LOCUS       NM_001399586             729 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus mediator complex subunit 11 (Med11), mRNA.
ACCESSION   NM_001399586 XM_006246660
VERSION     NM_001399586.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 729)
  AUTHORS   Poss,Z.C., Ebmeier,C.C. and Taatjes,D.J.
  TITLE     The Mediator complex and transcription regulation
  JOURNAL   Crit Rev Biochem Mol Biol 48 (6), 575-608 (2013)
   PUBMED   24088064
  REMARK    Review article
REFERENCE   2  (bases 1 to 729)
  AUTHORS   Tomomori-Sato,C., Sato,S., Parmely,T.J., Banks,C.A., Sorokina,I.,
            Florens,L., Zybailov,B., Washburn,M.P., Brower,C.S., Conaway,R.C.
            and Conaway,J.W.
  TITLE     A mammalian mediator subunit that shares properties with
            Saccharomyces cerevisiae mediator subunit Cse2
  JOURNAL   J Biol Chem 279 (7), 5846-5851 (2004)
   PUBMED   14638676
REFERENCE   3  (bases 1 to 729)
  AUTHORS   Sato,S., Tomomori-Sato,C., Banks,C.A., Sorokina,I., Parmely,T.J.,
            Kong,S.E., Jin,J., Cai,Y., Lane,W.S., Brower,C.S., Conaway,R.C. and
            Conaway,J.W.
  TITLE     Identification of mammalian Mediator subunits with similarities to
            yeast Mediator subunits Srb5, Srb6, Med11, and Rox3
  JOURNAL   J Biol Chem 278 (17), 15123-15127 (2003)
   PUBMED   12584197
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Jan 12, 2022 this sequence version replaced XM_006246660.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CK839152.1, FQ221563.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-146               JAXUCZ010000010.1  55662956-55663101
            147-277             JAXUCZ010000010.1  55663248-55663378
            278-729             JAXUCZ010000010.1  55664123-55664574
FEATURES             Location/Qualifiers
     source          1..729
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..729
                     /gene="Med11"
                     /gene_synonym="RGD1563202"
                     /note="mediator complex subunit 11"
                     /db_xref="GeneID:287456"
                     /db_xref="RGD:1563202"
     exon            1..146
                     /gene="Med11"
                     /gene_synonym="RGD1563202"
                     /inference="alignment:Splign:2.1.0"
     CDS             62..415
                     /gene="Med11"
                     /gene_synonym="RGD1563202"
                     /note="mediator of RNA polymerase II transcription,
                     subunit 11 homolog"
                     /codon_start=1
                     /product="mediator of RNA polymerase II transcription
                     subunit 11"
                     /protein_id="NP_001386515.1"
                     /db_xref="GeneID:287456"
                     /db_xref="RGD:1563202"
                     /translation="MATYSLANERLRALEDIEREIGAILQNAGTAILELSKEKTNERL
                     LDRQAAAFTASVQHVEAELSAQIRYLTQVATGQPHEGSSYSSRKDCQMALKRVDYARL
                     KISDVARTCEQMLEN"
     exon            147..277
                     /gene="Med11"
                     /gene_synonym="RGD1563202"
                     /inference="alignment:Splign:2.1.0"
     exon            278..729
                     /gene="Med11"
                     /gene_synonym="RGD1563202"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atttccgggc cttggcgccg cacctcgcaa aagacagcct gcggggcttt ccactggaac
       61 gatggctacc tacagcctgg cgaacgagcg gctgcgcgcc ctggaggaca tcgagcgcga
      121 aatcggcgcc atcctccaga acgcaggaac agcaatcctg gaactgtcca aggaaaaaac
      181 gaacgagcgt ctcctagacc ggcaggcggc agccttcacc gcttctgtgc agcacgtgga
      241 ggcagagctg tccgctcaga tccgctacct cacccaggtg gccacagggc agccgcatga
      301 gggctccagc tattcttcca ggaaggactg tcaaatggct ctcaagcgag tagattacgc
      361 ccgcctcaag atcagtgatg tggcaagaac ctgtgaacag atgctggaga actaagtcag
      421 gatgatccag agtgtgaact gcaccttggg acagaaccca gagaccggta ggatggggaa
      481 cagagtaata tctacatgcc ctactggttc agggcagatg aggaccacga gtccgaaagc
      541 agaactggag actccaaagc ccaagtgtac acacagattt cttctggctc ctccagcaag
      601 acagccctgt tttccactgt gcaagctgag acaggagtca gaggtcaact tccaacccac
      661 ttcctcgtgt gcacccttcc ctggcatttc agaagacttg gcccaataaa aataaatgta
      721 ttcttagta
//
