LOCUS       NM_001191625            7038 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus multiple C2 and transmembrane domain containing 2
            (Mctp2), mRNA.
ACCESSION   NM_001191625 XM_006229375 XM_218795
VERSION     NM_001191625.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7038)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   2  (bases 1 to 7038)
  AUTHORS   Shin,O.H., Han,W., Wang,Y. and Sudhof,T.C.
  TITLE     Evolutionarily conserved multiple C2 domain proteins with two
            transmembrane regions (MCTPs) and unusual Ca2+ binding properties
  JOURNAL   J Biol Chem 280 (2), 1641-1651 (2005)
   PUBMED   15528213
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Oct 6, 2022 this sequence version replaced
            XM_006229375.4, NM_001191625.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643286.1771.1,
                                           SRR26643298.3419.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-169               JAXUCZ010000001.1  135412526-135412694 c
            170-686             JAXUCZ010000001.1  135356936-135357452 c
            687-749             JAXUCZ010000001.1  135349204-135349266 c
            750-858             JAXUCZ010000001.1  135347542-135347650 c
            859-1001            JAXUCZ010000001.1  135332848-135332990 c
            1002-1078           JAXUCZ010000001.1  135331984-135332060 c
            1079-1190           JAXUCZ010000001.1  135331501-135331612 c
            1191-1226           JAXUCZ010000001.1  135327684-135327719 c
            1227-1391           JAXUCZ010000001.1  135317011-135317175 c
            1392-1522           JAXUCZ010000001.1  135314700-135314830 c
            1523-1709           JAXUCZ010000001.1  135305817-135306003 c
            1710-1803           JAXUCZ010000001.1  135303406-135303499 c
            1804-1906           JAXUCZ010000001.1  135288095-135288197 c
            1907-2009           JAXUCZ010000001.1  135286146-135286248 c
            2010-2111           JAXUCZ010000001.1  135265833-135265934 c
            2112-2186           JAXUCZ010000001.1  135264500-135264574 c
            2187-2306           JAXUCZ010000001.1  135262449-135262568 c
            2307-2429           JAXUCZ010000001.1  135230183-135230305 c
            2430-2471           JAXUCZ010000001.1  135227025-135227066 c
            2472-2581           JAXUCZ010000001.1  135208042-135208151 c
            2582-2691           JAXUCZ010000001.1  135193322-135193431 c
            2692-2789           JAXUCZ010000001.1  135186300-135186397 c
            2790-7038           JAXUCZ010000001.1  135179845-135184093 c
FEATURES             Location/Qualifiers
     source          1..7038
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q31"
     gene            1..7038
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /note="multiple C2 and transmembrane domain containing 2"
                     /db_xref="GeneID:308742"
                     /db_xref="RGD:1562967"
     exon            1..169
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            170..686
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     CDS             240..2858
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /note="multiple C2 domains, transmembrane 2"
                     /codon_start=1
                     /product="multiple C2 and transmembrane domain-containing
                     protein 2"
                     /protein_id="NP_001178554.1"
                     /db_xref="GeneID:308742"
                     /db_xref="RGD:1562967"
                     /translation="MDLDKPSVWGSLKQRTRPLLINLSKKKAKKSPSKPLDLRVQHHL
                     DRRLSLSVPDLLEAEALVPEGRPYSGPQSSYISVPNSLSTAGIVPKSSSSSLKQSEEE
                     LEWSQEEASHVPGVDTDSEEIYASPAEEWQAFSQSGLDLHKAPEEPEKTHGSDDLNAS
                     MSSQQFEEQLTLGEASDCVSHLPSPFAYLLTIHLKEGRNLVVRDRCGTSDPYVKFKLN
                     GKTLYKSKVIYKNLNPIWDEIVVLPIQSLDQKLRVKVYDRDLTKSDFMGSAFVVLRDL
                     ELNRTTEHILKLEDPNSLEDDMGVIVLNLNLVVKQGDFKRQRWSNRKRLSASKSSLIR
                     NLRLSESLRKNQLWNGIISITLLEGKNVSGGNMTEMFVQLKLGEQRYKSKTLCKSENP
                     QWQEQFDFHYFSDRMGILDIEVWGKDNKKHEERLGTCKVDISALPLKQDNCLELPLES
                     CQGALLMLITLTPCTAVSISDLCVCPLEDPSERQLISQRYALQNSLKDVKDVGILQVK
                     VLKAADLLAADFSGKSDPFCLLELGNDRLQTHTIYKNLNPEWNKVFTFPIKDIHDVLE
                     VTVFDEDGDKAPDFLGKVAIPLLSIRDGQPNCYVLKNKDLEQAFKGLIYLELDLIYNP
                     VKASIRTFSPREKRFVEDSRKLSKKILSRDVDRVKRLTMAIWNTIQFFKSCFQWESTL
                     RSTVAFVVFLVTVWNFELYMIPLAMLLLFLYNFLRPMKGKASSTQDSQDSTDIEEEEK
                     EEEKESEKKGIIERIYMVQDIVSTVQNILEEVASFGERIKNTFNWTVPFLSLLACLIL
                     AIATVVLYFIPLRYIILLWGINKFTKKLRNPYSIDNNELLDFLSRVPSDIQKVQYAEL
                     KLCGSHSPLRKKRSTV"
     exon            687..749
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            750..858
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            859..1001
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..1078
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..1190
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            1191..1226
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1391
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            1392..1522
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            1523..1709
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            1710..1803
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            1804..1906
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            1907..2009
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            2010..2111
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            2112..2186
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            2187..2306
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            2307..2429
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            2430..2471
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            2472..2581
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            2582..2691
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            2692..2789
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
     exon            2790..7038
                     /gene="Mctp2"
                     /gene_synonym="RGD1562967"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaggaagtcc cgtggctctt gggacgctcc tatgtccttt gcatcagggc tgcttggtgt
       61 tctccggagc agcgagtaca gccacaaggg acagcaacgg cggatcctag gaaagtgagg
      121 ggcgcgcgcc cgccgcgcag tgctggcctg gggactcagt cccagacaga agtcactgac
      181 tgttttccag cagaggcaca ctcttttgag gagtggaact cttgattctt catgcagtta
      241 tggatctgga taaaccatct gtctggggat cactaaaaca gcggactaga ccattgttga
      301 tcaacctgag caagaagaag gctaaaaaga gccccagcaa acctttggat ttaagagtgc
      361 agcatcacct ggaccggcgc ctcagcctct cggtgcctga tctcctggaa gcagaggctt
      421 tggtcccaga aggtcggcct tactcggggc cccagtcatc ctacatctca gtaccaaaca
      481 gcctgtccac tgcaggcatt gtcccgaaga gcagcagcag ctcactgaag caatctgagg
      541 aagagctgga atggagccag gaggaagcaa gccatgtccc tggggtggac accgactctg
      601 aagagatcta tgcctctcct gcagaagagt ggcaggcatt cagccagagt ggcctggatc
      661 tgcacaaagc tcccgaggaa ccagaaaaga ctcatggcag tgacgatctc aacgcttcta
      721 tgtcatctca gcaatttgaa gaacaattga ctcttggaga agctagtgat tgtgtgagtc
      781 acctccccag tccctttgcc tacctcctca ccatacacct gaaggaaggt cgcaacctcg
      841 tggtccggga tcgctgcggc acgagtgatc cgtatgtgaa atttaagctg aacgggaaga
      901 cactgtacaa aagtaaagtg atttataaga acttgaatcc aatttgggat gagatagttg
      961 tcttgccaat acaaagcctt gatcaaaagc tccgtgtgaa ggtgtatgat cgagacttaa
     1021 ccaagtctga tttcatgggt tctgcctttg tcgttctgag ggatcttgaa cttaacagga
     1081 ctactgaaca cattttaaaa ttggaagatc caaacagttt agaagatgat atgggtgtga
     1141 ttgtactaaa tctgaaccta gttgtaaaac agggcgattt caagaggcag cgttggtcaa
     1201 atcggaagcg gttaagtgcc agcaagtcct ccttgatccg caacttacgc ctctcggagt
     1261 ccctgcggaa gaaccagctc tggaatggga ttataagcat aactctgttg gaagggaaga
     1321 atgtctcagg aggcaacatg acagagatgt ttgtccagtt aaaactggga gaacagaggt
     1381 acaaaagcaa gacactgtgt aagagtgaaa atccgcagtg gcaggaacag tttgactttc
     1441 actacttctc tgacaggatg ggcattttgg acattgaagt gtggggaaag gacaacaaaa
     1501 agcatgagga gcgactgggc acgtgtaaag tagacatctc agcgctccca ctgaagcaag
     1561 acaactgcct ggagctacct ctggagagct gccagggggc tctcctcatg ctgatcaccc
     1621 tgaccccctg tactgcagtc tccatctctg atctctgtgt ctgcccttta gaggacccca
     1681 gtgaaagaca gctgatttcc cagcgatacg ccttacagaa ctctctgaag gatgtgaaag
     1741 acgttggtat tctccaggtg aaagttctga aggccgcaga cctcctggca gctgacttct
     1801 cagggaagag cgatcctttc tgcctattgg agttgggcaa tgaccgactt cagacacata
     1861 ccatttacaa aaacctcaat cctgagtgga acaaagtttt tacattccct attaaagata
     1921 tccatgatgt gttggaagtg acagtgtttg atgaggacgg agacaaggcc ccggactttc
     1981 ttgggaaagt tgccatcccc ttgctgtcta ttagagatgg acaacctaat tgctacgtgt
     2041 taaagaataa agatttagag caagcattca aggggctcat ttacttagag ttggacctca
     2101 tctataatcc ggtcaaagca agtatcagga ccttcagtcc aagagaaaaa cggtttgtgg
     2161 aagacagccg caagctgtcc aaaaagatat tatcgagaga tgtagaccgt gtaaaaagac
     2221 tcactatggc catatggaac acaatacagt tcttcaaaag ctgcttccaa tgggagtcta
     2281 cattaaggag tacagtagca tttgtggtgt ttttggtcac cgtctggaat tttgaactct
     2341 acatgatccc tctggcaatg ttgctactct ttctgtacaa cttccttaga cccatgaaag
     2401 ggaaagccag cagcacccag gacagccagg atagcacaga catagaggag gaagagaaag
     2461 aggaagagaa ggagtctgag aaaaagggaa taattgagag aatctatatg gtccaggata
     2521 ttgtttccac tgtccagaac atcttggagg aagtcgcttc ttttggagaa aggattaaga
     2581 acacatttaa ctggacagtg cccttccttt cgctgctggc ctgtttgatt ctggccatag
     2641 ccacggtcgt tttgtatttc attcctctac ggtatatcat tctactctgg ggcatcaata
     2701 aatttactaa gaagcttcga aatccttatt ccatcgacaa taatgagctc ctcgactttc
     2761 tctccagggt gccctctgac attcagaagg tgcagtatgc agagctgaaa ctctgtggca
     2821 gccacagccc acttcggaag aagaggagca ctgtctaggg ttcacacaga ctgcaaactc
     2881 cagcatccaa tgtgcagcca gtcagacctg gatcctggct gctctagtgg taccaaggtg
     2941 tcctaagatg tctgttcagc ctgttcatcc ctctctgttc tctttacata cccagatgca
     3001 agcacacgtg cacacaggtc tctatgcatg ggtatcccag atgcctagac aaccaaacca
     3061 tcaacaggca tcaagtctga gactgtgcga gcctcgcgtc cacttttagg acataagaca
     3121 aggtgtccac atgtctgaac accatccttg agaataacca ggagaccact tgattctggg
     3181 atgatgctga actgatttca ataccatcag tggatttttc actaaaaatg attagttatt
     3241 tttagttgag gctggtggtt cacaactgta atcctaacag cgaagaggcc aacgcaggac
     3301 agtccaagct caatgccagc tcaggaattg tgctatgtcg gcctccactc tatagtaaaa
     3361 actctgtctt aaaaccgaca atcaacagaa gttcagttat ttccagtctt gatcccctga
     3421 cttgtcccat gttattttgc ttctctctat ctacccagaa atgaatatta gaaaatgaat
     3481 atttagtgat ttccagaatt aactcaaata tttaggaagc tttcagctgt gattactaaa
     3541 gacatgctta tttatttatt tttggtggcc ccttagtatt agatgccagt ttaaatcaca
     3601 tctcagctgt tgttggcaag ggctattcct gaaggtccca aagagacact cattggagtc
     3661 actcattgga agaataaggg ttttgtggta gtattaggtt tctgtaaaat gccatttctt
     3721 ccagcatcac ttttttgctt attactaaaa caagatgtca atgtgcaccc ttagagagat
     3781 gctgaaggtt ggggcagatg aattggtaga ttctgaatgt atttagtaat atccaagtat
     3841 gacggggctt atttaactga gactcttagt gaaatctaat catttcggtt gtctgatgtt
     3901 ttgagcagac atttaaaatg tttttgctgt tccaaacttg tcttttattt ttctaaggat
     3961 caatataagg tatagacaat ggaagcttat ttcaaaaatc ctggtcatac caaacaacca
     4021 ccaaaaattc ctctatagag agtatttgaa tcctgagtac cctgcaaccc cacagcatac
     4081 cctgctaagt ttaaaacaat taatgatgtg catgtaaaaa gtgtacaaat atatcttttt
     4141 attaaaatga tatttaagct ttaaaatcta tatttcatca gcatatactt gctatgtgca
     4201 gatttgtata tgtattgtaa agagaagctg aggtaagaag acgtaattca cttgtgttta
     4261 gctctttttt ttgtttctgc attgtaattt aataatcttc aaacaaaatg ttttatgaaa
     4321 aaaaatgcca aagactctaa actttgtcat ctcctgtctg ttttacttcg tattcttctt
     4381 cctgatttct ctgtgacaga gcccgatttc tgcatgattt gatttacttc aagttaatga
     4441 ggctggctgg gaaagagcct tgacgagatt ctaaaagccc cagtaaatct gttagttgta
     4501 catacaatag atacccgaga acttctttgt ctaaccagtt actcaatctt ctgtgtaaac
     4561 aatacctcat tgtcttattc ctgtcatcca gtttatcata gtctgtcatt tagtaatgac
     4621 ccaaggcaga catctataag ccatcatgtg agataagagc agccattgga atggaaactt
     4681 tggagagcca aataatccct tatttattta aatgtaggac ccatccttca tagctgttct
     4741 tttcctttag aatttctaaa tgaaataatt ttcccaacag gaaggtatta ttagtgcgac
     4801 ttctttcccc catatccccg atagaactca cagcattaaa ttcaggtcac aaatgccaac
     4861 tggtatttga gagcaagttg gggccaactt tttctatact ctactgaaga caattgagaa
     4921 tttatgaaat caacattgca tgtgagaaaa tgagtattcg ttggaagtga aatgttaaga
     4981 ttcatacaat tatttgtagt tgcacaggtc tcatccttat atgctttgtc ttagcccagg
     5041 atgtcagaga gtgacaaatc gtataatcta atactttatt ccatcttgac gaagcacctg
     5101 tcatggtgct gtaggcagaa ttattctcct tgtattcatg ggaccaaagc tagcatgaat
     5161 ttcttttttt tccttcttcc actgtttgat ataagaaaga aagatttgtt ctaaccccaa
     5221 aatgtatgaa cttctgcaag acttttctcc tttctgagaa ttatcacaat tgatacttat
     5281 agaaagaagt cctttggcat gtccaaattt gccagctaat ttgacagttt gtatgttttg
     5341 agacaagcac tgagtaacat gcatgttact aaatcaccac agtcataaat ctgatagctt
     5401 gtggccactc tataaagaca aaagatccaa aggaaagcta aattctcaca ccactacagt
     5461 ccagccacaa gagtttgaag ccttgtttct tagtgaccca agatctctca tacaaacatc
     5521 tggagcctaa ctcataaact ctcacagcac tttacacgaa aggccagtct ttaaagcatg
     5581 agttgtgtta tatgttaaag cttgctgttt agcaaggtat cgggaaattc acctatccct
     5641 tcagacatgg accaacccgg gagtcccaca atgaaagaat ggagtcattt ctccttttcc
     5701 tgcaataaaa taactccacc tgcttctgtg agtgacatga ttccctctct ctagaaactc
     5761 actgtttcat tggagtgtgt ttcaataaat tatatattta tgtcttggta aattatttta
     5821 tcagtacata actctctttc ctatattgga ttacattggc aactactatg tgactaacag
     5881 gcaagtagca tatgcaatgt gaatactttg aatgaagact gactcacatt caagacaagg
     5941 tgggctacaa gatgcacgat gcagatccat tattcagagc atatggtatc cacttaatga
     6001 ttttgttgaa attagtagat gacatattca tactactcaa cctaaagata attaattggg
     6061 aatgttaaag ctttgtaaag tgttcacagt tcccttcttt gtcccacact cacttttaga
     6121 gcactgccaa agtcttatct taaaggcttg tcttctgaac tggggccagg gatctcttgg
     6181 atatctttga ttttggtctt tgtgtttttc cctcatctac aaacctatgt aatccagtca
     6241 gtcagggctg gatatagtat tgcttctcct ggtagccata ctgcgtaata ttccatatgt
     6301 catgggaatg aggggaatct cattgagctg ggttagtctt catattagct cttccacttt
     6361 tgatgacttt ccctaaatgt ctaagtagat gctattctcc ttcaagtttg aagttctcct
     6421 gctctgatgg tgtcaccttt gactttgtgc tatctgagtt tccacctcct gatacagcat
     6481 aagatgggga aggcctcagt gaattggtga gtgctaaccc atgtgtctcg gtgaaccact
     6541 actgtcatca tgaagtcact ttatccttct agctaccttc caaatcccct accttcaaac
     6601 aatgtgtcat agccaatgat ttgagatcaa agtttgagga aatgaattct aacagataca
     6661 ccaaaacatc aaaaatcatc tgtatatcta ctgaaggtca gagcttccag aggccttggc
     6721 cccactcttc tctactagac ataccagtct ataagccact cagaaataca tgcctaacag
     6781 cacaatcatg ggccatttat ttctgagtct ttttatatgt tgcttctttt tttaaagaaa
     6841 aaagagaaag gaataaccca gaaagatcaa tggtgcccat cctggacagt gagtgattgc
     6901 atgaagtaga gtgcttattt tgtgtgatag atatgacttc tggatatgtc aatgaccaac
     6961 tattcaatta tgcaatgtct tgtatttgga gaaattctta catggcaata gaaaatacag
     7021 tgtttgtgaa ttgtaaaa
//
