LOCUS       NM_001414944            8361 bp    mRNA    linear   ROD 14-FEB-2025
DEFINITION  Rattus norvegicus MAM domain containing
            glycosylphosphatidylinositol anchor 1 (Mdga1), mRNA.
ACCESSION   NM_001414944 XM_006256207
VERSION     NM_001414944.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 8361)
  AUTHORS   Li,H.L., Guo,R.J., Ai,Z.R., Han,S., Guan,Y., Li,J.F. and Wang,Y.
  TITLE     Upregulation of Spinal MDGA1 in Rats After Nerve Injury Alters
            Interactions Between Neuroligin-2 and Postsynaptic Scaffolding
            Proteins and Increases GluR1 Subunit Surface Delivery in the Spinal
            Cord Dorsal Horn
  JOURNAL   Neurochem Res 49 (2), 507-518 (2024)
   PUBMED   37955815
  REMARK    GeneRIF: Upregulation of Spinal MDGA1 in Rats After Nerve Injury
            Alters Interactions Between Neuroligin-2 and Postsynaptic
            Scaffolding Proteins and Increases GluR1 Subunit Surface Delivery
            in the Spinal Cord Dorsal Horn.
REFERENCE   2  (bases 1 to 8361)
  AUTHORS   Toledo,A., Letellier,M., Bimbi,G., Tessier,B., Daburon,S.,
            Favereaux,A., Chamma,I., Vennekens,K., Vanderlinden,J., Sainlos,M.,
            de Wit,J., Choquet,D. and Thoumine,O.
  TITLE     MDGAs are fast-diffusing molecules that delay excitatory synapse
            development by altering neuroligin behavior
  JOURNAL   Elife 11, e75233 (2022)
   PUBMED   35532105
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8361)
  AUTHORS   Gangwar,S.P., Zhong,X., Seshadrinathan,S., Chen,H., Machius,M. and
            Rudenko,G.
  TITLE     Molecular Mechanism of MDGA1: Regulation of Neuroligin 2:Neurexin
            Trans-synaptic Bridges
  JOURNAL   Neuron 94 (6), 1132-1141 (2017)
   PUBMED   28641112
REFERENCE   4  (bases 1 to 8361)
  AUTHORS   Pettem,K.L., Yokomaku,D., Takahashi,H., Ge,Y. and Craig,A.M.
  TITLE     Interaction between autism-linked MDGAs and neuroligins suppresses
            inhibitory synapse development
  JOURNAL   J Cell Biol 200 (3), 321-336 (2013)
   PUBMED   23358245
  REMARK    GeneRIF: MDGA binding and suppression of synaptogenic activity was
            selective for neuroligin-2 and not neuroligin-1 excitatory synapse
            organizer.
REFERENCE   5  (bases 1 to 8361)
  AUTHORS   Lee,K., Kim,Y., Lee,S.J., Qiang,Y., Lee,D., Lee,H.W., Kim,H.,
            Je,H.S., Sudhof,T.C. and Ko,J.
  TITLE     MDGAs interact selectively with neuroligin-2 but not other
            neuroligins to regulate inhibitory synapse development
  JOURNAL   Proc Natl Acad Sci U S A 110 (1), 336-341 (2013)
   PUBMED   23248271
  REMARK    GeneRIF: MDGAs interact selectively with neuroligin-2 but not other
            neuroligins to regulate inhibitory synapse development.
            Erratum:[Proc Natl Acad Sci U S A. 2024 Jun 25;121(26):e2410442121.
            doi: 10.1073/pnas.2410442121.. PMID: 38885391]
REFERENCE   6  (bases 1 to 8361)
  AUTHORS   Ishikawa,T., Gotoh,N., Murayama,C., Abe,T., Iwashita,M.,
            Matsuzaki,F., Suzuki,T. and Yamamoto,T.
  TITLE     IgSF molecule MDGA1 is involved in radial migration and positioning
            of a subset of cortical upper-layer neurons
  JOURNAL   Dev Dyn 240 (1), 96-107 (2011)
   PUBMED   21104742
REFERENCE   7  (bases 1 to 8361)
  AUTHORS   Tissir,F., Qu,Y., Montcouquiol,M., Zhou,L., Komatsu,K., Shi,D.,
            Fujimori,T., Labeau,J., Tyteca,D., Courtoy,P., Poumay,Y., Uemura,T.
            and Goffinet,A.M.
  TITLE     Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis,
            leading to fatal hydrocephalus
  JOURNAL   Nat Neurosci 13 (6), 700-707 (2010)
   PUBMED   20473291
REFERENCE   8  (bases 1 to 8361)
  AUTHORS   Takeuchi,A. and O'Leary,D.D.
  TITLE     Radial migration of superficial layer cortical neurons controlled
            by novel Ig cell adhesion molecule MDGA1
  JOURNAL   J Neurosci 26 (17), 4460-4464 (2006)
   PUBMED   16641224
REFERENCE   9  (bases 1 to 8361)
  AUTHORS   Diaz-Lopez,A., Rivas,C., Iniesta,P., Moran,A., Garcia-Aranda,C.,
            Megias,D., Sanchez-Pernaute,A., Torres,A., Diaz-Rubio,E., Benito,M.
            and De Juan,C.
  TITLE     Characterization of MDGA1, a novel human
            glycosylphosphatidylinositol-anchored protein localized in lipid
            rafts
  JOURNAL   Exp Cell Res 307 (1), 91-99 (2005)
   PUBMED   15922729
REFERENCE   10 (bases 1 to 8361)
  AUTHORS   Litwack,E.D., Babey,R., Buser,R., Gesemann,M. and O'Leary,D.D.
  TITLE     Identification and characterization of two novel brain-derived
            immunoglobulin superfamily members with a unique structural
            organization
  JOURNAL   Mol Cell Neurosci 25 (2), 263-274 (2004)
   PUBMED   15019943
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Dec 15, 2022 this sequence version replaced XM_006256207.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1264              JAXUCZ010000020.1  7964571-7965834     c
            1265-1404           JAXUCZ010000020.1  7933351-7933490     c
            1405-1579           JAXUCZ010000020.1  7927643-7927817     c
            1580-1776           JAXUCZ010000020.1  7925395-7925591     c
            1777-1909           JAXUCZ010000020.1  7924622-7924754     c
            1910-2179           JAXUCZ010000020.1  7924152-7924421     c
            2180-2509           JAXUCZ010000020.1  7921398-7921727     c
            2510-2806           JAXUCZ010000020.1  7917994-7918290     c
            2807-3094           JAXUCZ010000020.1  7917317-7917604     c
            3095-3246           JAXUCZ010000020.1  7915645-7915796     c
            3247-3424           JAXUCZ010000020.1  7914676-7914853     c
            3425-3448           JAXUCZ010000020.1  7914406-7914429     c
            3449-3601           JAXUCZ010000020.1  7913337-7913489     c
            3602-3736           JAXUCZ010000020.1  7912815-7912949     c
            3737-3867           JAXUCZ010000020.1  7907846-7907976     c
            3868-3976           JAXUCZ010000020.1  7907534-7907642     c
            3977-8361           JAXUCZ010000020.1  7901856-7906240     c
FEATURES             Location/Qualifiers
     source          1..8361
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..8361
                     /gene="Mdga1"
                     /note="MAM domain containing glycosylphosphatidylinositol
                     anchor 1"
                     /db_xref="GeneID:309659"
                     /db_xref="RGD:1307031"
     exon            1..1264
                     /gene="Mdga1"
                     /inference="alignment:Splign:2.1.0"
     CDS             1198..4068
                     /gene="Mdga1"
                     /note="MAM domain-containing glycosylphosphatidylinositol
                     anchor protein 1; ig6M"
                     /codon_start=1
                     /product="MAM domain-containing
                     glycosylphosphatidylinositol anchor protein 1 precursor"
                     /protein_id="NP_001401873.1"
                     /db_xref="GeneID:309659"
                     /db_xref="RGD:1307031"
                     /translation="MEVTCLLLLALIPFHCRGQGVYAPAQAQIVHAGQACVVKEDNIS
                     ERVYTIRESDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQ
                     GGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTVSDVRGNFYQEKTVFLRCTVS
                     SNPPARFIWKRGSDTLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSV
                     RNVCGIPDKSITFQLTNTTAPPTLKLSVNETLVVNPGENVTVQCLLTGGDPLPQLHWS
                     HGPGPLPLGALAQGGTLSIPSVQARDSGYYNCTATNNVGNPAKKTVNLLVRSLKNATF
                     QITPDMIKESENIQLGQDLKLSCHVDAVPQEKVNYQWFKNGKPARTSKRLLVTRNDPE
                     LPAVTSSLELIDLHFSDYGTYLCVASFPGSPVPDLSVEVNISSETVPPTISVPKGRAV
                     VTVREGSPAELQCEVRGKPRPPVLWSRVDKEAALLPSGLALEETPDGKLRVERVSREM
                     SGTYRCQTARYNGFNVRAREAQVQLTVHFPPEVEPSSQDVRQALGRPVLLRCSLLRGS
                     PQRIASAVWRFKGQLLPPPPVLPAAAAEGPDHAELRLDALTRDSSGNYECSVSNDVGS
                     ATCLFQVSAKAYSPEFYFDTPNPTRSHKLSKNYSYVLQWTQREPDAVDPVLNYRLSIR
                     QLNQHNAMVKAIPVRRVEKGQLLEYTLTDLRVPHSYEIHLTPYTTFGAGDMASRVIHY
                     TEPINSPSLSDNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDISG
                     TPEGYYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSR
                     NKGTLDTHAWSLSGNKGNVWQQAHVPINPSGPFQIIFEGVRGSGYLGDIAIDDVTLKK
                     GECPRRQMDPNKVVVMPGSGAPRLSSLQLWGSMTIFLLALQR"
     exon            1265..1404
                     /gene="Mdga1"
                     /inference="alignment:Splign:2.1.0"
     exon            1405..1579
                     /gene="Mdga1"
                     /inference="alignment:Splign:2.1.0"
     exon            1580..1776
                     /gene="Mdga1"
                     /inference="alignment:Splign:2.1.0"
     exon            1777..1909
                     /gene="Mdga1"
                     /inference="alignment:Splign:2.1.0"
     exon            1910..2179
                     /gene="Mdga1"
                     /inference="alignment:Splign:2.1.0"
     exon            2180..2509
                     /gene="Mdga1"
                     /inference="alignment:Splign:2.1.0"
     exon            2510..2806
                     /gene="Mdga1"
                     /inference="alignment:Splign:2.1.0"
     exon            2807..3094
                     /gene="Mdga1"
                     /inference="alignment:Splign:2.1.0"
     exon            3095..3246
                     /gene="Mdga1"
                     /inference="alignment:Splign:2.1.0"
     exon            3247..3424
                     /gene="Mdga1"
                     /inference="alignment:Splign:2.1.0"
     exon            3425..3448
                     /gene="Mdga1"
                     /inference="alignment:Splign:2.1.0"
     exon            3449..3601
                     /gene="Mdga1"
                     /inference="alignment:Splign:2.1.0"
     exon            3602..3736
                     /gene="Mdga1"
                     /inference="alignment:Splign:2.1.0"
     exon            3737..3867
                     /gene="Mdga1"
                     /inference="alignment:Splign:2.1.0"
     exon            3868..3976
                     /gene="Mdga1"
                     /inference="alignment:Splign:2.1.0"
     exon            3977..8361
                     /gene="Mdga1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagagcgag agaccgatcg cggagatggg aggagggaga gagggaggag ggagagcggg
       61 aggcggggtg gtggtggtgg ggaggtggag gaagcgcgga atgaaaagct cggagggacc
      121 agaaagcagc acagcgaagc ccaagttgcc gagcgagcgg agcgctcccg cggccccgga
      181 gcccgagtgg ccgccgtgcc cgggagcctg gcccggcccc gcccgctggg gccccctcgg
      241 ccccaggccg ccgggagggg ggcggggacg cccaacttgg ggcgcggcgc agccccgctc
      301 tcccgagatc gcggagcccg ggaatgccac ggcggcggcc agacggcggg agaggagcgg
      361 ggagagagga ggcggcgggc ggctcctgag cccaggcctc cgcaagagcg cgaattattt
      421 tcaaaggact caaactttcc tctttccctt gctggctgtg gtgcctcttg ctttggaaac
      481 gttctccgga ttcccgcggg ggcgccggga cgcgatcacc tcccccggat tcctcggcgg
      541 cggctcggct aacttcgcgg actcggagac gcggagcgct cgccccgcgg cggaagccag
      601 tcctcgctgc tccggcgctt cagaggaccg ggacccgggc gccctcgcct ccgggaaggg
      661 cgctcagccc cgctcccctg ggtcgggctg cggagccctc cacacctact gcaggactgg
      721 agccagcgga ttaaccatag cagagacccg gcctcctggc ctggctccgc cgaggggcgt
      781 cccctgggcg gggaaaccac aagttttgcc aggcatcggt ggcctgttgg atccgcgcgc
      841 ggccgccaca gcagagaggt ccctcgcgct cagcacgctg ggcggacagc cctgggaacc
      901 caggactgct cggtggccga gctttctggg ccagggagct ggttgctgcg cccggtgcgc
      961 agaggcatca aggtctgggc cagcgccccc tgcgtctcca cccgggcagc cgccctatgg
     1021 aaagagaacg gagccgagtc gcggtttgct tagactccta gtctcggtcg ccgccctctc
     1081 cttcgcgtct cagggaaaag gagggaacgc agagggcatc gcggtgcccc ggcggatgcg
     1141 ccccccgccg cctctcaggc tgcgccgcct cgtggggatg aagcactggc cgtgaagatg
     1201 gaggtgacct gccttctact tctggcgctg atccccttcc actgtcgggg acaaggagtc
     1261 tacgctccag cccaggccca gatcgtgcat gcagggcagg cctgtgtggt gaaggaggat
     1321 aatatcagcg agcgggtcta taccatccgg gagagcgaca ccctggtgct gcagtgcctg
     1381 gttactgggc accctcggcc ccaggtgcgg tggaccaaaa ctgcgggcag cgcatccgac
     1441 aagttccagg agacttcggt gttcaatgaa actctgcgga tcgagcgcat cgcccgcacg
     1501 cagggaggcc gctactactg caaggcggag aacggagtgg gcgtgccggc catcaagtcc
     1561 atccgcgtgg acgtgcagta cttggatgaa cctgtgttga cggtgcatca gacggtgagc
     1621 gacgtccgag gcaacttcta ccaggagaag accgtgtttc tacgctgtac cgtcagttcc
     1681 aacccgcccg cccgctttat ctggaagcgg ggctccgaca ccctgtccca cagccaggac
     1741 aatggggttg acatctacga gcctctctat actcaggggg agacgaaggt cttgaagctg
     1801 aagaacctgc ggccccaaga ctatgccagc tacacctgcc aggtgtctgt gcgtaacgtg
     1861 tgcggcatcc ctgacaagtc tatcaccttc cagctcacca acaccacggc acctccaact
     1921 ttgaagctgt ctgtgaacga aactctggtg gtgaaccctg gggagaatgt gacagtgcag
     1981 tgcctgctga cgggcggcga tcccctccca cagctgcact ggtcccacgg acctggccca
     2041 ctgcctctgg gtgcgctggc tcagggtggt acccttagca ttccttcagt gcaggcccgg
     2101 gattccggtt actacaactg cacagccacc aacaatgtag gcaacccagc caagaagacg
     2161 gtcaacctgc tggtgcgatc cttgaagaat gccaccttcc agatcacccc tgacatgatc
     2221 aaagagagcg agaacattca acttggtcag gatctgaagc tctcatgcca tgtggacgcg
     2281 gtgccccagg agaaggtgaa ctaccagtgg tttaaaaacg gcaagccggc acgcacgtcc
     2341 aagcggctgc tggtgacccg aaatgaccct gagctgcccg ctgtcaccag cagcctggag
     2401 ctcattgacc tgcacttcag cgactacggc acttatctgt gcgtggcttc cttcccgggg
     2461 tcacctgtgc ctgacctcag cgtagaggtc aacatctcct ccgagacagt accgcccacc
     2521 atcagtgtgc ccaagggccg agcagtggtg acagttcggg agggctctcc tgctgagctt
     2581 cagtgcgaag tgcgcggcaa accccggcct ccagtgctgt ggtcccgcgt ggacaaggag
     2641 gccgcccttc tgccctcggg gctggctctg gaagagactc cggatgggaa gctccgagtg
     2701 gagcgcgtga gccgcgaaat gagcggcacc tatcgctgcc agacggctcg ctataatggc
     2761 ttcaacgtac gagcccggga ggctcaggtg cagctgacag tgcacttccc tccagaggtg
     2821 gagcccagtt cccaagacgt gcgccaggcg ctgggccgcc ctgtgctcct gcgctgctcg
     2881 ctcctgcgtg gcagtcccca gcgcatcgcc tcggccgtgt ggcgcttcaa aggacagctg
     2941 ctgcccccgc cgcctgttct ccccgccgct gccgccgagg gcccggacca cgccgagctg
     3001 cgcctggacg ccctgacccg tgacagcagc ggtaactacg aatgcagcgt ctccaacgac
     3061 gtgggctcag ccacctgcct cttccaggtc tccgccaaag cctacagccc ggagttttac
     3121 ttcgacaccc ccaaccccac ccgcagccac aagctgtcca agaactactc ctatgtgcta
     3181 cagtggacgc agagggagcc ggacgccgtg gaccctgtgc tcaactacag actcagcatc
     3241 cgccagttga accagcacaa tgccatggtc aaggccatcc ctgttcggcg tgtggagaag
     3301 gggcagctgc tggagtacac cttgactgac ctccgtgtgc cccacagcta tgagatccac
     3361 ctcacaccct acaccacctt tggggctgga gacatggctt cccgagtcat ccactacaca
     3421 gagcctatca actcgcccag cctgtcagac aatacctgtc actttgagga tgagaaaatc
     3481 tgcggataca cccaggatct gacagacaac ttcgactgga cacggcagaa tgcgcttacc
     3541 cagaatccca agcgctctcc caatactggg ccacctacgg acatcagtgg cacccccgaa
     3601 ggctactaca tgttcattga gacatcaaga ccccgggagc tgggggaccg ggcaaggctg
     3661 gtgagtcccc tgtacaacgc cagcgccaag ttctactgcg tctctttctt ctaccacatg
     3721 tacggcaaac acatcggctc cctcaacctt ctggtgaggt ccaggaacaa aggcactcta
     3781 gacacgcatg cctggtccct cagcggtaat aaaggtaacg tgtggcaaca ggcccacgtg
     3841 cccatcaacc ccagcggacc cttccagatt atttttgagg gggttcgagg ctcgggctac
     3901 ctgggggata ttgccataga tgatgtcaca ctgaagaagg gagagtgtcc ccggaggcag
     3961 atggatccca acaaagtggt ggtgatgcca ggcagtggag ccccccgcct gtccagcctg
     4021 cagctttggg gatccatgac catcttcctc ttggcgttgc agagatgatg agagctgtgt
     4081 ggcccccacc ccaccctgcc cccggcacac caaagtgtcc acatcgtacc aaagactgac
     4141 ccctgccagc cggggtgccc aggggcgggg ccggcccacc agggaggggg ccttcattgg
     4201 ctgcaaggat gagtggagaa cgtggacaga ggccaggcca gactctggtg gttgttcaac
     4261 acacgcacac actcacacac acactcacac tcacacacac agatatatta aagcacaagt
     4321 ttctattcga cctgccagca ccttctttac tgtggagatg ggacttacgt gaacggcatc
     4381 caccacctcc agggaccttg gtgcgacaca ggcctcatct tgtctgcaca ctgcactgtg
     4441 tctgtctgac cttgccctgt cctgactcaa ggcccaactc cagcccagat gcttgccaga
     4501 agggagctgg atgtgggcaa aatatcagac ttgggctgcc tggatggagg tcacaaggtt
     4561 cagaggcagt ccagtcggga ctccgtgagc tctccgactg tcccttgttc agaggctgac
     4621 aaggaaggga tatctgctgc agagtggaca tgttgctcaa ctcagagtcc ctgacctgtt
     4681 cctaggatgt ccccttcccc tccgtactgt gcccacttgg aagggcccca gccccctgac
     4741 tccgatcagc agctagatgc cactccagat agtcccagct tgggatttcc agggaagcca
     4801 gtgcgtgagg actggtgttt ataccatttt ccaggtgagc attggctttg aggggagcag
     4861 agagtcctgc ctctgtgacc ccatgtcccc acagagaaca atgaactcac agtggagtgg
     4921 atcccgtttc ttaggtattt ggccagagag ttctggaaga gggggtttgg ggggaatgta
     4981 aggcactgtc tagtcagccc tgtggagtac gggggcaggg agggggagag atgaattgag
     5041 gtggttgtgt ctctttgttc cctgggagct gagaaaaggt ttctgtcctc ggaattgata
     5101 gaatagggtc tagaactttt cctctttggg tccctttacc tgctacctag ctttcatggg
     5161 agagcagaat cctagcccct tccaggatga gtctatgtac acgtgcacgt gtgtgtcagt
     5221 gttcaagcgt gtctgtatgc acatctctgc gtgtgtgaga tcccatgtgc ccatccatgt
     5281 ctgtgtacca tcgttggacg ggagtgtgca ggaacacgag gcagtaagta gttagccccg
     5341 tctctgtggg tgagcgtcaa cgtgcagtct tcacctcaaa gacatgtgtg tggggtgctc
     5401 gccctgtctg cagtctcaga ctgcctgcta cagcctttcc acccctctgg atgacaaaga
     5461 gcttgcagat gaccctcttg aaggctagat ccttgcctgg aggcgtgaca caggggctct
     5521 tccctgagca tttgggagga caactggaga gaagaggctg gaaccccggt atcatggcaa
     5581 tagccagagg cacactgaag atcaagaccc ttgctgccta acccccaacc ccacctggcc
     5641 tgtatcacca ccaccaccac cacctccacc tccttcatca tcattgccaa catcactggc
     5701 tgctaaatgg tcaggctaca gccaggcatc ctggtaccca accagtgtgg ctgcccttcc
     5761 tggcccttca agccctttgt ctgaagtgaa ttgctctggt ttccagaaca cgcttctgtg
     5821 acatctgcag ggtattgctc cttaactgtc ccatctgtac tgagtctatt gccccaactc
     5881 gactgtgggt ccctcctgct ctgagcccct ccatcattct tgctgtcact atagtagaaa
     5941 ctgggtggca tggattctat aagccagtag tccctgacca tatagaatca actgagcagg
     6001 ggtcagcctg ggtatagggt gtgatttgat ggcatcagaa tgcagcctgg tattagaaat
     6061 gtgaagaagc ctcttaggac aacccaagag ggaaatctgg ggtcctctca accccagggt
     6121 ctctgggcca gcattgtgct aaagaaatag ctcccccaac tcctcctggg gttcccactg
     6181 taccctgagc ctgctccccc acattgaccc attgtcctga ctgctttaat tgtggggatt
     6241 cttctctata tatcttagag ccggactcag gaaaggtgca cagtatgtgt tagccccgtg
     6301 ttccagaacc ttctctatgg tgacagcagc cgtgcctgaa gggtgtgtgg tctgagattg
     6361 aaaagcctgt ttaaggaacc caccctcata tgcaagtgaa cggggctggg gtgggcatgt
     6421 ctgtgtgagc ccacctttgt gcaggggcgg tgaggccgat ctgcgtgtgc gtgtgtgtgt
     6481 gccggaggca tttaggtgtg tgcagggttg agagtctaag tgtaactgta ggcagggcag
     6541 aagctgtttg cacgtggaag cctgtgtgaa ttggccttcc tgtacctagc cttgagggtc
     6601 catgttgaga ggtgacctgt gaacacccca gtcccaggag accaggctga caggatgtag
     6661 cagatctctt cagtggcagc ctcaccctct gtgttgaggg agctgaggga aactgtggcc
     6721 ttaaagcagg gatcccagag tcaagctctc agggttctgg ggccctttta ctcctggggc
     6781 ccctacaagt tagtgactgg gaggagaata gtattcttgt gaccaggcag tgaagcgcag
     6841 tcagtgggta gcccccgctt ggctgtcctg tccctgggac cacagggacc acaggtaacc
     6901 tctatgaacc ttcattcatc ctcgaagaca aaacctgctt ctccgggcac attcctccca
     6961 taattccctc ttcctcactc accatccttc ttctcctgtt ctccagaagc acccgttcag
     7021 gctgacaggg cctgcacgag actcagaaaa gcaggttttt cacagatttt gaatgcagaa
     7081 gctggaagag agacgggcat gggcaggtct ggctcagttc ttggaggcct agtgctacat
     7141 ccccaggggt gtcctaccgt gagtcactgc tcctgcgaac cccttaccag agtagctaca
     7201 gacagccgag tggaactgac ccttctccgg gcgctctcca tgctgccgag gcccattaca
     7261 cacgtgacag gtgttacttg gatttttttt tttttttttt ttgagagaca aaccatctcc
     7321 ccgtcctact ctggcctctt cttccaggcc acagacacac ctctcccaag gagagcacag
     7381 ttgtcacttg gagattgtca ctgctctctg cacaggagtc tgatgtctca tcatcctgac
     7441 attcttccca gggccaggag agctgcagag gtcatggagt gttcttgggg ttttcctctg
     7501 cttggccagc tccatggggc tgaggaggga cgttcccagg gaatgtccca tgagtgtggt
     7561 gagtgaactc acctgtactg gcgagttcct gcaggctact agctgagctc aggttctggg
     7621 ttcattccgt tctgtcagta ctgggcttat gtatgtgtga gcgctctcgt gtgtgtgtgt
     7681 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtaccgaagg accactcttt tctggagatc
     7741 tcttgaccct tagcactgga agggacctta aaggcatcga atctggtgtg cccactatac
     7801 aggtgtgaaa aactgaggtt cagagagaag gcatctgcct gcccccatcc ttctcccttc
     7861 catgtttggc ctgctttcat tgcccagggg tcctgatata aatgctctcc ctcctagcac
     7921 cctcctgccc tcctctcaaa catcccattc cccccatctc agcccagttc ttcgggaagg
     7981 ggactgctct agggcatccc caaccgttat ccccctctgc cccatggaag tccgatcatc
     8041 aaatgtttat ccccagtcca taagggacag gaaagtaggg actgttcctt ccctagcacc
     8101 ccatagatgg aggaaagcca atcctcccca tatgcccaga cccactcgtc tgccccaccc
     8161 accctgccac cgattaaaag cacaacaggg tgacacgcgt gggtctctcg cgacccccgc
     8221 ctcacccctt tgccttgctc tcttgtctcc acccagcctc tgttacccac cacccatctt
     8281 tctctcttcc acaaacccca aaatgtaacc tctagttgcg gacgcggttg tttcaatcaa
     8341 taaagatgca gtgttctaga a
//
