LOCUS       NM_001106382            6232 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus minichromosome maintenance complex component 3
            associated protein (Mcm3ap), mRNA.
ACCESSION   NM_001106382 XM_001079670 XM_215376
VERSION     NM_001106382.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6232)
  AUTHORS   Chen,K., Xi,M., Huang,Q., Wu,H., Lu,G., Song,S. and Shi,W.
  TITLE     Long non-coding RNA MCM3AP antisense RNA 1 silencing upregulates
            microRNA-24-3p to accelerate proliferation and migration of
            vascular endothelial cells in myocardial infarction rats by
            reducing EIF4G2
  JOURNAL   Cell Cycle 21 (7), 674-684 (2022)
   PUBMED   35113004
  REMARK    GeneRIF: Long non-coding RNA MCM3AP antisense RNA 1 silencing
            upregulates microRNA-24-3p to accelerate proliferation and
            migration of vascular endothelial cells in myocardial infarction
            rats by reducing EIF4G2.
REFERENCE   2  (bases 1 to 6232)
  AUTHORS   Umlauf,D., Bonnet,J., Waharte,F., Fournier,M., Stierle,M.,
            Fischer,B., Brino,L., Devys,D. and Tora,L.
  TITLE     The human TREX-2 complex is stably associated with the nuclear pore
            basket
  JOURNAL   J Cell Sci 126 (Pt 12), 2656-2667 (2013)
   PUBMED   23591820
REFERENCE   3  (bases 1 to 6232)
  AUTHORS   Singh,S.K., Maeda,K., Eid,M.M., Almofty,S.A., Ono,M., Pham,P.,
            Goodman,M.F. and Sakaguchi,N.
  TITLE     GANP regulates recruitment of AID to immunoglobulin variable
            regions by modulating transcription and nucleosome occupancy
  JOURNAL   Nat Commun 4, 1830 (2013)
   PUBMED   23652018
REFERENCE   4  (bases 1 to 6232)
  AUTHORS   Hu,Y.H., Warnatz,H.J., Vanhecke,D., Wagner,F., Fiebitz,A.,
            Thamm,S., Kahlem,P., Lehrach,H., Yaspo,M.L. and Janitz,M.
  TITLE     Cell array-based intracellular localization screening reveals novel
            functional features of human chromosome 21 proteins
  JOURNAL   BMC Genomics 7, 155 (2006)
   PUBMED   16780588
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6232)
  AUTHORS   Kuwahara,K., Yoshida,M., Kondo,E., Sakata,A., Watanabe,Y., Abe,E.,
            Kouno,Y., Tomiyasu,S., Fujimura,S., Tokuhisa,T., Kimura,H.,
            Ezaki,T. and Sakaguchi,N.
  TITLE     A novel nuclear phosphoprotein, GANP, is up-regulated in
            centrocytes of the germinal center and associated with MCM3, a
            protein essential for DNA replication
  JOURNAL   Blood 95 (7), 2321-2328 (2000)
   PUBMED   10733502
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473988.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_215376.4, XM_001079670.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..6232
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..6232
                     /gene="Mcm3ap"
                     /note="minichromosome maintenance complex component 3
                     associated protein"
                     /db_xref="GeneID:294339"
                     /db_xref="RGD:1306834"
     exon            1..268
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            269..1586
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     CDS             374..6100
                     /gene="Mcm3ap"
                     /EC_number="2.3.1.48"
                     /note="minichromosome maintenance deficient 3 associated
                     protein; 80 kDa MCM3-associated protein"
                     /codon_start=1
                     /product="germinal-center associated nuclear protein"
                     /protein_id="NP_001099852.1"
                     /db_xref="GeneID:294339"
                     /db_xref="RGD:1306834"
                     /translation="MNPVNPFSGQQPGAFAVSSSATGTFQTKSPFRFGQPSLFGQNNQ
                     ASKSLGFSQVPSFATPSGGSHSSSLPAFGLTQTSSVGLFSGLESTPSFAATSGPSSSS
                     VPGNTAFSFKSASSVGVFSSGPTFGPETGDVAGSGFRKTEFKFKPLENAVFKPILGAE
                     SEPEKTQSQIASGFFTFSHPVSSGSGGLTPFSFPQVTNSSATSSSFIFSKPVTSNTSA
                     FAPALSNQNIEEEKRGPKSVFGGLNSSFSTFPMASPGSLGEPFPTNKTSIRQGGEEAI
                     SQVESHPALMKGLKRKEDQDRSPRRHCHEAAEDSDPLSRGDHPPDKRPVRLNRPRGGT
                     LFGRTIQEVFKSNKEAGRLGSKESKKDSGFVESGESDHVAIPGGSQSTLVTSRLPAVN
                     KEEETEGRDEKEDSLRGTSVRQSKRSESTDSLGGMSSLELTAIQCKNIPDYLNDRAIL
                     EKHFSKIAKVQRVFTRRSKKLAVIHFFDHASAALARKKGKGLHKDMAIFWHKKKISPS
                     KKPFSLKEKQLGEGEASQGIEDSPFQHSPLGKPIVRPATGSLLNKSSPVKKPGLLKIH
                     QFEADPFDSGSEGSEGLGSCVSSLSTLIGTVADTSEEKYRLLDQRDRIMRQARVKRTD
                     LDKARAFVGTCPDMCPEKERYLRETRSQLSVFEVVPGTDQVDHAAAVKEYSRSSADQE
                     EPLPHELRPSAVLSRTMDYLVTQIMDQKEGSLRDWYDFVWNRTRGIRKDITQQHLCDP
                     LTVSLIEKCTRFHIHCAHFMCEEPMSSFDAKINNENMTKCLQSLKEMYQDLRNKGVFC
                     ASEAEFQGYNVLLNLNKGDILREVQQFHPDVRNSPEVDFAVQAFAALNSNNFVRFFKL
                     VQSASYLNACLLHCYFNQIRKDALRALNVAYTVSTQRSTVFPLDGVVRMLLFRDCEEA
                     TSFLNYHGLTVADGCVELNRSAFLEPEGLYKARKSVFIGRKLTVSVGEVVNGGPLPPV
                     PRHTPVCSFNSQNKYVGESLATELPISAQRSGGDSAGGGRGEEVEAEVDVPPLAVLPQ
                     LPPAPSATPVPHVQPLTQAVTPSLFQASTQPEVLLPKPVPVYSDSDLVQVVDELIQEA
                     LQVDCEEVSSAGAAYVAAALGVSNAAVEDLITAATTGILRHVAAEEVSMERQRVEEEK
                     RRAEEERLKQERELMLTQLSKGLAAELTELTVTECVWETCSQELKSAVETDQKVRVAR
                     CCEAVCTHLVDLFLAEEIFQTAKETLQELQCFCKYLQRWRGAVAARKKLRRQMRAFPA
                     APCCVDVNDRLQALVPSAECPITEENLAKGLLDLGHAGKVGISCTRLRRLRNKTAHQM
                     KVQHFHQQLLSNAAWAPLDLPSFVAEHLPVKQKRIFWKLVLVLPDGEEQTPESPGRIL
                     ENWLKVKFTGDGSLVDDTRDNAGDIQTLSVFNTLSSKGDQTVSVNVCIKVARGTLSDS
                     ALDAVETRKDLLGASGLMLLLPPKVKSEDVAEEDLYWLSALLQLKQLLQAKPFQPALP
                     LVVLVPSSRGDSTGKGVEDGLMLQDLISAKLISDYIVVEIPDFVNDLHGTVKVSGAVQ
                     WLISRCPQALDLCCQTLIQYVEDGISREFSGRFFHDRRERRLGSLASQEPSAIIELFN
                     SVLQFLASVVSSEQLGDISWPVTEFAEVGGSQLLPHLHWNSPEHLAWLKQAVLGFQLP
                     QMDLPPPAALWLPVCSMVIQYTSQIPSSCRTQPVLRSQVESLLCRTYQKWKSKSLCPG
                     QQSGPSVAEIPWDDIITLCINHKLRDWTPPRLPVTLDALSEDGQICVYFFKNRLRKYT
                     VPLSWEQARMQTQRELQLSQGWFEDQLQQWLSRDSQAFTESARLPLYLPQTLVSYPDA
                     IKTQTKVKTSTSPQNAGTGDHVRFSEASDTSLTEKLKHLERLIQSSRAEEAASELHLS
                     ALLDMVDI"
     exon            1587..1810
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            1811..1889
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            1890..2034
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            2035..2225
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            2226..2365
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            2366..2563
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            2564..2832
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            2833..2995
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            2996..3156
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            3157..3398
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            3399..3598
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            3599..3699
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            3700..3831
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            3832..3945
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            3946..4098
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            4099..4296
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            4297..4365
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            4366..4500
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            4501..4654
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            4655..4913
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            4914..5011
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            5012..5402
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            5403..5660
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            5661..5790
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            5791..5941
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
     exon            5942..6232
                     /gene="Mcm3ap"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttatggtgc ggtgagccgg ctagcggccg aatgcagact ctgggcgagc ataagcgctt
       61 gcgacagtgg cgatatctgg cggaccggct ccttccgcgg cctctgcttt tctttgtgtt
      121 ctggccgagt tgctgaaggc ctggcttcac catcttcgct cgaaggcatc tgatagctag
      181 cgaccggttt cccgtgtgtt gcgagcatag gaaaaaaaaa ggctgttcgt tctagaccag
      241 agcatctcaa gttcgagtta atgagatggt tatcctaaga tgaaggagag cttccccaag
      301 caacagatag tttaaggaag agagcttgtt gtgtatagac cgtatttatt gccttcaagt
      361 aattgggttg aagatgaacc ctgtgaaccc cttcagtggg cagcagcccg gcgcctttgc
      421 ggtgtcttct agtgccacgg gaacatttca gactaagtca ccattccgat ttggccagcc
      481 ttcccttttt ggacagaaca accaagccag caagagcctg ggattttcac aggtaccgag
      541 ctttgcaaca ccctctggtg gaagccattc ttcctctttg ccagcctttg gacttaccca
      601 aacctcaagt gtgggacttt tctctggtct ggaatccaca ccttcttttg cagctacttc
      661 tgggccttca agttcatctg tgcccggaaa tacagcattc agcttcaagt cagcctccag
      721 tgttggggtt ttctcgagtg gccctacttt cgggccagaa actggagacg tagcaggttc
      781 tggttttagg aagacggagt tcaagtttaa acctctggaa aatgcagtct tcaaacccat
      841 actgggggcc gagtcagagc cggagaaaac ccagagccag attgcttctg ggtttttcac
      901 attttctcac cctgttagta gtgggtctgg gggcctcacc cccttttcct tcccgcaggt
      961 gacaaacagc tcagcaacta gttcaagttt tatcttttcg aaaccagtta ctagtaatac
     1021 gtctgccttc gcccctgctt tgtctaacca aaatatagag gaagagaaga ggggacccaa
     1081 gtcagtgttt gggggcttga atagtagctt cagtactttc cccatggcgt cacctggatc
     1141 tttgggggag cccttcccga ccaacaaaac aagcatccgc caaggaggtg aggaagccat
     1201 ctcccaggtg gagtcacatc ctgccctcat gaagggatta aagaggaaag aggaccagga
     1261 tcgctcccca agaagacatt gccacgaggc agcagaagac tcggaccccc tgtccagggg
     1321 tgaccatccc ccagataaac ggccagtccg cctgaataga ccccggggag gcactctgtt
     1381 tggtcggacg atacaagagg tcttcaaaag caataaagaa gcaggccgtc tgggcagcaa
     1441 ggaatccaaa aaggacagtg gctttgtgga atctggggaa agtgaccacg tggccatccc
     1501 aggagggagt cagtccaccc tggtaacttc ccggcttcca gctgtgaata aagaggaaga
     1561 aacagaaggt agagatgaaa aagaagattc tctccgggga acgtctgtgc ggcaaagtaa
     1621 aagaagcgag agcacagaca gcctgggggg catgtcgtct ttagagctca cggccatcca
     1681 gtgcaagaac atccccgact acctcaacga cagagccatc ctggagaaac acttcagcaa
     1741 gatcgctaag gttcagcggg tcttcaccag acgcagcaag aagctcgccg tgattcattt
     1801 ttttgatcat gcatctgcag ccctggctcg gaagaaagga aaaggtctgc ataaggacat
     1861 ggctatcttt tggcacaaga agaaaataag tcccagcaaa aaaccctttt ccctgaagga
     1921 gaagcagctt ggtgaaggtg aagccagcca aggcatagag gactctccct ttcagcactc
     1981 ccctctcggc aagcccatcg tgaggcctgc caccggcagc ctcctgaaca aaagctctcc
     2041 agtgaagaag cccggtcttc tgaagatcca ccagttcgag gcagatcctt ttgactctgg
     2101 atctgagggc tccgagggcc ttggttcttg tgtgtcatct cttagcaccc tgattgggac
     2161 tgtggctgac acatctgaag agaagtaccg ccttctggat cagagagacc gcatcatgcg
     2221 gcaagctcgg gtgaagagga cagacctgga caaagcaagg gcgttcgtgg ggacgtgccc
     2281 tgacatgtgt cctgagaagg agcggtacct gcgggagacc cggagccagc tgagcgtgtt
     2341 tgaagttgtc ccagggactg accaggtgga ccatgcagca gccgtgaagg agtacagccg
     2401 gtcctctgcg gatcaggagg agcccctgcc acatgagctg agaccctcag cagttctcag
     2461 caggaccatg gactacctag tgacccagat catggatcaa aaggaaggca gccttcggga
     2521 ctggtatgac ttcgtgtgga accgcacacg gggtatacgg aaggacatca cacagcagca
     2581 cctctgcgat cccctgacgg tgtctctgat cgagaagtgt acccgatttc acatccattg
     2641 tgcccacttt atgtgtgagg aacctatgtc ctccttcgat gccaagatca acaacgagaa
     2701 tatgaccaaa tgtctacaga gtctgaagga gatgtaccag gacctgagga acaagggggt
     2761 tttttgtgcc agcgaagcag agttccaggg ctacaatgtc ctgctcaatc ttaacaaagg
     2821 tgacattttg agagaggtgc agcagttcca ccctgatgtt aggaactccc cggaggtgga
     2881 cttcgctgtc caggcttttg ctgcattgaa cagcaataat ttcgtgagat tcttcaaact
     2941 ggtgcagtca gcttcttacc ttaatgcgtg cctgttgcac tgttacttta accagatccg
     3001 taaggatgcc ctccgggcac tcaatgtggc atacactgta agcacacagc gctctaccgt
     3061 cttccccctg gatggtgtcg tccgcatgct gctgttccga gattgtgaag aggcgaccag
     3121 cttcctcaat taccatggcc tcactgtggc tgatggctgt gttgagctga accggtcggc
     3181 attcttggaa cccgagggac tatacaaggc caggaagtca gtgtttattg gccggaagct
     3241 gacagtgtca gttggagaag ttgtgaatgg agggccactg cctcctgttc ctcgacacac
     3301 acctgtgtgc agctttaact cccagaataa gtatgtcggc gagagcctgg ctacagagct
     3361 gcccatcagc gctcagagat ctggtggcga ctcagcaggt ggtgggagag gagaggaggt
     3421 tgaggcggaa gtggatgtgc cgccactggc tgtcctccca cagctgcctc ctgcgccctc
     3481 agccacacca gtgcctcatg tccagccact gacccaagct gtgactccta gccttttcca
     3541 ggcctccacg cagcctgagg tgctgctgcc aaagcccgtg cctgtgtact ctgattcgga
     3601 cctagtacag gtggtggacg agctcatcca ggaggctctg caggtagact gtgaggaagt
     3661 cagctccgct ggggcagcct acgtagccgc agctctggga gtctccaatg ctgctgtgga
     3721 ggatctgata acagctgcca ccacaggcat tctgaggcac gttgcagctg aagaagtatc
     3781 catggaaagg cagagggtag aggaagaaaa gcgtcgggct gaagaggaaa ggttgaagca
     3841 agagagagaa ctgatgttaa ctcagctgag caagggcctg gccgcagagc tgacagaact
     3901 cacggtgaca gagtgtgtgt gggaaacctg ctcccaggag ttaaagagtg cagtagagac
     3961 agaccagaag gtccgcgtag cccgctgttg tgaagccgtc tgtacacact tggtggattt
     4021 gtttcttgct gaggaaattt tccagactgc aaaagagaca ctccaggaac tccagtgctt
     4081 ctgcaagtat ctacaaaggt ggaggggagc tgtcgcagcc cgaaagaaac tccggcgtca
     4141 gatgcgggcc ttccctgcag caccgtgctg tgtggatgtg aatgaccggc tgcaggcatt
     4201 agtgcccagt gcagagtgtc ccattactga ggagaacctg gccaagggcc ttttggacct
     4261 gggccatgcc gggaaagtgg gcatctcctg taccaggttg aggcggctta ggaacaagac
     4321 ggctcaccag atgaaggtcc agcacttcca ccagcagctg ctgagtaatg ctgcctgggc
     4381 acctctggac ctgccatcct ttgtggccga gcacctccct gtgaagcaga agcgaatatt
     4441 ttggaaactg gtgctggtgc tgcctgatgg agaagagcag actccagaga gtcctggcag
     4501 aatactagaa aattggttaa aggtcaagtt cacaggagat ggcagcctgg tggatgacac
     4561 acgagataat gctggtgaca tccagaccct ctcagtcttt aatacactca gcagtaaagg
     4621 ggatcaaaca gtttctgtca acgtgtgtat aaaggtggct cgtggcaccc tcagtgacag
     4681 cgccctcgat gccgtggaga cacggaagga cctgttggga gccagtgggc tcatgctgct
     4741 gcttcccccc aaagtgaaga gtgaggatgt agcagaggag gatctgtact ggctgtcggc
     4801 tttactgcag ctcaagcagc ttctccaggc caagcccttc cagcctgccc tgccactggt
     4861 ggtcctcgtg cccagctcca gaggagactc cacggggaag ggagtagagg acggtctgat
     4921 gttacaagat ttgatttcag ccaagctgat ttcagattac atcgttgttg agattcctga
     4981 ttttgttaac gatttacacg gcacagtgaa ggtttctgga gcagtccagt ggctgatctc
     5041 ccggtgccct caagccctag acctttgctg ccaaaccctt attcagtatg ttgaggatgg
     5101 gatcagccgt gagttcagtg gtcggttttt ccacgacagg agagagagac gcctgggcag
     5161 tctggcctcc caggagccta gcgccattat tgagttgttc aacagtgtgc tacagttcct
     5221 ggcctctgtg gtgtcctctg agcagctggg tgacatctcc tggcctgtca cggaatttgc
     5281 tgaggtggga ggcagccagc tacttcctca cttgcactgg aactcaccag agcatctagc
     5341 ttggctgaag caagctgtgc ttgggttcca gcttccacag atggatcttc cacccccagc
     5401 ggccctctgg ctccctgtgt gttccatggt gatccagtac acgtcccaga ttcccagctc
     5461 gtgcaggaca cagcctgtcc tgcggtccca ggtggagagc ctgctgtgca gaacatacca
     5521 gaagtggaag agcaagagcc tctgtccagg ccagcagtcg gggccttctg ttgccgagat
     5581 cccgtgggat gacatcatca ccttatgcat caatcacaag ctaagggact ggacgccccc
     5641 ccggctcccc gtcacattag atgcactgag tgaagatggt caaatatgtg tatatttttt
     5701 caaaaatcgt ctaaggaaat acactgttcc cttgtcatgg gagcaggcca gaatgcagac
     5761 ccagagggaa cttcagctga gtcaaggatg gtttgaagat caacttcagc aatggctatc
     5821 acgagactca caggccttca ccgagtcagc ccgccttcct ctctacctcc ctcagacatt
     5881 agtgtcttat cctgatgcca tcaaaactca gaccaaggtg aagacatcca caagtcctca
     5941 gaatgcaggg acaggagacc acgtgcggtt ctcagaggca tcagacacat ctctgactga
     6001 aaagctgaag cacctggaaa ggctaatcca aagttcaagg gcagaagaag cggcctctga
     6061 gctacatctc tctgcactgc tggacatggt ggacatatga gctgtctgat gagagagagt
     6121 tttcttcata atggcttgtc tgtattcaat tgtgttgtaa atgctgttgg aaatgtgact
     6181 attaattatg caaataaact tcttgaatca ttcaagagcc ctagtttcat gt
//
