LOCUS       NM_001007759            1799 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus membrane associated ring-CH-type finger 3
            (Marchf3), mRNA.
ACCESSION   NM_001007759 XM_344688 XM_347280
VERSION     NM_001007759.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1799)
  AUTHORS   Fukuda,H., Nakamura,N. and Hirose,S.
  TITLE     MARCH-III Is a novel component of endosomes with properties similar
            to those of MARCH-II
  JOURNAL   J Biochem 139 (1), 137-145 (2006)
   PUBMED   16428329
REFERENCE   2  (bases 1 to 1799)
  AUTHORS   Bartee,E., Mansouri,M., Hovey Nerenberg,B.T., Gouveia,K. and
            Fruh,K.
  TITLE     Downregulation of major histocompatibility complex class I by human
            ubiquitin ligases related to viral immune evasion proteins
  JOURNAL   J Virol 78 (3), 1109-1120 (2004)
   PUBMED   14722266
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083738.1.
            
            On or before Nov 29, 2004 this sequence version replaced
            XM_344688.1, XM_347280.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083738.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16093047, SAMN16093049
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1799
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q12.1"
     gene            1..1799
                     /gene="Marchf3"
                     /gene_synonym="March3"
                     /note="membrane associated ring-CH-type finger 3"
                     /db_xref="GeneID:364878"
                     /db_xref="RGD:1359308"
     exon            1..185
                     /gene="Marchf3"
                     /gene_synonym="March3"
                     /inference="alignment:Splign:2.1.0"
     exon            186..429
                     /gene="Marchf3"
                     /gene_synonym="March3"
                     /inference="alignment:Splign:2.1.0"
     CDS             242..1003
                     /gene="Marchf3"
                     /gene_synonym="March3"
                     /EC_number="2.3.2.27"
                     /note="E3 ubiquitin-protein ligase MARCH3; MARCH-III;
                     membrane-associated RING-CH protein III;
                     membrane-associated RING finger protein 3;
                     membrane-associated ring finger (C3HC4) 3, E3 ubiquitin
                     protein ligase; RING-type E3 ubiquitin transferase MARCH3;
                     RING-type E3 ubiquitin transferase MARCHF3"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase MARCHF3"
                     /protein_id="NP_001007760.1"
                     /db_xref="GeneID:364878"
                     /db_xref="RGD:1359308"
                     /translation="MTTSRCSHLPEVLPDCTSSAAPVVKTVEDCGSLVNGQPQYVMQV
                     SAKDGQLLSTVVRTLATQSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLE
                     HWLSSSNTSYCELCHFRFAVERKPRPLVEWLRNPGPQHEKRTLFGDMVCFLFITPLAT
                     ISGWLCLRGAVDHLHFSSRLEAVGLIALTVALFTIYLFWTLVSFRYHCRLYNEWRRTN
                     QRVILLIPKSVNIPSNQQSLLGLHSVKRNSKETIV"
     exon            430..634
                     /gene="Marchf3"
                     /gene_synonym="March3"
                     /inference="alignment:Splign:2.1.0"
     exon            635..844
                     /gene="Marchf3"
                     /gene_synonym="March3"
                     /inference="alignment:Splign:2.1.0"
     exon            845..1772
                     /gene="Marchf3"
                     /gene_synonym="March3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcagcgcgc tctgggcgac tgctgagcca ggcgaccgcc gagcttgcgg cgatccccgt
       61 caggtgccca gtaaagccaa tgcgcccagg tccggcgggg caagagcagc cggcggttcc
      121 gggcaacttg ggactgagga tctgcagcag gggcgtggat ttggcgtctg gactgggcca
      181 ggaggatgga agtcctctat gagtgtggaa gccattaaca gagtaattgc tgtctgttgc
      241 catgacaacc agtcgctgca gtcacctgcc cgaagtcttg ccagactgca ccagctcagc
      301 tgcgcctgtg gtgaagacgg tggaggactg tggcagccta gtgaatgggc agccacagta
      361 tgtcatgcaa gtttcagcca aggacgggca gctgctgtca acagtagtgc ggactcttgc
      421 cacccagagc cccttcaatg accggccaat gtgcagaatc tgccatgagg gcagcagcca
      481 agaggactta ctctctccat gtgaatgtac tgggaccttg gggacaatcc atcggagctg
      541 cctggagcac tggctgtcat cctcaaatac cagctactgt gaactctgcc acttcaggtt
      601 tgcagtggag cgcaaaccca ggccgttagt ggagtggctt aggaaccctg gcccccagca
      661 tgagaagcgg actctgtttg gagacatggt gtgcttctta tttataacgc ccctggctac
      721 catctccggc tggctgtgcc ttcggggcgc cgtggaccac ctgcacttca gtagtcgact
      781 ggaagccgtg ggactgattg ctctcaccgt ggcactcttc acgatttacc tcttctggac
      841 actagtgtca tttaggtacc actgtcgatt gtacaatgaa tggcgtcgga ccaatcagag
      901 ggtgattctc ctcattccaa agtctgtcaa catcccttct aaccagcagt ccttgctggg
      961 gctccactca gtcaagagga actcaaagga gacaattgtt tgatgtctgt ggggtcagat
     1021 ggtggactcg ttgttggggg tttagaagtc tctgcactgg ggccatgcgc tgagccaccc
     1081 caaagccctt ccctccgtct ttgggtctaa gaacatctta ccgcatcgca tcgcctgagt
     1141 aaggaactca gccagaagga aacaatgctg tttgacttca aaatcatgga tgctgcactc
     1201 agatgacact cgctaagctg ccaaacatgt ctatctagca gatactgtaa ggactttctg
     1261 aacacctctc taacatacga ggaaggtagt cctgctgagg atgcaatgca attcttcctt
     1321 ttttattact atcgcaaata tatatatata taaatgtata atttagatga taatcaaaat
     1381 tgaaaagcca atgtacaaac tggtttcttg gtttagatgg gttttatttg ggttagttta
     1441 ttcatttccc cgtttctact gtggatcttt ggtggctaac ttgagggccc gaatggtctt
     1501 tttcatctct tttatgtccc ttattcaagg agacagcata attactgcag aacaagtcac
     1561 atttgaaggg tgttttgtac taaacctcat tcagttattc agtttttaaa agggaaaaaa
     1621 ggtgtggcaa ctcaccacac cacgcggtga gctgtttact taaatattaa ggaggaagtc
     1681 atggcgagat gctccctcct ttcaacttgt ttggtactga cagctgatag aagctatttt
     1741 ctaataataa atatctggtg tgtgaaagac aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
