LOCUS       NM_001039005            2547 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus mucolipin TRP cation channel 2 (Mcoln2), mRNA.
ACCESSION   NM_001039005 XM_214737
VERSION     NM_001039005.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2547)
  AUTHORS   Sun L, Hua Y, Vergarajauregui S, Diab HI and Puertollano R.
  TITLE     Novel Role of TRPML2 in the Regulation of the Innate Immune
            Response
  JOURNAL   J Immunol 195 (10), 4922-4932 (2015)
   PUBMED   26432893
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC099787.1.
            
            On Jan 12, 2006 this sequence version replaced XM_214737.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099787.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN11044071, SAMN16676785
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2547
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q44"
     gene            1..2547
                     /gene="Mcoln2"
                     /note="mucolipin TRP cation channel 2"
                     /db_xref="GeneID:292168"
                     /db_xref="RGD:1308884"
     exon            1..126
                     /gene="Mcoln2"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..1750
                     /gene="Mcoln2"
                     /note="mucolipin 2"
                     /codon_start=1
                     /product="mucolipin-2"
                     /protein_id="NP_001034094.1"
                     /db_xref="GeneID:292168"
                     /db_xref="RGD:1308884"
                     /translation="MPEGEETLDLPAWNRAPDPAWGPQHRAAVASLDSEVKEECLRED
                     LKFYFMSPCEKYRARRQIPWKLALQILKIVMVTTQLVRFGLGNQLVVAFKEDNTVAFK
                     HLFLKGFSGVDEDDYSCSIYTQEDAYESIFFAIKQYRHLKNISLATLGYGKSEDNRTG
                     LRFCKQHYKSGAMFSSNETLNIDSDIETDCTHLDLQVLTKDPEDWAQASFFRLDFHRL
                     VQVDISFALKGIDLQAVHSREVPDCYLFQNTITFDNTAHSGKIKIYFNSEANIEECKH
                     MNLSGSLQRSTRYVLVFDVFVIAICLASLILCTRSIVLALRLRKRFLNFFLEKYKQHV
                     CDADRWEFINGWYVLVTISDLMTIIGSILKMEIKAKNLTNYDLCSILLGTSTLLVWVG
                     VIRYLGYFQTYNALILTMQASLPKVLRFSACAGLIYLGYTFCGWIVLGPYHEKFENLN
                     IVAECLFSLVNGDDMFATFAQIQQKSLLVWLFSRLYLYSFISLFIYMVLSLFIALITD
                     SYHTIKKYQQNGFPETDLQKFLKESGSKEGYQKEPSALLPCFCCLRRRGSDDHLVLVD
                     "
     exon            127..286
                     /gene="Mcoln2"
                     /inference="alignment:Splign:2.1.0"
     exon            287..460
                     /gene="Mcoln2"
                     /inference="alignment:Splign:2.1.0"
     exon            461..614
                     /gene="Mcoln2"
                     /inference="alignment:Splign:2.1.0"
     exon            615..699
                     /gene="Mcoln2"
                     /inference="alignment:Splign:2.1.0"
     exon            700..796
                     /gene="Mcoln2"
                     /inference="alignment:Splign:2.1.0"
     exon            797..896
                     /gene="Mcoln2"
                     /inference="alignment:Splign:2.1.0"
     exon            897..1009
                     /gene="Mcoln2"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1159
                     /gene="Mcoln2"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..1261
                     /gene="Mcoln2"
                     /inference="alignment:Splign:2.1.0"
     exon            1262..1384
                     /gene="Mcoln2"
                     /inference="alignment:Splign:2.1.0"
     exon            1385..1591
                     /gene="Mcoln2"
                     /inference="alignment:Splign:2.1.0"
     exon            1592..1713
                     /gene="Mcoln2"
                     /inference="alignment:Splign:2.1.0"
     exon            1714..2517
                     /gene="Mcoln2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggatccgggt gtccgaacag tggtgactga gggaatctag ggtcgcgcca tgcccgaagg
       61 cgaagagacg ctggacctgc cagcgtggaa ccgcgccccg gacccagctt ggggtcccca
      121 gcacagagct gcagtggcgt ctcttgattc tgaggtgaag gaagagtgtc tgagggaaga
      181 cctgaagttc tacttcatga gtccctgtga gaaataccga gccagacgcc agatcccatg
      241 gaaactggcc ttgcagattt tgaagatagt catggtaacc acacagcttg ttcggtttgg
      301 cttaggtaac cagttggtgg tggctttcaa agaagataac actgttgctt ttaagcactt
      361 gtttttgaaa ggattttctg gagttgatga agatgactac agctgcagca tatacactca
      421 ggaggacgcc tacgagagca tcttttttgc tataaagcag tatcgccatc taaagaacat
      481 ttccctggcc acccttggtt atggaaaaag tgaagacaat agaactggct tgagattctg
      541 taagcagcac tacaagagcg gggccatgtt ttcttctaac gagaccctga acattgacag
      601 tgacattgag acagactgca ctcacctgga cctccaggtg ctcaccaagg accccgagga
      661 ctgggcacag gcatcgttct tcaggctgga ttttcatcgg ctcgtacaag tggatatctc
      721 ttttgccctc aaaggaattg acctacaggc agttcactcc cgagaggtac cagactgtta
      781 cctctttcag aatacgatta ccttcgacaa cacggcccac agtggaaaaa tcaaaatcta
      841 ctttaacagc gaggccaaca tagaagaatg taaacacatg aacttatctg ggtctcttca
      901 gagaagcacc cgctacgtcc tggtgtttga tgtgtttgtc attgcgatct gcctggcatc
      961 ccttatcctg tgcacaagat ccattgttct tgctctgagg ctgaggaaga gatttctaaa
     1021 cttcttcctg gagaagtaca aacaacacgt gtgtgatgct gaccggtggg agttcatcaa
     1081 tggatggtac gtcctggtca ctatcagcga cctcatgaca ataattggat ccatattgaa
     1141 gatggaaatc aaagccaaga acctcacaaa ctatgacctg tgcagcatcc tgctcgggac
     1201 gtcgacgctc cttgtctggg ttggagtcat ccgatatctg ggttactttc agacgtacaa
     1261 tgcgctcatt ttaaccatgc aggcctccct gcccaaagtg ctccggttca gcgcttgcgc
     1321 cggtttgatc tacctgggct acacgttctg cggttggatt gtcttagggc cgtaccacga
     1381 gaagtttgaa aacctgaaca tcgttgccga atgcctgttt tctctggtca acggtgatga
     1441 catgtttgcc acatttgctc agatccagca gaagagcctc ctggtgtggc tgttcagccg
     1501 tctctacttg tactccttca tcagcctctt catctacatg gtcctcagtc ttttcatcgc
     1561 gctcatcacc gattcgtacc acaccattaa gaaataccag cagaatgggt ttcctgaaac
     1621 ggatctgcag aaattcctga aggagagtgg tagcaaagaa gggtaccaga aggagccatc
     1681 agccttgctg ccctgtttct gctgtctgag gaggagagga agtgatgacc acttggttct
     1741 cgttgattaa aacccttggc taatgcccat caagtccaca cctcttcatg ctgtggttgt
     1801 acggagaggc ccagaggcag cagcagttca ttcaaagatt gtcctactaa gttgtggatc
     1861 cagaaggagg ggtgtccgtg agctcttgac gggaactgac ataccaaagt tacttttgat
     1921 aaacacagag tgtgaagagt aggcctctcc tgggagttaa tgtgagggca atgtgacaat
     1981 gaaattcagc aggagtctgg tcatttgtgc catcataatg ttgaaaggtt aaaaaaaagt
     2041 attccctttt ccaagttgtg taagcaatat ttaaaccctg gtcaaggtgt atgtttattt
     2101 ccaggaaaag attcatttca aaatgtgatc cttggattta aagacattca ttaattcatg
     2161 gtccacatag aaataaattt ggcttcaata ccaaattaag acttgaaact ggagaactga
     2221 taaaccatgt aaggctcaca ctcaaaacac tagcaggcag atatctagaa ctcagatcat
     2281 ggctggttgt actgtgagct tgcttcttta gcaggcatga catgcagtgt ccgttagcac
     2341 agagagagcg cctggctgcc ccctcaggca agcttccccg ccctgtgcac gtgatgagtg
     2401 agtggcccta aacttggcgt ggccacctat ttcatgagtc agctccactg tggtggggct
     2461 ttgcccttgt catggaagga aatgtggatt tttccttaaa taaatttatt ttcgtgaaaa
     2521 aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
