LOCUS       NM_001024340            3200 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus minichromosome maintenance domain containing 2
            (Mcmdc2), mRNA.
ACCESSION   NM_001024340 XM_575751
VERSION     NM_001024340.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3200)
  AUTHORS   Finsterbusch,F., Ravindranathan,R., Dereli,I., Stanzione,M.,
            Trankner,D. and Toth,A.
  TITLE     Alignment of Homologous Chromosomes and Effective Repair of
            Programmed DNA Double-Strand Breaks during Mouse Meiosis Require
            the Minichromosome Maintenance Domain Containing 2 (MCMDC2) Protein
  JOURNAL   PLoS Genet 12 (10), e1006393 (2016)
   PUBMED   27760146
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC083882.1.
            
            On May 27, 2005 this sequence version replaced XM_575751.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083882.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5756307,
                                           SAMEA5760383 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3200              BC083882.1         1-3200
FEATURES             Location/Qualifiers
     source          1..3200
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q11"
     gene            1..3200
                     /gene="Mcmdc2"
                     /note="minichromosome maintenance domain containing 2"
                     /db_xref="GeneID:500392"
                     /db_xref="RGD:1561068"
     exon            1..21
                     /gene="Mcmdc2"
                     /inference="alignment:Splign:2.1.0"
     exon            22..133
                     /gene="Mcmdc2"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..2085
                     /gene="Mcmdc2"
                     /note="MCM domain-containing protein C8orf45 homolog; MCM
                     domain-containing protein 2; uncharacterized protein
                     C8orf45 homolog"
                     /codon_start=1
                     /product="minichromosome maintenance domain-containing
                     protein 2"
                     /protein_id="NP_001019511.2"
                     /db_xref="GeneID:500392"
                     /db_xref="RGD:1561068"
                     /translation="MEKMGKLPMKEAALVYLDRSGGLQKFMDDCKYYNDSKQSYAVYR
                     FSILINPCDVVELDAELGNHILHHPLKAAQVFQSVCFVAVKTLSLIGKLQTETQINIV
                     LKLTHLPSLPSYSLDLCEFPLNYASQRFYMMQGIVIAMTTVTKYTQGARFLCSDEVCP
                     FSKGFQYIRVHVPGATESATVRNDFLCRLCSSSLQEDRKFRVLGDKQIIEIITTKVLH
                     AFQGDPKNQPFRFQSLSVFLRDELVNKMKIGNEYKIIGIPVCVKTSQTALCVEANSIT
                     PYTAKVPSGISDNFRCLLSLTSSSCWRFTAILANVFASHIVPLGTYNLLKLCLLMSLV
                     QTRDCSSERENCLDILVITSDTLLVDRLLNFSMNLVSRGIRHPVCTEVFPTVSRDKYG
                     TGAVSIQAGSALLARGGVCFIGDLTSHKKDKLEQLQSALESRSVTVFIPGKKFGDDFD
                     QQMTFPIQCSFWSFVDMDSSSRRNVQKASTLIGQMDCSLIPANLAEAFGLLVNCKESS
                     PCHPLLPTVQHTLKKAVDPKGPPYLASKQFTTEDFEKLLAFAKNLNVEFSLEAERMIH
                     GYYLASRRIRTDSIHGSKLSANALKYLVSLSEAHARLNLRNKVLREDVLIAALLFEIS
                     LTLKYGATAFCVAPNALFPFELYDEDYLEQRDLYLTQCQQQLQHFIATCGPGTAVLSS
                     DE"
     exon            134..264
                     /gene="Mcmdc2"
                     /inference="alignment:Splign:2.1.0"
     exon            265..324
                     /gene="Mcmdc2"
                     /inference="alignment:Splign:2.1.0"
     exon            325..520
                     /gene="Mcmdc2"
                     /inference="alignment:Splign:2.1.0"
     exon            521..643
                     /gene="Mcmdc2"
                     /inference="alignment:Splign:2.1.0"
     exon            644..748
                     /gene="Mcmdc2"
                     /inference="alignment:Splign:2.1.0"
     exon            749..874
                     /gene="Mcmdc2"
                     /inference="alignment:Splign:2.1.0"
     exon            875..1112
                     /gene="Mcmdc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1113..1318
                     /gene="Mcmdc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1319..1485
                     /gene="Mcmdc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1486..1665
                     /gene="Mcmdc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1666..1808
                     /gene="Mcmdc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1809..1918
                     /gene="Mcmdc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1919..3173
                     /gene="Mcmdc2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cacgcgggtc ctgcggtgca gattaccaac atggagaaga tggggaagct tccaatgaaa
       61 gaggcagccc ttgtctacct tgacagaagt ggaggcctcc aaaagtttat ggacgactgc
      121 aagtactaca atgattcaaa acaaagctat gctgtctacc ggttcagtat tttaataaac
      181 ccctgtgacg ttgtcgaatt agatgccgaa cttggcaatc acatcttaca ccatccttta
      241 aaagccgctc aagttttcca atcagtctgc tttgttgctg ttaagactct ctcgttaatt
      301 ggaaagttac agactgaaac tcaaatcaat attgtgctga agttaacaca tttaccgtcc
      361 ctgccaagct atagtcttga tctttgtgag tttccactta attatgcgtc tcagagattt
      421 tatatgatgc aggggattgt gattgccatg acaactgtaa ccaagtacac acaaggcgca
      481 aggttcctct gttcagatga agtatgtcct ttctcaaaag gatttcaata tataagagtc
      541 catgtgcccg gtgctacaga atctgcaaca gtaagaaatg actttttatg ccgtctctgt
      601 tcatcttcac ttcaagaaga cagaaaattt agagtacttg gtgataaaca gataatcgaa
      661 ataatcacca caaaagtcct tcatgctttt caaggagatc ctaaaaacca gccatttaga
      721 tttcagtcgc ttagtgtttt cctaagagat gaactagtga ataagatgaa aataggaaat
      781 gaatataaaa ttattggaat tccagtctgt gtcaaaactt cacaaactgc tctctgtgta
      841 gaagcaaata gtatcactcc ttacacagca aaagttcctt caggaattag tgacaacttc
      901 aggtgtctcc tctccctgac gtccagctca tgctggagat tcacagcaat actggccaat
      961 gtctttgcat cacatattgt tcctctggga acttacaatt tgctcaaact ctgtttgctg
     1021 atgagcctag tccagacgag agactgcagc agtgagcgag aaaactgctt ggatatttta
     1081 gttataacca gtgacactct gcttgtagac agacttttga attttagcat gaaccttgtg
     1141 tcccgtggca tacgtcatcc tgtctgtact gaagtttttc ctactgtgtc cagagataaa
     1201 tatggaactg gagcagtaag cattcaagct ggcagtgctt tgcttgctag gggtggtgtc
     1261 tgcttcatag gagacctaac atcacacaaa aaggataaac tggaacagct ccagtcagct
     1321 ttggagagca gaagcgtcac agtgttcatc ccaggaaaga agtttgggga tgatttcgat
     1381 cagcaaatga cttttcccat tcaatgcagt ttttggtctt ttgttgatat ggattcatct
     1441 tcaaggagaa atgtacagaa agccagtact ctgattggtc agatggattg cagtttgatt
     1501 ccagccaacc ttgcagaggc gtttggattg ttggttaact gcaaggagtc ttctccgtgc
     1561 cacccacttc ttcctactgt gcaacacact ttaaagaaag cggtggatcc taaggggccg
     1621 ccttatttag cttctaaaca gttcacaact gaagattttg agaagctact ggcgtttgca
     1681 aagaatttga atgtggaatt cagtttggag gcagaaagaa tgattcatgg ctattatcta
     1741 gcgagtcgca gaatcagaac agattctata catggatcaa agctgtcagc aaatgcatta
     1801 aaatatttag tttctttatc tgaagctcac gctcgactga acttaaggaa taaagtgctc
     1861 agagaagatg tactaattgc agccttattg ttcgaaatat ccctcacatt gaaatatggg
     1921 gccaccgcgt tttgtgttgc tcccaacgca ctatttccat ttgagctgta tgatgaggac
     1981 tacttagagc agagagatct ctacctgact cagtgccaac agcagctcca acacttcatt
     2041 gccacatgtg gacccgggac agctgtcctt tctagtgacg aataagcaag ttagagttac
     2101 ttcccaggcc tccacaaacc tttgtaaatg ggagtggttt tggcgtaagg gtccagatgt
     2161 atcatctcag ttattggata gaatgccact gagggtatga aatgtggccc ccttcattat
     2221 tacaaatatg caaataaccc aacatccaaa accaatgtta ccaaggagct tcacaccaga
     2281 aacttcctgg tcacccatat atatatacat acagtacagt atgaaaaagg ttctgtccat
     2341 cccacccatc aggtagcaat gctttacata cataaccaga ttacgcttgt taaaatttac
     2401 cagtgatgag ttcatatcac tgcaacttaa tgacccaaat atctgtgagg cctttgacac
     2461 gtgcattatg ggtgttactt tataaggcca gatgtgggaa tcctctatat cctcctgcta
     2521 catataatga aagtgacggg ggcatgtcgt ctttttgtca ggaggtgcta ctactccagg
     2581 gtcacacagc acttggtact tttaggtacc tgctctcaac agcaagttaa tgatatagta
     2641 catacaaatt aagacctgtt ttgtcctttt tcgtgatgtg gctaaatcta ggtctctatg
     2701 aagaacaaaa caattcttaa agagcaaaaa cagccacaac tggcaagtct aacattagga
     2761 attcctatca gggaatcaaa tccagagttc tgtgccagct aagaaaccac ttccccaccc
     2821 cttgcaagcc ccaagtcatt accatgttgc tcaattttta agctatttac taaacttagg
     2881 gattctagtg gttaaagact ttgccaagtc ttcaccagag gaaaaccagt cttaagagtt
     2941 ctcaagtggt ctagtcactt tcttccccac ggtgtattgg tgtactggcc atcaggattg
     3001 cttgtgttga caaaaagtaa atgaagtctg cagctcatga aggatgaggt ttattttact
     3061 atgagaatgg tgttttaaag acacgcattt taaagaaact aatgctcata gcaattaaaa
     3121 tcgtttattt ctacataaca tattgatacc aaattaaata ctaattttca ccaaaaaaaa
     3181 aaaaaaaaaa aaaaaaaaaa
//
