LOCUS       NM_001106341             798 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Rattus norvegicus methylmalonyl CoA epimerase (Mcee), mRNA; nuclear
            gene for mitochondrial product.
ACCESSION   NM_001106341 XM_001058655 XM_215213
VERSION     NM_001106341.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 798)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 798)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   3  (bases 1 to 798)
  AUTHORS   Bobik,T.A. and Rasche,M.E.
  TITLE     Identification of the human methylmalonyl-CoA racemase gene based
            on the analysis of prokaryotic gene arrangements. Implications for
            decoding the human genome
  JOURNAL   J Biol Chem 276 (40), 37194-37198 (2001)
   PUBMED   11481338
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473980.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001058655.1, XM_215213.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CO571386.1, FM084585.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..798
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..798
                     /gene="Mcee"
                     /note="methylmalonyl CoA epimerase"
                     /db_xref="GeneID:293829"
                     /db_xref="RGD:1309966"
     exon            1..176
                     /gene="Mcee"
                     /inference="alignment:Splign:2.1.0"
     CDS             131..667
                     /gene="Mcee"
                     /EC_number="5.1.99.1"
                     /codon_start=1
                     /product="methylmalonyl-CoA epimerase, mitochondrial"
                     /protein_id="NP_001099811.1"
                     /db_xref="GeneID:293829"
                     /db_xref="RGD:1309966"
                     /translation="MRLVVKAAALAAGATGLFSRVQTPVAAGRSFSTSPSQHQASSPV
                     WKLGRLNHVAIAVPDLEKASSFYRDVLGAQVSEAVPLPEHGVSVVFVNLGNTKMELLH
                     PLGSDSPIAGFLQKNKAGGMHHVCIEVDNINAAVMDLKKQKIRSLSDEAKIGAHGKPV
                     IFLHPKDCGGVLVELEQA"
     exon            177..514
                     /gene="Mcee"
                     /inference="alignment:Splign:2.1.0"
     exon            515..798
                     /gene="Mcee"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agggtattgg ggcactgcct tcgagcccca cccttgtcct gttttccacg cccacctcag
       61 gccccgcccc ctgcccactc tcctagttgt ctttgcccgg ggtcgctgtg caagcttgta
      121 gcttcaggag atgaggctgg tagtgaaggc cgctgcgttg gctgcaggcg ctacagggct
      181 tttctccaga gtccagactc cagttgcagc agggagaagt ttttccacat caccgtccca
      241 gcatcaagca tccagtcctg tgtggaagct gggtcgactc aatcatgtgg ccatagcagt
      301 accagatttg gaaaaggcct cgtcatttta cagggatgtt ctaggggccc aggtgagtga
      361 ggcggtccct cttccggaac atggagtatc tgtggttttt gtcaacctgg gaaatacgaa
      421 gatggaactg cttcatccac tggggagtga tagtccgatc gcaggcttcc tgcagaagaa
      481 caaggctgga ggaatgcatc acgtctgcat cgaggtggac aacataaatg cagctgtgat
      541 ggatctgaag aaacagaaga tccgcagtct gagtgatgag gccaaaatag gggcacatgg
      601 gaaacccgtg attttcctcc atcccaaaga ctgtggtggg gtccttgtag aactggagca
      661 agcatgattt ataattgtga taaacttaat taatcaaccc aagtaaccct taacaatatt
      721 atcagatgta ttaggctact atttctacta ctttaaaact ttaattgcag aaagattaaa
      781 atatatacac atgtatat
//
