LOCUS       NM_001376934            4778 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus multiple C2 and transmembrane domain containing 1
            (Mctp1), mRNA.
ACCESSION   NM_001376934 XM_017591152 XM_017594233
VERSION     NM_001376934.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4778)
  AUTHORS   Qiu,L., Yu,H. and Liang,F.
  TITLE     Multiple C2 domains transmembrane protein 1 is expressed in CNS
            neurons and possibly regulates cellular vesicle retrieval and
            oxidative stress
  JOURNAL   J Neurochem 135 (3), 492-507 (2015)
   PUBMED   26195140
REFERENCE   2  (bases 1 to 4778)
  AUTHORS   Shin,O.H., Han,W., Wang,Y. and Sudhof,T.C.
  TITLE     Evolutionarily conserved multiple C2 domain proteins with two
            transmembrane regions (MCTPs) and unusual Ca2+ binding properties
  JOURNAL   J Biol Chem 280 (2), 1641-1651 (2005)
   PUBMED   15528213
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On or before Dec 3, 2019 this sequence version replaced
            XM_017591152.1, XM_017594233.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.8859.1,
                                           SRR26360194.919624.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-799               JAXUCZ010000002.1  7803484-7804282
            800-914             JAXUCZ010000002.1  8066945-8067059
            915-1057            JAXUCZ010000002.1  8153868-8154010
            1058-1137           JAXUCZ010000002.1  8179491-8179570
            1138-1249           JAXUCZ010000002.1  8184289-8184400
            1250-1288           JAXUCZ010000002.1  8192388-8192426
            1289-1459           JAXUCZ010000002.1  8212986-8213156
            1460-1590           JAXUCZ010000002.1  8224989-8225119
            1591-1777           JAXUCZ010000002.1  8238409-8238595
            1778-1871           JAXUCZ010000002.1  8243356-8243449
            1872-1974           JAXUCZ010000002.1  8259777-8259879
            1975-2077           JAXUCZ010000002.1  8261581-8261683
            2078-2179           JAXUCZ010000002.1  8262011-8262112
            2180-2254           JAXUCZ010000002.1  8262579-8262653
            2255-2374           JAXUCZ010000002.1  8264513-8264632
            2375-2494           JAXUCZ010000002.1  8351596-8351715
            2495-2548           JAXUCZ010000002.1  8381391-8381444
            2549-2658           JAXUCZ010000002.1  8484793-8484902
            2659-2768           JAXUCZ010000002.1  8487920-8488029
            2769-2866           JAXUCZ010000002.1  8490426-8490523
            2867-4778           JAXUCZ010000002.1  8491685-8493596
FEATURES             Location/Qualifiers
     source          1..4778
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q11"
     gene            1..4778
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /note="multiple C2 and transmembrane domain containing 1"
                     /db_xref="GeneID:309928"
                     /db_xref="RGD:1305199"
     exon            1..799
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     CDS             98..2938
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /note="multiple C2 domains, transmembrane 1, pseudogene 1"
                     /codon_start=1
                     /product="multiple C2 and transmembrane domain-containing
                     protein 1"
                     /protein_id="NP_001363863.1"
                     /db_xref="GeneID:309928"
                     /db_xref="RGD:1305199"
                     /translation="MEPRGAAAGEPEPAVSPSFQARLWKNLQLGVGKGKGGGGGRAGG
                     PERRTAATPTPSLPPPKTTQDVGSTGSRWSGFKKRKQVLDRVFSSSQPNLCCSSPEPL
                     EPGGAGRAEQGSTLRRRLREHLLPVAKGSSTAAGTVGVTPPGGRSPDSAPSSSASSSL
                     SSSPQPPPRGDRIRDEGTRRGSPEAHLCHQKSSSLPGTACLEQLLEPAPPPAEPARRP
                     AEPQSLQKGEELDCSQKINPVETSNADVPLADPGMYQLDITLRRGQSLAARDRGGTSD
                     PYVKFKIGRKEVFRSKIIHKNLNPVWEEKACVLIDHLREPLYIKVFDYDFGLQDDFMG
                     SAFLDLTQLELNRPTDVTLTLKDPHYPDHDLGIILLSVILTPKEGEPRDVTMLMRKSW
                     KRSSKFQTQSLRLSDQHRKSHLWRGIVSITLIEGRDLKAMDSNGLSDPYVKFRLGHQK
                     YKSKIMPKTLNPQWREQFDFHLYEERGGVMDITAWDKDAGKRDDFIGRCQVDLSSLSR
                     EQTHKLELQLEEGEGHLVLLVTLTASATVSISDLSVNSMEDHKEREEILKRYSPLRIF
                     NNIKDVGFLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVF
                     TFNIKDIHSVLEVTVYDEDRDRSADFLGRVAIPLLSIQNGEQKAYVLKNKQLTGPTKG
                     VIHLEIDVIFNAVKASLRTLIPKERKYIEEENRLSKQLLLRNFIRTKRCVMVLVNAAY
                     YVNSCFDWDSPPRSLAAFVLFLLVVWNFELYMIPLLLLLLLTWNYFLIISGKDNRQRD
                     TVVEDMLEDEEEEDDRDDKDGEKKGFINKIYAIQEVCVSVQNILDEAASLGERVKNTF
                     NWTVPFLSWLAIIALCVFTAILYFIPLRYIVLVWGINKFTKKLRSPYAIDNNELLDFL
                     SRVPSDVQVVQYQELKPDHSHSPYKRKKNNLG"
     exon            800..914
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1057
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1137
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            1138..1249
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..1288
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            1289..1459
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            1460..1590
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            1591..1777
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            1778..1871
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            1872..1974
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            1975..2077
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            2078..2179
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            2180..2254
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            2255..2374
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            2375..2494
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            2495..2548
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            2549..2658
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            2659..2768
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            2769..2866
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
     exon            2867..4778
                     /gene="Mctp1"
                     /gene_synonym="Mctp1-ps1; RGD1305199"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgctggccgc cgccgccgcc tccacgctcc cggaggacgc tcagcccgag agggaagaga
       61 agcagtaggt ggggagcgga ggtgcccagc ttggaggatg gagcctcggg gtgcggcggc
      121 tggcgagccc gagccggccg tgtccccctc cttccaggcc cggctctgga agaacctgca
      181 gctgggggtg ggcaagggca agggcggcgg aggcgggcgc gctgggggcc ccgagcgccg
      241 cactgcggcc actccgaccc catctctgcc gcccccgaag accacgcagg acgtggggag
      301 tactggcagc aggtggagcg gcttcaagaa gcggaagcaa gtgctggacc gagtgttctc
      361 ttcctcgcag cccaacctgt gctgctcctc accggagccc ctggagcctg gcggagcagg
      421 cagagcagag caggggtcca cgctgcgccg ccgcctacgg gaacatctgc tgccggtggc
      481 taaagggtcc tctacagccg cggggacagt cggagtgacg cctccaggcg gacgctctcc
      541 ggactcagct ccttcttctt ctgcctcatc ctccctgtcc tcttctcccc aaccgccccc
      601 gaggggggac cgcatccgag atgagggcac acggcgtggg agtcctgagg cgcacctgtg
      661 ccaccaaaag agctcctctc tgcccggtac cgcgtgcctg gagcagttac tggaaccagc
      721 gccacctccc gcagaaccgg cccggcgtcc tgccgagccc cagtctctgc agaagggcga
      781 agagcttgac tgcagccaga aaataaatcc agtcgaaacc agtaatgcag atgtaccttt
      841 ggctgatccc ggaatgtacc agttggacat cacactaaga aggggtcaaa gtttagctgc
      901 ccgtgatcga ggagggacca gtgatccata tgtgaagttt aaaattggaa gaaaagaagt
      961 ttttagaagt aaaattatcc acaagaacct aaatcctgtg tgggaggaaa aagcttgcgt
     1021 gctcattgac catcttagag agccactgta tatcaaggta tttgactatg attttggact
     1081 gcaagatgac tttatgggct cagcctttct cgatctcaca cagttggagt taaacaggcc
     1141 cacagatgtc accttaactc tgaaagatcc ccattatcct gaccatgacc ttggaatcat
     1201 tttgctgtca gtcatcctta cgcctaagga aggtgaaccc agggatgtga caatgctaat
     1261 gaggaagagt tggaaaagat ccagtaagtt tcagacccaa agtttacgtc tgtcagacca
     1321 gcacaggaaa tcacatctgt ggagaggaat agtcagcatc accttgattg aagggcgaga
     1381 cctcaaagca atggattcca atgggttgag tgatccatat gtgaagttcc ggcttggcca
     1441 tcagaaatac aagagcaaga ttatgcccaa aactttgaac cctcagtgga gggagcaatt
     1501 tgatttccat ctctatgagg aaagaggcgg agtcatggac atcactgcct gggacaaaga
     1561 tgctgggaaa agagatgact ttattggaag gtgccaggtt gacctgtcgt ccctcagtag
     1621 ggagcaaaca cacaagctgg agttacagct ggaagagggt gagggccacc tggttctact
     1681 tgtcactttg acagcctcgg ccacagtcag tatctctgac ctctctgtca actccatgga
     1741 ggaccacaag gagcgggaag agatattaaa gagatatagc ccactgagga tatttaacaa
     1801 cataaaagat gtgggatttc tccaggtgaa agtcatcaga gcagaaggtt tgatggctgc
     1861 agatgtcaca ggtaaaagtg atccattttg tgtagtagaa ctgaacaatg acagactgct
     1921 aacacatact gtgtacaaaa acctcaatcc tgagtggaat aaagtgttca cattcaacat
     1981 taaagacatt cattcagttc ttgaagtgac agtttatgat gaagatcgtg accggagtgc
     2041 cgactttctg ggcagagtcg ctataccatt gctgtctatt caaaatggtg aacagaaagc
     2101 ctacgtcttg aaaaacaagc agctgacagg gccaacaaag ggggtcatcc atcttgaaat
     2161 agatgtgatt tttaatgctg tgaaagccag cttacgaaca ttaataccca aagaacggaa
     2221 gtacattgaa gaggaaaaca gactctctaa acagctgctt ctaagaaact ttatcagaac
     2281 aaaacgttgt gttatggtgc ttgtaaatgc tgcatactac gttaatagtt gctttgattg
     2341 ggattcgccc ccaaggagtc ttgctgcttt tgtgctcttt ctccttgttg tctggaactt
     2401 tgagctgtac atgatacccc tgctgctgtt gttactactg acatggaact acttcctaat
     2461 aatatctggg aaagataaca ggcaacggga cacagtagtg gaggacatgc tggaggacga
     2521 ggaggaagaa gatgacagag atgacaagga tggtgaaaaa aaaggattta taaataaaat
     2581 ctatgccatc caggaagtgt gtgtcagtgt ccagaacatc ctagatgaag cggcttccct
     2641 tggggaaagg gtaaagaata ctttcaactg gactgtcccg ttcttaagct ggctggccat
     2701 tatagccctc tgtgtgttca cggccattct gtacttcatc ccactgagat acattgttct
     2761 tgtctgggga attaataaat ttacaaaaaa gcttcggagt ccatatgcaa ttgataacaa
     2821 tgaactactt gacttccttt ccagagttcc ttcagatgta caagtggtgc aatatcaaga
     2881 actgaaacca gatcattctc atagcccgta taaaaggaag aaaaacaacc ttggttagtc
     2941 tgttcccagc accgaggaga ccagcatgtt tgggaagata aaagaaaaaa aaatcgtcgg
     3001 gctacgcagc atttcctctc tttctgcttt ttatttattt taccttttta tcagggtcaa
     3061 gaacatttgt aaatagtgta caaaaggcat atgtctttga aaatatactt ctcctgtaca
     3121 gactcaactt gataagggat tttagctagt ggagtgtgga aaccttgtta gctgcagcta
     3181 ataacataac caagtaaaat aaaacaatgg ttataaaact ggaagatgta tatttctcca
     3241 atcacaaaag agagaaccag aatatcagat taaatgctca attgtgctct ggttaaccct
     3301 ccataaaacc taaatgctga tttgatcttt aggttttttt ttttgtaatg taactatttc
     3361 ttatctgaaa agtaattcat tagtgttttt tctttttatg tttatacatt acaaatgggg
     3421 ggagggatcc catagcttga ataatggaaa tgttgcactt caacttaaca tacatcctga
     3481 ctttcacttc tgtgtaaata aattatgtat ggctaaggct gattttaagc tacaggtaca
     3541 ttcatatctt ttcctgtctg catacataca caatccctta agagaatctg agagtctatg
     3601 aataagactt ttaagccttc tatcattcca tctaaaacct taaaatctct ccagaaacta
     3661 tattaaataa atactgccag gtttataaat gattgagtat caggattttt ataattatat
     3721 tactgtgttt agcaaattat caagccaatt ctcaaaaaat actagcaaac taaatcccta
     3781 ctgtatttgg tatcaaatta tgcccttgtg catttaaaag tgtagtattt aagtgtcctc
     3841 tactgataga cttcaatgca tactgagttt tgtttttagt gagttttaat ggagaatgca
     3901 gttggctaag tgaaaggcca gtgttttcat tacatcattt atgaaggaag atcattgata
     3961 atgcatgaaa atctgttttg taaaataaac tgcttgtaag gtggtttcca ttaaaaatgt
     4021 ttcactaacc acactctata cttcaaattg cattcctaaa acagggtcta tcaaaggaac
     4081 atacctctgc agagataaga aatttggttg gtgagaatgt cctcactgac tttttagagg
     4141 aatgagactc aatggaaatt gctgcagaca atgttttgca ctattttatt aattgctatt
     4201 aataaataac tggggtgagg tgaagattgg ggttgtgctg gaaaatgtag aaaagcagaa
     4261 atatatattt gaatttaaag attctttaaa tctcatcgaa gctgattttt aaagtatttt
     4321 tattttagaa atatgttatt aaatagtatt tcttacaata gaactatttt gatgtttata
     4381 tactatgctt ggaagaatgt caactaaatt ccctttctac agaaagactt tgacctcaat
     4441 atgctctatt tagtgtatca tgtttaaaat gctttccatt actgtttgtt gcaaaaacat
     4501 actttatgaa gctgacctaa tacatagttt attgatgagc tcattaattt ggtataaatt
     4561 ctgattatac ctgtgagatt tatgttctgt gctgacaatg tctattcaaa tgtctataag
     4621 cctgacattc tataaccttg gatgtaccta gtggatgtaa ccattaacag atgactaatt
     4681 tttgtttatt tcattgtgta agatttcaga tgtttagttc aatagtaatg ttgactacat
     4741 attcactgca ttaaacacaa aagaagttaa tcatttta
//
