LOCUS       NM_017146                861 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus mast cell protease 10 (Mcpt10), mRNA.
ACCESSION   NM_017146 XM_001058119 XM_008770717 XM_017599880 XM_039093843
            XM_341322
VERSION     NM_017146.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 861)
  AUTHORS   Lutzelschwab,C., Pejler,G., Aveskogh,M. and Hellman,L.
  TITLE     Secretory granule proteases in rat mast cells. Cloning of 10
            different serine proteases and a carboxypeptidase A from various
            rat mast cell populations
  JOURNAL   J Exp Med 185 (1), 13-29 (1997)
   PUBMED   8996238
REFERENCE   2  (bases 1 to 861)
  AUTHORS   Amerik,A.Yu., Yarovoi,S.V., Grigorenko,V.G. and Antonov,V.K.
  TITLE     Identification, sequence analysis, and characterization of cDNA
            clones encoding two granzyme-like serine proteinases from rat
            duodenum
  JOURNAL   FEBS Lett 324 (2), 226-230 (1993)
   PUBMED   8508925
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On or before Jul 5, 2022 this sequence version replaced
            XM_039093843.1, NM_017146.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360186.1277564.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680423 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-84                JAXUCZ010000015.1  33888629-33888712   c
            85-235              JAXUCZ010000015.1  33887310-33887460   c
            236-368             JAXUCZ010000015.1  33886853-33886985   c
            369-623             JAXUCZ010000015.1  33886376-33886630   c
            624-861             JAXUCZ010000015.1  33885728-33885965   c
FEATURES             Location/Qualifiers
     source          1..861
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p12"
     gene            1..861
                     /gene="Mcpt10"
                     /gene_synonym="GLP II; GLP-2; rMCP-10; rMCP-X"
                     /note="mast cell protease 10"
                     /db_xref="GeneID:54269"
                     /db_xref="RGD:3063"
     exon            1..84
                     /gene="Mcpt10"
                     /gene_synonym="GLP II; GLP-2; rMCP-10; rMCP-X"
                     /inference="alignment:Splign:2.1.0"
     CDS             30..776
                     /gene="Mcpt10"
                     /gene_synonym="GLP II; GLP-2; rMCP-10; rMCP-X"
                     /note="granzyme-like protein 2; mast cell protease X;
                     granzyme-like protein II"
                     /codon_start=1
                     /product="granzyme-like protein 2 precursor"
                     /protein_id="NP_058842.3"
                     /db_xref="GeneID:54269"
                     /db_xref="RGD:3063"
                     /translation="MFLFLIFLVAVLPVNTEGGEIVWGTESKPHSRPYMASLMFYYGN
                     SYRHYCGGFLVAKDIVMTAAHCNESNIKVILGAHNIKKRENTQVFSVVKAKPHENYDS
                     HSLFNDIMLLKLERKAQLNGVVKTIALPRSQDWVKPGQVCTVAGWGRLANCTLSNTLQ
                     EVNLEVQKGQKCQGMSEDYNDSIQLCVGNPSEGKATGKGDSGGPFVCDGVAQGIVSRR
                     LCTGTLPRVFTRISTFIPWIQKTMKLLQQP"
     exon            85..235
                     /gene="Mcpt10"
                     /gene_synonym="GLP II; GLP-2; rMCP-10; rMCP-X"
                     /inference="alignment:Splign:2.1.0"
     exon            236..368
                     /gene="Mcpt10"
                     /gene_synonym="GLP II; GLP-2; rMCP-10; rMCP-X"
                     /inference="alignment:Splign:2.1.0"
     exon            369..623
                     /gene="Mcpt10"
                     /gene_synonym="GLP II; GLP-2; rMCP-10; rMCP-X"
                     /inference="alignment:Splign:2.1.0"
     exon            624..861
                     /gene="Mcpt10"
                     /gene_synonym="GLP II; GLP-2; rMCP-10; rMCP-X"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agttgagacc tggtcagacc ctgaagagga tgttcctgtt cctgatcttc ctggtggctg
       61 tcctaccagt caacactgaa ggaggagaga tcgtatgggg tacagagtcc aaaccccact
      121 cccggcccta tatggcatcc ttaatgtttt attatggtaa ttcatatcgc cattactgtg
      181 gtggtttcct ggtggcaaaa gacatcgtaa tgacagcagc tcactgtaat gaaagcaata
      241 taaaagtaat cttaggtgct cacaatatca agaaacgaga aaacacccag gtcttctctg
      301 ttgtaaaagc caaacctcac gagaactatg acagccattc actgtttaat gacatcatgc
      361 tcctgaagtt ggaacgcaaa gctcaactca atggtgttgt gaagactatt gcccttccta
      421 ggagccagga ctgggtgaaa cctgggcagg tgtgcacagt ggcaggttgg ggacgcttgg
      481 ccaattgtac tttgtctaac acacttcaag aagtgaatct agaagttcag aaaggccaga
      541 agtgccaagg catgtcagaa gactacaacg actccatcca gctttgtgtg ggaaacccca
      601 gcgaggggaa ggctactggt aagggagact cagggggtcc ctttgtgtgc gatggagtgg
      661 cccagggcat tgtcagtcgt cgcttgtgta ctgggacact tcctcgagta ttcaccagaa
      721 tctccacctt tataccgtgg attcagaaaa caatgaaact ccttcaacaa ccctagaaca
      781 caaaacctgt gtctgggcca atgtccagcc tcctggggta tggctatcta agtcttaata
      841 aagaaatctg tctgcaggaa a
//
