRQGARQPHVLLPLPTPTDLPGLTREVTQDDLDRIQAQQWPGVNGCEDTQGNWYDWTQ
                     CISLDPHGDDGRLNILPYVCLD"
     exon            341..415
                     /gene="Med26"
                     /gene_synonym="Slc35e1"
                     /inference="alignment:Splign:2.1.0"
     exon            416..3618
                     /gene="Med26"
                     /gene_synonym="Slc35e1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggcggcgg cggcggtagt ggcggaggct tctccgtcgg ctcctcctcc tccttgctcg
       61 gcggtggcgg cggcggtccg gggcctgagc tccggtcccc tccgctttcc tccgtcctcc
      121 gccatctccc cgagcgcctc gacctcctct ggcgccgcgg ggaacatgcg gctccgttcc
      181 cggaggccgg cgagtgactg acctgcgtcc cccctcctca gcctgcccgc ccgccggccc
      241 ggccgctccc ccccgcttcg cccaggcaat gacagcggct ccggcgtctc cgcagcagat
      301 gagggaccgg ctgctacagg ccatcgactc ccagagcaac atccggaaca tggtggcagt
      361 attggaagtg atctccagtc tggagagata tcctatcacc aaagaggcac tggaggagac
      421 acgactaggg aaactcatca acgacgtccg taagaaaacc aagaatgagg agctggccaa
      481 gcgggccaag aggctgctgc ggagctggca gaagctcatc gagcccgtac accagaatga
      541 agtggcacta cgggcactgg cgggggctgc aggctctgcc aatgggggtg cacacaactg
      601 ccggccagag ctgggagtgg ctggtgcacc caagagcatc catgacctga agaatcgcaa
      661 cgacatccaa aggctccctg ggcagcggct agataggctg ggcagccgta agcgcagggg
      721 ggaccagcgt gacctgggtc acccagggcc accccacaaa gtttccaaag gcagtcctga
      781 ccccctggtc cccaatgcat cccctctccc caccaatggg atcagcggga gcccagagag
      841 cttacccagc cccctggatg ggagtgggca cttgggccct gatggcagcc gtctggagct
      901 cagcgagaac gagaagcaca gcaccaagat ccccgtgaac gccgtgcggc cacgtcccag
      961 ctcccctggt ttgggcaagc ccccagttcc ctgcctgcag accaaggctg cacagttgca
     1021 gccattggac agggcggatg agcccccagg ccctccctat cccagggggt cccctcgctg
     1081 ctccatcagc ccccggaact cacggcacga aggctccttt gcccggcatc ggagctcgta
     1141 tatacccaag ggcccagtgt ccagcccttc cccccggccc cagccattgg acaccacaca
     1201 ggtaccatcc ccactcccgc tggcccagcc gcccacgccc cctgtgcgga ggctggacct
     1261 gctgcctaat gctgagagcc ctgtgcactg gccagagcag cccgagggcc acccacggct
     1321 aacggggcca gcctgcaggg ctggattgtc cccagattcc tccaaggcgg acagtgatgc
     1381 tgcctcttcg ggtggctcgg acagcaaaaa gaaaaaaagg taccgacctc gagactacac
     1441 agtgaacttg gatgggcagg tggctgaggc aggcgtcaag cccgtgaggt taaaagagcg
     1501 gaagctcacc tttgacccca tgacaagaca gatcaggcct ctgacccaga aagagccagt
     1561 tcgggctgac agccccgtac ccacagaaca gctgcctagg acagagctgg agcagcagga
     1621 ggccaaggcc agcctccaga gcccttttga gcagacgaac tggaaggagc tgtcgcgcaa
     1681 tgagatcata cagtcctacc tgagccgcca gagcagcctg ctttcatcct caggcgcaca
     1741 gacccctggt gcacaccact ttatggctga gtacctgaag caggaggaga gcagtcggca
     1801 aggggcccgg cagccccatg tgctgctgcc actgcccacg ccaactgacc taccagggct
     1861 cacgcgcgag gtcacacagg atgatctgga cagaatccag gcccagcagt ggccgggggt
     1921 taacgggtgt gaagacacac agggtaattg gtatgactgg acacaatgta tatcgctcga
     1981 ccctcatggt gacgatgggc gcttgaacat tctgccttat gtctgcttgg actgagcacc
     2041 tgacctggcc accatgtgca ttcccacctc gcagggatta ggctggccag ctgggaagac
     2101 gagcatgagg ctcgctctcc accctccttt tttgaaatgc tgctaccagt ttactaacgt
     2161 tgcaaaggaa gggccgctcg ggggaggggc agatggctga gggagtctag aactctatag
     2221 taagtcagct atgaagcgtt attccccatc ccagaagagg tgcagagcca ttcttaagca
     2281 ccgaaggagg gacctcagtg gcaggcaggc acaggaaccc tgtgggagag gttaccttaa
     2341 cagcaacaga cgcacatctc atctctgcat ctcttgctct ttggccatgg tgtctctgag
     2401 gcacgggcca ctctggagcc agtgggttct tttttttttt tttttttttt tttttttttt
     2461 tttgtttttt ttgtccccct cgtgttgtgt gctggaagct tctctgctgt ggtgaaccct
     2521 ggcattgggt gggtgggcca gcctcaccca cactgcacag tcgtccaccc atttgtatat
     2581 ggtttcagtt cagtcccagt tcttaaagaa atgctgcaga aacttaagtt ttgtcgttta
     2641 tttcatcctt tttcccctac caccagccaa atgacttttc cttcccttct ttccttttct
     2701 gcacaactct aggaaatgcc atctttctag agtctgtata accctacaaa gttcccgagg
     2761 gtgctactgg tgtgagttgc cctgctgggc taggggagag ccgtctgttt gctggaaaca
     2821 ctcataacca ttcctttaga ttcgtttgcc ttatggttgt cataaactcg atttgcaaaa
     2881 acaaggagcc ttagtgaatg tacagtacct agacttctgt gttcacgcag aagggagcaa
     2941 ctttgctatt tggtccagta agtggacaac ttgtgatata aatgtggaaa taaaaacatt
     3001 tgcacaaacc agttttggaa tcatttctca tttgcacatg aacagctaaa tctagccttt
     3061 actagattct actatgggga agtcactgga gcccacaacc atacccactg ggccagacta
     3121 agtgacattc ctttagcttt aattttgtag ctgcaggcca gggtctgtct ctacttgctt
     3181 ttcattgatt catggtcaac cacatcccct gggtcaccca cctagaagag cccctgctgc
     3241 aggcagtgta gctcctctta gtgacatggt gtgcaccttc cctgcccacc agtactttgc
     3301 tgacattgca tgacccagat gtacaggact actttctggc ctcggctctg ggctagcagc
     3361 tgcaggcagg ctcgaggctg cctccatacc tgacaggtgc ccactaagat gtcacctcgt
     3421 tataaagtaa tgatctagct ttctcttctc cctcagttaa taagccaaga ttggctttct
     3481 agtatttttt tcactcttac tatccatatc tgcttaattt cacagatgag ttaagttact
     3541 cataaaacag ctgcttcatg gtttgagcct tagaacatac tttctggtct ggtcggtacc
     3601 acagccagcc cagaatca
//
