LOCUS       NM_019321                943 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Rattus norvegicus mast cell protease 4 (Mcpt4), mRNA.
ACCESSION   NM_019321
VERSION     NM_019321.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Karlson,U., Pejler,G., Froman,G. and Hellman,L.
  TITLE     Rat mast cell protease 4 is a beta-chymase with unusually stringent
            substrate recognition profile
  JOURNAL   J Biol Chem 277 (21), 18579-18585 (2002)
   PUBMED   11896050
  REMARK    GeneRIF: investigation of substrate recognition profile
REFERENCE   2  (bases 1 to 943)
  AUTHORS   Lutzelschwab,C., Pejler,G., Aveskogh,M. and Hellman,L.
  TITLE     Secretory granule proteases in rat mast cells. Cloning of 10
            different serine proteases and a carboxypeptidase A from various
            rat mast cell populations
  JOURNAL   J Exp Med 185 (1), 13-29 (1997)
   PUBMED   8996238
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from U67907.1.
            
            On Feb 21, 2013 this sequence version replaced NM_019321.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U67907.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680420 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-943               U67907.1           3-945
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p12"
     gene            1..943
                     /gene="Mcpt4"
                     /note="mast cell protease 4"
                     /db_xref="GeneID:54270"
                     /db_xref="RGD:3064"
     exon            1..68
                     /gene="Mcpt4"
                     /inference="alignment:Splign:2.1.0"
     CDS             14..754
                     /gene="Mcpt4"
                     /note="rMCP-4; rMCP-IV; mast cell protease IV"
                     /codon_start=1
                     /product="mast cell protease 4 precursor"
                     /protein_id="NP_062194.1"
                     /db_xref="GeneID:54270"
                     /db_xref="RGD:3064"
                     /translation="MKALLFLMALLLPSGAGAEEIIGGVESIPHSRPYMALLKIVTEE
                     GHVTFCGGFLISLQFVLTAAHCHGREITVTLGAHDMSKRESTQQKIKVVKQIFPLKYN
                     LFSNFRDIMLLKLEQKAVLTPSVNVIPLPQSSDIIKPGTMCLAAGWGQTGVKEPNSNT
                     LREVMLRIMEMKACKDYRHYDNRFQICVGIPQMLKLAYKGDSGGPLVCAGVAHGIVSH
                     GPGRGIPPIIFTRISSYVSWINRVIRGN"
     exon            69..219
                     /gene="Mcpt4"
                     /inference="alignment:Splign:2.1.0"
     exon            220..355
                     /gene="Mcpt4"
                     /inference="alignment:Splign:2.1.0"
     exon            356..610
                     /gene="Mcpt4"
                     /inference="alignment:Splign:2.1.0"
     exon            611..931
                     /gene="Mcpt4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 taccgctggc acaatgaagg ccctgctatt cctgatggct cttctcttgc cttctggagc
       61 tggagctgag gagattatcg gtggtgtgga gtctattcct cactcccgcc cttacatggc
      121 ccttctgaag atcgtcactg aagaaggtca tgtgaccttc tgtggtgggt ttctcataag
      181 ccttcaattt gtgctgactg ctgcacactg tcatggaagg gaaatcactg tcaccctcgg
      241 agctcatgac atgagcaaga gagaatccac acaacaaaag ataaaagttg taaaacaaat
      301 ctttcctcta aagtacaatt tattttccaa tttccgtgac atcatgttac tgaagcttga
      361 acagaaagca gtgttgactc cgtctgtgaa tgtaatcccc ctgcctcagt cctctgacat
      421 tatcaagcct gggacaatgt gcttggcagc tggatgggga caaactggag tgaaagaacc
      481 gaactcaaat acactgaggg aggtcatgct gagaatcatg gaaatgaagg cctgtaagga
      541 ctataggcat tatgacaata gattccagat ctgcgtgggg attcctcaaa tgttgaaatt
      601 agcatacaag ggagactctg gaggacctct agtgtgtgct ggagtggccc atggtattgt
      661 atctcatggc cctggaagag gaatcccccc tataatcttc acccgaatct cctcatatgt
      721 gtcctggatt aatagagtca taaggggaaa ttagctgaaa aacctgatca gcctgagtca
      781 gagtctccaa gccacagctc ttctgttaaa tctctttggt tttaacaaaa cctgactcac
      841 cctgtcccca agacaatctc aaaaatacac aagtctgtca tgatggattg ttccctgtaa
      901 tgctcctaaa taaagacata accccttgca aaaaaaaaaa aaa
//
